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Image registration for adaptive radiotherapy
Physica Medica 29 (2013) e1–e46
Contents lists available at ScienceDirect
Physica Medica journal homepage: www.elsevier.com/locate/ejmp
Abstracts of the SFPM Annual Meeting 2013 SESSION: IMAGE GUIDED AND ADAPTIVE RADIOTHERAPY MODERATORS Sophie Chiavassa and Vincent Marchesi REFRESHER COURSE 1 IMAGE GUIDED RADIOTHERAPY, TODAY AND TOMORROW G. Delpon. Institut de Cancérologie de l’Ouest, Service de Physique Médicale, Nantes, France Abstract not available. http://dx.doi.org/10.1016/j.ejmp.2013.08.004
INVITED COMMUNICATION
2 IMAGE REGISTRATION FOR ADAPTIVE RADIOTHERAPY A. Simon. LTSI, Laboratoire Traitement du signal et de l’image, INSERM U1099, Université de Rennes 1, Rennes, France
for locally advanced head and neck cancer. During treatment, weekly scans with manual segmentation were performed for each patient. Replanning dose distributions were calculated on each CT image. Two cumulatives doses distributions (with and without replanning) were then reported on the initial scanner planning by elastic registration (demons registration methods with trilinear interpolation of the dose). Three doses distributions (initially planned, cumulative with weekly replanning and without weekly replanning) were finally compared. The risk of oral hyposialia (reduction of the salivary flow) was estimated by the NTCP model (n = 1, m = 0.4 and TD50 = 39.9 Gy) for each of the three dose distributions. Results: The mean decrease of salivary glands volume during treatment was 27% [7–42%]. At the time of the initial planning, the mean dose to the parotid glands was 30.9 Gy, it increased to 32.5 Gy after cumulative dose without replanning but could be reduced to 28.9 Gy because of the weekly replanning. The risk of oral hyposialia was: 28.8% on the initial planning, 32.6% after the cumulative dose without replanning and 24.3% after the cumulative dose with weekly replanning (given outcome for five patients in the immediate). Conclusions: The parotid glands are overdosed during treatment compared to initial planning. Adaptive radiotherapy enables to keep the dosimetric benefit of IMRT planned in the parotid glands. A randomized study starts to validate the clinical benefit of this adaptive strategy (ARTIX Study).
http://dx.doi.org/10.1016/j.ejmp.2013.08.006 Abstract not available. http://dx.doi.org/10.1016/j.ejmp.2013.08.005
ORAL COMMUNICATIONS
3 ADAPTATIVE RADIOTHERAPY IN HEAD AND NECK CANCERS O. Henry, A. Simon, J. Castelli, J.-P. Manens, C. Lafond, E. Chajon, G. Louvel, M. Nassef, R. de Crevoisier. Centre Eugène Marquis, Rennes, France Introduction: In head and neck cancers, intensity modulated radiation therapy enables to save significantly parotid glands. During the seven weeks treatment period, morphological changes are likely to degrade the initial dosimetric benefit. The objective of the study is to quantify the benefit of weekly dose replanning for the salivary glands. Materials and methods: The study includes eleven patients treated in IMRT with simultaneous integrated boost (70 Gy–63 Gy–56 Gy) http://dx.doi.org/10.1016/S1120-1797(13)00254-8
4 ACCURACY EVALUATION OF CATALYSTTM, A 3D SURFACE IMAGING DEVICE DESIGNED FOR SET UP GUIDANCE AND ON-LINE TARGET MONITORING FOR TOMOTHERAPY TREATMENTS M. Lambrecht, F. Kalhom, C. Malet, M. Ayadi. Centre Léon Berard, Lyon, France, C-RAD AB, Uppsala Sweden, Centre Léon Berard, Lyon, France Introduction: Highly conformal helical treatments require a daily MV image for patient repositioning. Additional dose related to MV image guidance is evaluated at 1 to 3cGy per fraction. Over the last years, non-irradiant optical imaging technics have been developed such as CatalystTM. This system designed for handling patient positioning and intra-fraction motion detection is based on principles of photogrammetry and optical triangulation. With knowledge of the surface movements, a volumetric deformable model is used to predict the influence on the actual target position. Our study aims to compare accuracy of CatalystTM system against MVCT one and to develop an efficient procedure for clinical routine.
