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Immunopathogenetic aspects of disease induced by helminth parasites
Inrernalionol Journalfor Parasitology, Vol. 27. No. 12. p. 1023. I Y Y ! 10 1997 Australian Society for Parasitology. Published by Elsevier Saetm Ltd
BOOK REVZEW
IMMUNUPATHOGENETIC ASPOF IHSEASE INDUCED BY I3ELMlNTR-Z PARASmS Edited by D. 0. Freeman. Karger, Basel, Switzerland 1997. 235 pp., 37 figures and 5 tables. CHF142, DM170, US$123.50 for individuals, double for institutions. ISBN 3-8055-6400-7
This multi-author volume of Clinical Immunology (formerly Progress in Allergy) maintains the high standard of scholarship to which readers of the series are accustomed. Most chapters address the role of cytokines and T helper cells in immune responses to heiminth infections, drawing on animal models and clinical cases to help understand disease processes in humans. Topics covered include onchercerciasis, intestinal helminths, zoonotic and anthropophilic hookworms, toxocariasis, lymphatic filariasis, schistosomiasis, echinococcosis, and Taenia solium cysticercosis.Adverse tissuereactions to thesediverse infectionsdo not follow a commonpattern of immune function dysregulationnor cluster at one pole of the Thl/Th2 paradigm. Regulation of IgE responses is alsoreviewed.Comprehensiveaccountsare provided
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of severalzoonoses,and though not novel, the level of exposureof humansto their pets’parasitesis dramatic: StephenKayes citesstudieswhich report that 7-30% of children in developedcountries are seropositive to Toxocara canis, and over 300humancases of eosinophilicenteritisassociated with the dug hookworm Ancyclostoma canintm have beenreported in north-easternAustralia in the past 10years(Paul Prociv). The volume iswell indexedand wiI1be of interest to researchersof the immunopathologyof helminth infections. IAN COLDJTZ, CSIRO Division of Animal Praduction, PastoralResearc-h Laboratory. Armidale NW 2350, Australia
BOOK REVZEW
IMMUNUPATHOGENETIC ASPOF IHSEASE INDUCED BY I3ELMlNTR-Z PARASmS Edited by D. 0. Freeman. Karger, Basel, Switzerland 1997. 235 pp., 37 figures and 5 tables. CHF142, DM170, US$123.50 for individuals, double for institutions. ISBN 3-8055-6400-7
This multi-author volume of Clinical Immunology (formerly Progress in Allergy) maintains the high standard of scholarship to which readers of the series are accustomed. Most chapters address the role of cytokines and T helper cells in immune responses to heiminth infections, drawing on animal models and clinical cases to help understand disease processes in humans. Topics covered include onchercerciasis, intestinal helminths, zoonotic and anthropophilic hookworms, toxocariasis, lymphatic filariasis, schistosomiasis, echinococcosis, and Taenia solium cysticercosis.Adverse tissuereactions to thesediverse infectionsdo not follow a commonpattern of immune function dysregulationnor cluster at one pole of the Thl/Th2 paradigm. Regulation of IgE responses is alsoreviewed.Comprehensiveaccountsare provided
1623
of severalzoonoses,and though not novel, the level of exposureof humansto their pets’parasitesis dramatic: StephenKayes citesstudieswhich report that 7-30% of children in developedcountries are seropositive to Toxocara canis, and over 300humancases of eosinophilicenteritisassociated with the dug hookworm Ancyclostoma canintm have beenreported in north-easternAustralia in the past 10years(Paul Prociv). The volume iswell indexedand wiI1be of interest to researchersof the immunopathologyof helminth infections. IAN COLDJTZ, CSIRO Division of Animal Praduction, PastoralResearc-h Laboratory. Armidale NW 2350, Australia