- Email: [email protected]
Histological study of guided bone regeneration with the use of a polypropylene membrane
OOOO Volume 114, Number 4 oral hemangiomas were treated with a single session of Nd:YAG laser (4W, 20s, 100j/cm2) followed by unfocused laser biostimulation (1,25W, 50s, 93,75j/cm2). Moderate pain was reported until 48 hours following treatment, and after 7 days all patients presented with an asymptomatic necrotic area. Partial healing was noted after 15 days, and complete resolution of the lesions after 3 to 4 weeks. None of the patients reported the need for taking analgesics following the procedures, despite lesion size or location. In conclusion, a single-session Nd:YAG laser treatment is an effective therapeutic option for the management of oral hemangiomas, associated with clinical resolution and few adverse side effects.
HISTOLOGICAL STUDY OF GUIDED BONE REGENERATION WITH THE USE OF A POLYPROPYLENE MEMBRANE Weinfeld I1, Lucca L1 - 1UNIVERSIDADE DE SANTO AMARO - ODONTOLOGIA Background: A challenge in bone lesions is the cavity left after their removal. Objective: The purpose of the present study was to evaluate the use of a non-reabsorbable polypropylene membrane, commercially known as Bone Heal®, as a barrier utilized in these situations. Study design: Calvarial defects were prepared in 16 New Zealand female rabbits, covered (test group) or not (control group) with polypropylene membrane, in order to evaluate bone repair. After 21 and 42 days histological specimens were obtained and studied (HE – Mallory). Results: Both groups showed the same pattern of inflammatory response, yet the test group presented lower invasion of fibrous connective tissue and faster osteogenesis. Conclusion: Thus the polypropylene membrane appeared as a biocompatible material able to promote guided bone regeneration.
OROFACIAL FEATURES OF HYPOHIDROTIC ECTODERMAL DYSPLASIA Flores IL1, Aquino SN1, Paranaíba LMR2, Swerts MSO3, Coletta RD1, Martelli DRB, Júnior HM,3 - 1PIRACICABA DENTISTRY SCHOOL - FOP/UNICAMP - ORAL DIAGNOSIS DEPARTMENT, 2ALFENAS DENTISTRY SCHOOL - UNIFENAS - CENTER FOR REHABILITATION OF CRANIOFACIAL ANOMALIES, 3MONTES CLAROS DENTISTRY SCHOOL - UNIMONTES - CLINICAL STOMATOLOGY Background: Ectodermal dysplasia is a rare group of inherited disorders characterized by aplasia or dysplasia of tissues of ectodermal origin, such as hair, nails, teeth and skin. Hypohidrotic ectodermal dysplasia (HED) is perhaps the most known genodermatosis between the dysplasia ectodermal syndromes characterized by the abnormal development of sweat glands, teeth and hair. The most prevalent form is X-linked HED which is associated with mutations in the EDA gene. Objective: The aim of this study is describe a family with XLHED with emphasis on differences in orofacial features between members. Study design: Careful clinical examination was realized and five males affected presented classic phenotype of XLHED, as dental abnormalities, hypohydrosis, and craniofacial dysmorphologies. Results: Dental agenesis of the lateral maxillary incisors was principally feature in nine female heterozygous carriers.
ORAL ABSTRACT Abstracts e55 Conclusion: The diagnosis of the female carriers provided genetic counseling to affected families and adequate treatment as well following of these patients.
