- Email: [email protected]
HLA-DQB1 and -DRB1 allele frequencies in a population from Macedonia
1002
Allele Gene frequency DRB1*0401 0.013 DRB1*0402 0.019 DRB1*0403 0.019 DRB1*0404 0.010 DRB1*0405 0.010 DRB1*0407 0.013 DRB1*0408 0.003 DRB1*0701 0.073 DRB1*0801 0.019 DRB1*0804 0.003 DRB1*0806 0.003 DRB1*090102 0.006 DRB1*1001 0.019 DRB1*1101 0.092 DRB1*1103 0.013 DRB1*1104 0.139 DRB1*1201 0.013 DRB1*1301 0.073 DRB1*1302 0.032 DRB1*1307 0.003 DRB1*1401 0.029 DRB1*1404 0.003 DRB1*1501 0.044 DRB1*1502 0.016 DRB1*1601 0.149 DRB1*1602 0.029
HLA-DQB1 and -DRB1 Allele Frequencies in a Population from Macedonia A. Hristova-Dimceva Institute of Blood Transfusion, Skopje, Republic of Macedonia E-mail: [email protected] This population from Macedonia, Latitude 42N Longitude 21E consisted of 80 Caucasian individuals from different regions of Macedonia. In the Republic of Macedonia the majority of the 2 million inhabitants are of Slavic origin, have the Christian Orthodox religion and speak the Macedonian language. Minority populations in Macedonia are formed by Albanians, Turks, Gypsies, Serbs and Vlachs. The individuals were drawn from an urban and rural environment and HLA alleles were determined using sequence specific primers. The results have previously been published in Tissue Antigens 55, 53–56, 2000. Human Immunology 65, 1002–1003 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency DQB1*0201 0.072 DQB1*0202 0.012 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency DQB1*0301 0.321 DQB1*0302 0.066 DQB1*0303 0.012 DQB1*0304 0.006 DQB1*0402 0.012 DQB1*0501 0.062 DQB1*0502 0.142 DQB1*0503 0.072 DQB1*0601 0.019 DQB1*0602 0.056 DQB1*0603 0.072 DQB1*0604 0.037 DQB1*0605 0.006 DRB1*0101 0.056 DRB1*0301 0.068 DRB1*0401 0.019 DRB1*0402 0.031 DRB1*0403 0.019 DRB1*0404 0.019 DRB1*0405 0.006 DRB1*0407 0.006 DRB1*0408 0.006 DRB1*07 0.025 DRB1*0801 0.012 DRB1*1001 0.006 DRB1*1101 0.094 DRB1*1103 0.019 DRB1*1104 0.18 DRB1*1301 0.061 DRB1*1302 0.044 DRB1*1303 0.006 DRB1*1305 0.006 DRB1*1401 0.068 DRB1*1404 0.012 DRB1*1501 0.106 DRB1*1502 0.012 DRB1*1601 0.097 DRB1*1602 0.012 HLA haplotype Frequency (%) DRB1*0101-DQB1*0501 5.6 DRB1*0301-DRB3*0101-DQB1*0201 5 DRB1*0301-DRB3*02-DQB1*0201 1.8 DRB1*0401-DRB4*01-DQB1*0301 1.2 DRB1*0402-DRB4*01-DQB1*0302 3.1 DRB1*0403-DRB4*01-DQB1*0302 1.8 DRB1*0404-DRB4*01-DQB1*0302 1.8 DRB1*07-DRB4*01-DQB1*0202 1.2 DRB1*07-DRB4*01-DQB1*0303 1.2 DRB1*0801-DQB1*0402 1.2 DRB1*1101-DRB3*02-DQB1*0301 9.3 DRB1*1103-DRB3*02-DQB1*0301 1.8 DRB1*1104-DRB3*02-DQB1*0301 18.1 DRB1*1301-DRB3*0101-DQB1*0603 5.6 DRB1*1302-DRB3*0301-DQB1*0604 3.7 DRB1*1401-DRB3*02-DQB1*0503 6.2 DRB1*1404-DRB3*02-DQB1*0503 1.2
0198-8859/04/$–see front matter
1003
HLA haplotype Frequency (%) DRB1*1501-DRB5*0101-DQB1*0502 1.2 DRB1*1501-DRB5*0101-DQB1*0602 5 DRB1*1501-DRB5*0101-DQB1*0603 1.2 DRB1*1501-DRB5*0102-DQB1*0502 1.2 DRB1*1601-DRB5*02-DQB1*0502 10 DRB1*1602-DRB5*02-DQB1*0502 1.2
