IMPETIGO CONTAGIOSA

544 " XBD=2516 XBD=1472 XBD=1727 XBD=1937 XBD=2023 XBD=2208 XBD=2269 XBD=2305 XBD=2425 XHG=1353 XHG=1490 XHG=1774 XHG=1953 XHG=2041 XHG=2225 XHG=2285 XHG=2320 XHG=2438 YBD=225 YBD=226 YHG=198>cotton-wool. YHG=198>Exudate YHG=207>was YHG=199>collected YHG=207>on YHG=207>a YHG=198>sterile YHG=200>swab XBD=728 XHG=751 XBD=780 XHG=608 YBD=227 YHG=206>TABLE YHG=206>U

" XBD=2468 XBD=2517 XHG=2480 XBD=1428 XBD=1514 XBD=1771 XBD=1943 XBD=2000 XBD=2033 XBD=2141 XBD=2193 XBD=2398 XHG=1356 YBD=264 XHG=1443 XHG=1530 XHG=1782 XHG=1955 XHG=2012 XHG=2044 XHG=2153 XHG=2205 XHG=2408 YBD=272 YHG=245>on YBD=273 YBD=271 YHG=236>and YHG=245>was YHG=235>immediately YHG=236>cultured YHG=246>a YHG=237>plate YHG=236>of YHG=235>blood-agar YHG=237>and " XBD=2517 XBD=1422 XHG=2311 XBD=1482 XBD=1640 XBD=1768 XBD=2001 XBD=2131 XBD=2293 XBD=2348 XHG=2360 YBD=311 XHG=1357 XHG=1442 XHG=1496 XHG=1657 XHG=1786 XHG=2047 XHG=2149 YBD=312 YHG=274>of YBD=303 YBD=302 YHG=275>preparing YHG=284>one YHG=275>of YHG=275>gentian YHG=275>violet YHG=275>blood-agar. YHG=275>This YHG=274>method " XBD=2519 XBD=1419 XHG=2445 XBD=1525 XBD=1656 XBD=1757 XBD=1955 XBD=2027 XBD=2141 XBD=2267 XBD=2423 XHG=1357 YBD=341 XHG=1446 XHG=1553 XHG=1682 XHG=1785 XHG=1984 XHG=2054 XHG=2167 XHG=2292 YBD=343 YHG=322>were YBD=347 YBD=342 YHG=314>the YHG=314>skin YHG=314>could YHG=317>not, YHG=314>however, YHG=314>be YHG=313>used YHG=314>when YHG=312>vesicles

" XBD=2440 XBD=2519 XHG=2455 XBD=1509 XBD=1643 XBD=1699 XBD=1809 XBD=2006 XBD=2109 XBD=2163 XBD=2264 XBD=2370 XHG=1356 YBD=380 XHG=1530 XHG=1659 XHG=1715 XHG=1826 XHG=2037 XHG=2126 XHG=2181 XHG=2282 XHG=2386 YBD=390 YHG=352>skin YBD=381 YBD=389 YHG=356>present, ; YHG=354>owing YHG=355>to YHG=353>their YHG=353>fragility YHG=353>and YHG=353>in YHG=352>such YHG=360>cases YHG=352>the " XBD=2520 XBD=1430 XHG=2349 XBD=1597 XBD=1712 XBD=1894 XBD=2082 XBD=2154 XBD=2210 XBD=2325 XBD=2369 XHG=2393 YBD=427 XHG=1358 XHG=1455 XHG=1623 XHG=1738 XHG=1924 XHG=2108 XHG=2180 XHG=2237 YBD=420 YHG=390>pipette. YBD=424 YBD=428 YBD=419 YBD=418 YBD=417 YHG=401>was YHG=392>washed YHG=392>with YHG=394>acetone, YHG=392>dropped YHG=400>on YHG=390>it YHG=391>from YHG=398>a " XBD=2520 XBD=1491 XHG=2464 XBD=1598 XBD=1690 XBD=1888 XBD=1983 XBD=2027 XBD=2116 XBD=2304 XBD=2446 XHG=1358 YBD=465 XHG=1512 XHG=1618 XHG=1711 XHG=1908 XHG=2006 XHG=2048 XHG=2138 XHG=2322 YBD=459 YHG=430>and YBD=467 YBD=457 YHG=431>Vesicle YHG=431>fluid YHG=440>was YHG=430>aspirated YHG=430>into YHG=439>a YHG=430>fine YHG=429>capillary YHG=429>pipette " XBD=2520 XBD=1514 XHG=2394 XBD=1616 XBD=1731 XBD=1785 XBD=1920 XBD=2086 XBD=2188 XBD=2383 XHG=1359 YBD=496 XHG=1527 XHG=1629 XHG=1745 XHG=1798 XHG=1967 XHG=2099 XHG=2201 YBD=497 YHG=467>aerobicYHG=469>cultures YHG=479>were YHG=469>made YHG=478>as YHG=469>above. YHG=468>Plates YHG=477>were YHG=467>incubated

" " " " " " "

XBD=1863 XBD=1432 XBD=1501 XBD=1560 XBD=1681 XBD=1736 XBD=1812 XBD=1582 XBD=1698 XBD=1828 XBD=1947 XBD=2035 XBD=2193 XBD=2262 XBD=2345 XBD=2520 XBD=1488 XBD=1619 XBD=1713 XBD=1842 XBD=1900 XBD=2053 XBD=2286 XBD=2521 XBD=1437 XBD=1564 XBD=1704 XBD=1823 XBD=1876 XBD=2023 XBD=2189 XBD=2294 XBD=2442 XBD=2522 XBD=1551 XBD=1650 XBD=1928 XBD=2028 XBD=2241 XBD=1523 XBD=1611 XBD=1705 XBD=1864 XBD=2100 XBD=2170 XBD=2329 XBD=2391 XBD=2521 XBD=1453 XBD=1721 XBD=1833 XBD=2022 XBD=2136 XBD=2224 XBD=2262 XBD=2321 XBD=2430 XBD=2525

XHG=1826 XHG=1358 XHG=1447 XHG=1518 XHG=1574 XHG=1697 XHG=1754 XHG=1408 XHG=1600 XHG=1716 XHG=1846 XHG=1965 XHG=2054 XHG=2212 XHG=2282 XHG=2363 XHG=1359 XHG=1506 XHG=1635 XHG=1729 XHG=1859 XHG=1918 XHG=2070 XHG=2302 XHG=1359 XHG=1467 XHG=1591 XHG=1731 XHG=1852 XHG=1904 XHG=2053 XHG=2217 XHG=2320 XHG=2468 XHG=1359 XHG=1572 XHG=1672 XHG=1950 XHG=2050 XHG=1407 XHG=1545 XHG=1633 XHG=1726 XHG=1886 XHG=2124 XHG=2192 XHG=2350 XHG=2406 XHG=1357 XHG=1469 XHG=1736 XHG=1848 XHG=2073 XHG=2151 XHG=2240 XHG=2279 XHG=2331 XHG=2443

YBD=544 YBD=535 YBD=536 YBD=585 YBD=584 YBD=583 YBD=590 YBD=632 YBD=624 YBD=631 YBD=630 YBD=671 YBD=670 YBD=667 YBD=663 YBD=710 YBD=703 YBD=702 YBD=742 YBD=747 YBD=740 YBD=741 YBD=788 YBD=780 YBD=781

YHG=508>C. YHG=508>ally YHG=508>for YHG=508>24 YHG=508>hours YHG=510>at YHG=506>37° YHG=555>Cultures YHG=563>were YHG=556>made YHG=555>from YHG=554>230 YHG=554>lesions YHG=563>on YHG=553>130 YHG=553>patients. YHG=593>Every YHG=594>effort YHG=603>was YHG=595>made YHG=595>to YHG=594>isolate YHG=593>hsemolytic YHG=593>streptococci YHG=634>and YHG=642>even YHG=634>when YHG=634>only YHG=643>a YHG=634>single YHG=634>colony YHG=642>was YHG=632>found, YHG=633>the YHG=672>organism YHG=681>was YHG=672>investigated YHG=672>and YHG=672>recorded. YHG=712>From YHG=711>the YHG=711>230 YHG=712>lesions YHG=712>examined, YHG=711>85 YHG=711>strains YHG=710>of YHG=711>haemoYHG=750>lytic YHG=750>streptococci YHG=760>were YHG=752>isolated. YHG=750>All YHG=750>but YHG=750>5 YHG=750>of YHG=750>these YHG=759>were

" XBD=2521 XBD=1485 XHG=2383 XBD=1581 XBD=1695 XBD=1833 XBD=1893 XBD=1979 XBD=2079 XBD=2163 XBD=2367 XHG=1359 YBD=827 XHG=1504 XHG=1598 XHG=1712 XHG=1851 XHG=1910 XHG=1996 XHG=2097 XHG=2179 YBD=819 YHG=798>groups: YBD=820 YBD=826 YHG=790>tested YHG=790>and YHG=799>were YHG=787>found YHG=791>to YHG=791>fall YHG=791>into YHG=790>the YHG=789>following

" XBD=1295 XBD=177 XHG=858 XBD=324 XBD=494 XBD=696 XBD=831 XBD=938 XBD=1128 XBD=1181 XHG=95 XHG=205 XHG=353 XHG=520 XHG=725 XHG=964YBD=867 XHG=1157 XHG=1209 YBD=874 YBD=873 YBD=868 YBD=867 YBD=867 YBD=867 YBD=875 YHG=838>tive YHG=846>group YHG=846>among YHG=839>women), YHG=837>there YHG=837>still YHG=838>remains YHG=847>a YHG=829>50%

A

" XBD=2418 XBD=264 XBD=387 XBD=573 XBD=634 XBD=720 XBD=1004 XBD=1298 XHG=96 XHG=284 XHG=409 XHG=594 XHG=653 XHG=739 XHG=1022 YBD=907 YBD=907 YBD=915 YBD=907 YHG=877>increase YHG=877>since YHG=877>1930-32 YHG=878>in YHG=877>the YHG=876>degenerative YHG=876>heart-disease " |>" XBD=1527 XBD=1887 XBD=2260 XBD=1940 XBD=2508 XHG=1496 XHG=1868 XHG=1987 XHG=2303 XHG=2401 XHG=1937 XHG=2503 YBD=925 YBD=919 YBD=918 YBD=926 YBD=912 YHG=891>B YHG=892>0 YHG=890>Not YHG=891>..8 YHG=891>8 YHG=885>I A, B or C YHG=905>· " "" "" " " " " " " " " " " " " " " " " " " " "

XBD=1296XHG=868 XBD=200 XBD=357 XBD=460 XBD=572 XBD=721 XBD=785 XBD=852 XBD=996 XBD=1050 XBD=1184 XHG=96 XHG=216 XHG=369 XHG=476 XHG=590 XHG=742 XHG=801 XHG=1007 XHG=1063 XHG=1203 YBD=946 YBD=953 YBD=954 YBD=952 YBD=946 YBD=945 YBD=946 YHG=917>rates YHG=925>among YHG=925>men YHG=917>aged YHG=915>50-65, YHG=925>or YHG=925>an YHG=924>excess YHG=916>of YHG=916>about YHG=916>3300 XBD=1519 XBD=1636 XBD=1711 XBD=1801 XBD=2083 XBD=2234 XBD=2354 XBD=2523 XHG=1409 XHG=1549 XHG=1666 XHG=1734 XHG=1830 XHG=2110 XHG=2261 XHG=2382 YBD=981 YBD=982 YBD=974 YBD=983 YHG=943>Since YHG=943>86% YHG=943>of YHG=944>the YHG=943>streptococci YHG=943>which YHG=952>were YHG=945>grouped XBD=235 XHG=965 XBD=439 XBD=570 XBD=654 XBD=708 XBD=778 XBD=957 XBD=997 XBD=1163 XBD=1296 XHG=98 XHG=244 XHG=492 XHG=579 XHG=664 XHG=712 XHG=786 XHG=1006 XHG=1173 YBD=986 YBD=994 YBD=987 YBD=986 YBD=993 YBD=985 YBD=991 YBD=985 YHG=956>deaths YHG=956>annually. YHG=955>The YHG=956>size YHG=955>of YHG=956>the YHG=955>problem YHG=956>is YHG=955>similar, YHG=955>thereXBD=1547 XBD=1614 XBD=1758 XBD=1829 XBD=1922 XBD=2187 XBD=2298 XBD=2374 XBD=2408 XBD=2526 XHG=1360 XHG=1571 XHG=1638 XHG=1783 XHG=1855 XHG=1946 XHG=2210 XHG=2311 XHG=2389 XHG=2422 YBD=1021 YBD=1019 YBD=1022 YBD=1014 YBD=1013 YBD=1017 YHG=982>belonged YHG=983>to YHG=992>group YHG=984>A, YHG=984>assumption YHG=984>that YHG=984>the YHG=983>5 YHG=984>which XBD=190 XHG=495 XBD=262 XBD=400 XBD=472 XBD=723 XBD=1013 XBD=1298 XHG=97 XHG=219 XHG=289 XHG=428 XHG=751 XHG=1040 YBD=1032 YBD=1025 YBD=1026 YBD=1033 YBD=1031 YBD=1033 YHG=995>fore, YHG=995>to YHG=996>those YHG=995>of YHG=995>diphtheria, YHG=994>tuberculosis, YHG=995>prematurity XBD=1456 XBD=1552 XBD=1743 XBD=1863 XBD=1932 XBD=2070 XBD=2130 XBD=2225 XBD=2393 XBD=2452 XBD=2524 XHG=1360 XHG=1480 XHG=1574 XHG=1767 XHG=1887 XHG=1951 XHG=2095 XHG=2153 XHG=2246 XHG=2414 XHG=2471 YBD=1061 YBD=1062 YBD=1053 YBD=1054 YBD=1056 YHG=1032>were YHG=1023>not YHG=1024>grouped YHG=1033>were YHG=1024>of YHG=1032>group YHG=1025>A YHG=1032>can YHG=1023>involve YHG=1025>at YHG=1025>the XBD=176 XHG=743 XBD=286 XBD=508 XBD=649 XBD=727 XBD=932 XBD=1088 XBD=1299 XHG=99 XHG=191 XHG=301 XHG=524 XHG=665 XHG=947 XHG=1103 YBD=1065 YBD=1071 YBD=1065 YBD=1072 YBD=1072 YBD=1065 YHG=1035>and YHG=1034>road YHG=1034>accidents, YHG=1034>which YHG=1043>are YHG=1035>receiving YHG=1035>special YHG=1035>attention XBD=1463 XBD=1508 XBD=1623 XBD=1754 XBD=1888 XBD=1988 XBD=2066 XBD=2247 XBD=2315 XBD=2444 XBD=2526 XHG=1360 XHG=1484 XHG=1529 XHG=1644 XHG=1776 XHG=1912 XHG=2009 XHG=2087 XHG=2274 XHG=2341 XHG=2462 YBD=1098 YBD=1100 YBD=1093 YBD=1096 YHG=1063>most YHG=1071>a YHG=1071>very YHG=1063>small YHG=1072>error, YHG=1064>and YHG=1072>we YHG=1072>propose YHG=1064>to YHG=1063>make YHG=1064>this XBD=142 XHG=413 XBD=226 XBD=397 XBD=520 XHG=99 XHG=159 XHG=242 YBD=1104 YBD=1111 YBD=1104 YHG=1075>at YHG=1074>the YHG=1074>present YHG=1074>time. XBD=1612 XBD=1924 XBD=1985 XBD=2079 XBD=2215 XBD=2323 XBD=2385 XBD=2523 XHG=1360 XHG=1664 XHG=1942 XHG=1999 XHG=2097 XHG=2234 XHG=2339 XHG=2402 YBD=1133 YBD=1140 YBD=1132 YBD=1134 YHG=1102>assumption. YHG=1102>Streptococci YHG=1103>of YHG=1102>this YHG=1111>group YHG=1112>may YHG=1102>be YHG=1103>termed XBD=217 XHG=926 XBD=280 XBD=364 XBD=491 XBD=609 XBD=758 XBD=817 XBD=914 XBD=990 XBD=1106 XBD=1297 XHG=147 XHG=231 XHG=294 XHG=377 XHG=503 XHG=623 XHG=772 XHG=825 XHG=1003 XHG=1119 YBD=1151 YBD=1143 YBD=1142 YBD=1143 YBD=1148 YHG=1113>We YHG=1113>do YHG=1113>not YHG=1112>know YHG=1112>what YHG=1113>classes YHG=1113>of YHG=1121>men YHG=1122>are YHG=1113>most YHG=1112>affected, XBD=1629 XBD=1844 XBD=1944 XBD=2027 XBD=2178 XBD=2247 XBD=2337 XBD=2526 XHG=1361 XHG=1652 XHG=1895 XHG=1971 XHG=2054 XHG=2205 XHG=2272 XHG=2359 YBD=1179 YBD=1171 YBD=1172 YBD=1181 YHG=1141>Streptococcus YHG=1151>pyogenes. YHG=1142>So YHG=1151>we YHG=1142>arrive YHG=1142>at YHG=1142>the YHG=1142>following XBD=171 XHG=519 XBD=217 XBD=306 XBD=453 XBD=506 XBD=586 XBD=1006 XBD=1301 XHG=98 XHG=183 XHG=228 XHG=320 XHG=465 XHG=601YBD=1181 XHG=1022 YBD=1181 YBD=1189 YBD=1190 YHG=1151>but YHG=1152>it YHG=1147>was YHG=1151>shown YHG=1152>in YHG=1151>the YHG=1152>Registrar-General’s YHG=1152>Occupational XBD=1516XHG=832 XBD=1744 XBD=1804 XBD=1886 XBD=2092 XHG=1362 XHG=1533 XHG=1761 XHG=1817 XHG=1902 YBD=1211 YBD=1218 YHG=1180>simpler YHG=1181>statement YHG=1181>of YHG=1190>our YHG=1181>findings : 1930-32 XBD=298 XBD=456 XBD=528 XBD=824 XBD=942 XBD=1140 XBD=1300 XHG=98 XHG=307 XHG=468 XHG=714 XHG=955 XHG=1153 YBD=1228 YBD=1228 YBD=1220 YBD=1221 YBD=1229 YBD=1221 YHG=1188>Mortality YHG=1191>Report YHG=1191>for YHG=1191>4 YHG=1192>while YHG=1200>coronary YHG=1191>disease that XBD=175 XHG=804 XBD=339 XBD=526 XBD=645 XBD=783 XBD=909 XBD=1041 XBD=1234 XBD=1300 XHG=98 XHG=198 XHG=360 XHG=549 XHG=668 XHG=932 XHG=1063 XHG=1257 YBD=1260 YBD=1268 YBD=1267 YBD=1260 YBD=1261 YBD=1261 YBD=1261 YHG=1229>and YHG=1231>angina YHG=1230>pectoris YHG=1239>were YHG=1231>much YHG=1239>more YHG=1231>often YHG=1230>certified YHG=1240>as XBD=1563 XBD=1742 XBD=2325 XBD=2415 XHG=1495 XHG=1577 XHG=1767 XHG=2377 YBD=1272 YBD=1265 YHG=1236>Str. YHG=1245>pyogenes YHG=1258>.......... YHG=1238>74 XBD=229 XBD=288 XBD=417 XBD=572 XBD=673 XBD=727 XBD=986 XBD=1080 XBD=1300 XHG=99 XHG=244 XHG=298 XHG=431 XHG=584 XHG=686 XHG=1003 XHG=1094 YBD=1300 YBD=1299 YBD=1300 YBD=1307 YBD=1301 YBD=1308 YHG=1278>causes YHG=1269>of YHG=1269>death YHG=1277>among YHG=1279>men YHG=1270>in YHG=1271>professional YHG=1271>and YHG=1270>sedentary XBD=1609XHG=739 XBD=1824 XBD=2073 XBD=2327 XBD=2414 XHG=1497 XHG=1624 XHG=1840 XHG=2169 XHG=2380 YBD=1321 YBD=1312 YHG=1282>Other YHG=1282>hsemo]ytic YHG=1284>streptococci YHG=1306>.... YHG=1285>11 XBD=345 XHG=730 XBD=448 XBD=706 XBD=874 XBD=1002 XBD=1136 XBD=1302 XHG=98 XHG=371 XHG=471 XHG=897 XHG=1027 XHG=1159 YBD=1347 YBD=1339 YBD=1347 YBD=1341 YBD=1340 YBD=1340 YBD=1347 YHG=1309>occupations YHG=1308>and YHG=1310>myocardial YHG=1310>disease YHG=1319>more YHG=1310>often YHG=1318>among XBD=1703 XBD=1816 XBD=1987 XBD=2037 XBD=2210 XBD=2316 XBD=2391 XBD=2524 XHG=1411 XHG=1719 XHG=1834 XHG=1996 XHG=2045 XHG=2218 XHG=2325 XHG=2399 YBD=1383 YBD=1381 YBD=1374 YBD=1375 YBD=1377 YHG=1344>Staphylococci YHG=1352>were YHG=1344>present YHG=1344>in YHG=1344>cultures YHG=1345>from YHG=1344>216 YHG=1344>lesions. XBD=186 XHG=756 XBD=255 XBD=438 XBD=727 XBD=823 XBD=1052 XBD=1300 XHG=97 XHG=212 XHG=280 XHG=467 XHG=852 XHG=1081 YBD=1378 YBD=1378 YBD=1387 YBD=1379 YBD=1380 YBD=1380 YHG=1356>men YHG=1348>in YHG=1348>manual YHG=1350>occupations, YHG=1350>the YHG=1349>combined YHG=1349>death-rate XBD=1418 XBD=1546 XBD=1641 XBD=1818 XBD=1914 XBD=2036 XBD=2181 XBD=2247 XBD=2318 XBD=2525 XHG=1365 XHG=1438 XHG=1570 XHG=1666 XHG=1846 XHG=1939 XHG=2059 XHG=2205 XHG=2270 XHG=2340 YBD=1415 YBD=1419 YBD=1413 YBD=1414 YBD=1422 YHG=1385>Of YHG=1384>these YHG=1384>216 YHG=1384>strains, YHG=1384>173 YHG=1393>were YHG=1384>found YHG=1384>to YHG=1384>be YHG=1385>coaguloseXBD=164 XHG=807 XBD=250 XBD=307 XBD=411 XBD=519 XBD=630 XBD=794 XBD=902 XBD=1033 XBD=1144 XBD=1301 XHG=98 XHG=179 XHG=264 XHG=321 XHG=425 XHG=534 XHG=646 XHG=916YBD=1418 XHG=1048 XHG=1160 YBD=1418 YBD=1426 YBD=1419 YBD=1419 YBD=1420 YBD=1427 YHG=1387>did YHG=1388>not YHG=1389>at YHG=1388>that YHG=1388>time YHG=1397>vary YHG=1389>greatly YHG=1389>with YHG=1390>social YHG=1389>class YHG=1398>among XBD=1529XHG=886 XBD=1628 XBD=1741 XBD=1950 XBD=2021 XBD=2189 XBD=2337 XBD=2570 XHG=1363 XHG=1551 XHG=1649 XHG=1762 XHG=1972 XHG=2042 XHG=2211 XHG=2358 YBD=1461 YBD=1453 YBD=1454 YBD=1462 YHG=1424>positive YHG=1424>and YHG=1433>may YHG=1423>therefore YHG=1424>be YHG=1424>termed YHG=1423>Staph. YHG=1433>pyogenes. XBD=197 XBD=279 XBD=560 XBD=691 XBD=746 XBD=875 XBD=927 XBD=1057 XBD=1207 XBD=1300 XHG=97 XHG=212 XHG=292 XHG=572 XHG=704 XHG=757 XHG=942 XHG=1069 XHG=1221 YBD=1463 YBD=1458 YBD=1459 YBD=1459 YBD=1459 YHG=1436>men, YHG=1427>the YHG=1427>standardised YHG=1428>ratios YHG=1429>at YHG=1429>35-65 YHG=1430>in YHG=1429>social YHG=1429>classes YHG=1428>I-V XBD=1476XHG=594 XBD=1542 XBD=1625 XBD=1860 XBD=1976 XBD=2068 XBD=2261 XBD=2400 XBD=2455 XBD=2526 XHG=1363 XHG=1497 XHG=1559 XHG=1646 XHG=1880 XHG=1997 XHG=2087 XHG=2283 XHG=2419 XHG=2473 YBD=1493 YBD=1500 YBD=1501 YBD=1494 YBD=1495 YHG=1464>Some YHG=1463>of YHG=1464>the YHG=1463>remainder YHG=1472>were YHG=1464>not YHG=1463>isolated, YHG=1464>owing YHG=1465>to YHG=1465>the XBD=211 XBD=310 XBD=413 XBD=493 XBD=572 XBD=675 XHG=98 XHG=228 XHG=332 XHG=434 XHG=513 YBD=1504 YBD=1503 YBD=1504 YBD=1498 YHG=1467>being YHG=1467>118, YHG=1468>106, YHG=1467>95, YHG=1468>95, YHG=1468>108. XBD=1541XHG=770 XBD=1602 XBD=1773 XBD=1834 XBD=1964 XBD=2184 XBD=2421 XBD=2525 XHG=1363 XHG=1559 XHG=1618 XHG=1792 XHG=1854 XHG=1982 XHG=2203 XHG=2441 YBD=1532 YBD=1533 YBD=1540 YBD=1541 YBD=1534 YHG=1512>presence YHG=1503>of YHG=1503>proteus YHG=1512>or YHG=1503>other YHG=1503>spreading YHG=1503>organisms; YHG=1513>some XBD=226 XBD=404 XBD=462 XBD=550 XBD=655 XBD=700 XBD=755 XBD=842 XBD=1051 XBD=1106 XBD=1188 XBD=1301 XHG=146 XHG=239 XHG=418 XHG=472 XHG=563 XHG=668 XHG=714 XHG=856 XHG=1063 XHG=1120 XHG=1200 YBD=1536 YBD=1548 YBD=1538 YBD=1537 YBD=1537 YBD=1537 YBD=1538 YHG=1506>The YHG=1513>purpose YHG=1508>of YHG=1508>this YHG=1508>note YHG=1508>is YHG=1508>to YHG=1508>call YHG=1508>attention YHG=1508>to YHG=1508>the YHG=1507>facts XBD=1459 XBD=1742 XBD=1968 XBD=2126 XBD=2266 XBD=2433 XBD=2527 XHG=1362 XHG=1488 XHG=1770 XHG=1997 XHG=2154 XHG=2292 XHG=2464 YBD=1573 YBD=1572 YBD=1580 YBD=1579 YBD=1574 YHG=1552>were YHG=1543>accidentally YHG=1542>discarded YHG=1543>before YHG=1543>being YHG=1543>tested YHG=1544>and ; XBD=228 XHG=839 XBD=343 XBD=403 XBD=577 XBD=821 XBD=982 XBD=1074 XBD=1126 XBD=1235 XBD=1302 XHG=96 XHG=245 XHG=360 XHG=422 XHG=593 XHG=1001 XHG=1091 XHG=1142 XHG=1253 YBD=1577 YBD=1577 YBD=1584 YBD=1585 YBD=1583 YBD=1584 YBD=1577 YHG=1547>rather YHG=1547>than YHG=1548>to YHG=1548>suggest YHG=1547>underlying YHG=1556>causes, YHG=1547>but YHG=1548>it YHG=1556>may YHG=1547>be XBD=1468 XBD=1593 XBD=1744 XBD=1864 XBD=2046 XBD=2115 XBD=2287 XBD=2428 XBD=2526 XHG=1363 XHG=1496 XHG=1618 XHG=1769 XHG=1887 XHG=2071 XHG=2140 XHG=2313 XHG=2448 YBD=1612 YBD=1620 YBD=1613 YHG=1592>some YHG=1581>tested YHG=1582>with YHG=1582>batches YHG=1583>of YHG=1582>plasma YHG=1582>which YHG=1592>were XBD=294 XHG=826 XBD=349 XBD=478 XBD=580 XBD=680 XBD=737 XBD=813 XBD=914 XBD=1138 XBD=1192 XBD=1300 XHG=98 XHG=306 XHG=363 XHG=490 XHG=592 XHG=694 XHG=746 XHG=929 XHG=1150 XHG=1208 YBD=1624 YBD=1616 YBD=1617 YBD=1624 YBD=1616 YBD=1617 YBD=1616 YHG=1586>pertinent YHG=1587>to YHG=1587>recall YHG=1587>that YHG=1596>men YHG=1587>of YHG=1587>the YHG=1596>ages YHG=1586>concerned YHG=1586>in YHG=1586>1939

