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HOME BLOOD PRESSURE SIGNIFICANTLY DECREASES THROUGHOUT THE FIRST YEAR AFTER RENAL DENERVATION
A1524 JACC March 17, 2015 Volume 65, Issue 10S
Prevention Home Blood Pressure Significantly Decreases Throughout the First Year After Renal Denervation Poster Contributions Poster Hall B1 Monday, March 16, 2015, 9:45 a.m.-10:30 a.m. Session Title: Renal Nerve Denervation Abstract Category: 22. Prevention: Hypertension Presentation Number: 1247-128 Authors: Martine Beeftink, Willemien Verloop, Rosa L. de Jager, Margreet F. Sanders, Michiel Voskuil, Peter J. Blankestijn, Wilko Spiering, UMC Utrecht, Utrecht, The Netherlands
Background: Self-blood pressure monitoring (SBPM) is more reliable than office blood pressure (BP) measurements and can be used to monitor BP over a long period of time. The effect of renal denervation (RDN) on SBPM has not been well-researched. In addition, there is still debate whether RDN has an immediate effect or whether BP changes can occur until months after the treatment. Therefore, we evaluated the course of highly standardized self-blood pressure measurements (SBPM) throughout the first year after renal denervation (RDN).
Methods: 69 patients that were treated with RDN for resistant hypertension or intolerance to medication received an automated BP monitor. SBPM was measured twice daily during one week every month. Measurements were automatically uploaded to a secure internet website and mean BP levels were calculated per month for each individual. Patients visited the outpatient clinic for physical examination and laboratory testing at 6 and 12 months.
Results: There was a significant linear decrease of -0.64mmHg per month (95% CI -0.99;-0.29, p =.001) for systolic BP and 0.32mmHg for diastolic BP (95% Ci -0.52;-0.13, p=.002). In multivariable analysis, this effect was not influenced by change in antihypertensive medication (p=0.375). Smokers tended to have a greater effect on SBPM compared to non-smokers (-0.78mmHg vs -0.38mmHg, p=0.52).
Conclusion: SBPM slightly but significantly decreases throughout the first year after renal denervation, independently of antihypertensive drug treatment.
Prevention Home Blood Pressure Significantly Decreases Throughout the First Year After Renal Denervation Poster Contributions Poster Hall B1 Monday, March 16, 2015, 9:45 a.m.-10:30 a.m. Session Title: Renal Nerve Denervation Abstract Category: 22. Prevention: Hypertension Presentation Number: 1247-128 Authors: Martine Beeftink, Willemien Verloop, Rosa L. de Jager, Margreet F. Sanders, Michiel Voskuil, Peter J. Blankestijn, Wilko Spiering, UMC Utrecht, Utrecht, The Netherlands
Background: Self-blood pressure monitoring (SBPM) is more reliable than office blood pressure (BP) measurements and can be used to monitor BP over a long period of time. The effect of renal denervation (RDN) on SBPM has not been well-researched. In addition, there is still debate whether RDN has an immediate effect or whether BP changes can occur until months after the treatment. Therefore, we evaluated the course of highly standardized self-blood pressure measurements (SBPM) throughout the first year after renal denervation (RDN).
Methods: 69 patients that were treated with RDN for resistant hypertension or intolerance to medication received an automated BP monitor. SBPM was measured twice daily during one week every month. Measurements were automatically uploaded to a secure internet website and mean BP levels were calculated per month for each individual. Patients visited the outpatient clinic for physical examination and laboratory testing at 6 and 12 months.
Results: There was a significant linear decrease of -0.64mmHg per month (95% CI -0.99;-0.29, p =.001) for systolic BP and 0.32mmHg for diastolic BP (95% Ci -0.52;-0.13, p=.002). In multivariable analysis, this effect was not influenced by change in antihypertensive medication (p=0.375). Smokers tended to have a greater effect on SBPM compared to non-smokers (-0.78mmHg vs -0.38mmHg, p=0.52).
Conclusion: SBPM slightly but significantly decreases throughout the first year after renal denervation, independently of antihypertensive drug treatment.