502
BOOK
REVIEWS
of resistance to sulfanilamide and various antibiotics acquired between the years 1939 and 1945. The question of therapeutic effects of antibiotics in Rickettsial and virus diseases is discussed by RI. D. Eaton. The quintessence of 190, less than three years old, and publications concerned with “immunological reactions in viral diseases” have been extracted by H. Koprowski. 9. M. Kligman and E. D. DeLamater have condensed in twenty-four pages forty years of immunological studies in human (and B. tnlarense) is reviewed by L. Foshay, and “Brucellomycoses. “Tularemia” sis” by R. Castaneda. The volume ends by a critical review by P. F. Clark on the “Influence of Nutrition in Experimental Infection.” Needless to say, all this organized material is highly useful and welcome. A.
LWOFF,
Paris,
France
Histamine Antagonists. By FREDERICK LEONARD and CHARLES P. HU~RER. National Research Council, Washington, D. C., 1952. 122 pp. Price $1.50 In this Chemical-Biological Coordination Center Review No. 3, the authors discuss the pharmacological properties, methods of in vi&o and in tivo evaluation, methods of syntheses, structure-activity relationships, mechanism of action, and clinical application of histamine antagonists. More then 1000 compounds which have been tested for potent,ial antihistaminic activity are listed in 48 classified tables, including st,ructures, activities, and literature references. Emphasis is placed on the analysis of structure-activity correlations within the different classes of compounds, and on generalizations which can be deduced. The review contains 224 references. NATIONAL
RESEARCH
COUNCIL,
Washington,
D. C.
The Action of Hormones in Plants and Invertebrates. Edited by KENNETH V. Harvard University, Cambridge, Massachusetts. Academic Press Inc., New York, 1952. 228 pp. Price $5.80. THIMANN,
This convenient. volume has made available the chapters of The Hormones, Vol. I, 1948, dealing with the hormones of plants and invertebrates. The just,ification given for this by the editor is that many investigators have felt that these chapters should be available separately since they remain in the province of workers in somewhat separat.e fields and do not fit into the unified picture of endocrinology of mammals. The material has been brought up to date by changes either in the text or by the addition of material at the end of each chapter. Consequently, the volume will be most useful to workers in these branches of biology. Thimann has written two chapters, one on plant-growth hormones and the second on other plant hormones. Hormones in insects is a topic which is reviewed by Sharrer, and hormones in crustaceans is discussed by Brown. The excellence of illustrations and format have been maintained in this new volume and the critical treatment of various subjects is similar to that given in The Hornwnes. A complete index is provided. WILLIAM
H. FISHMAN,
Boston,
Massachusetts