" " " "

XBD=2526XHG=833 XBD=1648 XBD=1807 XBD=1939 XBD=2136 XBD=2271 XBD=2349 XHG=1364 XHG=1683 XHG=1842 XHG=1974 XHG=2171 XHG=2307 XHG=2385 YBD=1699 YBD=1692 YBD=1691 YBD=1700 YHG=1662>staphylococci YHG=1661>which YHG=1671>were YHG=1660>isolated YHG=1662>from YHG=1662>30 YHG=1661>patients XBD=268 XBD=369 XBD=481 XBD=621 XBD=687 XBD=812 XBD=931 XBD=1047 XBD=1236 XBD=1301 XHG=102 XHG=291 XHG=391 XHG=502 XHG=643 XHG=705 XHG=952YBD=1696 XHG=1069 XHG=1258 YBD=1703 YBD=1695 YBD=1703YHG=1673>were YBD=1696 YHG=1666>1914-18 YHG=1666>and YHG=1666>that YHG=1674>many YHG=1666>of YHG=1659>them YHG=1665>then YHG=1666>exposed YHG=1666>to XBD=1515 XBD=1641 XBD=1744 XBD=2171 XBD=2398 XBD=2477 XBD=2526 XHG=1363 XHG=1549 XHG=1674 XHG=1779 XHG=2204 XHG=2443 XHG=2502 YBD=1739 YBD=1738 YBD=1731 YBD=1732 YHG=1701>yielded YHG=1701>only YHG=1710>one YHG=1701>coagulose-negative YHG=1701>organism. YHG=1701>It YHG=1701>is XBD=360 XHG=378 XBD=593 XHG=100 YBD=1736 YBD=1743 YHG=1704>considerable YHG=1705>hardships. XBD=1446 XHG=2450 XBD=1672 XBD=1969 XBD=2033 XBD=2205 XBD=2315 XBD=2431 XBD=2527 XHG=1364 YBD=1771 XHG=1470 XHG=1696 XHG=1992 XHG=2057 XHG=2228 XHG=2335 YBD=1776 YHG=1741>than YBD=1777 YBD=1770 YHG=1741>not, YHG=1741>therefore, YHG=1740>unreasonable YHG=1741>to YHG=1750>assume YHG=1741>that YHG=1750>more XBD=1452 XHG=2347 XBD=1517 XBD=1597 XBD=1899 XBD=2071 XBD=2184 XBD=2329 XBD=2512 XHG=1366 XHG=1472 XHG=1532 XHG=1616 XHG=1918 XHG=2088 XHG=2203 YBD=1811CONTAGIOSA YBD=1810 YBD=1817 YBD=1818 YHG=1780>95% YHG=1781>of YHG=1781>the YHG=1780>staphylococci YHG=1781>present YHG=1789>were YHG=1779>Staph. YHG=1789>pyogenes. IMPETIGO

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" XBD=1461 XBD=1611 XBD=1683 XBD=1761 XBD=2009 XBD=2139 XBD=2245 XBD=2317 XBD=2472 XHG=1362 XHG=1488 XHG=1641 XHG=1713 XHG=1791 XHG=2060 XHG=2168 XHG=2274 XHG=2346 XHG=2496 YBD=1651 YBD=1653 YBD=1652 YHG=1622>later YHG=1622>found YHG=1623>to YHG=1622>be YHG=1621>unreliable. YHG=1622>The YHG=1622>last YHG=1623>71 YHG=1622>strains YHG=1623>of " XBD=2534 XBD=194 XHG=844 XBD=391 XBD=480 XBD=591 XBD=657 XBD=721 XBD=821 XBD=890 XBD=1050 XBD=1138 XBD=1240 XBD=1306 XHG=98 XHG=217 XHG=412 XHG=502 XHG=612 XHG=675 XHG=743 XHG=912 XHG=1072 XHG=1160 XHG=1260 YBD=1656 YBD=1663 YBD=1656 YBD=1663 YBD=1656 YBD=1655 YHG=1635>were YHG=1626>between YHG=1626>the YHG=1635>ages YHG=1626>of YHG=1626>25 YHG=1626>and YHG=1626>44 YHG=1626>during YHG=1626>the YHG=1635>war YHG=1626>of

" XBD=2525 XBD=1524 XHG=2452 XBD=1584 XBD=1662 XBD=1788 XBD=1973 XBD=2121 XBD=2261 XBD=2440 XHG=1414 XHG=1540 XHG=1595 XHG=1678 XHG=1803 XHG=1988 XHG=2137 XHG=2274 YBD=1856 YHG=1828>nonYBD=1850 YBD=1849 YHG=1820>None YHG=1820>of YHG=1821>the YHG=1821>other YHG=1820>bacteria YHG=1820>found, YHG=1819>which YHG=1819>included ITS CAUSE AND

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TREATMENT XBD=2532 XHG=2413 XBD=1584 XBD=1879 XBD=2111 XBD=2384 XHG=1364 YBD=1894 XHG=1617 XHG=1913 XHG=2146 YBD=1898 YHG=1859>bacilli, YBD=1895 YBD=1897 YHG=1860>haemolytic YHG=1860>streptococci, YHG=1859>neisseriae, YHG=1859>diphtheroid XBD=1522 XBD=1621 XBD=1792 XBD=1968 XBD=2127 XBD=2326 XBD=2436 XBD=2532 XHG=1366 XHG=1544 XHG=1642 XHG=1814 XHG=1987 XHG=2149 XHG=2341 XHG=2452 YBD=1936 YHG=1899>than YBD=1930 YBD=1937 YBD=1935 YBD=1929 YHG=1900>proteus YHG=1900>and YHG=1899>aerobic YHG=1900>sporing YHG=1899>bacilli, YHG=1899>occurred YHG=1905>more JOSEPH W. BIGGER GEOFFREY A. HODGSON XBD=1637 XBD=1767 XBD=1968 XBD=2034 XBD=2174 XBD=2237 XBD=2335 XBD=2397 XBD=2526 XHG=1365 XHG=1688 XHG=1791 XHG=1990 XHG=2054 XHG=2196 XHG=2258 XHG=2356 YBD=1977 YBD=1976 YBD=1975 YBD=1969 YBD=1968 YHG=1938>infrequently. YHG=1939>The YHG=1949>presence YHG=1939>these, YHG=1948>as YHG=1938>also YHG=1938>of MRCPYHG=1939>hsemoM D OXFD DUBL, FRCPI, MD, SCDXHG=2414 XBD=1460 XBD=1735 XBD=1868 XBD=1987 XBD=2083 XBD=2296 XBD=2432 XBD=2527 XHG=1365 RAMC XHG=1484 XHG=1758 XHG=1890 XHG=2010 XHG=2105 XHG=2318 XHG=2451 YBD=2017 YHG=1987>were YBD=2009 YBD=2016 YBD=2008 YHG=1979>lytic YHG=1979>streptococci YHG=1979>other YHG=1979>than YHG=1978>Str. YHG=1987>pyogenes, YHG=1978>which MAJOR RAMC LIEUT.-COLONEL XBD=1464 XHG=2491 XBD=1567 XBD=1639 XBD=1831 XBD=1939 XBD=2014 XBD=2194 XBD=2372 XBD=2467 XBD=2532 XHG=1367 YBD=2047 XHG=1494 XHG=1598 XHG=1670 XHG=1862 XHG=1970 XHG=2041 XHG=2225 XHG=2400 YBD=2054 YHG=2017>be YBD=2048 YHG=2018>both YHG=2018>few YHG=2019>in YHG=2018>number YHG=2018>and YHG=2018>of YHG=2018>various YHG=2026>groups, YHG=2018>will XBD=238 XHG=837 XBD=372 XBD=576 XBD=818 XBD=907 XBD=1024 XBD=1198 XBD=1260 XBD=1306 XHG=150 XHG=258 XHG=391 XHG=597 XHG=927YBD=2082 XHG=1044 XHG=1218 XHG=1282 YBD=2090 YBD=2089 YBD=2082 YBD=2089 YBD=2081 YBD=2082 YHG=2053>THE YHG=2062>name YHG=2052>impetigo YHG=2052>contagiosa YHG=2052>has YHG=2052>been YHG=2052>applied, YHG=2052>to YHG=2061>a XBD=1610 XBD=1694 XBD=1791 XBD=2061 XBD=2181 XBD=2303 XBD=2421 XBD=2533 XHG=1368 XHG=1643 XHG=1724 XHG=1821 XHG=2092 XHG=2210 XHG=2331 XHG=2447 YBD=2094 YBD=2088 YBD=2087 YBD=2095 YBD=2086 YHG=2057>disregarded YHG=2067>on YHG=2058>the YHG=2058>assumption YHG=2058>that YHG=2057>they YHG=2066>were YHG=2066>mereXBD=253 XBD=317 XBD=420 XBD=615 XBD=735 XBD=890 XBD=1085 XBD=1307 XHG=102 XHG=273 XHG=332 XHG=440 XHG=666 XHG=910 XHG=1105 YBD=2123 YBD=2122 YBD=2129 YBD=2122 YBD=2121 YHG=2092>variety YHG=2092>of YHG=2092>skin YHG=2092>diseases. YHG=2092>We YHG=2092>accept YHG=2091>Sutton’s YHG=2091>definition XBD=1654XHG=756 XBD=1749 XBD=1908 XBD=1976 XBD=2085 XBD=2144 XBD=2315 XBD=2394 XBD=2528 XHG=1368 XHG=1673 XHG=1768 XHG=1927 XHG=1995 XHG=2102 XHG=2161 XHG=2330 XHG=2410 YBD=2128 YBD=2135 YBD=2134 YBD=2126 YBD=2127 YHG=2097>contaminants YHG=2097>and YHG=2097>played YHG=2107>no YHG=2097>part YHG=2097>in YHG=2096>causing YHG=2096>the YHG=2096>disease XBD=146 XHG=926 XBD=197 XBD=265 XBD=313 XBD=360 XBD=523 XBD=825 XBD=902 XBD=992 XBD=1241 XBD=1311 XHG=102 XHG=165 XHG=222 XHG=289 XHG=339 XHG=378 XHG=548 XHG=849 XHG=1017 XHG=1265 YBD=2161 YBD=2145 YBD=2169 YBD=2162 YBD=2161 YHG=2132>of YHG=2132>it YHG=2141>as YHG=2141>a YHG=2132>&dquo; YHG=2132>disease YHG=2131>characterised YHG=2131>by YHG=2131>the YHG=2140>occurrence YHG=2130>of XBD=1556 XBD=1666 XBD=1775 XBD=1890 XBD=2070 XBD=2138 XBD=2255 XHG=1369 XHG=1573 XHG=1683 XHG=1792 XHG=1910 XHG=2087 XHG=2156 YBD=2173 YBD=2167 YBD=2174 YBD=2166 YHG=2136>although YHG=2137>they YHG=2146>may YHG=2138>have YHG=2137>delayed YHG=2136>its YHG=2144>cure. XBD=264 XBD=517 XBD=688 XBD=780 XBD=908 XBD=1047 XBD=1134 XBD=1191 XBD=1307 XHG=102 XHG=278 XHG=532 XHG=704 XHG=922 XHG=1062 XHG=1148 XHG=1205 YBD=2202 YBD=2201 YBD=2208 YBD=2201 YHG=2172>discrete YHG=2171>thin-walled YHG=2171>vesicles YHG=2171>and YHG=2170>which YHG=2171>dry YHG=2171>to YHG=2170>form XBD=1498XHG=795 XBD=1678 XBD=1736 XBD=1817 XBD=1905 XBD=2090 XBD=2206 XBD=2289 XBD=2371 XBD=2528 XHG=1419YBD=2201 XHG=1514 XHG=1695 XHG=1752 XHG=1835 XHG=1925 XHG=2107 XHG=2222 XHG=2308 XHG=2387 YBD=2215YHG=2171>bullae YBD=2207 YBD=2206 YBD=2204 YBD=2213 YHG=2176>The YHG=2176>findings YHG=2177>in YHG=2176>the YHG=2176>230 YHG=2176>cultures YHG=2177>from YHG=2175>the YHG=2175>130 YHG=2175>patients XBD=298 XHG=859 XBD=532 XBD=697 XBD=817 XBD=946 XBD=1146 XBD=1306 XHG=102 XHG=345 XHG=575 XHG=739 XHG=980YBD=2240 XHG=1182 YBD=2249 YBD=2242 YBD=2241 YBD=2241 YBD=2241 YHG=2211>yellowish YHG=2211>adherent YHG=2211>crusts YHG=2210>and YHG=2210>heal YHG=2210>without YHG=2210>scar.&dquo; XBD=1434 XBD=1698 XBD=1752 XBD=1869 XBD=1898 XBD=1954 XBD=2090 XBD=2195 XBD=2280 XBD=2457 XBD=2528 XHG=1369 XHG=1446 XHG=1711 XHG=1765 XHG=1883 XHG=1912 XHG=1965 XHG=2104 XHG=2208 XHG=2294 XHG=2468 YBD=2247 YBD=2254 YBD=2246 YBD=2253 YBD=2245 YHG=2224>are YHG=2216>summarised YHG=2217>in YHG=2216>table YHG=2224>I YHG=2216>in YHG=2216>which YHG=2216>only YHG=2215>Str. YHG=2223>pyogenes YHG=2214>and XBD=315 XBD=576 XBD=816 XBD=917 XBD=1158 XBD=1308 XHG=104 XHG=340 XHG=601 XHG=942 XHG=1182 YBD=2282 YBD=2281 YBD=2280 YBD=2280 YBD=2280 YHG=2251>Infectious YHG=2250>eczematoid YHG=2243>dermatitis YHG=2251>and YHG=2250>dermatitis YHG=2250>which XBD=1653XHG=840 XBD=1823 XBD=1887 XBD=2031 XBD=2239 XBD=2315 XBD=2527 XHG=1369 XHG=1671 XHG=1837 XHG=1900 XHG=2044 XHG=2253 XHG=2329 YBD=2292 YBD=2294 YBD=2285 YBD=2286 YHG=2256>staphylococci YHG=2256>(almost YHG=2256>all YHG=2256>Staph. YHG=2256>pyogenes) YHG=2264>are YHG=2255>considered. XBD=172 XBD=435 XBD=820 XBD=999 XBD=1112 XBD=1196 XBD=1308 XHG=103 XHG=215 XHG=478 XHG=862 XHG=1041 XHG=1154 XHG=1238 YBD=2321 YBD=2328 YBD=2320 YBD=2319 YBD=2320 YHG=2291>has YHG=2291>undergone YHG=2290>impetiginisation YHG=2290>should YHG=2291>not YHG=2290>in YHG=2298>our XBD=2009 XHG=2034 XBD=2048 XHG=1892 YBD=2346 YBD=2347 YHG=2327>I YHG=2327>TABLE XBD=262 XHG=693 XBD=329 XBD=471 XBD=673 XBD=926 XBD=1024 XBD=1093 XBD=1309 XHG=105 XHG=280 XHG=349 XHG=489 XHG=946YBD=2366 XHG=1043 XHG=1114 YBD=2360 YBD=2368 YBD=2359 YBD=2360 YBD=2367 YHG=2330>opinion YHG=2330>be YHG=2330>called YHG=2330>impetigo YHG=2329>contagiosa, YHG=2329>and YHG=2338>no YHG=2329>examples XBD=1572 XBD=1634 XBD=1947 XBD=2040 XBD=2350 XBD=2534 XHG=1370 XHG=1589 XHG=1654 XHG=1964 XHG=2060 XHG=2368 YBD=2394 YBD=2393 YHG=2373>INCIDENCE YHG=2373>OF YHG=2373>STAPHYLOCOCCI YHG=2374>AND YHG=2372>STREPTOCOCCUS YHG=2372>PYOGENES. XBD=149 XHG=889 XBD=270 XBD=505 XBD=619 XBD=814 XBD=871 XBD=959 XBD=1102 XBD=1309 XHG=105 XHG=162 XHG=289 XHG=522 XHG=635 XHG=831 XHG=976YBD=2398 XHG=1120 YBD=2400 YBD=2399 YBD=2404 YBD=2406 YHG=2371>of YHG=2371>these YHG=2369>conditions YHG=2378>were YHG=2369>included YHG=2369>in YHG=2377>our YHG=2368>series, YHG=2368>although XBD=210 XBD=277 XBD=367 XBD=495 XBD=561 XBD=761 XBD=1005 XBD=1183 XBD=1307 XHG=105 XHG=233 XHG=296 XHG=389 XHG=516 XHG=577 XHG=784 XHG=1027 XHG=1207 YBD=2440 YBD=2438 YBD=2439 YBD=2446 YBD=2446 YBD=2438 YHG=2418>some YHG=2418>our YHG=2417>cases YHG=2409>of YHG=2408>impetigo YHG=2408>contagiosa YHG=2408>became XBD=2053 XHG=2493 XBD=2350 XBD=2515 XHG=1877 YBD=2463 XHG=2293 YBD=2448 YHG=2418>comYBD=2460 YHG=2427>PATIENTS YHG=2435>No. YHG=2434>% XBD=273 XBD=353 XBD=402 XBD=630 XBD=838 XBD=906 XBD=993 XBD=1106 XBD=1208 XBD=1308 XHG=104 XHG=298 XHG=378 XHG=426 XHG=652 XHG=862 XHG=926 XHG=1018 XHG=1130 XHG=1233 YBD=2478 YBD=2486 YBD=2477 YBD=2478 YBD=2477 YHG=2448>plicated YHG=2448>by YHG=2458>a YHG=2448>spreading YHG=2448>infection YHG=2448>of YHG=2448>the YHG=2447>skin YHG=2448>and XBD=1618 XHG=2474 XBD=1711 XBD=1757 XBD=1816 XBD=1970 XBD=2243 XBD=2346 XBD=2416 XBD=2526 XHG=1372 YBD=2499 XHG=1633 XHG=1724 XHG=1773 XHG=1830 XHG=2095 XHG=2312 XHG=2393 YBD=2504 YHG=2448>terYBD=2501 YBD=2500 YHG=2475>Staphylococci YHG=2476>only YHG=2476>in YHG=2476>all YHG=2476>cultures YHG=2494>.... YHG=2474>79 YHG=2493>.. YHG=2475>60.7

