Immunochemical methods in cell and molecular biology, (biological techniques series)

Immunochemical methods in cell and molecular biology, (biological techniques series)

J. steroidBiochem. Vol. 33, No. 6, pp. 1257-1258, 1989 0022-4731/89 $3.00 + 0.00 Pergamon Press plc Printed in Great Britain BOOK REVIEWS -uses o...

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J. steroidBiochem. Vol. 33, No. 6, pp. 1257-1258, 1989

0022-4731/89 $3.00 + 0.00

Pergamon Press plc

Printed in Great Britain

BOOK REVIEWS

-uses of polyclonal antisera; -production and use of monoclonal antibodies; -synthetic peptides: a new development in protein immunochemistry; -gel electrophoretic procedures for the analysis of antigen mixtures and the isolation of antigens; -immunization details; -bleeding procedures; -antiserum processing; -methods for testing and using antibodies; -immunohistochemical procedures.

The Molecular and Cellular Endocrinology of the Testis, (Serono Symposia Publications, Vol. 50). Edited by B. A. COOKEand R. M. SHARPE.Published March 1989 by Raven Press, New York. No. of pages: 352. ISBN: o-88167-418-4. USS 90.00 (May, 1989). This book contains the Proceedings of rhe 5th European Workshop on the Molecular and Cellular Endocrinology of the Testis, held in Brighton, England on 13-16 April 1988.

It includes the following main topics: -inhibin; -trophic hormone receptors, transducing systems and regulation of steroidogenesis; -factors controlling blood and lymph flow and hormone secretion; -the aetiology of Leydig cells; -male infertility and contraception; -toxic substances affecting spermatogenesis; -control of spermatogenesis; -paracrine and autocrine control mechanisms.

This book would be very useful for people working in research on biochemistry, biophysics, molecular biology, physiology and biology.

Steroid Receptors nod Disease, Cancer, Autoimmune, Bone, and Circulatory Disorders, Edited by P. J. SHERIDAN,K. BLUMand M. C. TRACHTENBERG. Published 1988 bv Dekker. New York. No. of pages: 608 ISBN: O-8247-7954-1. Price USS 125.00 (U.S.A. and Canada).

This volume has been written by eminent scientists and contains a complete and exhaustive bibliography. It would be very useful for endocrinologists, biochemists, biologists and research workers in the field of reproduction.

Horizons in Endocrinology, (Serono Symposia Publications, Vol. 52). Edited by M. MAGGIand C. A. JOHNSTON.Published March 1989 by Raven Press, New York. No. of pages: 376. ISBN: O-88167-419-2. US% 92.50 (May, 1989). With the progress in molecular biology, there has been an enormous expansion of endocrinology in different fields. This book contains the Proceedings of the First Biannual Meeting of”Endocrinology Under 35” held in Florence, Italy on 23-25 May 1988 and includes new aspects including growth factors I, II and III, molecular biology and endocrinology. The main topics covered are as follows: -growth factors; -molecular biology in endocrinology; -mechanism of signal transduction; -immunoendocrinology; -pulsatile hormone secretion; -advances in neuropeptides. This volume would be very useful for endocrinologists, general clinicians, gynecologists, and people working in reproduction, biology and molecular biology. Immunochemical Methods in Cell and Molecular Biology, (Biological Techniques Series). R. J. MAYERand J. H. WALKER.Published 1987 by Academic Press, New York. No. of pages: 326. ISBN: O-12-480855-7. Immunochemical techniques in molecular biology have become one of the most important methodologies for advance in this field. This book contains up-to-date information on many of these problems, in particular the use of polyclonal and monoclonal antibodies. The following main topics are included: -polyclonal -polyclonal

This book contains recent and new aspects in three areas of steroidal hormone action. First, the reevaluated subcellular distributions of sex steroid, thyroxin (T4), triiodothyronine (T,), and vitamin D,, receptors are presented and contrasted to the reported subcellular distribution of glucocorticoid receptors. Second, the functional significance of the different domains in the receptor proteins and the genes that code for them are elucidated. Third, the multiple disease states that involve steroid hormones and their receptors. The main topics covered are as follows: -theoretical models of steroidal action; -molecular and genetic aspects of steroid receptors; -identification of steroid receptors in “non-target” clinically relevant tissues; -steroids, steroid receptors, and disease. This book would be very useful for general clinicians, endocrinologists, biologists, biochemists, and people working in molecular biology and reproduction.

Cellular Factors in Development and DilferentiationEmbryos, Teratocarcinomas and Differentiated Tissues, (Progress in Clinical and Biological Research, Vol. 284). Edited by STEPHENE. HARRISand PER-ERIK MANSSON. Published 1988 by Alan R. Liss, New York. No. of pages: 266. ISBN: O-8451-5134-7. USS54.00. This book contains interesting problems which include the analysis of gene expression in differentiated tissues, factors that play an important role in oocyte maturation and fertilization, and use of transgenic mice to elucidate the basic mechanism of gene programming during development. A session on teratocarcinomas demonstrates how this system has given; and will continue to give, insight into basic biological questions, concerning cellular factors, both endogenous and exogenous, that play a role in development. The main topics considered by the authors are as follows: -models to study gene expression during differentiationsteroid hormones;

antiserum production; antiserum processing; 1257