- Email: [email protected]
How to obtain and use chromoendoscopy dyes for surveillance colonoscopy in inflammatory bowel disease: a technical guide
Accepted Manuscript How to obtain and use chromoendoscopy dyes for surveillance colonoscopy: A technical guide Tonya Kaltenbach, MD, MAS, Amandeep K. Shergill, MD, MS, Michael B. Wallace, MD, MPH PII:
S0016-5107(17)32318-0
DOI:
10.1016/j.gie.2017.09.022
Reference:
YMGE 10754
To appear in:
Gastrointestinal Endoscopy
Received Date: 19 September 2017 Accepted Date: 22 September 2017
Please cite this article as: Kaltenbach T, Shergill AK, Wallace MB, How to obtain and use chromoendoscopy dyes for surveillance colonoscopy: A technical guide, Gastrointestinal Endoscopy (2017), doi: 10.1016/j.gie.2017.09.022. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
TITLE: How to obtain and use chromoendoscopy dyes for surveillance colonoscopy: A technical guide Authors: Tonya Kaltenbach MD, MAS*1, Amandeep K Shergill MD, MS1, Michael B Wallace, MD, MPH2
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Tonya Kaltenbach MD, MAS Associate Professor of Clinical Medicine, UCSF Division of Gastroenterology, Department of Medicine San Francisco Veterans Affairs Medical Center 4150 Clement St/ VA 111B GI Section San Francisco, CA, 94121 Tel: 415-221-4810 x24103 Email: [email protected]
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Corresponding Author:
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Affiliations: 1. San Francisco VA Medical Center, University of CA, San Francisco; San Francisco, CA 2. Mayo Clinic Jacksonville; Jacksonville, Florida
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Chromoendoscopy with targeted biopsies is the optimal surveillance colonoscopy modality in patients with inflammatory bowel disease (IBD). Targeted as compared to random biopsies and chromoendoscopy as compared to white light endoscopy show improved yield for dysplasia detection (Laine et al1). One of the main barriers to the implementation of chromoendoscopy in routine clinical practice has been the difficulty to obtain and use the dye (Sanduleanu et al2). We provide a summary figure (Figure 1) and table (Table 1) as a guide to facilitate this step.
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Figure 1. A, To prepare the dye, the indigo carmine (IC) or methylene blue (MB) solution is diluted with sterile water. B, Alternatively, the IC powder is mixed into sterile water. C, The IC or MB is reconstituted by gently swirling the sterile water bottle. D, the water bottle is connected to the water jet channel using the auxiliary foot pump. E, an example of the color achieved with dilution and reconstitution of the dye. F, The dye solution is sprayed onto the antigravity side of the colonic mucosa using the water jet channel in a circumferential motion while withdrawing the colonoscope.
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References
1. Laine L, Kaltenbach T, Barkun A, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastrointest Endosc 2015;81:489-501 e26.
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2. Sanduleanu S, Kaltenbach T, Barkun A, et al. A roadmap to the implementation of chromoendoscopy in inflammatory bowel disease colonoscopy surveillance practice. Gastrointest Endosc. 2016;83:213-22.
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Acronyms
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IBD: inflammatory bowel disease IC: indigo carmine MB: methylene blue
S0016-5107(17)32318-0
DOI:
10.1016/j.gie.2017.09.022
Reference:
YMGE 10754
To appear in:
Gastrointestinal Endoscopy
Received Date: 19 September 2017 Accepted Date: 22 September 2017
Please cite this article as: Kaltenbach T, Shergill AK, Wallace MB, How to obtain and use chromoendoscopy dyes for surveillance colonoscopy: A technical guide, Gastrointestinal Endoscopy (2017), doi: 10.1016/j.gie.2017.09.022. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
TITLE: How to obtain and use chromoendoscopy dyes for surveillance colonoscopy: A technical guide Authors: Tonya Kaltenbach MD, MAS*1, Amandeep K Shergill MD, MS1, Michael B Wallace, MD, MPH2
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Tonya Kaltenbach MD, MAS Associate Professor of Clinical Medicine, UCSF Division of Gastroenterology, Department of Medicine San Francisco Veterans Affairs Medical Center 4150 Clement St/ VA 111B GI Section San Francisco, CA, 94121 Tel: 415-221-4810 x24103 Email: [email protected]
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Corresponding Author:
RI PT
Affiliations: 1. San Francisco VA Medical Center, University of CA, San Francisco; San Francisco, CA 2. Mayo Clinic Jacksonville; Jacksonville, Florida
ACCEPTED MANUSCRIPT
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Chromoendoscopy with targeted biopsies is the optimal surveillance colonoscopy modality in patients with inflammatory bowel disease (IBD). Targeted as compared to random biopsies and chromoendoscopy as compared to white light endoscopy show improved yield for dysplasia detection (Laine et al1). One of the main barriers to the implementation of chromoendoscopy in routine clinical practice has been the difficulty to obtain and use the dye (Sanduleanu et al2). We provide a summary figure (Figure 1) and table (Table 1) as a guide to facilitate this step.
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Figure 1. A, To prepare the dye, the indigo carmine (IC) or methylene blue (MB) solution is diluted with sterile water. B, Alternatively, the IC powder is mixed into sterile water. C, The IC or MB is reconstituted by gently swirling the sterile water bottle. D, the water bottle is connected to the water jet channel using the auxiliary foot pump. E, an example of the color achieved with dilution and reconstitution of the dye. F, The dye solution is sprayed onto the antigravity side of the colonic mucosa using the water jet channel in a circumferential motion while withdrawing the colonoscope.
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References
1. Laine L, Kaltenbach T, Barkun A, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastrointest Endosc 2015;81:489-501 e26.
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2. Sanduleanu S, Kaltenbach T, Barkun A, et al. A roadmap to the implementation of chromoendoscopy in inflammatory bowel disease colonoscopy surveillance practice. Gastrointest Endosc. 2016;83:213-22.
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Acronyms
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IBD: inflammatory bowel disease IC: indigo carmine MB: methylene blue