HLA-A, -B, -DQB1 and -DRB1 Alleles in a Population from Macedonia A. Arnaiz-Villena*, K. Dimitroski, A. Pacho, J. Moscoso, E. Gomez-Casado, C. Silvera-Redondo, P. Varela, M. Blagoevska, V. Zdravkovska and J. Martinez-Laso Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain and Institute of Blood Transfusion, Skopje, Republic of Macedonia E-mail: *[email protected] This population from Macedonia, Latitude 42N, Longitude 22E, consisted of 172 Caucasian individuals. The individuals were from a rural environment and they did not speak Albanian but Macedonian. They presently live at Skopje. HLA class I antigens were determined using a serological method and class II alleles using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 57, 118 –127, 2001. Human Immunology 65, 1003–1004 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*01 A*02 A*03 A*11 A*23 A*24 A*25 A*26 A*29 A*30 A*31 A*32 A*33
Gene frequency 0.137 0.256 0.119 0.076 0.035 0.163 0.017 0.067 0.012 0.017 0.020 0.032 0.012
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency A*68 0.038 B*07 0.064 B*08 0.067 B*13 0.015 B*14 0.009 B*15 0.018 B*18 0.166 B*27 0.041 B*35 0.148 B*37 0.020 B*38 0.052 B*39 0.017 B*40 0.035 B*41 0.012 B*44 0.078 B*45 0.003 B*49 0.015 B*50 0.006 B*51 0.148 B*52 0.023 B*53 0.003 B*55 0.026 B*56 0.003 B*57 0.020 B*58 0.009 B*78 0.003 DQB1*02 0.154 DQB1*0301 0.25 DQB1*0302 0.064 DQB1*0303 0.029 DQB1*0304 0.003 DQB1*0305 0.003 DQB1*0402 0.015 DQB1*0501 0.073 DQB1*0502 0.172 DQB1*0503 0.058 DQB1*0601 0.029 DQB1*0602 0.069 DQB1*0603 0.058 DQB1*0604 0.017 DQB1*0606 0.003 DQB1*0609 0.003 DRB1*0101 0.052 DRB1*0301 0.090 DRB1*0401 0.012 DRB1*0402 0.017 DRB1*0403 0.032 DRB1*0404 0.006 DRB1*0405 0.003 DRB1*0415 0.003 DRB1*0424 0.003 DRB1*0432 0.003 DRB1*0701 0.064 DRB1*0801 0.017 DRB1*0804 0.003 DRB1*090102 0.003 DRB1*1001 0.020
0198-8859/04/$–see front matter
Allele Gene frequency DRB1*0401 0.013 DRB1*0402 0.019 DRB1*0403 0.019 DRB1*0404 0.010 DRB1*0405 0.010 DRB1*0407 0.013 DRB1*0408 0.003 DRB1*0701 0.073 DRB1*0801 0.019 DRB1*0804 0.003 DRB1*0806 0.003 DRB1*090102 0.006 DRB1*1001 0.019 DRB1*1101 0.092 DRB1*1103 0.013 DRB1*1104 0.139 DRB1*1201 0.013 DRB1*1301 0.073 DRB1*1302 0.032 DRB1*1307 0.003 DRB1*1401 0.029 DRB1*1404 0.003 DRB1*1501 0.044 DRB1*1502 0.016 DRB1*1601 0.149 DRB1*1602 0.029
HLA-DQB1 and -DRB1 Allele Frequencies in a Population from Macedonia A. Hristova-Dimceva Institute of Blood Transfusion, Skopje, Republic of Macedonia E-mail: [email protected] This population from Macedonia, Latitude 42N Longitude 21E consisted of 80 Caucasian individuals from different regions of Macedonia. In the Republic of Macedonia the majority of the 2 million inhabitants are of Slavic origin, have the Christian Orthodox religion and speak the Macedonian language. Minority populations in Macedonia are formed by Albanians, Turks, Gypsies, Serbs and Vlachs. The individuals were drawn from an urban and rural environment and HLA alleles were determined using sequence specific primers. The results have previously been published in Tissue Antigens 55, 53–56, 2000. Human Immunology 65, 1002–1003 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency DQB1*0201 0.072 DQB1*0202 0.012 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency DQB1*0301 0.321 DQB1*0302 0.066 DQB1*0303 0.012 DQB1*0304 0.006 DQB1*0402 0.012 DQB1*0501 0.062 DQB1*0502 0.142 DQB1*0503 0.072 DQB1*0601 