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HLA-A, -B and -Cw allele frequencies in a Nadar population from Tamil Nadu, India
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HLA-A, -B and -Cw Allele Frequencies in a Nadar Population from Tamil Nadu, India U. Shankarkumar HLA department, Institute of Immunohaematology, KEM Hospital, Mumbai, India E-mail: [email protected] This population from the Tamil Nadu state of India, Latitude 8 –13N Longitude 77– 80E consisted of 61 Indo-European individuals. The individuals were drawn from an urban and rural environment and HLA alleles were determined using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 62, 542– 47, 2003. The Nadars are a Tamil-speaking Dravidian caste, considered to be one of the earliest inhabitants of South India. Human Immunology 65, 958 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency A*0101 0.09 A*020101 0.107 A*030101 0.205 A*110101 0.098 A*24020101 0.156 A*2611N 0.016 A*310102 0.189 A*3303 0.066 A*680101 0.074 B*0707 0.016 B*1304 0.016 B*15010101 0.172 B*1508 0.033 B*2705 0.041 B*3501 0.148 B*3503 0.025 B*3701 0.09 B*4006 0.09 B*4406 0.074 B*510101 0.156 B*5603 0.057 B*5701 0.082 Cw*0102 0.082 Cw*020202 0.156 Cw*0303 0.074 Cw*04010101 0.213 Cw*0501 0.016 Cw*0602 0.09 Cw*070101 0.107 Cw*0702 0.148 Cw*120201 0.049 Cw*140201 0.033 Cw*150201 0.033 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA-A, -B, -Cw, -DQA1, -DQB1 and -DRB1 Alleles and KIR Alleles in a Hindu Population from Punjab, India R. Rajalingam1,2,3*, P. Parham2 and N.K. Mehra3 1
UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California at Los Angeles, Los Angeles, California, USA 2 Department of Structural Biology, Microbiology and Immunology, Stanford University, Stanford, California, USA 3 Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India E-mail: *[email protected] This population from the North Indian states of Punjab, Haryana, Utter Pradesh and Delhi, Latitude 25–28N Longitude 74 – 81E consisted of 72 Hindu individuals. The individuals were drawn from an urban environment where the grandparents had also lived. HLA-A, -B and -DRB1 alleles were characterised by sequence based typing, HLA-C, -DQA1, -DQB1, and KIR alleles by sequence specific primers. Only 52 typed for HLA-A and -B, 34 typed for HLA-C, 54 typed for HLA-DRB1, 67 typed for HLA-DQB1. Human Immunology 65, 958 –960 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*0101 A*0201 A*0205 A*0206 A*0209 A*0211 A*0301 A*0302 A*1101 A*1104 A*2301 A*24020101 A*24020102L A*2403 A*2407 A*2601 A*2901 A*310102
Gene frequency 0.115 0.058 0.010 0.029 0.01 0.067 0.058 0.01 0.125 0.01 0.01 0.192 0.010 0.010 0.010 0.019 0.019 0.019 0198-8859/04/$–see front matter
HLA-A, -B and -Cw Allele Frequencies in a Nadar Population from Tamil Nadu, India U. Shankarkumar HLA department, Institute of Immunohaematology, KEM Hospital, Mumbai, India E-mail: [email protected] This population from the Tamil Nadu state of India, Latitude 8 –13N Longitude 77– 80E consisted of 61 Indo-European individuals. The individuals were drawn from an urban and rural environment and HLA alleles were determined using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 62, 542– 47, 2003. The Nadars are a Tamil-speaking Dravidian caste, considered to be one of the earliest inhabitants of South India. Human Immunology 65, 958 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency A*0101 0.09 A*020101 0.107 A*030101 0.205 A*110101 0.098 A*24020101 0.156 A*2611N 0.016 A*310102 0.189 A*3303 0.066 A*680101 0.074 B*0707 0.016 B*1304 0.016 B*15010101 0.172 B*1508 0.033 B*2705 0.041 B*3501 0.148 B*3503 0.025 B*3701 0.09 B*4006 0.09 B*4406 0.074 B*510101 0.156 B*5603 0.057 B*5701 0.082 Cw*0102 0.082 Cw*020202 0.156 Cw*0303 0.074 Cw*04010101 0.213 Cw*0501 0.016 Cw*0602 0.09 Cw*070101 0.107 Cw*0702 0.148 Cw*120201 0.049 Cw*140201 0.033 Cw*150201 0.033 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA-A, -B, -Cw, -DQA1, -DQB1 and -DRB1 Alleles and KIR Alleles in a Hindu Population from Punjab, India R. Rajalingam1,2,3*, P. Parham2 and N.K. Mehra3 1
UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California at Los Angeles, Los Angeles, California, USA 2 Department of Structural Biology, Microbiology and Immunology, Stanford University, Stanford, California, USA 3 Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India E-mail: *[email protected] This population from the North Indian states of Punjab, Haryana, Utter Pradesh and Delhi, Latitude 25–28N Longitude 74 – 81E consisted of 72 Hindu individuals. The individuals were drawn from an urban environment where the grandparents had also lived. HLA-A, -B and -DRB1 alleles were characterised by sequence based typing, HLA-C, -DQA1, -DQB1, and KIR alleles by sequence specific primers. Only 52 typed for HLA-A and -B, 34 typed for HLA-C, 54 typed for HLA-DRB1, 67 typed for HLA-DQB1. Human Immunology 65, 958 –960 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*0101 A*0201 A*0205 A*0206 A*0209 A*0211 A*0301 A*0302 A*1101 A*1104 A*2301 A*24020101 A*24020102L A*2403 A*2407 A*2601 A*2901 A*310102
Gene frequency 0.115 0.058 0.010 0.029 0.01 0.067 0.058 0.01 0.125 0.01 0.01 0.192 0.010 0.010 0.010 0.019 0.019 0.019 0198-8859/04/$–see front matter