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Immunologic Considerations in Chronic Sinusitis, Allergic Fungal Sinusitis, or Otitis Media
Wednesday, September 28, 2005 6:30 AM to 7:45 AM LACC Room 152 ⫹ Room 153ABC Foundation Annual Meeting Symposia (FAMS) •
Chronic Rhinosinusitis: Many Etiologies and Many Therapies
J David Osguthorpe, MD; Michael S Benninger, MD; James A Hadley, MD Charleston SC; Detroit MI; Rochester NY Chronic rhinosinusitis is an inflammatory disorder of the nose and paranasal sinuses that has been present for at least three months. It represents the final common pathway of a wide variety of diseases, and significantly impacts the quality
6:30 AM to 7:45 AM LACC Room 150ABC ⫹ Room 151 Foundation Annual Meeting Symposia (FAMS) •
Immunologic Considerations in Chronic Sinusitis, Allergic Fungal Sinusitis, or Otitis Media
Richard C Haydon, III, MD (moderator); David S Hurst, MD PhD; Scott M Graham, MD; Bradley F Marple, MD Lexington KY; Scarborough ME; Iowa City IA; Dallas TX This symposium will present current advancements in the understanding of our patient’s immune system response so as to help physicians tailor treatments for chronic upper
P166 Otolaryngology–Head and Neck Surgery
of life of those affected. Potential etiologies include the “classic” bacterial or fungal infection, or an osteitis, superantigen reaction or biofilm, as well as inhalant allergy or allergic fungal rhinosinusitis, mucociliary disorders, and the like. Recent studies have advocated two general histopathologic types of chronic rhinosinusitis, namely an eosinophilic and polypoid response, and a glandular hyperplasia and hypertrophic response. The miniseminar will present the known etiologies of chronic rhinosinusitis, the pathophysiologies involved, and current thinking on appropriate treatments for each, from surgery and/or anti-bacterial or anti-fungal agents to anti-inflammatory interventions such as steroids, leukotriene modifiers, macrolides, anti-IgE agents, and immune deviation strategies such as immunotherapy.
respiratory illness. We will address new immunologic concepts which help account for the chronic nature of sinusitis and otitis media. Discussion will address 1) Immune Dysfunction in Refractory Sinusitis, 2) Immunologic and Allergic Characteristics of Patients with AFS, and 3) Allergy as an Etiology of Chronic OME. These studies will show that an immunological work-up in patients with refractory sinusitis is indicated as they have a surprisingly high incidence of immune dysfunction, that AFS patients require allergy immunotherapy following thorough surgical debriedment, and that most OME patients have been found to be atopic and many respond to immunotherapy. The symposium will include a basic overview of immunologic considerations that make the host patient susceptible to these diseases, case presentations, and time for questions.
August 2005
Chronic Rhinosinusitis: Many Etiologies and Many Therapies
J David Osguthorpe, MD; Michael S Benninger, MD; James A Hadley, MD Charleston SC; Detroit MI; Rochester NY Chronic rhinosinusitis is an inflammatory disorder of the nose and paranasal sinuses that has been present for at least three months. It represents the final common pathway of a wide variety of diseases, and significantly impacts the quality
6:30 AM to 7:45 AM LACC Room 150ABC ⫹ Room 151 Foundation Annual Meeting Symposia (FAMS) •
Immunologic Considerations in Chronic Sinusitis, Allergic Fungal Sinusitis, or Otitis Media
Richard C Haydon, III, MD (moderator); David S Hurst, MD PhD; Scott M Graham, MD; Bradley F Marple, MD Lexington KY; Scarborough ME; Iowa City IA; Dallas TX This symposium will present current advancements in the understanding of our patient’s immune system response so as to help physicians tailor treatments for chronic upper
P166 Otolaryngology–Head and Neck Surgery
of life of those affected. Potential etiologies include the “classic” bacterial or fungal infection, or an osteitis, superantigen reaction or biofilm, as well as inhalant allergy or allergic fungal rhinosinusitis, mucociliary disorders, and the like. Recent studies have advocated two general histopathologic types of chronic rhinosinusitis, namely an eosinophilic and polypoid response, and a glandular hyperplasia and hypertrophic response. The miniseminar will present the known etiologies of chronic rhinosinusitis, the pathophysiologies involved, and current thinking on appropriate treatments for each, from surgery and/or anti-bacterial or anti-fungal agents to anti-inflammatory interventions such as steroids, leukotriene modifiers, macrolides, anti-IgE agents, and immune deviation strategies such as immunotherapy.
respiratory illness. We will address new immunologic concepts which help account for the chronic nature of sinusitis and otitis media. Discussion will address 1) Immune Dysfunction in Refractory Sinusitis, 2) Immunologic and Allergic Characteristics of Patients with AFS, and 3) Allergy as an Etiology of Chronic OME. These studies will show that an immunological work-up in patients with refractory sinusitis is indicated as they have a surprisingly high incidence of immune dysfunction, that AFS patients require allergy immunotherapy following thorough surgical debriedment, and that most OME patients have been found to be atopic and many respond to immunotherapy. The symposium will include a basic overview of immunologic considerations that make the host patient susceptible to these diseases, case presentations, and time for questions.
August 2005