" XBD=279 XBD=346 XBD=604 XBD=856 XBD=953 XBD=1042 XBD=1145 XBD=1212 XHG=105 XHG=302 XHG=369 XHG=627 XHG=906 XHG=976 XHG=1065 XHG=1167 XHG=1230 YBD=2518 YBD=2517 YBD=2517 YBD=2517 YHG=2488>minated YHG=2497>as YHG=2487>eczematoid YHG=2487>dermatitis. YHG=2487>In YHG=2487>the YHG=2487>rest YHG=2487>of YHG=2487>this " XBD=1309 |>" XBD=1434 XBD=1600 XBD=1649 XBD=1904 XBD=1952 XBD=2010 XBD=2243 XBD=2345 XBD=2416 XBD=2534 XHG=1372 XHG=1447 XHG=1623 XHG=1664 XHG=1919 XHG=1966 XHG=2024 XHG=2311 XHG=2392 XHG=2474 YBD=2531 YBD=2532 YBD=2534 YBD=2530 YBD=2528 YBD=2529 YBD=2529 YHG=2507>Str. YHG=2512>pyogenes YHG=2508>+ YHG=2505>staphylococci YHG=2506>in YHG=2505>all YHG=2506>cultures YHG=2504>35 YHG=2523>.. YHG=2504>26-9 " XBD=1258 XBD=226 XBD=307 XBD=423 XBD=621 XBD=752 XBD=810 XBD=1008 XHG=106 XHG=241 XHG=323 XHG=437 XHG=636 XHG=825 XHG=1025 YBD=2564 YBD=2557 YBD=2556 YBD=2564 YBD=2564 YHG=2535>paper YHG=2527>the YHG=2528>term YHG=2527>impetigo YHG=2526>refers YHG=2527>to YHG=2526>impetigo YHG=2526>contagiosa. XBD=1433XHG=768 XBD=1598 XBD=1646 XBD=1899 XBD=1947 XBD=2048 XBD=2123 XBD=2195 XBD=2252 XHG=1371 XHG=1445 XHG=1620 XHG=1660 XHG=1912 XHG=1960 XHG=2063 XHG=2137 XHG=2209 YBD=2563 YBD=2562 YBD=2559 YBD=2560 YBD=2558 YHG=2536>Str. YHG=2541>pyogenes YHG=2538>+ YHG=2535>staphylococci YHG=2535>in YHG=2541>some YHG=2535>but YHG=2535>not YHG=2534>all " XBD=2243 XBD=2345 XBD=2415 XHG=1412 XHG=2312 XHG=2392 XHG=2491 YBD=2591 YBD=2588 YBD=2589 YHG=2565>cultures YHG=2564>10 YHG=2582>.. YHG=2563>7.7 " XBD=2526 XBD=236 XHG=835 XBD=371 XBD=534 XBD=615 XBD=766 XBD=826 XBD=885 XBD=1174 XBD=1232 XBD=1310 XHG=156 XHG=251 XHG=383 XHG=549 XHG=629 XHG=781 XHG=895YBD=2596 XHG=1188 XHG=1242 YBD=2604 YBD=2597 YBD=2604 YBD=2596YHG=2575>an YBD=2595 YHG=2566>The YHG=2575>paper YHG=2566>records YHG=2567>the YHG=2566>results YHG=2566>of YHG=2566>investigation YHG=2565>of YHG=2563>the

" XBD=2417 XBD=2528 XHG=2492 XBD=1432 XBD=1597 XBD=1688 XBD=1735 XBD=1794 XBD=2246 XHG=1370 YBD=2619 XHG=1445 XHG=1611 XHG=1702 XHG=1749 XHG=1806 XHG=2332 YBD=2623 YHG=2593>3.1 YBD=2620 YHG=2595>Str. YHG=2601>pyogenes YHG=2594>only YHG=2595>in YHG=2584>all YHG=2595>cultures YHG=2595>4 " XBD=368 XBD=441 XBD=536 XBD=671 XBD=743 XBD=949 XBD=1018 XBD=1197 XHG=107 XHG=397 XHG=469 XHG=566 XHG=699 XHG=976 XHG=1045 XHG=1226 YBD=2642 YBD=2635 YBD=2636 YBD=2643 YBD=2636 YBD=2636 YBD=2643 YHG=2605>bacteriology YHG=2606>of YHG=2606>130 YHG=2615>cases YHG=2607>of YHG=2606>impetigo YHG=2607>in YHG=2606>Service YHG=2614>per" XBD=1309 XBD=1432XHG=766 XBD=1597 XBD=1688 XBD=1735 XBD=1836 XBD=1911 XBD=1983 XBD=2245 XBD=2417 XBD=2527 XHG=2491 XHG=1370 XHG=1445 XHG=1611 XHG=1702 XHG=1748 XHG=1851 XHG=1925 XHG=1998 XHG=2331 YBD=2652 YBD=2653 YBD=2650 YBD=2649 YHG=2626>Str. YHG=2631>pyogenes YHG=2625>only YHG=2625>in YHG=2631>some YHG=2625>but YHG=2625>not YHG=2624>all YHG=2625>1 YHG=2623>0.8 ..’cultures.. " XBD=2527 XBD=241 XHG=861 XBD=362 XBD=472 XBD=566 XBD=646 XBD=841 XBD=938 XBD=1023 XBD=1252 XBD=1315 XBD=1505 XBD=1580 XBD=1745 XBD=1817 XBD=2246 XBD=2416 XHG=108 XHG=262 XHG=381 XHG=489 XHG=586 XHG=665 XHG=956YBD=2675 XHG=1040 XHG=1270 XHG=1371 XHG=1520 XHG=1594 XHG=1759 XHG=1830 XHG=2332 XHG=2491 YBD=2682 YBD=2683 YBD=2681 YBD=2676 YBD=2676 YBD=2675 YBD=2678 YBD=2682 YBD=2683 YBD=2679 YHG=2645>sonnel YHG=2644>(96% YHG=2654>men YHG=2645>4% YHG=2647>women), YHG=2646>and YHG=2646>the YHG=2645>treatment YHG=2645>of YHG=2655>Neither YHG=2655>Str. YHG=2660>pyogenes YHG=2661>nor YHG=2655>staphylococci YHG=2654>1.. YHG=2652>0.8

" XBD=175 XBD=376 XBD=437 XBD=567 XBD=671 XBD=711 XBD=806 XBD=888 XBD=1092 XBD=1215 XBD=1310 XHG=108 XHG=190 XHG=392 XHG=448 XHG=617 XHG=687 XHG=726 XHG=823 XHG=905 XHG=1107 XHG=1231 YBD=2713 YBD=2721 YBD=2714 YBD=2715 YBD=2715 YBD=2722 YBD=2715 YHG=2684>the YHG=2684>majority YHG=2684>of YHG=2684>them. YHG=2686>As YHG=2694>a YHG=2685>rule YHG=2685>the YHG=2685>vesicular YHG=2685>stage YHG=2685>had " XBD=2528 XBD=2245 XHG=2459 XBD=2346 XHG=1900 YBD=2739 XHG=2294 XHG=2393 YBD=2737 YHG=2695>100·0 YBD=2738 YHG=2714>Totals .. YHG=2713>130 YHG=2731>.. " XBD=2416 XBD=205 XHG=869 XBD=451 XBD=541 XBD=643 XBD=834 XBD=998 XBD=1102 XBD=1311 XHG=107 XHG=241 XHG=487 XHG=577 XHG=681 XHG=1035 XHG=1139 YBD=2760 YBD=2754 YBD=2753 YBD=2754 YBD=2762 YHG=2723>been YHG=2723>succeeded YHG=2724>by YHG=2724>the YHG=2724>crusted YHG=2724>before YHG=2724>the YHG=2724>patients " XBD=312 XBD=576 XBD=892 XBD=949 XBD=1002 XBD=1199 XBD=1312 XHG=107 XHG=334 XHG=627 XHG=915 XHG=970 XHG=1025 XHG=1222 YBD=2799 YBD=2793 YBD=2792 YBD=2793 YBD=2793 YBD=2792 YHG=2762>presented YHG=2762>themselves. YHG=2763>Nevertheless YHG=2763>it YHG=2763>is YHG=2763>believed YHG=2763>that |>" XBD=1617 XBD=1724 XBD=1789 XBD=1837 XBD=1915 XBD=2159 XBD=2253 XBD=2096 XHG=1372 XHG=1647 XHG=1753 XHG=1812 XHG=1853 XHG=2124 XHG=2188 XHG=1943 YBD=2799 YBD=2797 YBD=2800 YBD=2801 YHG=2771>Staphylococci YHG=2772>only YHG=2779>or YHG=2776>+ YHG=2771>Str. YHG=2772>in YHG=2776>any YHG=2778>pyogenes " XBD=160 XBD=274 XBD=397 XBD=459 XBD=654 XBD=715 XBD=881 XBD=1033 XHG=109 XHG=176 XHG=292 XHG=414 XHG=470 XHG=672 XHG=732 XHG=898 YBD=2830 YBD=2838 YBD=2832 YBD=2831 YBD=2832 YHG=2800>all YHG=2809>were YHG=2809>cases YHG=2801>of YHG=2800>impetigo YHG=2810>as YHG=2802>defined YHG=2801>above. |>" " XBD=1434 XBD=1638 XBD=1739 XBD=1792 XBD=1840 XBD=2254 XBD=2104 XBD=2158 XHG=1372 XHG=1464 XHG=1648 XHG=1756 XHG=1814 XHG=2189 XHG=1854 XHG=2118 YBD=2855 YBD=2856 YBD=2859 YBD=2858 YBD=2860 YBD=2856 YHG=2831>Str. YHG=2820>pyogenes YHG=2820>only YHG=2837>or YHG=2835>+ YHG=2837>any YHG=2820>staphylococci YHG=2820>in

.

culture

............

124

..

’954

"" XBD=1312 XBD=272 XBD=385 XBD=590 XBD=810 XBD=868 XBD=987 XBD=1138 XBD=1198 XHG=159 XHG=288 XHG=404 XHG=608 XHG=826 XHG=1004 XHG=1156 XHG=1216 YBD=2870 YBD=2869 YBD=2877 YBD=2871 YBD=2872 YBD=2871 YHG=2839>Cases YHG=2834>were YHG=2839>classified YHG=2841>according YHG=2842>to YHG=2841>their YHG=2842>extent YHG=2850>as YHG=2841>mild XBD=2244XHG=886 XBD=2416 XBD=2528 XHG=1413 XHG=2311 XHG=2474 YBD=2886 YBD=2887 YHG=2860>culture YHG=2859>50 YHG=2861>38’5 ..

" XBD=1035 XBD=1312XHG=772 XBD=184 XBD=374 XBD=487 XBD=590 XBD=742 XBD=905 XHG=114 XHG=202 XHG=397 XHG=512 XHG=614 XHG=957YBD=2916 XHG=1062 YBD=2915 YBD=2914 YBD=2908 YBD=2909 YBD=2910 YBD=2910 YHG=2880>(+), YHG=2878>medium YHG=2879>(++) YHG=2879>and YHG=2888>severe YHG=2881>(+++). YHG=2881>The YHG=2880>distribution " XBD=2505 XBD=211 XHG=780 XBD=788 XHG=109 YBD=2949 YBD=2926 YHG=2928>was YHG=2921>° : XBD=2063 XBD=2348 XHG=2482 XHG=1877 XHG=2290 YBD=2935 YBD=2948 YBD=2953 YHG=2914>CULTURES YHG=2922>No. YHG=2924>% |>" XBD=793 XBD=1017 XBD=1106 XBD=451 XHG=653 XHG=955 XHG=1030 XHG=337 YBD=2983 YBD=2983 YBD=2981 YBD=2984 YHG=2958>Number YHG=2960>Per YHG=2957>Extent YHG=2959>cent. " XBD=1620 XBD=2246 XBD=2348 XBD=2417 XBD=2534 XHG=1375 XHG=1634 XHG=2295 XHG=2394 XHG=2475 YBD=2991 YBD=2986 YBD=2988 YBD=2989 YHG=2961>Staphylococci YHG=2962>only YHG=2962>154 YHG=2980>.. YHG=2963>67.0 " XBD=1436 XBD=1601 XBD=1649 XBD=2247 XBD=2348 XBD=2417 XBD=2529 XHG=1374 XHG=1448 XHG=1623 XHG=1663 XHG=2314 XHG=2394 XHG=2475 YBD=3016 YBD=3021 YBD=3015 YBD=3017 YBD=3019 YHG=2991>Str. YHG=2997>pyogenes YHG=2995>+ YHG=2991>staphylococci YHG=2991>69 YHG=3010>.. YHG=2993>30,0 " XBD=441 XBD=607 XBD=746 XBD=917 XBD=1058 XHG=414 XHG=533 XHG=705 XHG=845 XHG=1016 YBD=3033 YBD=3030 YBD=3031 YBD=3032 YBD=3032 YHG=3009>+ YHG=3024>.... YHG=3003>26 YHG=3025>.... " XBD=2527 XBD=1436 XHG=2491 XBD=1601 XBD=1693 XBD=2247 XBD=2417 XHG=1374 YBD=3047 XHG=1449 XHG=1615 XHG=1735 XHG=2332 YBD=3049 YHG=3005>20 YBD=3050 YBD=3046 YHG=3021>Str. YHG=3027>pyogenes YHG=3022>only YHG=3039>..... YHG=3022>5 YHG=3023>2.1 " XBD=2417 XBD=441 XBD=607 XBD=746 XBD=917 XBD=1057 XHG=383 XHG=533 XHG=706 XHG=845 XHG=1016 YBD=3072 YBD=3070 YBD=3071 YBD=3071 YHG=3047>++ YHG=3042>86 YHG=3064>.... YHG=3044>66 " |>" XBD=1509 XBD=1583 XBD=2247 XBD=1820 XBD=2534 XHG=1374 XHG=1522 XHG=1833 XHG=2333 XHG=1597 XHG=2491 YBD=3075 YBD=3076 YBD=3079 YBD=3077 YBD=3079 YBD=3078 YHG=3050>Neither YHG=3051>Str. YHG=3040>staphylococci. YHG=3051>2.. YHG=3039>pyogenes nor , .. YHG=3052>0-9’

" XBD=1059 XBD=442 XHG=845 XBD=607 XBD=747 XBD=919 XHG=353 XHG=524 XHG=708 XHG=1019 YBD=3112 YBD=3114 YBD=3109 YBD=3110 YBD=3110 YHG=3087>+++ YHG=3082>18 YHG=3103>.... YHG=3083>14

" XBD=2526 XBD=2272 XHG=2458 XBD=2416 XHG=1902 YBD=3137 XHG=2393 YBD=3134 YHG=3111>100.0 YHG=3108>Totals .... YHG=3128>..

