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Histiocytic lymphoma of the cervix
(135)
PROTON RADIATION THERAPY OF PATIENTS WITH PROSTATIC CARCINOMA W.U. Shipley*, J.E. Tepper*, G.R.Prout, Jr.**, A.M.Koehler***, M. Goitein*, H.D. Suit*.
L.J.Verhey*,
*Dept. of Radiation Medicine, **dept. of Urology, ***Dept. of Physics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
The energy-modulated, 160 MeV proton beam of the Harvard University Cyclotron has been adapted for fractionated radiation therapy in the curative treatment of 14 patients with localized prostatic carcinoma. Following 5000 rads to the whole pelvis by 4-field high energy photon techniques, the proton beam has been used to deliver the 'boost' dose by a perineal technique. For proton treatments the patient is placed in a modfied lithotomy position and a probe inserted into the rectum in order to obtain accurate localization of the proton beam with respect to the tumor volume. The proton beam enters through a perineal portal and is angled slightly posteriorly so as to avoid irradiation of the anus. The beam is contoured three-dimensionally so that the treatment volume includes the prostate and seminal vesicles (when involved) and avoids completely the posterior rectal wall and other cephalad abdominal structures. For patient positioning, repeat radiographs are taken before treatment until surgical clips and/or gold seeds are aligned to within + 3mm of the designed position. A quantitative analysis of the radiation dose to the rectum and other pelvic structures for photon plus proton beam technique and for several Data on the acute reaction and the photon beam techniques will be compared. current status of the 14 patients treated by the proton beam techniques will be presented. (136)
HISTIOCYTIC LYMPHOMA OF THE CERVIX
Alan D. Steinfeld, M.D., Department of Radiation Oncology, Rhode Island Hospital, Providence, R.I.
Histiocytic lymphoma, when localized to a single extranodal site, can have a very good prognosis. A case of histiocytic lymphoma is presented. This case, as well as other cervical lymphomas gleaned from the literature, is discussed with regard to staging and evaluation of the patient. The roles of surgery, radiation therapy and combined treatment Of 16 patients reviewed, 1.2were alive and without evidence are considered. of disease for at least one year. The three approaches to treatment External beam appear similar in their ability to control the disease. radiation alone can control local disease.
132
PROTON RADIATION THERAPY OF PATIENTS WITH PROSTATIC CARCINOMA W.U. Shipley*, J.E. Tepper*, G.R.Prout, Jr.**, A.M.Koehler***, M. Goitein*, H.D. Suit*.
L.J.Verhey*,
*Dept. of Radiation Medicine, **dept. of Urology, ***Dept. of Physics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
The energy-modulated, 160 MeV proton beam of the Harvard University Cyclotron has been adapted for fractionated radiation therapy in the curative treatment of 14 patients with localized prostatic carcinoma. Following 5000 rads to the whole pelvis by 4-field high energy photon techniques, the proton beam has been used to deliver the 'boost' dose by a perineal technique. For proton treatments the patient is placed in a modfied lithotomy position and a probe inserted into the rectum in order to obtain accurate localization of the proton beam with respect to the tumor volume. The proton beam enters through a perineal portal and is angled slightly posteriorly so as to avoid irradiation of the anus. The beam is contoured three-dimensionally so that the treatment volume includes the prostate and seminal vesicles (when involved) and avoids completely the posterior rectal wall and other cephalad abdominal structures. For patient positioning, repeat radiographs are taken before treatment until surgical clips and/or gold seeds are aligned to within + 3mm of the designed position. A quantitative analysis of the radiation dose to the rectum and other pelvic structures for photon plus proton beam technique and for several Data on the acute reaction and the photon beam techniques will be compared. current status of the 14 patients treated by the proton beam techniques will be presented. (136)
HISTIOCYTIC LYMPHOMA OF THE CERVIX
Alan D. Steinfeld, M.D., Department of Radiation Oncology, Rhode Island Hospital, Providence, R.I.
Histiocytic lymphoma, when localized to a single extranodal site, can have a very good prognosis. A case of histiocytic lymphoma is presented. This case, as well as other cervical lymphomas gleaned from the literature, is discussed with regard to staging and evaluation of the patient. The roles of surgery, radiation therapy and combined treatment Of 16 patients reviewed, 1.2were alive and without evidence are considered. of disease for at least one year. The three approaches to treatment External beam appear similar in their ability to control the disease. radiation alone can control local disease.
132