Contents lists available at ScienceDirect
Physica Medica journal homepage: www.elsevier.com/locate/ejmp
Abstracts of the SFPM Annual Meeting 2013 SESSION: IMAGE GUIDED AND ADAPTIVE RADIOTHERAPY MODERATORS Sophie Chiavassa and Vincent Marchesi REFRESHER COURSE 1 IMAGE GUIDED RADIOTHERAPY, TODAY AND TOMORROW G. Delpon. Institut de Cancérologie de l’Ouest, Service de Physique Médicale, Nantes, France Abstract not available. http://dx.doi.org/10.1016/j.ejmp.2013.08.004
INVITED COMMUNICATION
2 IMAGE REGISTRATION FOR ADAPTIVE RADIOTHERAPY A. Simon. LTSI, Laboratoire Traitement du signal et de l’image, INSERM U1099, Université de Rennes 1, Rennes, France
for locally advanced head and neck cancer. During treatment, weekly scans with manual segmentation were performed for each patient. Replanning dose distributions were calculated on each CT image. Two cumulatives doses distributions (with and without replanning) were then reported on the initial scanner planning by elastic registration (demons registration methods with trilinear interpolation of the dose). Three doses distributions (initially planned, cumulative with weekly replanning and without weekly replanning) were finally compared. The risk of oral hyposialia (reduction of the salivary flow) was estimated by the NTCP model (n = 1, m = 0.4 and TD50 = 39.9 Gy) for each of the three dose distributions. Results: The mean decrease of salivary glands volume during treatment was 27% [7–42%]. At the time of the initial planning, the mean dose to the parotid glands was 30.9 Gy, it increased to 32.5 Gy after cumulative dose without replanning but could be reduced to 28.9 Gy because of the weekly replanning. The risk of oral hyposialia was: 28.8% on the initial planning, 32.6% after the cumulative dose without replanning and 24.3% after the cumulative dose with weekly replanning (given outcome for five patients in the immediate). Conclusions: The parotid glands are overdosed during treatment compared to initial planning. Adaptive radiotherapy enables to keep the dosimetric benefit of IMRT planned in the parotid glands. A randomized study starts to validate the clinical benefit of this adaptive strategy (ARTIX Study).
http://dx.doi.org/10.1016/j.ejmp.2013.08.006 Abstract not available. http://dx.doi.org/10.1016/j.ejmp.2013.08.005
ORAL COMMUNICATIONS
3 ADAPTATIVE RADIOTHERAPY IN HEAD AND NECK CANCERS O. Henry, A. Simon, J. Castelli, J.-P. Manens, C. Lafond, E. Chajon, G. Louvel, M. Nassef, R. de Crevoisier. Centre Eugène Marquis, Rennes, France Introduction: In head and neck cancers, intensity modulated radiation therapy enables to save significantly parotid glands. During the seven weeks treatment period, morphological changes are likely to degrade the initial dosimetric benefit. The objective of the study is to quantify the benefit of weekly dose replanning for the salivary glands. Materials and methods: The study includes eleven patients treated in IMRT with simultaneous integrated boost (70 Gy–63 Gy–56 Gy) http://dx.doi.org/10.1016/S1120-1797(13)00254-8
4 ACCURACY EVALUATION OF CATALYSTTM, A 3D SURFACE IMAGING DEVICE DESIGNED FOR SET UP GUIDANCE AND ON-LINE TARGET MONITORING FOR TOMOTHERAPY TREATMENTS M. Lambrecht, F. Kalhom, C. Malet, M. Ayadi. Centre Léon Berard, Lyon, France, C-RAD AB, Uppsala Sweden, Centre Léon Berard, Lyon, France Introduction: Highly conformal helical treatments require a daily MV image for patient repositioning. Additional dose related to MV image guidance is evaluated at 1 to 3cGy per fraction. Over the last years, non-irradiant optical imaging technics have been developed such as CatalystTM. This system designed for handling patient positioning and intra-fraction motion detection is based on principles of photogrammetry and optical triangulation. With knowledge of the surface movements, a volumetric deformable model is used to predict the influence on the actual target position. Our study aims to compare accuracy of CatalystTM system against MVCT one and to develop an efficient procedure for clinical routine.