230

" XBD=866 XHG=558 YBD=3178 YHG=3154>BACTERIOLOGY

" XBD=2418 XBD=2529 XHG=2475 XBD=1620 XBD=1711 XBD=1760 XBD=1808 XBD=1884 XBD=2050 XBD=2248 XBD=2349 XHG=1375 YBD=3196 XHG=1633 XHG=1724 XHG=1783 XHG=1823 XHG=1897 XHG=2102 XHG=2296 XHG=2395 YBD=3197 YHG=3170>97.1} YBD=3195 YBD=3193 YBD=3194 YHG=3167>Staphylococci YHG=3169>only YHG=3175>or YHG=3172>+ YHG=3168>Str. YHG=3173>-pyogenes YHG=3187>.... YHG=3168>223 YHG=3187>.. " XBD=1436 XBD=1601 XBD=1692 XBD=1742 XBD=1790 XBD=2249 XBD=2418 XHG=2475 XHG=1375 XHG=1450 XHG=1616 XHG=1707 XHG=1765 XHG=1804 XHG=2317 YBD=3222 YBD=3227 YBD=3223 YBD=3225 YBD=3224 YBD=3226 YHG=3197>Str. YHG=3203>pyogenes YHG=3198>only YHG=3205>or YHG=3201>+ YHG=3197>staphylococci YHG=3198>74.. YHG=3200>32-2’ .... " XBD=2534 XBD=242 XHG=659 XBD=411 XBD=508 XBD=640 XBD=789 XBD=1030 XBD=1128 XBD=1189 XBD=1314 XHG=162 XHG=263 XHG=430 XHG=527 XHG=808YBD=3233 XHG=1051 XHG=1148 XHG=1208 YBD=3234 YBD=3238 YBD=3233 YBD=3234 YHG=3203>One YHG=3204>culture YHG=3212>was YHG=3203>made YHG=3202>before YHG=3202>treatment, YHG=3203>and YHG=3203>in YHG=3213>some

" " " " "

XBD=1314 XBD=217 XBD=320 XBD=491 XBD=575 XBD=630 XBD=747 XBD=927 XBD=1036 XBD=1162 XHG=113 XHG=231 XHG=374 XHG=503 XHG=589 XHG=643 XHG=761 XHG=940 XHG=1049 XHG=1176 YBD=3273 YBD=3272 YBD=3273 YBD=3272 YBD=3280 YHG=3251>cases YHG=3243>two. YHG=3242>Often YHG=3252>one YHG=3252>or YHG=3251>more YHG=3241>cultures YHG=3251>were YHG=3243>made YHG=3243>during XBD=1463 XBD=1553 XBD=1729 XBD=1785 XBD=1934 XBD=2112 XBD=2224 XBD=2325 XBD=2378 XBD=2528 XHG=1424 XHG=1475 XHG=1566 XHG=1743 XHG=1799 XHG=1947 XHG=2125 XHG=2237 XHG=2338 XHG=2390 YBD=3287 YBD=3293 YBD=3286 YBD=3294 YHG=3257>It YHG=3266>was YHG=3257>possible YHG=3257>to YHG=3257>obtain YHG=3257>cultures YHG=3256>from YHG=3257>only YHG=3257>10 YHG=3259>patients XBD=336 XHG=112 YBD=3312 YHG=3282>treatment. XBD=1416 XHG=2391 XBD=1517 XBD=1738 XBD=1880 XBD=1960 XBD=2058 XBD=2248 XBD=2359 XBD=2535 XHG=1374 YBD=3332 XHG=1450 XHG=1553 XHG=1774 XHG=1916 XHG=1990 XHG=2095 XHG=2298 YBD=3333 YHG=3297>patients YBD=3326 YBD=3325 YHG=3295>in YHG=3296>vesicular YHG=3296>stage YHG=3296>of YHG=3296>the YHG=3295>disease. YHG=3295>Six XBD=268 XBD=340 XBD=462 XBD=542 XBD=706 XBD=834 XBD=932 XBD=1108 XBD=1314 XHG=153 XHG=278 XHG=351 XHG=472 XHG=555 XHG=720 XHG=943 XHG=1119 YBD=3360 YBD=3365 YBD=3359 YBD=3358 YBD=3359 YHG=3331>When YHG=3333>the YHG=3333>lesion YHG=3341>was YHG=3331>crusted, YHG=3333>crusts YHG=3339>were YHG=3331>removed YHG=3331>mechanicXBD=1526XHG=843 XBD=1569 XBD=1731 XBD=1860 XBD=1990 XBD=2035 XBD=2216 XBD=2326 XBD=2416 XBD=2494 XHG=1375 XHG=1552 XHG=1595 XHG=1754 XHG=1883 XHG=2013 XHG=2059 XHG=2236 XHG=2347 XHG=2435 YBD=3372 YBD=3370 YBD=3363 YBD=3364 YBD=3365 YBD=3366 YHG=3334>yielded YHG=3335>1 YHG=3335>vesicle YHG=3335>each, YHG=3334>three YHG=3334>2 YHG=3333>vesicles YHG=3334>each YHG=3335>and YHG=3345>one

XBD=182 XHG=891 XBD=275 XBD=356 XBD=531 XBD=618 XBD=712 XBD=872 XBD=980 XBD=1118 XBD=1247 XBD=1317 XHG=109 XHG=202 XHG=293 XHG=378 XHG=552 XHG=639 XHG=730 XHG=1000 XHG=1140 XHG=1270 YBD=3404 YBD=3400 YBD=3399 YBD=3398 YBD=3398 YHG=3370>ally YHG=3371>and YHG=3371>the YHG=3371>selected YHG=3371>site YHG=3379>was YHG=3369>washed YHG=3370>with YHG=3370>sterile YHG=3370>saline YHG=3379>on " XBD=2527 XBD=1544 XBD=1674 XBD=1792 XBD=1971 XBD=2034 XBD=2204 XBD=2386 XBD=2467 XHG=1375 XHG=1595 XHG=1693 XHG=1811 XHG=1989 XHG=2048 XHG=2222 XHG=2402 XHG=2483 YBD=3402 YBD=3403 YBD=3405 YBD=3404 YHG=3373>vesicles. YHG=3373>The YHG=3374>total YHG=3373>number YHG=3373>of YHG=3373>vesicles YHG=3373>cultured YHG=3382>was YHG=3376>17.

" XBD=2336 XBD=2526 XBD=1424 XBD=1552 XBD=1650 XBD=1730 XBD=1837 XBD=1946 XBD=1984 XBD=2091 XBD=2250 XBD=2306 XHG=1376 YBD=3449 XHG=1436 XHG=1566 XHG=1663 XHG=1743 XHG=1851 XHG=1960 XHG=1996 XHG=2105 XHG=2264 XHG=2315 XHG=2349 YBD=3448 YBD=3442 YBD=3441 YHG=3413>In YHG=3420>every YHG=3421>case YHG=3412>the YHG=3412>fluid YHG=3421>gave YHG=3420>pure YHG=3412>culture YHG=3412>of YHG=3421>a 4. Registrar-General’s Decennial YHG=3413>coaguloseSupplement, 1931, Part IIa, p. 60. " XBD=2255 XBD=1540 XBD=1870 XBD=2032 XHG=2049 YBD=3488 XHG=1375 XHG=1557 XHG=1890 YBD=3489 YHG=3451>pyogenes). YHG=3451>positive YHG=3451>staphylococcus YHG=3451>(Staph.

5

545

" XBD=1307 XBD=259 XBD=326 XBD=456 XBD=651 XBD=774 XBD=915 XBD=1042 XBD=1164 XBD=1236 XHG=177 XHG=285 XHG=352 XHG=484 XHG=678 XHG=942 XHG=1070 XHG=1192 XHG=1262 YBD=241 YBD=240 YBD=238 YBD=239 YBD=238 YHG=209>Two YHG=218>or YHG=218>more YHG=209>cultures YHG=217>were YHG=209>from YHG=209>each YHG=209>of YHG=208>53 XBD=1441XHG=802 XBD=1644 XBD=1757 XBD=1885 XBD=1960 XBD=2097 XBD=2202 XBD=2267 XBD=2385 XBD=2566 XHG=1367YBD=239 XHG=1463 XHG=1666 XHG=1780 XHG=1906 XHG=1981 XHG=2114 XHG=2225 XHG=2289 XHG=2404 YBD=245YHG=209>made YBD=243 YBD=242 YBD=244 YBD=237 YHG=208>Str. YHG=215>pyogenes YHG=207>rises YHG=207>week YHG=207>by YHG=207>week, YHG=207>-just YHG=216>as YHG=208>with YHG=201>’wounds

" XBD=1445 XBD=1591 XHG=1367 XHG=1461 YBD=276 YHG=246>and YHG=247>burns. "|>|>" XBD=393 XBD=474 XBD=576 XBD=636 XBD=693 XBD=892 XBD=961 XBD=1141 XBD=1309 XBD=297 XHG=346 XHG=408 XHG=491 XHG=592 XHG=648 XHG=710 XHG=909 XHG=976 XHG=1158 XHG=133 YBD=280 YBD=278 YBD=285 YBD=277 YBD=277 YBD=284 YBD=289 YHG=248>In YHG=248>the YHG=257>case YHG=248>of YHG=248>42 YHG=248>patients, YHG=247>all YHG=248>cultures YHG=247>yielded YHG=248>patients.

" XBD=2464 XBD=2565XHG=886 XBD=1457 XBD=1561 XBD=1789 XBD=1904 XBD=1985 XBD=2090 XBD=2232 XBD=2301 XHG=1417 XHG=1482 XHG=1588 XHG=1815 XHG=1930 XHG=2012 XHG=2116 XHG=2259 XHG=2327 XHG=2492 YBD=322 YBD=314 YBD=315 YBD=316 YHG=285>It YHG=294>was YHG=285>suggested YHG=285>that YHG=294>we YHG=284>had YHG=284>failed YHG=285>to YHG=285>isolate YHG=285>Str. XBD=193 XBD=311 XBD=524 XBD=590 XBD=834 XBD=965 XBD=1152 XBD=1217 XBD=1308 XHG=131 XHG=213 XHG=334 XHG=549 XHG=614 XHG=988YBD=316 XHG=1176 XHG=1241 YBD=320 YBD=319 YBD=326 YBD=324 YBD=322 YHG=289>the YHG=296>saane YHG=287>organism YHG=295>or YHG=287>organisms. YHG=286>The YHG=286>findings YHG=286>in YHG=286>the XBD=174 XBD=301 XBD=373 XBD=529 XBD=769 XBD=968 XBD=1098 XHG=804 XHG=137 XHG=204 XHG=332 XHG=404 XHG=1002 XHG=1131 YBD=359 YBD=358 YBD=356 YBD=355 YBD=354 YHG=330>11 YHG=336>eases YHG=327>in YHG=326>which YHG=326>successive YHG=325>cultures YHG=333>gave YHG=324>different " XBD=1309 XBD=1660XHG=560 XBD=1779 XBD=1929 XBD=2103 XBD=2162 XBD=2238 XBD=2430 XBD=2485 XBD=2566 XHG=1561 XHG=1674 XHG=1791 XHG=1943 XHG=2118 XHG=2171 XHG=2252 XHG=2444 XHG=2499 YBD=361 YBD=353 YBD=362 YBD=354 YBD=355 YHG=324>from YHG=324>early YHG=324>lesions YHG=324>because YHG=323>of YHG=333>presence YHG=325>in YHG=324>the

pyogenes

" XBD=1811 XBD=1508 XBD=1623 XBD=1689 XHG=1369 XHG=1530 XHG=1645 XHG=1706 YBD=395 YBD=393 YHG=367>vesicle YHG=367>fluid YHG=367>of YHG=373>some XBD=256 XHG=675 XBD=333 XBD=481 XBD=538 XBD=657 XBD=718 XHG=133 XHG=271 XHG=350 XHG=496 XHG=554 YBD=399 YBD=396 YBD=395 YBD=394 YHG=367>results YHG=374>are YHG=366>shown YHG=365>in YHG=364>table YHG=371>11.

" XBD=1811 XBD=1576 XHG=1770 XBD=1756 XHG=1369 YBD=432 XHG=1587 YBD=433 YHG=403>to YHG=402>substance YHG=402>inimical " XBD=1209 XBD=1310XHG=743 XBD=234 XBD=456 XBD=690 XBD=951 XHG=132 XHG=276 XHG=508 XHG=1004 XHG=1262 YBD=458 YBD=455 YBD=454 YBD=453 YHG=436>TABLE YHG=434>II-CASES YHG=433>YIELDING YHG=433>DIFFERENT YHG=432>ORGANISMS YHG=433>AT " XBD=1438 XBD=1622 XBD=1701 XBD=1812 XHG=1370 XHG=1474 XHG=1656 XHG=1734 YBD=470 YBD=476 YBD=471 YHG=440>the YHG=441>growth YHG=442>of YHG=442>this " XBD=932 XBD=729 XHG=490 XHG=746 YBD=492 YBD=496 YHG=471>CULTURES YHG=471>SUBSEQUENT

" XBD=1811 XBD=1575 XHG=1691 XBD=1682 XHG=1371 YBD=510 XHG=1612 YBD=515 YHG=480>found YBD=509 YHG=479>organism. YHG=480>We |>" " XBD=1460 XBD=1560 XBD=1813 XBD=1685 XHG=1371 XHG=1492 XHG=1713 XHG=1591 YBD=547 YBD=548 YBD=548 YHG=517>that YHG=518>the YHG=519>from YHG=518>fluid

" XBD=1811 XBD=1449 XHG=1675 XBD=1643 XHG=1371 YBD=592 XHG=1485 YBD=586 YHG=558>which, YBD=587 YHG=557>two YHG=556>vesicles

" XBD=1775 XBD=1814 XHG=1790 XBD=1424 XBD=1604 XHG=1373 YBD=633 XHG=1445 XHG=1625 YBD=626 YHG=606>a YBD=625 YBD=631 YHG=604>on YHG=595>culture, YHG=596>yielded " XBD=1811 XBD=1466 XHG=1634 XBD=1625 XBD=1678 XHG=1682 YBD=673 XHG=1372 XHG=1476 YBD=671 YHG=636>of YBD=666 YHG=635>Staph. YHG=644>pure YHG=635>growth " XBD=1811 XBD=1553 XHG=1757 XBD=1649 XBD=1727 XHG=1370 YBD=705 XHG=1572 XHG=1678 YBD=711 YHG=676>inYBD=704 YHG=682>pyogenes YHG=675>had YHG=684>no

" XBD=1737 XBD=1813 XHG=1747 XBD=1545 XBD=1672 XHG=1372 YBD=744 XHG=1560 XHG=1686 YBD=751 YHG=715>the YHG=713>hibitory YHG=713>effect YHG=723>on " XBD=1814 XBD=1521 XHG=1583 XBD=1577 XBD=1659 XHG=1674 YBD=784 XHG=1372 XHG=1532 YBD=791 YHG=754>strains YBD=785 YHG=753>growth YHG=753>of YHG=754>two " XBD=1811 XBD=1418 XHG=1739 XBD=1514 XBD=1719 XHG=1372 YBD=831 XHG=1441 XHG=1540 YBD=823 YHG=793>isoYHG=793>of YHG=792>Str. YHG=802>pyogenes " XBD=1816 XBD=1478 XHG=1773 XBD=1610 XBD=1743 XHG=1373 YBD=862 YHG=832>of XHG=1511 XHG=1640 YHG=832>lated YHG=832>from YHG=842>cases

" XBD=1570 XHG=1373 YBD=908 YHG=871>impetigo. " XBD=1813 XBD=1523 XHG=1580 XHG=1423 YBD=941 YBD=940 YHG=911>relation YHG=911>The

" XBD=1812 XBD=1547 XHG=1679 XBD=1642 XHG=1373 YBD=993 XHG=1576 YBD=980 YHG=950>extent YHG=950>between YHG=951>the

" XBD=1811 XBD=1416 XHG=1744 XBD=1488 XBD=1645 XBD=1733 XHG=1371 YBD=1021 XHG=1423 XHG=1500 XHG=1657 YBD=1019 YHG=991>the YBD=1020 YHG=990>of YHG=990>the YHG=990>disease YHG=990>and

" XBD=1810 XBD=1442 XHG=1778 XBD=1649 XBD=1757 XHG=1368 YBD=1060 XHG=1468 XHG=1674 YBD=1059 YHG=1030>is YBD=1066 YHG=1029>Str. YHG=1038>pyogenes YHG=1030>rate " XBD=1748 XBD=1501 XHG=1694 XBD=1558 XBD=1678 XHG=1368 YBD=1098 YHG=1076>iv. XHG=1516 XHG=1574 YHG=1069>shown YHG=1068>in YHG=1069>table

" XBD=1813 XBD=1494 XHG=1415 XHG=1516 XHG=1769 YBD=1145 YBD=1137 YHG=1107>The YHG=1108>proportion YHG=1108>of "" XBD=1745 XBD=225 XBD=328 XBD=379 XBD=603 XBD=863 XBD=938 XBD=1142 XBD=1302 XHG=873 XHG=162 XHG=236 XHG=338 XHG=392 XHG=615 XHG=947 XHG=1153 YBD=1144 YBD=1146 YBD=1154 YBD=1156 YBD=1148 YBD=1157 YBD=1156YHG=1118>the YHG=1114>We YHG=1115>wish YHG=1117>to YHG=1117>emphasise YHG=1117>particularly YHG=1118>following YHG=1119>points: XBD=1504 XHG=1732 XBD=1566 XBD=1711 XBD=1804 XHG=1363 YBD=1177 YHG=1146>Str. XHG=1524 XHG=1587 YHG=1146>lesions YHG=1147>in YHG=1146>which "" XBD=1301 XBD=185 XBD=470 XBD=632 XBD=699 XBD=837 XBD=1031 XBD=1139 XHG=160 XHG=209 XHG=490 XHG=651 XHG=718 XHG=854 XHG=1051 XHG=1159 YBD=1193 YBD=1203 YBD=1196 YBD=1205 YBD=1205 YBD=1198 YBD=1207 YHG=1165>1. YHG=1163>Staphylococci YHG=1168>(almost YHG=1168>all YHG=1168>Staph. YHG=1170>pyogenes) YHG=1179>were YHG=1173>present XBD=1546 XBD=1658 XBD=1807 XHG=1364 XHG=1581 XHG=1686 YBD=1223 YBD=1216 YHG=1195>pyogenes YHG=1195>was YHG=1186>found "" XBD=1301 XBD=150 XBD=219 XBD=378 XBD=434 XBD=504 XBD=683 XBD=829 XBD=930 XBD=1090 XBD=1194 XHG=112 XHG=162 XHG=233 XHG=393 XHG=442 XHG=517 XHG=730 XHG=942 XHG=1103 XHG=1206 YBD=1233 YBD=1244 YBD=1235 YBD=1236 YBD=1245 YBD=1237 YBD=1237 YBD=1238 YHG=1204>in YHG=1204>223 YHG=1205>(97’0%) YHG=1207>of YHG=1207>the YHG=1208>cultures. YHG=1208>They YHG=1217>were YHG=1209>isolated YHG=1210>from YHG=1219>some XBD=1442XHG=840 XBD=1597 XBD=1656 XBD=1805 XHG=1363 XHG=1462 XHG=1614 XHG=1676 YBD=1256 YBD=1262 YBD=1255 YHG=1234>was YHG=1225>higher YHG=1226>in YHG=1225>extent" XBD=1299 XBD=152 XHG=834 XBD=211 XBD=266 XBD=336 XBD=508 XBD=626 XBD=734 XBD=816 XBD=981 XBD=1040 XBD=1115 XHG=112 XHG=166 XHG=225 XHG=275 XHG=353 XHG=524 XHG=643 XHG=754 XHG=1000YBD=1285 XHG=1052 XHG=1130 YBD=1272 YBD=1273 YBD=1274 YBD=1275 YBD=1276 YBD=1276YHG=1247>(95-4%) YBD=1277 YBD=1286 YHG=1253>.or YHG=1243>all YHG=1246>of YHG=1245>the YHG=1246>cultures YHG=1248>made YHG=1247>from YHG=1248>124 YHG=1249>of YHG=1249>the YHG=1249>patients. " XBD=1830 XBD=1443 XHG=1758 XBD=1610 XBD=1735 XHG=1361 YBD=1307 XHG=1470 XHG=1639 YBD=1294 YHG=1264>in YHG=1265>sive YHG=1265>lesions YHG=1264>than

"" ""

XBD=1298 XBD=185 XBD=271 XBD=451 XBD=539 XBD=697 XBD=751 XBD=813 XBD=978 XBD=1038 XBD=1113 XHG=158 XHG=207 XHG=286 XHG=467 XHG=556 XHG=715 XHG=772 XHG=832 XHG=998 XHG=1051 XHG=1131 YBD=1311 YBD=1314 YBD=1322 YBD=1324 YBD=1315 YBD=1316 YBD=1325 YBD=1316 YBD=1317 YBD=1318 YHG=1284>2. YHG=1282>Str. YHG=1294>pyogenes YHG=1296>was YHG=1290>present YHG=1287>in YHG=1288>74 YHG=1288>(32’2%) YHG=1288>of YHG=1289>the YHG=1289>cultures. XBD=1471 XBD=1606 XBD=1712 XBD=1844 XBD=2006 XBD=2123 XBD=2277 XBD=2391 XBD=2558 XHG=1360 XHG=1481 XHG=1616 XHG=1723 XHG=1895 XHG=2020 XHG=2138 XHG=2291 XHG=2404 YBD=1333 YBD=1341 YBD=1335 YBD=1334 YBD=1342 YHG=1304>those YHG=1303>which YHG=1312>were YHG=1303>small. YHG=1304>Since YHG=1304>large YHG=1304>lesions YHG=1313>were YHG=1305>usually XBD=150 XBD=228 XBD=388 XBD=492 XBD=602 XBD=720 XBD=774 XBD=847 XBD=1017 XBD=1134 XBD=1240 XBD=1298 XHG=119 XHG=162 XHG=241 XHG=401 XHG=508 XHG=618 XHG=735 XHG=863 XHG=1032 XHG=1149 XHG=1257 YBD=1351 YBD=1353 YBD=1354 YBD=1364 YBD=1355 YBD=1355 YBD=1356 YBD=1355 YBD=1357 YHG=1323>It YHG=1332>was YHG=1324>isolated YHG=1326>from YHG=1335>some YHG=1327>or YHG=1327>of YHG=1327>the YHG=1327>cultures YHG=1328>made YHG=1328>from YHG=1329>50 all XBD=1464XHG=786 XBD=1577 XBD=1700 XBD=1817 XBD=1911 XBD=2005 XBD=2124 XBD=2263 XBD=2328 XBD=2540 XHG=1359 XHG=1479 XHG=1590 XHG=1715 XHG=1833 XHG=1927 XHG=2019 XHG=2137 XHG=2277 XHG=2341 YBD=1378 YBD=1377 YBD=1373 YBD=1380 YHG=1343>older YHG=1343>than YHG=1343>small YHG=1351>ones, YHG=1343>this YHG=1352>was YHG=1343>what YHG=1343>might YHG=1343>be YHG=1344>expected.