INTRAORAL PRIMARY MELANOMA: CASE REPORT Almeida JD1, Kaminagakura E2, Rodrigues LM2, Acay R3, Rosa LEB2, Carvalho YR2, Prado RF2 - 1FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS UNESP DEPARTAMENTO DE BIOCIÊNCIAS E DIAGNÓSTICO BUCAL, 2FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS -UNESP - DEPARTAMENTO DE BIOCIÊNCIAS E DIAGNÓSTICO BUCAL, 3FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS -UNESP PROGRAMA DE PÓS GRADUAÇÃO EM BIOPATOLOGIA BUCAL, FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS-UNESP A 55-year-old, Asian woman was referred from an acquaintance of her and saw the lesion informally. Patient reported that 2 months earlier, she started feeling pain in hard palate. She sought a dentist for root canal treatment in her maxillary left first molar with no resolution of the pain. She also reported abnormal local bleeding after flossing the area. Intraoral examination revealed a 5-centimeter-wide asymmetric black macula, with irregular borders and areas of proliferation of red color, located at hard palate and gingiva in left maxilla. Patient underwent incisional biopsy and histopathological examination of the specimen revealed melanocytic malignant neoplasia, featured by atypical epithelioid melanocytes showing nuclear alterations and melanin granules, and arranged in nests both within the epithelium, and in depth within the connective tissue. The diagnosis was then conclusive for malignant melanoma. The patient was immediately referred to a high-complexity hospital for proper management of the lesion.
IMMUNOHISTOCHEMICAL ANALYSIS OF KI-67 AND MCM-2 IN SQUAMOUS CELL CARCINOMAS OF THE TONGUE BETWEEN YOUNG AND OLDER PATIENTS Pereira JS1, Barroso KMA1, Nonaka CFW1, Pinto LP1, Souza LB1 - 1UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE - PATOLOGIA ORAL Objectives: to evaluate the immunoexpression of Ki-67 and Mcm-2 in squamous cell carcinoma of the tongue between young and older patients and to correlate it with prognostic indicators. Study design: Sample was composed of 20 cases under 40 years and 20 over 50 years. Clinical staging and histological grade of malignancy were obtained. Cell proliferation was evaluated through labeling indices (LI). Results: Most young patients were stages III/IV (n⫽1266.6%) and most older patients were stages I/II (n⫽11-68.8%) (p⬍.05). Mean Ki-67 LI in young and older patients was 43.8% and 42.5%, respectively (p⬎.05). Mean Mcm-2 LI was higher in older (65.9%) than in young patients (55.9%) (p⬍.05). We found no significant association between this immunoexpression and prognostic indicators. Conclusions: No differences in cell proliferation were observed between age groups, even though young patients presented more aggressive lesions. Ki-67 LI and Mcm-2 LI were not associated with prognostic indicators.
EXPRESSION OF C-JUN AND P-C-JUN IN POTENTIALLY MALIGNANT LESIONS IN SMOKERS AND
HISTOLOGICAL STUDY OF GUIDED BONE REGENERATION WITH THE USE OF A POLYPROPYLENE MEMBRANE Weinfeld I1, Lucca L1 - 1UNIVERSIDADE DE SANTO AMARO - ODONTOLOGIA Background: A challenge in bone lesions is the cavity left after their removal. Objective: The purpose of the present study was to evaluate the use of a non-reabsorbable polypropylene membrane, commercially known as Bone Heal®, as a barrier utilized in these situations. Study design: Calvarial defects were prepared in 16 New Zealand female rabbits, covered (test group) or not (control group) with polypropylene membrane, in order to evaluate bone repair. After 21 and 42 days histological specimens were obtained and studied (HE – Mallory). Results: Both groups showed the same pattern of inflammatory response, yet the test group presented lower invasion of fibrous connective tissue and faster osteogenesis. Conclusion: Thus the polypropylene membrane appeared as a biocompatible material able to promote guided bone regeneration.