0.019 DQB1*0602 0.056 DQB1*0603 0.072 DQB1*0604 0.037 DQB1*0605 0.006 DRB1*0101 0.056 DRB1*0301 0.068 DRB1*0401 0.019 DRB1*0402 0.031 DRB1*0403 0.019 DRB1*0404 0.019 DRB1*0405 0.006 DRB1*0407 0.006 DRB1*0408 0.006 DRB1*07 0.025 DRB1*0801 0.012 DRB1*1001 0.006 DRB1*1101 0.094 DRB1*1103 0.019 DRB1*1104 0.18 DRB1*1301 0.061 DRB1*1302 0.044 DRB1*1303 0.006 DRB1*1305 0.006 DRB1*1401 0.068 DRB1*1404 0.012 DRB1*1501 0.106 DRB1*1502 0.012 DRB1*1601 0.097 DRB1*1602 0.012 HLA haplotype Frequency (%) DRB1*0101-DQB1*0501 5.6 DRB1*0301-DRB3*0101-DQB1*0201 5 DRB1*0301-DRB3*02-DQB1*0201 1.8 DRB1*0401-DRB4*01-DQB1*0301 1.2 DRB1*0402-DRB4*01-DQB1*0302 3.1 DRB1*0403-DRB4*01-DQB1*0302 1.8 DRB1*0404-DRB4*01-DQB1*0302 1.8 DRB1*07-DRB4*01-DQB1*0202 1.2 DRB1*07-DRB4*01-DQB1*0303 1.2 DRB1*0801-DQB1*0402 1.2 DRB1*1101-DRB3*02-DQB1*0301 9.3 DRB1*1103-DRB3*02-DQB1*0301 1.8 DRB1*1104-DRB3*02-DQB1*0301 18.1 DRB1*1301-DRB3*0101-DQB1*0603 5.6 DRB1*1302-DRB3*0301-DQB1*0604 3.7 DRB1*1401-DRB3*02-DQB1*0503 6.2 DRB1*1404-DRB3*02-DQB1*0503 1.2
0198-8859/04/$–see front matter
1003
HLA haplotype Frequency (%) DRB1*1501-DRB5*0101-DQB1*0502 1.2 DRB1*1501-DRB5*0101-DQB1*0602 5 DRB1*1501-DRB5*0101-DQB1*0603 1.2 DRB1*1501-DRB5*0102-DQB1*0502 1.2 DRB1*1601-DRB5*02-DQB1*0502 10 DRB1*1602-DRB5*02-DQB1*0502 1.2
HLA-A, -B, -DQB1 and -DRB1 Alleles in a Population from Macedonia A. Arnaiz-Villena*, K. Dimitroski, A. Pacho, J. Moscoso, E. Gomez-Casado, C. Silvera-Redondo, P. Varela, M. Blagoevska, V. Zdravkovska and J. Martinez-Laso Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain and Institute of Blood Transfusion, Skopje, Republic of Macedonia E-mail: *[email protected] This population from Macedonia, Latitude 42N, Longitude 22E, consisted of 172 Caucasian individuals. The individuals were from a rural environment and they did not speak Albanian but Macedonian. They presently live at Skopje. HLA class I antigens were determined using a serological method and class II alleles using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 57, 118 –127, 2001. Human Immunology 65, 1003–1004 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*01 A*02 A*03 A*11 A*23 A*24 A*25 A*26 A*29 A*30 A*31 A*32 A*33
Gene frequency 0.137 0.256 0.119 0.076 0.035 0.163 0.017 0.067 0.012 0.017 0.020 0.032 0.012
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency A*68 0.038 B*07 0.064 B*08 0.067 B*13 0.015 B*14 0.009 B*15 0.018 B*18 0.166 B*27 0.041 B*35 0.148 B*37 0.020 B*38 0.052 B*39 0.017 B*40 0.035 B*41 0.012 B*44 0.078 B*45 0.003 B*49 0.015 B*50 0.006 B*51 0.148 B*52 0.023 B*53 0.003 B*55 0.026 B*56 0.003 B*57 0.020 B*58 0.009 B*78 0.003 DQB1*02 0.154 DQB1*0301 0.25 DQB1*0302 0.064 DQB1*0303 0.029 DQB1*0304 0.003 DQB1*0305 0.003 DQB1*0402 0.015 DQB1*0501 0.073 DQB1*0502 0.172 DQB1*0503 0.058 DQB1*0601 0.029 DQB1*0602 0.069 DQB1*0603 0.058 DQB1*0604 0.017 DQB1*0606 0.003 DQB1*0609 0.003 DRB1*0101 0.052 DRB1*0301 0.090 DRB1*0401 0.012 DRB1*0402 0.017 DRB1*0403 0.032 DRB1*0404 0.006 DRB1*0405 0.003 DRB1*0415 0.003 DRB1*0424 0.003 DRB1*0432 0.003 DRB1*0701 0.064 DRB1*0801 0.017 DRB1*0804 0.003 DRB1*090102 0.003 DRB1*1001 0.020
0198-8859/04/$–see front matter