" XBD=384 XBD=571 XHG=398 XBD=255 XBD=311 XHG=121 YBD=1401 XHG=272 XHG=321 YBD=1399 YHG=1366>patients. YBD=1393 YHG=1361>(38-5%) YHG=1365>of YHG=1365>the " XBD=2535 XBD=185 XHG=747 XBD=469 XBD=574 XBD=731 XBD=899 XBD=982 XBD=1162 XBD=1214 XBD=1297 XHG=916 XHG=157 XHG=208 XHG=485 XHG=590 XHG=997YBD=1434 XHG=1178 XHG=1235 YBD=1431 YBD=1441 YBD=1433 YBD=1442 YBD=1442 YBD=1433YHG=1406>Str. YBD=1435 YHG=1403>3. YHG=1402>Staphylococci YHG=1414>were YHG=1408>present YHG=1406>without YHG=1415>pyogenes YHG=1406>in YHG=1407>154 " XBD=1495 XBD=1816 XBD=1907 XBD=2217 XBD=2454 XHG=1377 XHG=1532 XHG=1862 XHG=1943 XHG=2259 XHG=2493 YBD=1448 YBD=1449 YBD=1450 YBD=1447 YHG=1428>TABLE YHG=1427>IV-INCIDENCE YHG=1427>OF YHG=1427>STREPTOCOCUS YHG=1427>PYOGENES YHG=1428>IN " XBD=254 XBD=310 XBD=383 XHG=108 XHG=271 XHG=321 YBD=1479 YBD=1472 YBD=1474 YHG=1442>-(67-0%) YHG=1444>of YHG=1444>the YHG=1444>cultures. " XBD=567 XBD=1852XHG=399 XBD=1914 XBD=2012 XBD=2074 XBD=2241 XHG=1667 XHG=1870 XHG=1936 XHG=2029 XHG=2088 YBD=1486 YBD=1487 YHG=1466>RELATION YHG=1466>TO YHG=1466>SIZE YHG=1466>OF YHG=1466>LESIONS

" " " "

5 XBD=1263XHG=748 XBD=185 XBD=271 XBD=460 XBD=557 XBD=722 XBD=900 XBD=1186 XHG=121 XHG=208 XHG=296 XHG=484 XHG=582 XHG=926YBD=1513 XHG=1210 YBD=1510 YBD=1511 YBD=1519 YBD=1521 YBD=1521 YBD=1512 YHG=1483>4. YHG=1482>Str. YHG=1492>pyogenes YHG=1494>was YHG=1487>present YHG=1485>without YHG=1484>staphylococci YHG=1484>in XBD=232 XHG=747 XBD=288 XBD=359 XBD=543 XBD=681 XBD=737 XBD=846 XBD=1016 XBD=1119 XBD=1197 XBD=1296 XHG=114 XHG=249 XHG=299 XHG=376 XHG=588 XHG=696 XHG=862YBD=1553 XHG=1030 XHG=1135 XHG=1212 YBD=1558 YBD=1550 YBD=1551 YBD=1552 YBD=1553 YBD=1552 YBD=1560 YHG=1521>(2-1%) YHG=1523>of YHG=1523>the YHG=1523>cultures. YHG=1524>Four YHG=1524>of YHG=1524>these YHG=1525>cultures YHG=1533>were YHG=1524>the YHG=1524>only XBD=191 XHG=866 XBD=310 XBD=423 XBD=531 XBD=592 XBD=632 XBD=820 XBD=939 XBD=1044 XBD=1201 XBD=1294 XHG=106 XHG=210 XHG=331 XHG=444 XHG=553 XHG=611 XHG=653 XHG=961YBD=1592 XHG=1065 XHG=1223 YBD=1590 YBD=1591 YBD=1600 YBD=1591 YBD=1593 YBD=1591 YHG=1570>YHG=1562>made YHG=1563>from YHG=1564>each YHG=1564>of YHG=1565>4 YHG=1563>patients. YHG=1564>The YHG=1563>fifth YHG=1563>culture YHG=1572>was ones XBD=208 XHG=903 XBD=315 XBD=355 XBD=514 XBD=648 XBD=794 XBD=884 XBD=992 XBD=1174 XBD=1293 XHG=109 XHG=226 XHG=334 XHG=374 XHG=534 XHG=667 XHG=813 XHG=1012 XHG=1193 YBD=1628 YBD=1638 YBD=1631 YBD=1630 YBD=1631 YBD=1630 YHG=1600>made YHG=1601>from YHG=1611>a YHG=1602>patient YHG=1603>whose YHG=1603>lesions YHG=1603>had YHG=1603>been YHG=1602>cultured YHG=1602>twice

" XBD=1293 XBD=311 XHG=692 XBD=431 XBD=525 XBD=677 XBD=833 XBD=1105 XBD=1213 XHG=116 XHG=357 XHG=447 XHG=542 XHG=846YBD=1678 XHG=1121 XHG=1231 YBD=1677 YBD=1669 YBD=1670 YBD=1678 YBD=1677YHG=1642>yielded YBD=1668 YHG=1637>previously. YHG=1641>The YHG=1641>first YHG=1642>culture YHG=1641>staphylococci YHG=1641>only, YHG=1641>the " XBD=1187 |>" XBD=231 XBD=323 XBD=517 XBD=575 XBD=864 XBD=964 XBD=1054 XBD=1291 XHG=110 XHG=258 XHG=351 XHG=549 XHG=607 XHG=893 XHG=992 XHG=1090 XHG=1223 YBD=1708 YBD=1716 YBD=1711 YBD=1718 YBD=1709 YBD=1709 YBD=1707 YBD=1708 YHG=1679>second YHG=1680>Str. YHG=1689>pyogenes YHG=1686>+ YHG=1681>staphylococci YHG=1681>and YHG=1681>the YHG=1680>third YHG=1680>Str.

" XBD=373 XBD=265 XHG=280 XHG=115 YBD=1756 YBD=1755 YHG=1720>only. YHG=1727>pyogenes |>" " XBD=183 XBD=448 XBD=535 XBD=810 XBD=914 XBD=1020 XBD=1177 XBD=1231 XBD=1293 XBD=268 XHG=155 XHG=283 XHG=463 XHG=551 XHG=825 XHG=931 XHG=1036 XHG=1194 XHG=1252 XHG=204 YBD=1794 YBD=1786 YBD=1796 YBD=1787 YBD=1787 YBD=1787 YBD=1796 YBD=1788 YBD=1786 YHG=1759>5. YHG=1768>pyogenes YHG=1760>and YHG=1759>stapJ;lylococci YHG=1768>were YHG=1759>both YHG=1759>Str. YHG=1761>present YHG=1759>in YHG=1759>69 " XBD=563 XBD=251 XHG=396 XBD=308 XBD=379 XHG=116 YBD=1826 XHG=268 XHG=318 YBD=1834 YHG=1798>cultures. YHG=1797>(30-0%) YHG=1799>of YHG=1798>the " XBD=1292 XBD=182 XHG=814 XBD=245 XBD=469 XBD=657 XBD=782 XBD=877 XBD=1004 XBD=1188 XHG=155 XHG=204 XHG=278 XHG=502 XHG=691 XHG=910YBD=1864 XHG=1038 XHG=1225 YBD=1866 YBD=1865 YBD=1865 YBD=1873 YBD=1864 YHG=1837>6. YHG=1836>In YHG=1838>successive YHG=1838>cultures YHG=1838>from YHG=1837>the YHG=1846>same YHG=1836>patient, YHG=1836>Str.

" XBD=262 XBD=360 XBD=490 XBD=637 XBD=692 XBD=903 XBD=986 XBD=1178 XHG=104 XHG=277 XHG=376 XHG=506 XHG=653 XHG=709 XHG=1004 XHG=1196 YBD=1911 YBD=1912 YBD=1913 YBD=1904 YBD=1912 YBD=1902 YHG=1884>_pyogenes YHG=1885>may YHG=1876>either YHG=1885>appear YHG=1886>or YHG=1877>disappear. YHG=1876>It YHG=1875>appeared YHG=1884>more " XBD=1292 XBD=2072XHG=950 XHG=1831 YBD=1922 YHG=1900>TREATMENT " XBD=766 |>" XBD=300 XBD=403 XBD=449 XBD=766 XHG=103 XHG=314 XHG=419 XHG=465 XHG=758 YBD=1951 YBD=1943 YBD=1952 YBD=1950 YHG=1915>commonly YHG=1916>than YHG=1916>it YHG=1915>disappeared. YHG=1944>e XBD=1483XHG=797 XBD=1781 XBD=1880 XBD=2102 XBD=2291 XBD=2355 XBD=2558 XHG=1403 XHG=1505 XHG=1801 XHG=1902 XHG=2124 XHG=2313 XHG=2379 YBD=1977 YBD=1984 YBD=1976 YBD=1985 YHG=1947>The YHG=1947>investigation YHG=1956>was YHG=1947>originally YHG=1946>planned YHG=1946>to YHG=1955>compare " XBD=1293 XBD=180 XBD=303 XBD=418 XBD=486 XBD=654 XBD=768 XBD=836 XBD=1017 XBD=1181 XHG=154 XHG=203 XHG=327 XHG=447 XHG=511 XHG=678 XHG=859 XHG=1042 XHG=1205 YBD=1982 YBD=1991 YBD=1990 YBD=1989 YHG=1956>7. YHG=1954>Fluid YHG=1955>17 YHG=1954>vesicles YHG=1955>from YHG=1955>10 YHG=1954>patients YHG=1953>yielded YHG=1961>pure " XBD=2558 XBD=1421 XBD=1571 XBD=1631 XBD=1797 XBD=1990 XBD=2049 XBD=2173 XBD=2500 XHG=1354 XHG=1438 XHG=1587 XHG=1643 XHG=1812 XHG=2006 XHG=2060 XHG=2187 XHG=2516 YBD=2017 YBD=2023 YBD=2016 YHG=1986>the YHG=1986>effects YHG=1986>of YHG=1986>various YHG=1987>methods YHG=1987>of YHG=1986>using YHG=1986>sulphonamides YHG=1987>in XBD=255 XHG=453 XBD=309 XBD=438 XBD=627 XHG=102 XHG=270 XHG=320 YBD=2022 YBD=2030 YBD=2029 YHG=1988>YHG=1994>of YHG=1993>Staph. YHG=2001>pyogenes. cultures " XBD=2555 XBD=1425 XBD=1558 XBD=1724 XBD=1784 XBD=1909 XBD=2025 XBD=2136 XBD=2277 XBD=2332 XBD=2413 XHG=1357 XHG=1441 XHG=1609 XHG=1739 XHG=1800 XHG=1923 XHG=2040 XHG=2150 XHG=2290 XHG=2347 XHG=2427 YBD=2054 YBD=2056 YBD=2055 YBD=2062 YHG=2026>100 YHG=2034>cases. YHG=2026>Later YHG=2026>30 YHG=2026>other YHG=2035>cases YHG=2035>were YHG=2025>added YHG=2026>to YHG=2026>the YHG=2026>series, XBD=104 XHG=831 XBD=180 XBD=254 XBD=560 XBD=795 XBD=918 XBD=1123 XBD=1197 XBD=1295 XHG=100 XHG=153 XHG=202 XHG=290 XHG=596 XHG=956YBD=2060 XHG=1159 XHG=1233 YBD=2051 YBD=2061 YBD=2069 YBD=2060 YBD=2059 YHG=2049>. YHG=2033>8. YHG=2032>No YHG=2032>morphological YHG=2032>differences YHG=2041>were YHG=2032>observed YHG=2031>in YHG=2031>the XBD=1428XHG=763 XBD=1502 XBD=1634 XBD=1876 XBD=1982 XBD=2233 XBD=2456 XBD=2557 XHG=1354 XHG=1459 XHG=1534 XHG=1665 XHG=1905 XHG=2015 XHG=2265 XHG=2489 YBD=2094 YBD=2096 YBD=2102 YBD=2101 YBD=2095 YHG=2064>but YHG=2074>as YHG=2065>their YHG=2065>treatment YHG=2075>was YHG=2065>essentially YHG=2064>different, YHG=2066>the " XBD=1293 XBD=232 XBD=282 XBD=393 XBD=470 XBD=641 XBD=748 XBD=876 XBD=1031 XBD=1112 XHG=100 XHG=246 XHG=298 XHG=408 XHG=485 XHG=658 XHG=890 XHG=1045 XHG=1126 YBD=2101 YBD=2100 YBD=2099 YBD=2107 YBD=2099 YBD=2106 YHG=2072>’-disease YHG=2072>in YHG=2081>cases YHG=2072>the YHG=2072>cultures YHG=2072>from YHG=2071>which YHG=2071>yielded YHG=2071>Str. YHG=2079>pyogenes " XBD=1493 XBD=1551 XBD=1633 XBD=1719 XBD=1843 XBD=1934 XBD=1997 XBD=2233 XBD=2344 XBD=2499 XHG=1354 XHG=1509 XHG=1566 XHG=1652 XHG=1738 XHG=1859 XHG=1950 XHG=2014 XHG=2249 XHG=2395 XHG=2516 YBD=2136 YBD=2135 YBD=2134 YHG=2104>results YHG=2104>in YHG=2104>the YHG=2105>100 YHG=2114>cases YHG=2105>will YHG=2105>be YHG=2104>considered YHG=2104>first. YHG=2104>Most YHG=2105>of " XBD=2561 XBD=174 XHG=710 XBD=222 XBD=336 XBD=388 XBD=518 XBD=619 XBD=696 XBD=787 XHG=100 XHG=188 XHG=236 XHG=350 XHG=403 XHG=533 XHG=635 YBD=2139 YBD=2147 YBD=2138 YHG=2112>and YHG=2111>those YHG=2111>in YHG=2110>which YHG=2111>they YHG=2111>did YHG=2113>not. " XBD=1462 XBD=1559 XBD=1749 XBD=1871 XBD=1988 XBD=2049 XBD=2274 XBD=2423 XBD=2557 XHG=1354 XHG=1479 XHG=1577 XHG=1768 XHG=1888 XHG=2006 XHG=2063 XHG=2292 XHG=2441 YBD=2173 YBD=2177 YBD=2175 YBD=2174 YBD=2181 YHG=2143>them YHG=2143>had YHG=2144>received YHG=2154>some YHG=2144>form YHG=2144>of YHG=2144>treatment YHG=2144>before YHG=2143>being " XBD=218 XBD=333 XBD=407 XBD=502 XBD=651 XBD=941 XBD=1004 XBD=1091 XBD=1186 XBD=1291 XHG=154 XHG=238 XHG=353 XHG=418 XHG=522 XHG=672 XHG=962 XHG=1025 XHG=1113 XHG=1206 YBD=2189 YBD=2188 YBD=2187 YBD=2196 YBD=2188 YBD=2187 YBD=2195 YHG=2158>We YHG=2167>were YHG=2159>at YHG=2158>first YHG=2158>rather YHG=2157>disappointed YHG=2158>at YHG=2158>the YHG=2157>low YHG=2166>pro" XBD=1445 XBD=1515 XBD=1589 XHG=1355 XHG=1461 XHG=1531 YBD=2212 YBD=2220 YBD=2213 YHG=2191>seen YHG=2182>by YHG=2191>us. |>" " XBD=254 XBD=312 XBD=490 XBD=629 XBD=795 XBD=1090 XBD=1294 XBD=883 XHG=100 XHG=268 XHG=323 XHG=504 XHG=644 XHG=899 XHG=1107 XHG=811 YBD=2235 YBD=2227 YBD=2226 YBD=2234 YBD=2234 YBD=2226 YBD=2233 YHG=2198>portion YHG=2198>of YHG=2197>cultures YHG=2197>which YHG=2197>yielded YHG=2206>pyogenes, YHG=2196>Str. YHG=2197>although " XBD=1578 XBD=1886 XBD=2138 XBD=2233 XBD=2322 XHG=1405 XHG=1594 XHG=1903 XHG=2154 XHG=2251 XHG=2340 YBD=2255 YBD=2260 YBD=2252 YBD=2251 YBD=2259 YHG=2222>Internal YHG=2223>sulphonamide YHG=2222>medication YHG=2231>was YHG=2223>not YHG=2222>employed. " XBD=2555 XBD=173 XHG=918 XBD=328 XBD=417 XBD=492 XBD=586 XBD=728 XBD=894 XBD=960 XBD=1094 XBD=1164 XBD=1294 XHG=113 XHG=193 XHG=352 XHG=442 XHG=516 XHG=606 XHG=751 XHG=985YBD=2265 XHG=1120 XHG=1184 YBD=2273 YBD=2264 YBD=2266 YBD=2265 YBD=2265 YBD=2266 YHG=2237>our YHG=2236>figures YHG=2245>are YHG=2245>on YHG=2236>the YHG=2236>whole YHG=2236>similar YHG=2236>to YHG=2236>those YHG=2236>of YHG=2236>other " XBD=1435 XBD=1763 XBD=1875 XBD=2043 XBD=2198 XBD=2292 XBD=2350 XBD=2557 XHG=1355 XHG=1451 XHG=1778 XHG=1891 XHG=2058 XHG=2214 XHG=2307 XHG=2367 YBD=2292 YBD=2298 YBD=2290 YBD=2291 YHG=2260>The YHG=2261>sulphonamides YHG=2271>were YHG=2261>applied YHG=2261>locally YHG=2261>and YHG=2261>to YHG=2261>facilitate " XBD=1294 XBD=263 XHG=920 XBD=396 XBD=623 XBD=678 XBD=814 XBD=897 XBD=987 XBD=1092 XBD=1204 XHG=113 XHG=285 XHG=419 XHG=646 XHG=701 XHG=836 XHG=1009 XHG=1114 XHG=1226 YBD=2304 YBD=2303 YBD=2305 YBD=2304 YBD=2305 YHG=2275>workers YHG=2275>when YHG=2274>allowance YHG=2274>is YHG=2274>made YHG=2274>for YHG=2275>the YHG=2274>fact YHG=2274>that YHG=2275>the " XBD=1455 XBD=1720 XBD=1764 XBD=1949 XBD=2076 XBD=2170 XBD=2295 XBD=2359 XHG=1354 XHG=1465 XHG=1739 XHG=1781 XHG=1966 XHG=2093 XHG=2189 XHG=2317 XHG=2378 YBD=2338 YBD=2337 YBD=2335 YBD=2330 YBD=2331 YHG=2299>their YHG=2301>application, YHG=2311>a YHG=2301>Lassar’s YHG=2300>paste YHG=2310>was YHG=2300>used, YHG=2309>as YHG=2300>follows " XBD=2553 XBD=281 XHG=804 XBD=345 XBD=468 XBD=555 XBD=645 XBD=783 XBD=870 XBD=1108 XBD=1293 XHG=112 XHG=301 XHG=360 XHG=489 XHG=575 XHG=664 XHG=890YBD=2343 XHG=1129 YBD=2351 YBD=2350 YBD=2351 YBD=2351 YHG=2314>majority YHG=2314>of YHG=2313>these YHG=2313>did YHG=2314>not YHG=2321>group YHG=2313>the YHG=2314>haemolytic YHG=2314>strepto-: " XBD=1771 XBD=1875 XBD=1982 XHG=1668 XHG=1787 XHG=1890 YBD=2387 YBD=2386 YHG=2359>Pulv. YHG=2358>zinci YHG=2357>oxid. |>" XBD=341 XBD=452 XBD=641 XBD=761 XBD=875 XBD=1056 XBD=1116 XBD=1292 XBD=204 XHG=218 XHG=358 XHG=467 XHG=692 XHG=778 XHG=892 XHG=1074 XHG=1134 XHG=105 YBD=2390 YBD=2383 YBD=2382 YBD=2383 YBD=2383 YBD=2388 YHG=2353>which YHG=2353>they YHG=2352>isolated-. YHG=2352>We YHG=2361>were YHG=2352>inclined YHG=2353>cocci YHG=2353>to YHG=2353>believe, XBD=151 XBD=226 XBD=338 XBD=555 XBD=624 XBD=778 XBD=885 XBD=966 XBD=1055 XBD=1296 XHG=100 XHG=161 XHG=242 XHG=352 XHG=570 XHG=639 XHG=797 XHG=900 XHG=981 XHG=1070 YBD=2429 YBD=2427 YBD=2424 YBD=2422 YBD=2422 YBD=2429 YHG=2390>as YHG=2393>has YHG=2392>been YHG=2391>suggested YHG=2391>by YHG=2391>others, YHG=2391>that YHG=2392>the YHG=2392>low YHG=2392>proportion "|>"XBD=2167 XBD=1771 XBD=1895 XBD=1988 XBD=1953 XHG=1668 XHG=1787 XHG=1969 XHG=2005 XHG=1909 YBD=2433 YBD=2424 YBD=2426 YBD=2425 YHG=2398>Pulv. YHG=2397>amyli YHG=2398>2 YHG=2397>drachms YHG=2392>aa <9.YBD=2469 "|>"XBD=1294 XBD=149 XBD=258 XBD=441 XBD=862 XBD=925 XBD=1142 XBD=1211 XBD=725 XHG=103 XHG=160 XHG=272 XHG=738 XHG=877 XHG=941 XHG=1158 XHG=1227 XHG=544 YBD=2468 YBD=2461 YBD=2467 YBD=2469 YBD=2462 YHG=2427>of YHG=2437>cases YHG=2431>yielding YHG=2431>might YHG=2431>be YHG=2431>explained YHG=2439>pyogenes YHG=2431>by YHG=2432>the XBD=1797 XBD=1893 XBD=1993 XBD=1471 XHG=1667 XHG=1805 XHG=1908 XHG=1466 YBD=2473 YBD=2463 YBD=2472 YBD=2447 YHG=2436>Adipis YHG=2437>laned YHG=2436>hyd. YHG=2443>’ |>" " XBD=1961 XBD=2020 XBD=2055 XBD=2234 XBD=1832 XHG=1846 XHG=1976 XHG=2036 XHG=2071 XHG=1667 YBD=2502 YBD=2503 YBD=2503 YHG=2475>mollis YHG=2476>aa. YHG=2476>2 YHG=2476>drachms YHG=2474>Paraffini XBD=191 XBD=333 XBD=472 XBD=565 XBD=731 XBD=898 XBD=1086 XBD=1167 XBD=1294 XHG=99 XHG=204 XHG=347 XHG=487 XHG=580 XHG=746 XHG=914 XHG=1100 XHG=1184 YBD=2508 YBD=2500 YBD=2499 YBD=2507 YBD=2508 YBD=2500 YBD=2501 YBD=2500 YHG=2470>long YHG=2470>period YHG=2470>which YHG=2469>had YHG=2470>usually YHG=2470>elapsed YHG=2470>between YHG=2470>the YHG=2471>onset " XBD=1292 XBD=150 XHG=626 XBD=232 XBD=401 XBD=505 XBD=601 XBD=897 XBD=1003 XBD=1109 XBD=1210 XHG=112 XHG=169 XHG=258 XHG=428 XHG=532 XHG=949YBD=2539 XHG=1030 XHG=1133 XHG=1236 YBD=2538 YBD=2538 YBD=2539 YHG=2508>of YHG=2509>the YHG=2508>disease YHG=2508>and YHG=2515>our YHG=2509>examination. YHG=2509>To YHG=2509>test YHG=2510>this YHG=2519>we