OROFACIAL FEATURES OF HYPOHIDROTIC ECTODERMAL DYSPLASIA Flores IL1, Aquino SN1, Paranaíba LMR2, Swerts MSO3, Coletta RD1, Martelli DRB, Júnior HM,3 - 1PIRACICABA DENTISTRY SCHOOL - FOP/UNICAMP - ORAL DIAGNOSIS DEPARTMENT, 2ALFENAS DENTISTRY SCHOOL - UNIFENAS - CENTER FOR REHABILITATION OF CRANIOFACIAL ANOMALIES, 3MONTES CLAROS DENTISTRY SCHOOL - UNIMONTES - CLINICAL STOMATOLOGY Background: Ectodermal dysplasia is a rare group of inherited disorders characterized by aplasia or dysplasia of tissues of ectodermal origin, such as hair, nails, teeth and skin. Hypohidrotic ectodermal dysplasia (HED) is perhaps the most known genodermatosis between the dysplasia ectodermal syndromes characterized by the abnormal development of sweat glands, teeth and hair. The most prevalent form is X-linked HED which is associated with mutations in the EDA gene. Objective: The aim of this study is describe a family with XLHED with emphasis on differences in orofacial features between members. Study design: Careful clinical examination was realized and five males affected presented classic phenotype of XLHED, as dental abnormalities, hypohydrosis, and craniofacial dysmorphologies. Results: Dental agenesis of the lateral maxillary incisors was principally feature in nine female heterozygous carriers.
ORAL ABSTRACT Abstracts e55 Conclusion: The diagnosis of the female carriers provided genetic counseling to affected families and adequate treatment as well following of these patients.
INTRAORAL PRIMARY MELANOMA: CASE REPORT Almeida JD1, Kaminagakura E2, Rodrigues LM2, Acay R3, Rosa LEB2, Carvalho YR2, Prado RF2 - 1FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS UNESP DEPARTAMENTO DE BIOCIÊNCIAS E DIAGNÓSTICO BUCAL, 2FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS -UNESP - DEPARTAMENTO DE BIOCIÊNCIAS E DIAGNÓSTICO BUCAL, 3FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS -UNESP PROGRAMA DE PÓS GRADUAÇÃO EM BIOPATOLOGIA BUCAL, FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS-UNESP A 55-year-old, Asian woman was referred from an acquaintance of her and saw the lesion informally. Patient reported that 2 months earlier, she started feeling pain in hard palate. She sought a dentist for root canal treatment in her maxillary left first molar with no resolution of the pain. She also reported abnormal local bleeding after flossing the area. Intraoral examination revealed a 5-centimeter-wide asymmetric black macula, with irregular borders and areas of proliferation of red color, located at hard palate and gingiva in left maxilla. Patient underwent incisional biopsy and histopathological examination of the specimen revealed melanocytic malignant neoplasia, featured by atypical epithelioid melanocytes showing nuclear alterations and melanin granules, and arranged in nests both within the epithelium, and in depth within the connective tissue. The diagnosis was then conclusive for malignant melanoma. The patient was immediately referred to a high-complexity hospital for proper management of the lesion.
IMMUNOHISTOCHEMICAL ANALYSIS OF KI-67 AND MCM-2 IN SQUAMOUS CELL CARCINOMAS OF THE TONGUE BETWEEN YOUNG AND OLDER PATIENTS Pereira JS1, Barroso KMA1, Nonaka CFW1, Pinto LP1, Souza LB1 - 1UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE - PATOLOGIA ORAL Objectives: to evaluate the immunoexpression of Ki-67 and Mcm-2 in squamous cell carcinoma of the tongue between young and older patients and to correlate it with prognostic indicators. Study design: Sample was composed of 20 cases under 40 years and 20 over 50 years. Clinical staging and histological grade of malignancy were obtained. Cell proliferation was evaluated through labeling indices (LI). Results: Most young patients were stages III/IV (n⫽1266.6%) and most older patients were stages I/II (n⫽11-68.8%) (p⬍.05). Mean Ki-67 LI in young and older patients was 43.8% and 42.5%, respectively (p⬎.05). Mean Mcm-2 LI was higher in older (65.9%) than in young patients (55.9%) (p⬍.05). We found no significant association between this immunoexpression and prognostic indicators. Conclusions: No differences in cell proliferation were observed between age groups, even though young patients presented more aggressive lesions. Ki-67 LI and Mcm-2 LI were not associated with prognostic indicators.
EXPRESSION OF C-JUN AND P-C-JUN IN POTENTIALLY MALIGNANT LESIONS IN SMOKERS AND