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Immune depression and cancer
CLINICAL
IMMUNOLOGY
AND
IMMUNOPATHOLOGY
6, 123- 129 (1976)
BOOK REVIEWS The
Plasma
Edited by
FRANK
Proteins: Structure, Function, and Genetic W. PUTNAM. Academic Press. New York,
Control. Second Edition. Volume 1. 1975. 481 pp., $37.50.
When the first edition of “The Plasma Proteins” was published 15 years ago, it was immediately recognized as a major contribution to protein literature. For example, the Quarterly Review ofBiology commented. “This treatise. . .is likely to stand for a good many years to come as the most authoritative survey of the whole field of plasma proteins. . .it is indispensable for workers in this field.” Incorporating all of the many major developments that have occurred in the field in the last 15 years was thought by almost everyone to be an impossible task; however, the much needed second edition of “The Plasma Proteins” has been rewritten by a group of internationally eminent authors with Frank W. Putnam, Distinguished Professor of Molecular Biology and Zoology, Indiana University, as editor. This volume has been revised to incorporate current knowledge in a lucid and critical manner with descriptions of structure, function and genetic control of blood proteins, for example, chapters by C.-B. Laurel1 on Protease Inhibitors in Plasma, Karl Schmid on Alpha-l Acid Glycoprotein, Hans J. Mullet--Eberhard on The Complement System and M. D. Poulik on B2-Microglobulin. Of special interest is the first chapter by Dr. Putnam entitled, “Perspectives-Past, Present and Future.” Highly recommended. H. Immune Depression and Cancer. Edited by G. W. SISKIND, Grune & Stratton. Inc., New York, 197.5. 209 pp., $12.50.
HUGH
C. L.
Editor
FUDENBERG,
CHRISTIAN,
AND
S. D.
LITWIV.
Each year the Irwin Strasburger Memorial Medical Foundation brings together outstanding medical scientists to discuss current aspects of problems related to both immunology and cancer. The selection of the topic for 1975, Immune Depression and Cancer, was initiated by the increasing level of serious investigation concerned with manipulation of the immune response and its relationship to malignancies and medical practice. The selection of speakers represented attempted to touch on critical issues and highlights of the field rather than to survey all present knowledge, and this volume attests to the success of that effort. The topics and their authors include: Suppressor T cells: Classes of Activity, Richard K. Gershon; Suppressor T Cells in Immunodeficiency, Thomas A. Waldmann, S. Broder, M. Durm, M. Blackman, and B. Meade; Role of Suppressor Cells in the Pathogenesis of Autoimmunity in New Zealand Mice, Alfred D. Steinberg, M. E. Gershwin, N. L. Gerber, J. A. Hardin, D. Barthold, L. M. Parker, and T. M. Chused; Mechanisms of Immunological Tolerance, David H. 123 Copyright All rights
CJ 1976 by Academic Press. Inc. of reproduction in any form reserved
124
ROOK
KEVIEWS
Katz; Mechanism of Antibody Mediated Immune Suppression, Gregory W. Siskind; Rh Immune Suppression: Re-examined. William Q. Ascari and William Pollack; Natural Immunosuppressive Factors, Sidney R. Cooperband, A. H. Glasgow, and J. A. Mannick; B- and T-Cell Function in Malignant Lymphoma. Alan C. Aisenberg. An edited discussion, usually highly informative, follows each chapter. Highly recommended.
Laboratory GEORGE
Diagnosis of Immunologic
BRECHER.
Grune
& Stratton,
Inc..
Disorders. New
York,
Edited 1975.
by GIKIW 320
pp.*
N.
VV.~.
DMI~I.
P. SI I r~s.
$19.00.
This volume, a publication of a postgraduate course at the University of California, aims to relate current knowledge of diagnostic methods in humoral and cellular immunity, transfusion and transplantation, immediate and delayed hypersensitivity, and immunodiagnosis of cancer to the daily practice of laboratory medicine. Authorities in every immunologic field discuss not only their own areas of personal research interest but review the immunologic tests available in the laboratory and useful in patient diagnosis and care; the resultant text is a comprehensive guide the the evaluation of both the old and the many new tests in the field of laboratory diagnosis. Without texts such as this, the non-expert is usually left to follow either the most recent. as yet unconfirmed, publication or his own anecdotal experience in deciding which test to use for a given problem. This book helps laboratory medicine meet the multiple challenges of improving availability, precision, and accuracy of measurements of known medical importance; to assure their proper interpretations; to introduce new tests; and to assess their significance and utility in patient management. Highly recommended. H. H~.LH FLIL)E:NHEKC;,EJditot
The Antibody New
York,
Molecule.
1975.
542
pp..
Edited $34.50.
by
A. NISONOI~I.
J. E. Hot~,t~.
,\\I)
S. B. SWI~C..
Academic
Press.
Much of our knowledge on antibody (immunoglobulin) molecules has been derived in the past few years. Striking significance of the antibody molecule in the defense mechanism of the individual, and the availability of large quantities of pure homogeneous material in monoclonal gammopathies facilitated multiple biochemical and functional studies. Although a vast amount of data has been published in this area in the past three years, a review of our knowledge on this subject is long-past due. This synthesis has been accomplished in an elegant manner by Alfred Nisonoff and his co-workers in their recent book “The Antibody Molecule.”