" XBD=1476 XBD=1687 XBD=1968 XBD=2087 XBD=2249 XBD=2349 XBD=2425 XBD=2556 XHG=1402 XHG=1492 XHG=1759 XHG=1991 XHG=2111 XHG=2301 XHG=2374 XHG=2450 YBD=2564 YBD=2562 YBD=2558 YBD=2559 YBD=2560 YHG=2528>Six YHG=2529>methods YHG=2529>treatment YHG=2538>were YHG=2529>tested. YHG=2529>In YHG=2530>all YHG=2539>cases " |>" XBD=302 XBD=396 XBD=651 XBD=722 XBD=916 XBD=1104 XBD=1190 XBD=1291 XHG=103 XHG=328 XHG=424 XHG=677 XHG=746 XHG=938 XHG=1130 XHG=1217 YBD=2584 YBD=2577 YBD=2585 YBD=2578 YBD=2578 YHG=2547>compared YHG=2548>the YHG=2548>percentage YHG=2548>of YHG=2547>cultures YHG=2547>positive YHG=2548>for YHG=2548>Str. " XBD=1483 XBD=1593 XBD=1792 XBD=2085 XBD=2214 XBD=2256 XBD=2364 XBD=2465 XBD=2556 XHG=1353 XHG=1495 XHG=1610 XHG=1808 XHG=2103 XHG=2232 XHG=2275 XHG=2416 XHG=2483 YBD=2600 YBD=2603 YBD=2604 YBD=2605 YBD=2598 YBD=2599 YHG=2568>crusts YHG=2577>were YHG=2567>removed YHG=2568>mechanically YHG=2567>twice YHG=2577>a YHG=2568>day. YHG=2569>In YHG=2579>one " XBD=276 XBD=395 XBD=485 XBD=691 XBD=760 XBD=846 XBD=1028 XBD=1202 XHG=99 XHG=300 XHG=419 XHG=512 XHG=711 XHG=873 XHG=1078 XHG=1226 YBD=2623 YBD=2616 YBD=2617 YBD=2617 YBD=2616 YHG=2594>,pyogenes YHG=2586>with YHG=2586>the YHG=2586>duration YHG=2587>of YHG=2587>the YHG=2587>disease. YHG=2587>When YHG=2587>the " XBD=1293 XBD=1473XHG=780 XBD=1823 XBD=1943 XBD=2172 XBD=2260 XBD=2337 XBD=2441 XBD=2556 XHG=1353 XHG=1510 XHG=1857 XHG=1971 XHG=2209 XHG=2295 XHG=2373 XHG=2477 YBD=2644 YBD=2643 YBD=2637 YBD=2638 YHG=2614>group YHG=2602>sulphapyridine YHG=2616>was YHG=2606>powdered YHG=2616>on YHG=2608>to YHG=2607>the YHG=2617>raw

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of

XBD=1293 XBD=191 XBD=347 XBD=452 XBD=733 XBD=799 XBD=916 XBD=980 XBD=1062 XBD=1204 XHG=99 XHG=202 XHG=367 XHG=464 XHG=755 XHG=821 XHG=937 XHG=995 XHG=1083 XHG=1225 YBD=2655 YBD=2654 YBD=2663 YBD=2655 YBD=2655 YBD=2661 YBD=2656 YHG=2623>firstYHG=2625>culture YHG=2626>was YHG=2626>made-within YHG=2625>15 YHG=2625>days YHG=2626>of YHG=2625>the YHG=2626>onset, YHG=2626>the XBD=1490 XBD=1655 XBD=1717 XBD=1795 XBD=1931 XBD=2024 XBD=2118 XBD=2262 XBD=2319 XBD=2444 XBD=2557 XHG=1354 XHG=1505 XHG=1672 XHG=1728 XHG=1810 XHG=1947 XHG=2040 XHG=2134 XHG=2277 XHG=2335 XHG=2460 YBD=2682 YBD=2674 YBD=2677 YBD=2675 YBD=2683 YBD=2676 YHG=2645>oozing YHG=2646>surface YHG=2645>of YHG=2646>the YHG=2645>lesion YHG=2646>and YHG=2654>was YHG=2645>sealed YHG=2645>in YHG=2646>place YHG=2647>with XBD=323 XBD=453 XBD=560 XBD=774 XBD=885 XBD=1017 XBD=1191 XBD=1292 XHG=105 XHG=357 XHG=487 XHG=594 XHG=808 XHG=920 XHG=1067 XHG=1225 YBD=2701 YBD=2694 YBD=2693 YBD=2694 YHG=2662>percentage YHG=2664>with YHG=2664>Str. YHG=2673>pyogenes YHG=2673>was YHG=2663>21-5. YHG=2665>When YHG=2665>the XBD=1420 XBD=1560 XBD=1784 XBD=1920 XBD=2016 XBD=2184 XBD=2243 XBD=2327 XBD=2451 XBD=2556 XHG=1353 XHG=1438 XHG=1611 XHG=1801 XHG=1939 XHG=2034 XHG=2201 XHG=2259 XHG=2344 XHG=2468 YBD=2721 YBD=2720 YBD=2713 YBD=2714 YBD=2715 YBD=2722 YHG=2683>the YHG=2685>paste. YHG=2684>Another YHG=2692>group YHG=2692>was YHG=2684>treated YHG=2685>in YHG=2685>the YHG=2694>same YHG=2694>way XBD=263 XBD=449 XBD=573 XBD=664 XBD=942 XBD=1033 XBD=1166 XBD=1291 XHG=102 XHG=277 XHG=463 XHG=587 XHG=679 XHG=955 XHG=1050 XHG=1184 YBD=2732 YBD=2734 YBD=2732 YBD=2734 YBD=2740 YHG=2702>interval YHG=2703>between YHG=2703>onset YHG=2703>and YHG=2703>examination YHG=2712>was YHG=2704>16-30 YHG=2703>days, XBD=1491 XBD=1599 XBD=1938 XBD=2035 XBD=2148 XBD=2319 XBD=2385 XBD=2554 XHG=1353 XHG=1510 XHG=1619 XHG=1957 XHG=2054 XHG=2168 XHG=2339 XHG=2400 YBD=2760 YBD=2752 YBD=2755 YBD=2753 YBD=2754 YBD=2761 YHG=2723>except YHG=2722>that YHG=2722>sulphanilamide YHG=2731>was YHG=2723>used YHG=2723>instead YHG=2724>of YHG=2724>sulphaXBD=168 XBD=412 XBD=600 XBD=699 XBD=820 XBD=919 XBD=1046 XBD=1193 XBD=1292 XHG=111 XHG=189 XHG=435 XHG=622 XHG=724 XHG=872 XHG=923 XHG=1067 XHG=1214 YBD=2770 YBD=2779 YBD=2772 YBD=2771 YBD=2779 YBD=2772 YHG=2740>the YHG=2742>percentage YHG=2742>positive YHG=2751>was YHG=2741>50-0. YHG=2742>In YHG=2751>cases YHG=2742>which YHG=2742>had XBD=1540 XBD=1712 XBD=1881 XBD=2007 XBD=2188 XBD=2315 XBD=2554 XHG=1352 XHG=1592 XHG=1743 XHG=1910 XHG=2038 XHG=2218 XHG=2344 YBD=2791 YBD=2792 YBD=2793 YBD=2799 YHG=2762>pyridine. YHG=2761>Three YHG=2769>groups YHG=2770>were YHG=2762>treated YHG=2762>with YHG=2762>sulphanilXBD=246 XBD=325 XBD=437 XBD=504 XBD=636 XBD=782 XBD=848 XBD=933 XBD=1120 XBD=1292 XHG=112 XHG=265 XHG=346 XHG=459 XHG=529 XHG=659 XHG=806 XHG=866 XHG=955 XHG=1140 YBD=2810 YBD=2819 YBD=2811 YBD=2811 YBD=2818 YHG=2780>existed YHG=2781>for YHG=2790>over YHG=2782>30 YHG=2782>days, YHG=2781>85-7% YHG=2781>of YHG=2775>the YHG=2781>cultures YHG=2781>yielded XBD=1478 XBD=1776 XBD=1844 XBD=1939 XBD=2077 XBD=2147 XBD=2486 XBD=2560 XHG=1342 XHG=1506 XHG=1803 XHG=1872 XHG=1967 XHG=2106 XHG=2176 XHG=2515 YBD=2834 YBD=2837 YBD=2831 YBD=2830 YHG=2800>amide YHG=2800>incorporated YHG=2801>in YHG=2800>the YHG=2802>paste YHG=2802>in YHG=2802>concentrations YHG=2801>of XBD=175 XBD=379 XHG=112 YBD=2848 YBD=2857 YHG=2818>Str. YHG=2829>pyogenes. XBD=1452XHG=192 XBD=1562 XBD=1660 XBD=1756 XBD=1980 XBD=2042 XBD=2127 XBD=2254 XBD=2406 XBD=2555 XHG=1353 XHG=1477 XHG=1583 XHG=1682 XHG=1806 XHG=2000 XHG=2060 XHG=2146 XHG=2272 XHG=2427 YBD=2868 YBD=2875 YBD=2870 YBD=2872 YBD=2876 YBD=2869 YHG=2838>20%, YHG=2839>10% YHG=2839>and YHG=2839>5%. YHG=2839>Patients YHG=2839>in YHG=2840>the YHG=2840>sixth YHG=2848>group, YHG=2839>which

" XBD=2555 XBD=1465 XBD=1521 XBD=1559 XBD=1733 XBD=1843 XBD=2007 XBD=2115 XBD=2193 XBD=2317 XHG=1351 XHG=1478 XHG=1535 XHG=1573 XHG=1747 XHG=1856 XHG=2019 XHG=2128 XHG=2206 XHG=2331 XHG=2508 YBD=2906 YBD=2911 YBD=2908 YBD=2914 YBD=2907 YBD=2905 YHG=2878>acted YHG=2887>as YHG=2887>a YHG=2877>control, YHG=2886>were YHG=2878>treated YHG=2879>with YHG=2879>the YHG=2879>paste YHG=2878>alone. YHG=2877>In " XBD=2454 XBD=232 XHG=673 XBD=555 XBD=637 XBD=968 XBD=1272 XHG=97 XHG=264 XHG=593 XHG=1000 YBD=2916 YBD=2917 YBD=2918 YBD=2919 YHG=2895>TABLE YHG=2897>III-INCIDENCE YHG=2898>OF YHG=2897>STREPTOCOCCUS YHG=2896>PYOGENES IN " XBD=2555 XBD=1405 XBD=1534 XBD=1625 XBD=1760 XBD=1861 XBD=2039 XBD=2105 XBD=2197 XBD=2360 XBD=2463 XHG=2488 XHG=1351 XHG=1428 XHG=1558 XHG=1650 XHG=1784 XHG=1885 XHG=2063 XHG=2130 XHG=2220 XHG=2384 YBD=2952 YBD=2953 YBD=2945 YBD=2947 YBD=2946 YBD=2944 YHG=2916>all YHG=2925>cases YHG=2916>the YHG=2915>paste YHG=2924>was YHG=2916>applied YHG=2918>to YHG=2917>the YHG=2916>lesions YHG=2915>and YHG=2915>the " XBD=535 XHG=821 XBD=597 XBD=804 XBD=865 XBD=1033 XHG=350 XHG=553 XHG=614 XHG=880 YBD=2957 YBD=2956 YBD=2957 YHG=2936>RELATION YHG=2936>TO YHG=2936>DURATION YHG=2936>OF YHG=2934>DISEASE " XBD=2553 XBD=1571 XHG=2476 XBD=1688 XBD=1794 XBD=1915 XBD=2022 XBD=2150 XBD=2222 XBD=2446 XHG=1351 YBD=2989 XHG=1599 XHG=1715 XHG=1820 XHG=1944 XHG=2049 XHG=2179 XHG=2274 YBD=2983 YHG=2962>was YBD=2991 YBD=2984 YHG=2954>unaffected YHG=2954>skin YHG=2963>was YHG=2954>kept YHG=2955>free YHG=2955>from YHG=2954>it. YHG=2953>Shaving " XBD=1568 XHG=1351 YBD=3027 YHG=2992>forbidden.

" XBD=2555 XBD=1520 XHG=2439 XBD=1575 XBD=1719 XBD=1839 XBD=1923 XBD=2090 XBD=2232 XBD=2338 XBD=2422 XHG=1401 YBD=3059 XHG=1536 XHG=1593 XHG=1736 XHG=1857 XHG=1940 XHG=2108 XHG=2249 XHG=2355 YBD=3063 YHG=3038>mean YBD=3067 YBD=3062 YBD=3066 YBD=3061 YBD=3060 YHG=3031>Table YHG=3038>v, YHG=3031>which YHG=3031>gives YHG=3032>the YHG=3031>results, YHG=3031>shows YHG=3030>that YHG=3030>the " XBD=2554 XBD=1534 XHG=2437 XBD=1597 XBD=1822 XBD=1882 XBD=1967 XBD=2033 XBD=2158 XBD=2301 XBD=2418 XHG=1352 YBD=3097 XHG=1553 XHG=1612 XHG=1840 XHG=1900 XHG=1987 XHG=2053 XHG=2176 XHG=2319 YBD=3101 YHG=3068>cured YBD=3100 YBD=3099 YHG=3070>duration YHG=3070>of YHG=3070>treatment YHG=3070>in YHG=3071>the YHG=3070>89 YHG=3078>cases YHG=3068>which YHG=3076>were

" " " "

XBD=2553 XBD=1428 XBD=1507 XBD=1634 XBD=1766 XBD=1896 XBD=2094 XBD=2151 XBD=2264 XBD=2401 XBD=1451 XBD=1571 XBD=1668 XBD=1775 XBD=1919 XBD=1977 XBD=2062 XBD=2191 XBD=2372 XBD=2434 XBD=2554 XBD=1392 XBD=1470 XBD=1622 XBD=1702 XBD=1934 XBD=2010 XBD=2210 XBD=2292 XBD=2553 XBD=1580 XBD=1693 XBD=1868 XBD=2030 XBD=2120 XBD=2206 XBD=2554

XHG=2420 XHG=1350 XHG=1446 XHG=1527 XHG=1687 XHG=1782 XHG=1912 XHG=2110 XHG=2168 XHG=2280 XHG=1349 XHG=1468 XHG=1588 XHG=1685 XHG=1795 XHG=1935 XHG=1996 XHG=2081 XHG=2209 XHG=2389 XHG=2449 XHG=1350 XHG=1403 XHG=1483 XHG=1635 XHG=1714 XHG=1946 XHG=2021 XHG=2221 XHG=2303 XHG=1351 XHG=1630 XHG=1717 XHG=1893 XHG=2053 XHG=2145 XHG=2232

YBD=3135 YBD=3145 YBD=3138 YBD=3136 YBD=3137 YBD=3142 YBD=3175 YBD=3181 YBD=3183 YBD=3176 YBD=3173 YBD=3174 YBD=3214 YBD=3222 YBD=3216 YBD=3215 YBD=3221 YBD=3213 YBD=3220 YBD=3257 YBD=3261 YBD=3252 YBD=3259 YBD=3258

YHG=3106>varied YHG=3117>was YHG=3108>8-3 YHG=3108>days. YHG=3108>The YHG=3117>mean YHG=3108>duration YHG=3108>in YHG=3103>each YHG=3115>group YHG=3146>little YHG=3146>from YHG=3146>this YHG=3147>and, YHG=3147>owing YHG=3147>to YHG=3147>the YHG=3145>small YHG=3144>number YHG=3144>of YHG=3153>cases YHG=3185>in YHG=3193>groups YHG=3185>the YHG=3185>differences YHG=3194>are YHG=3183>probably YHG=3183>not YHG=3182>statistically YHG=3223>significant. YHG=3224>All YHG=3232>groups, YHG=3223>except YHG=3223>the YHG=3221>5% YHG=3221>sulphanilamide

" XBD=2553 XBD=1474 XHG=2486 XBD=1704 XBD=1832 XBD=1979 XBD=2097 XBD=2385 XBD=2463 XHG=1351 YBD=3290 XHG=1498 XHG=1728 XHG=1855 XHG=2001 XHG=2120 XHG=2408 YBD=3298 YHG=3261>the YBD=3292 YBD=3291 YBD=3297 YHG=3262>paste, YHG=3262>contained YHG=3271>cases YHG=3262>which YHG=3269>were YHG=3260>uncontrolled YHG=3260>by " XBD=2553 XBD=1563 XHG=2486 XBD=1693 XBD=1824 XBD=1943 XBD=2194 XBD=2264 XBD=2391 XBD=2459 XHG=1351 YBD=3329 XHG=1588 XHG=1746 XHG=1851 XHG=1968 XHG=2220 XHG=2287 XHG=2418 YBD=3330 YHG=3299>the YBD=3336 YBD=3328 YHG=3300>treatment YHG=3302>used. YHG=3301>The YHG=3301>high YHG=3299>proportion YHG=3299>of YHG=3307>cases YHG=3299>in " XBD=2553 XBD=1374 XHG=2520 XBD=1503 XBD=1671 XBD=1812 XBD=2062 XBD=2124 XBD=2253 XBD=2502 XHG=1353 YBD=3369 XHG=1392 XHG=1522 XHG=1692 XHG=1832 XHG=2080 XHG=2143 XHG=2271 YBD=3351 YHG=3339>is YBD=3374 YBD=3376 YBD=3367 YBD=3366 YBD=3368 YHG=3338>&dquo;&dquo; YHG=3339>paste YHG=3338>alone YHG=3347>group YHG=3338>transferred YHG=3338>to YHG=3337>other YHG=3338>treatments XBD=261 XBD=337 XBD=489 XBD=584 XBD=749 XBD=871 XBD=950 XBD=1143 XBD=1288 XHG=151 XHG=289 XHG=365 XHG=517 XHG=611 XHG=775 XHG=898 XHG=978 XHG=1176 YBD=3403 YBD=3404 YBD=3405 YBD=3406 YBD=3411 YHG=3374>Table YHG=3383>ill YHG=3377>shows YHG=3376>the YHG=3376>results YHG=3375>with YHG=3376>all YHG=3376>cultures YHG=3376>(230), |>" " XBD=1556 XBD=1625 XBD=1708 XBD=1805 XBD=1922 XBD=2049 XBD=2143 XBD=2371 XBD=2553 XBD=2465 XHG=1351 XHG=1572 XHG=1641 XHG=1724 XHG=1821 XHG=1939 XHG=2065 XHG=2160 XHG=2482 XHG=2386 YBD=3412 YBD=3413 YBD=3410 YBD=3405 YBD=3406 YBD=3407 YBD=3413 YHG=3376>explained YHG=3377>by YHG=3378>the YHG=3378>fact YHG=3377>that, YHG=3376>when YHG=3375>this YHG=3376>treatment YHG=3378>not YHG=3385>was " XBD=1289 XBD=288 XBD=406 XBD=527 XBD=674 XBD=902 XHG=107 XHG=297 XHG=413 XHG=538 XHG=949 YBD=3448 YBD=3443 YBD=3449 YBD=3442 YBD=3451 YHG=3410>including YHG=3414>those YHG=3414>made YHG=3413>during YHG=3413>treatment. YHG=3414>The figure shows XBD=1558XHG=681 XBD=1714 XBD=1800 XBD=1928 XBD=2001 XBD=2250 XBD=2349 XBD=2552 XHG=1351 XHG=1577 XHG=1733 XHG=1820 XHG=1950 XHG=2021 XHG=2270 XHG=2369 YBD=3450 YBD=3443 YBD=3444 YBD=3445 YBD=3453 YHG=3415>successful YHG=3415>within YHG=3416>ten YHG=3414>days, YHG=3423>an YHG=3414>alternative YHG=3424>was YHG=3415>adopted. XBD=328 XHG=795 XBD=436 XBD=525 XBD=771 XBD=838 XBD=1022 XBD=1208 XBD=1290 XHG=99 XHG=349 XHG=457 XHG=547 XHG=848 XHG=1044 XHG=1228 YBD=3486 YBD=3488 YBD=3480 YBD=3482 YBD=3489 YHG=3450>graphically YHG=3452>how YHG=3451>the YHG=3452>percentage YHG=3452>of YHG=3452>cultures YHG=3453>positive YHG=3452>for " XBD=2552 XBD=1471 XBD=1524 XBD=1644 XBD=1788 XBD=1906 XBD=1962 XBD=2043 XBD=2223 XBD=2455 XHG=1351 XHG=1491 XHG=1543 XHG=1664 XHG=1806 XHG=1927 XHG=1977 XHG=2063 XHG=2243 XHG=2474 YBD=3483 YBD=3487 YBD=3481 YBD=3482 YBD=3490 YBD=3484 YBD=3485 YHG=3451>There YHG=3453>is YHG=3453>little YHG=3454>doubt YHG=3453>that, YHG=3452>if YHG=3452>the YHG=3452>original YHG=3454>treatment YHG=3454>had

,

546

" XBD=2502 XBD=1434 XBD=1598 XBD=1722 XBD=1849 XBD=2011 XBD=2188 XBD=2308 XBD=2423 XHG=1337 XHG=1463 XHG=1627 XHG=1748 XHG=1876 XHG=2038 XHG=2216 XHG=2333 XHG=2445 YBD=241 YBD=236 YBD=242 YBD=240 YBD=234 YBD=235 YHG=215>were YHG=206>crusts, YHG=206>fluid YHG=206>from YHG=206>oozing YHG=206>lesions, YHG=205>fluid YHG=205>from YHG=214>unXBD=169 XHG=801 XBD=410 XBD=466 XBD=540 XBD=580 XBD=666 XBD=784 XBD=908 XBD=1065 XBD=1131 XBD=1273 XHG=73 XHG=183 XHG=424 XHG=479 XHG=554 XHG=593 XHG=680 XHG=924 XHG=1080 XHG=1145 YBD=236 YBD=236 YBD=237 YBD=244 YBD=237 YBD=237 YHG=206>been YHG=206>persevered YHG=207>in YHG=207>for YHG=217>a YHG=207>few YHG=217>more YHG=207>days, YHG=207>almost YHG=207>all YHG=206>would

" " " " "

XBD=2505 XBD=1486 XBD=1684 XBD=1814 XBD=2072 XBD=2151 XBD=2313 XHG=1338 XHG=1527 XHG=1719 XHG=1830 XHG=2107 XHG=2188 XHG=2352 YBD=282 YBD=275 YBD=276 YBD=274 YBD=280 YBD=281 YHG=244>opened YHG=244>vesicles YHG=245>and, YHG=245>suspensions YHG=244>of YHG=243>Staph. YHG=251>pyogenes XBD=173 XHG=508 XBD=289 XBD=421 XBD=492 XBD=552 XHG=74 XHG=191 XHG=305 XHG=438 YBD=276 YBD=275 YBD=284 YBD=276 YHG=245>have YHG=246>been YHG=246>cured YHG=246>by YHG=247>it. XBD=1503 XHG=2425 XBD=1619 XBD=1739 XBD=1800 XBD=2007 XBD=2138 XBD=2244 XBD=2413 XBD=2505 XHG=1340 YBD=311 XHG=1518 XHG=1636 XHG=1755 XHG=1811 XHG=2059 XHG=2154 XHG=2260 YBD=313 YHG=290>were YBD=320 YBD=312 YHG=282>isolated YHG=284>from YHG=292>cases YHG=283>of YHG=283>impetigo. YHG=283>The YHG=282>sites YHG=282>selected XBD=336 XBD=583 XBD=644 XBD=879 XBD=936 XBD=1016 XBD=1141 XHG=217 XHG=353 XHG=600 XHG=660 XHG=956 XHG=1034 YBD=345 YBD=343 YBD=341 YBD=342 YBD=342 YHG=322>TABLE YHG=323>V-RESULTS YHG=323>OF YHG=321>TREATMENT YHG=321>IN YHG=314>100 YHG=321>CASES XBD=1410XHG=895 XBD=1538 XBD=1643 XBD=1747 XBD=1820 XBD=2060 XBD=2242 XBD=2342 XBD=2426 XBD=2505 XHG=1342 XHG=1437 XHG=1566 XHG=1670 XHG=1776 XHG=1842 XHG=2088 XHG=2269 XHG=2367 XHG=2449 YBD=353 YBD=352 YBD=358 YBD=351 YBD=359 YBD=350 YHG=322>the YHG=331>arms YHG=322>and YHG=322>legs YHG=322>of YHG=322>unaffected YHG=329>persons YHG=320>and YHG=320>the YHG=329>unXBD=1508 XHG=2351 XBD=1614 XBD=1676 XBD=1757 XBD=1877 XBD=1973 XBD=2108 XBD=2171 XBD=2336 XBD=2507 XHG=1344 YBD=396 XHG=1527 XHG=1632 XHG=1691 XHG=1775 XHG=1896 XHG=1992 XHG=2127 XHG=2184 YBD=392 YHG=359>suffering YBD=391 YBD=390 YBD=397 YHG=361>affected YHG=361>skin YHG=361>of YHG=361>the YHG=361>faces YHG=360>and YHG=361>necks YHG=360>of YHG=368>persons

" XBD=1703 XBD=1446 XHG=1547 XBD=1529 XHG=1346 YBD=431 XHG=1463 YBD=430 YHG=401>disease. YHG=401>from YHG=400>the

" XBD=2512 XBD=1475 XHG=2477 XBD=1691 XBD=1968 XBD=2089 XBD=2457 XHG=1396 YBD=467 XHG=1498 XHG=1714 XHG=1992 XHG=2112 YBD=469 YHG=438>of YBD=468 YBD=476 YHG=440>The YHG=438>following YHG=438>experiments YHG=448>were YHG=437>performed-most " XBD=1813 XBD=1455 XHG=1634 XBD=1618 XHG=1348 YBD=508 YHG=478>times. XHG=1472 YHG=479>them YHG=478>several

" XBD=2511 XBD=1427 XHG=2440 XBD=1573 XBD=1675 XBD=1829 XBD=1880 XBD=1958 XBD=2051 XBD=2136 XBD=2235 XBD=2285 XBD=2428 XHG=1399 YBD=558 XHG=1452 XHG=1587 XHG=1690 XHG=1842 XHG=1895 XHG=1973 XHG=2065 XHG=2149 XHG=2248 XHG=2299 YBD=561 YHG=530>with YBD=560 YBD=569 YBD=559 YBD=567 YHG=533>1. YHG=532>Crusts YHG=541>were YHG=531>applied YHG=534>to YHG=531>the YHG=531>skin YHG=531>and YHG=531>kept YHG=530>in YHG=532>contact " XBD=2050 XBD=1381 XHG=1788 XBD=1450 XBD=1564 XBD=1666 XHG=1350 YBD=607 XHG=1396 XHG=1464 XHG=1580 YBD=599 YHG=570>Elastoplast.’ YHG=571>it YHG=571>for YHG=571>three YHG=570>days

with

" XBD=2511 XBD=1429 XHG=2447 XBD=1557 XBD=1661 XBD=1797 XBD=1936 XBD=2020 XBD=2182 XBD=2233 XBD=2312 XBD=2368 XBD=2435 XHG=1399 YBD=637 XHG=1453 XHG=1571 XHG=1675 XHG=1810 XHG=1950 XHG=2035 XHG=2196 XHG=2248 XHG=2325 XHG=2380 YBD=639 YHG=607>skin YBD=646 YBD=638 YBD=644 YBD=636 YHG=611>2. YHG=610>Fluid YHG=610>from YHG=610>oozing YHG=609>lesions YHG=618>was YHG=609>allowed YHG=610>to YHG=608>dry YHG=617>on YHG=608>the " XBD=1853 XBD=1467 XHG=1646 XBD=1551 XBD=1631 XHG=1353 YBD=677 XHG=1480 XHG=1566 YBD=678 YHG=649>uncovered. YHG=649>which YHG=658>was YHG=648>left

" XBD=2406 XBD=2511 XHG=2423 XBD=1431 XBD=1528 XBD=1623 XBD=1710 XBD=1865 XBD=2070 XBD=2176 XBD=2276 XHG=1401 YBD=722 XHG=1455 XHG=1546 XHG=1639 XHG=1726 XHG=1887 XHG=2090 XHG=2194 XHG=2290 YBD=717 YHG=695>gauze YBD=725 YBD=716 YBD=724 YBD=720 YHG=689>3. ; YHG=688>The YHG=688>skin YHG=697>was YHG=688>treated YHG=688>overnight YHG=688>with YHG=686>10% YHG=686>KOH " XBD=2512 XBD=1550 XHG=2343 XBD=1657 XBD=1761 XBD=1869 XBD=1944 XBD=2094 XBD=2228 XBD=2320 XBD=2468 XHG=2482 YBD=754 XHG=1355 XHG=1570 XHG=1674 XHG=1779 XHG=1896 XHG=1972 XHG=2121 XHG=2251 YBD=763 YHG=728>to YBD=755 YBD=753 YBD=762 YHG=727>moistened YHG=727>with YHG=726>fluid YHG=728>from YHG=735>an YHG=727>oozing YHG=727>lesion YHG=734>was YHG=725>applied " XBD=2515 XBD=1418 XHG=2444 XBD=1569 XBD=1657 XBD=1738 XBD=1835 XBD=1883 XBD=2036 XBD=2135 XBD=2175 XBD=2239 XBD=2345 XBD=2434 XHG=1355 YBD=801 XHG=1429 XHG=1579 XHG=1668 XHG=1749 XHG=1847 XHG=1895 XHG=2047 XHG=2145 XHG=2187 XHG=2248 XHG=2356 YBD=803 YHG=765>with YBD=794 YBD=793 YHG=765>the YHG=765>treated YHG=765>skin YHG=765>and YHG=765>kept YHG=766>in YHG=768>contact YHG=766>it YHG=765>for YHG=764>three YHG=765>days " XBD=1573 XHG=1356 YBD=842 YHG=805>elastoplast. " XBD=2514 XBD=1435 XHG=2359 XBD=1532 XBD=1628 XBD=1715 XBD=1905 XBD=2009 XBD=2133 XBD=2344 XBD=2440 XHG=2454 YBD=873 XHG=1404 XHG=1459 XHG=1550 XHG=1645 XHG=1733 XHG=1921 XHG=2025 XHG=2153 YBD=880 YHG=843>with YBD=872 YBD=871 YHG=852>ace. YHG=845>4. YHG=844>The YHG=843>skin YHG=853>was YHG=844>scrubbed YHG=844>with YHG=853>gauze YHG=843>moistened

" XBD=2515 XBD=1452 XHG=2466 XBD=1631 XBD=1750 XBD=1853 XBD=1973 XBD=2206 XBD=2368 XBD=2439 XHG=1357 YBD=913 XHG=1498 XHG=1663 XHG=1782 XHG=1885 XHG=2006 XHG=2238 XHG=2399 YBD=912 YHG=883>the YBD=921 YBD=911 YHG=886>tone. YHG=883>Vesicle YHG=883>fluid YHG=892>was YHG=883>then YHG=883>vigorously YHG=882>rubbed YHG=891>on " XBD=2516 XBD=1497 XHG=2395 XBD=1595 XBD=1726 XBD=1813 XBD=1944 XBD=2026 XBD=2239 XBD=2295 XBD=2378 XHG=1357 YBD=953 XHG=1515 XHG=1612 XHG=1742 XHG=1831 XHG=1960 XHG=2043 XHG=2257 XHG=2310 YBD=952 YHG=925>covered YBD=951 YBD=950 YHG=922>treated YHG=931>area YHG=922>which YHG=932>was YHG=922>either YHG=922>left YHG=923>uncovered YHG=932>or YHG=931>was