IMMUNOLOGY
AND
IMMUNOPATHOLOGY
6, 123- 129 (1976)
BOOK REVIEWS The
Plasma
Edited by
FRANK
Proteins: Structure, Function, and Genetic W. PUTNAM. Academic Press. New York,
Control. Second Edition. Volume 1. 1975. 481 pp., $37.50.
When the first edition of “The Plasma Proteins” was published 15 years ago, it was immediately recognized as a major contribution to protein literature. For example, the Quarterly Review ofBiology commented. “This treatise. . .is likely to stand for a good many years to come as the most authoritative survey of the whole field of plasma proteins. . .it is indispensable for workers in this field.” Incorporating all of the many major developments that have occurred in the field in the last 15 years was thought by almost everyone to be an impossible task; however, the much needed second edition of “The Plasma Proteins” has been rewritten by a group of internationally eminent authors with Frank W. Putnam, Distinguished Professor of Molecular Biology and Zoology, Indiana University, as editor. This volume has been revised to incorporate current knowledge in a lucid and critical manner with descriptions of structure, function and genetic control of blood proteins, for example, chapters by C.-B. Laurel1 on Protease Inhibitors in Plasma, Karl Schmid on Alpha-l Acid Glycoprotein, Hans J. Mullet--Eberhard on The Complement System and M. D. Poulik on B2-Microglobulin. Of special interest is the first chapter by Dr. Putnam entitled, “Perspectives-Past, Present and Future.” Highly recommended. H. Immune Depression and Cancer. Edited by G. W. SISKIND, Grune & Stratton. Inc., New York, 197.5. 209 pp., $12.50.
HUGH
C. L.
Editor
FUDENBERG,
CHRISTIAN,
AND
S. D.
LITWIV.
Each year the Irwin Strasburger Memorial Medical Foundation brings together outstanding medical scientists to discuss current aspects of problems related to both immunology and cancer. The selection of the topic for 1975, Immune Depression and Cancer, was initiated by the increasing level of serious investigation concerned with manipulation of the immune response and its relationship to malignancies and medical practice. The selection of speakers represented attempted to touch on critical issues and highlights of the field rather than to survey all present knowledge, and this volume attests to the success of that effort. The topics and their authors include: Suppressor T cells: Classes of Activity, Richard K. Gershon; Suppressor T Cells in Immunodeficiency, Thomas A. Waldmann, S. Broder, M. Durm, M. Blackman, and B. Meade; Role of Suppressor Cells in the Pathogenesis of Autoimmunity in New Zealand Mice, Alfred D. Steinberg, M. E. Gershwin, N. L. Gerber, J. A. Hardin, D. Barthold, L. M. Parker, and T. M. Chused; Mechanisms of Immunological Tolerance, David H. 123 Copyright All rights
CJ 1976 by Academic Press. Inc. of reproduction in any form reserved
124
ROOK
KEVIEWS
Katz; Mechanism of Antibody Mediated Immune Suppression, Gregory W. Siskind; Rh Immune Suppression: Re-examined. William Q. Ascari and William Pollack; Natural Immunosuppressive Factors, Sidney R. Cooperband, A. H. Glasgow, and J. A. Mannick; B- and T-Cell Function in Malignant Lymphoma. Alan C. Aisenberg. An edited discussion, usually highly informative, follows each chapter. Highly recommended.
Laboratory GEORGE
Diagnosis of Immunologic
BRECHER.
Grune
& Stratton,
Inc..
Disorders. New
York,
Edited 1975.
by GIKIW 320
pp.*
N.
VV.~.
DMI~I.
P. SI I r~s.
$19.00.
This volume, a publication of a postgraduate course at the University of California, aims to relate current knowledge of diagnostic methods in humoral and cellular immunity, transfusion and transplantation, immediate and delayed hypersensitivity, and immunodiagnosis of cancer to the daily practice of laboratory medicine. Authorities in every immunologic field discuss not only their own areas of personal research interest but review the immunologic tests available in the laboratory and useful in patient diagnosis and care; the resultant text is a comprehensive guide the the evaluation of both the old and the many new tests in the field of laboratory diagnosis. Without texts such as this, the non-expert is usually left to follow either the most recent. as yet unconfirmed, publication or his own anecdotal experience in deciding which test to use for a given problem. This book helps laboratory medicine meet the multiple challenges of improving availability, precision, and accuracy of measurements of known medical importance; to assure their proper interpretations; to introduce new tests; and to assess their significance and utility in patient management. Highly recommended. H. H~.LH FLIL)E:NHEKC;,EJditot
The Antibody New
York,
Molecule.
1975.
542
pp..
Edited $34.50.
by
A. NISONOI~I.
J. E. Hot~,t~.
,\\I)
S. B. SWI~C..
Academic
Press.
Much of our knowledge on antibody (immunoglobulin) molecules has been derived in the past few years. Striking significance of the antibody molecule in the defense mechanism of the individual, and the availability of large quantities of pure homogeneous material in monoclonal gammopathies facilitated multiple biochemical and functional studies. Although a vast amount of data has been published in this area in the past three years, a review of our knowledge on this subject is long-past due. This synthesis has been accomplished in an elegant manner by Alfred Nisonoff and his co-workers in their recent book “The Antibody Molecule.”