" XBD=2159 XBD=1446 XHG=1942 XBD=1566 XBD=1664 XBD=1715 XBD=1826 XBD=1929 XHG=1357 YBD=1000 XHG=1459 XHG=1580 XHG=1678 XHG=1728 XHG=1841 YBD=998 YHG=961>with YBD=999 YBD=990 YHG=962>with YHG=971>gauze YHG=962>held YHG=962>in YHG=962>place YHG=962>elastoplast. " XBD=2517 XBD=1435 XHG=2488 XBD=1597 XBD=1649 XBD=1688 XBD=1767 XBD=1883 XBD=1919 XBD=2137 XBD=2191 XBD=2318 XBD=2477 XHG=1405 YBD=1032 XHG=1461 XHG=1611 XHG=1667 XHG=1702 XHG=1782 XHG=1897 XHG=1934 XHG=2151 XHG=2201 XHG=2331 YBD=1029 YHG=1003>in YBD=1039 YBD=1030 YBD=1038 YHG=1002>5. YHG=1001>Similar YHG=1004>to YHG=1003>4 YHG=1001>but YHG=1001>using YHG=1009>a YHG=1002>suspension YHG=1002>of YHG=1000>Staph. YHG=1010>pyogenes " XBD=1476 XHG=1357 YBD=1069 YHG=1040>broth. " XBD=1296 XBD=201 XHG=791 XBD=287 XBD=355 XBD=485 XBD=632 XBD=770 XBD=834 XBD=1013 XBD=1069 XHG=148 XHG=219 XHG=312 XHG=381 XHG=507 XHG=653 XHG=849YBD=1087 XHG=1026 XHG=1084 YBD=1088 YBD=1095 YBD=1088 YHG=1058>Of YHG=1057>the YHG=1058>11 YHG=1066>cases YHG=1057>which YHG=1056>failed YHG=1057>to YHG=1057>respond YHG=1057>to YHG=1057>treatment XBD=1516 XBD=1584 XBD=1710 XBD=1912 XBD=1980 XBD=2234 XBD=2436 XHG=1407 XHG=1541 XHG=1603 XHG=1734 XHG=1936 XHG=1999 XHG=2256 XHG=2457 YBD=1124 YBD=1125 YBD=1132 YBD=1134 YHG=1094>None YHG=1094>these YHG=1093>methods YHG=1094>of YHG=1094>inoculation YHG=1094>produced YHG=1104>any " XBD=2518 XBD=120 XHG=753 XBD=263 XBD=437 XBD=531 XBD=733 XBD=796 XBD=1020 XBD=1137 XBD=1205 XBD=1296 XHG=99 XHG=147 XHG=284 XHG=458 XHG=552 XHG=817 XHG=1041 XHG=1158 XHG=1228 YBD=1126 YBD=1133 YBD=1126 YBD=1134 YBD=1127 YBD=1135 YBD=1127 YBD=1135 YHG=1096>8 YHG=1097>(73%) YHG=1096>yielded YHG=1096>Str. YHG=1105>pyogenes YHG=1106>as YHG=1097>compared YHG=1096>with YHG=1097>39 YHG=1106>per XBD=1507 XBD=1637 XBD=1854 XBD=2071 XBD=2191 XBD=2310 XHG=1357 XHG=1558 XHG=1660 XHG=1877 XHG=2095 XHG=2216 XHG=2330 YBD=1163 YBD=1170 YBD=1164 YBD=1167 YHG=1134>lesions. YHG=1133>The YHG=1133>following YHG=1133>materials YHG=1143>were YHG=1134>then YHG=1134>inoculated " XBD=2518 XBD=198 XHG=880 XBD=379 XBD=453 XBD=539 XBD=733 XBD=786 XBD=867 XBD=926 XBD=1046 XBD=1185 XBD=1295 XHG=99 XHG=213 XHG=391 XHG=466 XHG=553 XHG=745 XHG=799 XHG=941 XHG=1059 XHG=1197 YBD=1166 YBD=1172 YBD=1167 YBD=1174 YBD=1166 YBD=1167 YHG=1136>cent. YHG=1136>positive YHG=1135>for YHG=1135>Str. YHG=1144>pyogenes YHG=1136>in YHG=1137>the YHG=1137>89 YHG=1145>cases YHG=1136>which YHG=1145>were " XBD=2519 XBD=1412 XBD=1604 XBD=1701 XBD=1964 XBD=2065 XBD=2206 XBD=2351 XBD=2441 XHG=1357 XHG=1440 XHG=1633 XHG=1728 XHG=1991 XHG=2094 XHG=2235 XHG=2377 XHG=2464 YBD=1209 YBD=1210 YBD=1203 YBD=1204 YBD=1206 YHG=1173>by YHG=1173>scratch, YHG=1173>the YHG=1172>inoculation YHG=1173>site YHG=1173>being YHG=1173>either YHG=1174>left YHG=1183>unXBD=214 XHG=570 XBD=287 XBD=373 XBD=552 XBD=791 XHG=99 XHG=233 XHG=305 XHG=392 YBD=1204 YBD=1205 YBD=1212 YBD=1206 YHG=1174>cured YHG=1175>by YHG=1174>the YHG=1175>original YHG=1175>treatment. "" XBD=2520 XBD=1519 XBD=1580 XBD=1714 XBD=1895 XBD=2011 XBD=2051 XBD=2195 XBD=2379 XBD=2475 XHG=1359 XHG=1537 XHG=1599 XHG=1734 XHG=1916 XHG=2027 XHG=2069 XHG=2216 XHG=2393 XHG=2489 YBD=1250 YBD=1242 YBD=1243 YBD=1251 YBD=1246 YHG=1212>covered YHG=1221>or YHG=1212>being YHG=1211>covered YHG=1212>with YHG=1221>a YHG=1213>sterile YHG=1213>dressing YHG=1213>kept YHG=1215>in XBD=217 XBD=285 XBD=369 XBD=563 XBD=686 XBD=865 XBD=979 XBD=1296 XHG=143 XHG=244 XHG=306 XHG=395 XHG=590 XHG=713 XHG=890 XHG=1004 YBD=1258 YBD=1259 YBD=1266 YBD=1260 YBD=1268 YHG=1230>One YHG=1230>of YHG=1230>the YHG=1230>resistant YHG=1239>cases YHG=1230>(treated YHG=1231>with YHG=1231>sulphanilamide " |>" XBD=1466 XBD=1579 XBD=2223 XHG=1359 XHG=1483 XHG=1594 XHG=2218 YBD=1282 YBD=1290 YBD=1292 YHG=1252>place YHG=1252>with YHG=1252>elastoplast YHG=1287>, : " XBD=1843 XBD=252 XBD=353 XBD=539 XBD=728 XBD=850 XBD=973 XBD=1296 XHG=99 XHG=282 XHG=390 XHG=576 XHG=763 XHG=887 XHG=1007 YBD=1306 YBD=1298 YBD=1306 YBD=1299 YBD=1308 YBD=1308 YHG=1269>powder) YHG=1270>and YHG=1270>another YHG=1271>(treated YHG=1270>with YHG=1271>20% YHG=1270>sulphanilamide " XBD=1945 XBD=1437 XBD=1566 XBD=1672 XBD=1810 XHG=1408 XHG=1461 XHG=1581 XHG=1687 XHG=1824 YBD=1337 YBD=1335 YBD=1345 YBD=1336 YHG=1309>6. YHG=1307>Fluid YHG=1309>from YHG=1307>oozing YHG=1307>lesion. XBD=213 XHG=922 XBD=317 XBD=438 XBD=538 XBD=707 XBD=824 XBD=874 XBD=908 XBD=993 XBD=1049 XBD=1151 XBD=1297 XHG=98 XHG=227 XHG=331 XHG=450 XHG=550 XHG=721 XHG=837 XHG=889 XHG=1010 XHG=1063 XHG=1163 YBD=1346 YBD=1338 YBD=1347 YBD=1339 YBD=1339 YBD=1347 YBD=1348 YHG=1310>paste) YHG=1318>were YHG=1310>cured YHG=1310>with YHG=1309>brilliant YHG=1319>green YHG=1310>in YHG=1311>7 YHG=1310>and YHG=1311>16 YHG=1310>days YHG=1319>respec" XBD=1438 XBD=1596 XHG=1408 XHG=1461 XHG=1611 YBD=1376 YHG=1349>7. YHG=1347>Vesicle YHG=1347>fluid. " XBD=1709 XBD=221 XHG=867 XBD=361 XBD=486 XBD=692 XBD=850 XBD=956 XBD=1075 XBD=1189 XBD=1298 XHG=98 XHG=267 XHG=381 XHG=508 XHG=709 XHG=972 XHG=1094 XHG=1208 YBD=1385 YBD=1377 YBD=1383 YBD=1387 YBD=1378 YBD=1387 YBD=1386 YBD=1378 YHG=1348>tively. YHG=1348>Four YHG=1358>cases, YHG=1349>originally YHG=1349>treated YHG=1350>with YHG=1352>paste YHG=1350>only, YHG=1359>were " XBD=2052 XBD=1439 XBD=1675 XBD=1730 XBD=1861 XHG=1409 XHG=1464 XHG=1691 XHG=1742 XHG=1875 YBD=1424 YBD=1416 YBD=1423 YHG=1388>8. YHG=1387>Suspension YHG=1388>of YHG=1386>Staph. YHG=1395>pyogenes. XBD=208 XHG=771 XBD=264 XBD=374 XBD=414 XBD=472 XBD=534 XBD=643 XBD=749 XBD=855 XBD=1165 XBD=1297 XHG=100 XHG=226 XHG=281 XHG=395 XHG=433 XHG=496 XHG=554 XHG=660 XHG=874YBD=1427 XHG=1183 YBD=1416 YBD=1426 YBD=1417 YBD=1426 YBD=1427 YHG=1388>cured YHG=1388>in YHG=1389>from YHG=1389>6 YHG=1391>to YHG=1390>13 YHG=1389>days YHG=1389>with YHG=1389>10% YHG=1389>sulphanilamide YHG=1392>paste. " XBD=2521 XBD=175 XHG=663 XBD=352 XBD=522 XBD=634 XBD=746 XBD=1063 XBD=1201 XBD=1299 XHG=101 XHG=200 XHG=379 XHG=545 XHG=772YBD=1466 XHG=1088 XHG=1227 YBD=1456 YBD=1464 YBD=1457 YBD=1466 YBD=1466 YBD=1457 YHG=1427>One YHG=1427>patient, YHG=1428>treated YHG=1428>with YHG=1428>10% YHG=1428>sulphanilamide YHG=1431>paste, YHG=1438>was " XBD=1490 XBD=1609 XBD=1732 XBD=1942 XBD=2053 XBD=2286 XBD=2351 XHG=1411 XHG=1506 XHG=1625 XHG=1747 XHG=1957 XHG=2069 XHG=2300 XHG=2365 YBD=1471 YBD=1470 YBD=1472 YBD=1479 YBD=1474 YHG=1440>The YHG=1449>same YHG=1441>three YHG=1439>materials YHG=1449>were YHG=1441>inoculated YHG=1441>bv YHG=1442>scarifica" XBD=169 XBD=291 XBD=366 XBD=457 XBD=562 XBD=745 XBD=852 XBD=1017 XBD=1131 XHG=100 XHG=196 XHG=318 XHG=413 XHG=483 XHG=588 XHG=774 XHG=877 XHG=1043 XHG=1158 YBD=1495 YBD=1496 YBD=1505 YBD=1504 YBD=1496 YBD=1497 YBD=1506 YHG=1467>lost YHG=1467>sight YHG=1468>of. YHG=1468>In YHG=1468>four YHG=1468>patients YHG=1468>(one YHG=1469>treated YHG=1468>with YHG=1468>sulpha"" XBD=1300 XBD=1458 XBD=1552 XBD=1813 XBD=1910 XBD=2049 XBD=2235 XBD=2351 XBD=2397 XBD=2523 XHG=1361 XHG=1486 XHG=1578 XHG=1837 XHG=1936 XHG=2076 XHG=2259 XHG=2375 XHG=2420 YBD=1515 YBD=1509 YBD=1510 YBD=1517 YBD=1511 YBD=1513 YHG=1479>tion, YHG=1481>the YHG=1480>inoculation YHG=1480>site YHG=1480>being YHG=1481>covered YHG=1472>with YHG=1490>a YHG=1482>sterile XBD=261 XBD=438 XBD=535 XBD=649 XBD=760 XBD=1077 XBD=1204 XHG=101 XHG=285 XHG=464 XHG=560 XHG=784 XHG=1101 XHG=1230 YBD=1544 YBD=1536 YBD=1545 YBD=1545 YBD=1536 YHG=1506>pyridine YHG=1507>powder, YHG=1510>two YHG=1507>with YHG=1508>sulphanilamide YHG=1510>paste YHG=1508>and " XBD=1300 XBD=1533XHG=677 XBD=1648 XBD=1711 XBD=1839 XBD=1956 XBD=2201 XBD=2273 XBD=2352 XBD=2443 XBD=2523 XHG=1364YBD=1545 XHG=1555 XHG=1670 XHG=1732 XHG=1861 XHG=1977 XHG=2225 XHG=2299 XHG=2377 XHG=2463 YBD=1549YHG=1506>10% YBD=1559 YBD=1556 YBD=1558 YBD=1553 YHG=1520>dressing YHG=1520>kept YHG=1520>in YHG=1520>place YHG=1519>with YHG=1519>elastoplast YHG=1521>(9, YHG=1521>10, YHG=1521>11), YHG=1523>and " XBD=2524 XBD=168 XHG=728 XBD=269 XBD=384 XBD=495 XBD=572 XBD=716 XBD=798 XBD=1043 XBD=1104 XBD=1302 XHG=103 XHG=179 XHG=280 XHG=397 XHG=508 XHG=585 XHG=812YBD=1575 XHG=1055 XHG=1117 YBD=1574 YBD=1584 YBD=1576 YBD=1585 YBD=1584 YHG=1555>one YHG=1546>with YHG=1549>paste YHG=1547>only) YHG=1546>the YHG=1547>disease YHG=1556>was YHG=1547>complicated YHG=1547>by YHG=1547>spreading " XBD=1418 XBD=1625 XBD=1859 XBD=1960 XBD=2151 XBD=2296 XBD=2465 XHG=1364 XHG=1450 XHG=1658 XHG=1893 XHG=1993 XHG=2183 XHG=2327 XHG=2491 YBD=1597 YBD=1589 YBD=1591 YBD=1598 YBD=1592 YBD=1593 YHG=1559>by YHG=1559>multiple YHG=1559>puncture, YHG=1559>the YHG=1560>wounds YHG=1561>being YHG=1560>dressed YHG=1571>as " XBD=1303 XBD=319 XHG=864 XBD=559 XBD=716 XBD=834 XBD=969 XBD=1034 XBD=1174 XHG=104 XHG=347 XHG=605 XHG=745 XHG=997YBD=1615 XHG=1063 XHG=1202 YBD=1615 YBD=1615 YHG=1586>eczematoid YHG=1586>dermatitis. YHG=1587>These YHG=1595>were YHG=1588>cured YHG=1587>in YHG=1587>about YHG=1587>three "" XBD=2525 XBD=1493 XBD=1600 XBD=1694 XBD=1802 XBD=2015 XBD=2114 XBD=2333 XHG=1364 XHG=1528 XHG=1637 XHG=1728 XHG=1852 XHG=2047 XHG=2143 XHG=2360 YBD=1629 YBD=1634 YBD=1635 YBD=1637 YBD=1630 YBD=1638 YBD=1632 YHG=1598>before YHG=1599>(12, YHG=1600>13, YHG=1599>14). YHG=1598>Finally, YHG=1600>the YHG=1600>following YHG=1601>materials XBD=219 XBD=287 XBD=457 XBD=563 XBD=706 XBD=889 XBD=1080 XBD=1213 XBD=1304 XHG=104 XHG=237 XHG=305 XHG=475 XHG=587 XHG=725 XHG=908 XHG=1100 XHG=1232 YBD=1655 YBD=1663 YBD=1663 YBD=1654 YHG=1626>weeks YHG=1626>by YHG=1626>bathing YHG=1626>with YHG=1626>1/3000 YHG=1625>hydrarg. YHG=1626>perchlor. YHG=1626>lotion YHG=1626>and "" XBD=2526 XBD=1461 XBD=1696 XBD=2011 XBD=2095 XBD=2341 XBD=2422 XHG=1365 XHG=1477 XHG=1711 XHG=2028 XHG=2110 XHG=2355 XHG=2434 YBD=1668 YBD=1669 YBD=1677 YBD=1670 YBD=1680 YHG=1647>were YHG=1639>inoculated YHG=1638>intradermally, YHG=1639>the YHG=1640>inoculation YHG=1639>site YHG=1641>being XBD=167 XHG=889 XBD=400 XBD=458 XBD=640 XBD=768 XBD=872 XBD=953 XBD=1011 XBD=1171 XBD=1224 XBD=1303 XHG=104 XHG=184 XHG=417 XHG=470 XHG=656 XHG=783 XHG=971YBD=1703 XHG=1023 XHG=1187 XHG=1241 YBD=1694 YBD=1694 YBD=1703 YBD=1694 YHG=1666>the YHG=1665>application YHG=1666>of YHG=1666>calamine YHG=1666>lotion YHG=1665>with YHG=1665>2% YHG=1666>of YHG=1665>sulphur YHG=1666>in YHG=1666>the " XBD=1708 XBD=1438 XHG=1367 XHG=1467 YBD=1709 YHG=1677>left YHG=1679>uncovered : " XBD=202 XBD=317 XBD=405 XBD=462 XBD=576 XBD=629 XBD=706 XBD=895 XBD=1019 XHG=105 XHG=218 XHG=334 XHG=422 XHG=473 XHG=591 XHG=643 XHG=721 XHG=910 YBD=1734 YBD=1742 YBD=1733 YBD=1743 YBD=1743YHG=1705>resolving YHG=1706>early YHG=1708>stage YHG=1706>and YHG=1706>of YHG=1707>paste YHG=1705>in YHG=1705>the YHG=1708>stage. " XBD=1736 XBD=1466 XHG=1640 XBD=1624 XHG=1416 YBD=1763 YHG=1734>fluid. XHG=1490 YHG=1735>15. YHG=1734>Vesicle " XBD=235 XBD=438 XBD=585 XBD=701 XBD=796 XBD=873 XBD=1019 XBD=1074 XBD=1148 XBD=1306 XHG=153 XHG=243 XHG=447 XHG=596 XHG=710 XHG=807 XHG=885 XHG=1030 XHG=1081 XHG=1161 YBD=1795 YBD=1796 YBD=1789 YBD=1788 YBD=1789 YBD=1788 YBD=1789 YHG=1758>The YHG=1758>following YHG=1758>figures YHG=1758>show YHG=1758>how YHG=1758>the YHG=1759>extent YHG=1758>of YHG=1758>the YHG=1757>disease " XBD=1468 XBD=1704 XBD=1760 XBD=1889 XHG=1417 XHG=1493 XHG=1720 XHG=1772 XHG=1904 YBD=1803 YBD=1811 YBD=1802 YBD=1810 YHG=1774>16. YHG=1774>Suspension YHG=1774>of YHG=1773>Staph. YHG=1782>pyogenes. " XBD=2080 XBD=270 XHG=627 XBD=355 XBD=554 XBD=614 XBD=861 XHG=105 XHG=287 XHG=372 XHG=570 YBD=1829 YBD=1828 YHG=1798>affected YHG=1799>the YHG=1798>duration YHG=1798>of YHG=1798>treatment:

"" XBD=2525 XBD=1661 XBD=1728 XBD=1919 XBD=1957 XBD=2015 XBD=2079 XBD=2202 XBD=2310 XBD=2392 XBD=2482 XHG=1419 XHG=1675 XHG=1742 XHG=1936 XHG=1973 XHG=2034 XHG=2094 XHG=2217 XHG=2324 XHG=2406 XHG=2493 YBD=1864 YBD=1857 YBD=1865 YBD=1858 YBD=1866 YBD=1859 YHG=1827>Inoculation YHG=1827>by YHG=1826>methods YHG=1827>6 YHG=1827>to YHG=1828>14 YHG=1828>often YHG=1821>gave YHG=1828>rise YHG=1829>only YHG=1830>to XBD=231 XHG=904 XBD=757 XBD=849 XBD=932 XBD=1054 XBD=1138 XBD=1304 XHG=105 XHG=364 XHG=822 XHG=986YBD=1880 XHG=1110 XHG=1195 YBD=1881 YBD=1882 YBD=1883 YBD=1880 YBD=1883 YHG=1855>Extent YHG=1873>........ YHG=1857>+ YHG=1874>.. YHG=1857>++ YHG=1874>.. YHG=1857>+++ " " " " " " " "

XBD=2527 XBD=1394 XBD=1590 XBD=1760 XBD=1827 XBD=1944 XBD=2161 XBD=2253 XBD=2379 XHG=1370 XHG=1420 XHG=1616 XHG=1786 XHG=1855 XHG=1969 XHG=2187 XHG=2280 XHG=2403 YBD=1896 YBD=1897 YBD=1905 YBD=1898 YBD=1899 YHG=1876>a YHG=1867>reaction YHG=1867>similar YHG=1867>to YHG=1867>that YHG=1867>following YHG=1868>the YHG=1877>same YHG=1869>trauma XBD=266 XHG=906 XBD=313 XBD=507 XBD=628 XBD=760 XBD=857 XBD=934 XBD=1045 XBD=1137 XBD=1282 XHG=105 XHG=280 XHG=326 XHG=521 XHG=733 XHG=996YBD=1918 XHG=1111 XHG=1213 YBD=1919 YBD=1922 YBD=1918 YBD=1917 YBD=1918 YHG=1893>Duration YHG=1894>of YHG=1892>treatment YHG=1892>(days) YHG=1892>7-2 YHG=1910>&dquo; YHG=1893>8-5 YHG=1911>.. YHG=1893>10-5 XBD=1540XHG=810 XBD=1655 XBD=1800 XBD=2081 XBD=2180 XBD=2303 XBD=2429 XBD=2525 XHG=1369 XHG=1559 XHG=1674 XHG=1819 XHG=2133 XHG=2200 XHG=2322 XHG=2446 YBD=1937 YBD=1944 YBD=1938 YHG=1906>inflicted YHG=1907>with YHG=1906>sterile YHG=1907>instruments. YHG=1908>In YHG=1917>some YHG=1916>cases, YHG=1908>howXBD=235 XHG=724 XBD=422 XBD=615 XBD=703 XBD=819 XBD=1016 XBD=1097 XBD=1208 XBD=1308 XHG=155 XHG=256 XHG=442 XHG=636 XHG=841YBD=1975 XHG=1036 XHG=1120 XHG=1229 YBD=1976 YBD=1983 YBD=1975 YHG=1946>The YHG=1945>relation YHG=1944>between YHG=1945>the YHG=1945>time YHG=1945>required YHG=1945>for YHG=1954>cure YHG=1944>and XBD=1586 XBD=1820 XBD=1934 XBD=2128 XBD=2194 XBD=2290 XBD=2456 XBD=2527 XHG=1371 XHG=1603 XHG=1837 XHG=1950 XHG=2151 XHG=2214 XHG=2311 XHG=2472 YBD=1984 YBD=1976 YBD=1978 YBD=1977 YHG=1946>ever-and YHG=1946>invariably YHG=1945>with YHG=1947>methods YHG=1947>15 YHG=1947>and YHG=1947>16-the YHG=1947>site XBD=1416 XBD=1689 XBD=1881 XBD=2082 XBD=2220 XBD=2420 XBD=2528 XHG=1372 XHG=1452 XHG=1729 XHG=1923 XHG=2122 XHG=2260 XHG=2454 YBD=2016 YBD=2017 YHG=1986>of YHG=1986>inoculation YHG=1986>showed YHG=1986>marked YHG=1987>local YHG=1986>reaction YHG=1987>with XBD=172 XHG=698 XBD=363 XBD=557 XBD=612 XBD=686 XBD=842 XBD=1021 XBD=1075 XBD=1307 XHG=106 XHG=183 XHG=375 XHG=569 XHG=619 XHG=857YBD=2016 XHG=1032 XHG=1086 YBD=2024 YBD=2015 YBD=2021 YBD=2015 YBD=2021 YHG=1986>the YHG=1986>previous YHG=1985>duration YHG=1985>of YHG=1985>the YHG=1985>disease YHG=1985>(treated YHG=1994>or YHG=1985>untreated) XBD=139 XBD=199 XBD=390 XHG=107 XHG=156 YBD=2056 YBD=2057 YHG=2026>is YHG=2035>as YHG=2026>follows : XBD=1572XHG=215 XBD=1767 XBD=1842 XBD=1938 XBD=2004 XBD=2089 XBD=2320 XBD=2528 XHG=1372 XHG=1590 XHG=1789 XHG=1862 XHG=1960 XHG=2021 XHG=2109 XHG=2338 YBD=2063 YBD=2056 YBD=2057 YBD=2064 YHG=2026>erythema YHG=2026>followed YHG=2026>by YHG=2026>loss YHG=2026>of YHG=2026>the YHG=2026>superficial YHG=2026>epithelium XBD=1417XHG=398 XBD=1478 XBD=1579 XBD=1637 XBD=1732 XBD=1952 XBD=2024 XBD=2142 XBD=2323 XBD=2468 XBD=2528 XHG=1373 XHG=1426 XHG=1490 XHG=1591 XHG=1646 XHG=1745 XHG=1964 XHG=2037 XHG=2156 XHG=2336 XHG=2478 YBD=2103 YBD=2096 YHG=2075>an YHG=2075>area YHG=2066>of YHG=2066>skin YHG=2065>extending YHG=2065>for YHG=2075>some YHG=2066>distance YHG=2065>around YHG=2065>the XBD=268 XBD=351 XBD=523 XHG=108 XHG=316 YBD=2109 YBD=2108 YHG=2084>Duration YHG=2084>of YHG=2082>disease

" XBD=2529 XBD=257 XHG=728 XBD=609 XBD=679 XBD=955 XBD=1255 XBD=1294 XBD=1524 XBD=1719 XBD=1922 XBD=2035 XBD=2101 XBD=2227 XBD=2361 XHG=149 XHG=368 XHG=652 XHG=1002 XHG=1268 XHG=1372 XHG=1576 XHG=1742 XHG=1945 XHG=2059 XHG=2123 XHG=2250 XHG=2376 YBD=2144 YBD=2139 YBD=2139 YBD=2140 YBD=2143 YBD=2135 YBD=2136 YBD=2141 YBD=2144 YHG=2114>(days) YHG=2113>.... YHG=2131>.. YHG=2112>8-14..15-21 YHG=2112>.. 21-28.. YHG=2115>+ YHG=2105>wound. YHG=2106>Oozing YHG=2105>occurred YHG=2105>and, YHG=2105>in YHG=2115>some YHG=2115>cases, YHG=2104>persisted 1-7 29 " XBD=204 XBD=366 XBD=411 XHG=108 XHG=215 XHG=377 YBD=2177 YBD=2176 YHG=2152>Mean YHG=2151>duration YHG=2151>of YHG=2151>treat" XBD=522 XBD=1433XHG=422 XBD=1533 XBD=1600 XBD=1730 XBD=1861 XBD=2217 XBD=2382 XBD=2529 XHG=1372 XHG=1455 XHG=1558 XHG=1623 XHG=1754 XHG=1912 XHG=2240 XHG=2403 YBD=2175 YBD=2183 YBD=2176 YHG=2145>for YHG=2145>two YHG=2154>or YHG=2146>three YHG=2145>days. YHG=2145>Exceptionally, YHG=2145>minute YHG=2145>vesicles " XBD=239 XBD=360 XBD=518 XBD=609 XBD=685 XBD=781 XBD=851 XBD=954 XBD=1030 XBD=1127 XHG=147 XHG=253 XHG=490 XHG=560 XHG=656 XHG=733 XHG=823 XHG=1003 XHG=1079 XHG=1175 YBD=2211 YBD=2204 YBD=2206 YBD=2205 YBD=2205 YBD=2207 YHG=2183>ment YHG=2182>(days) YHG=2180>9-4 YHG=2199>.. YHG=2180>8-5 YHG=2198>.. YHG=2179>7-6 YHG=2199>.. YHG=2180>8,5 YHG=2179>.. 7-6 " XBD=1289 XBD=1584XHG=906 XBD=1726 XBD=1841 XBD=2013 XBD=2215 XBD=2313 XBD=2351 XBD=2433 XBD=2528 XHG=1375 XHG=1601 XHG=1743 XHG=1858 XHG=2032 XHG=2266 XHG=2329 XHG=2367 XHG=2448 YBD=2223 YBD=2215 YBD=2214 YHG=2184>developed YHG=2185>which YHG=2184>later YHG=2185>became YHG=2185>pustules. YHG=2185>In YHG=2194>a YHG=2185>few YHG=2191>cases " XBD=2529 XBD=1498 XBD=1598 XBD=1802 XBD=1930 XBD=1998 XBD=2104 XBD=2221 XBD=2456 XHG=1374 XHG=1521 XHG=1621 XHG=1823 XHG=1954 XHG=2016 XHG=2124 XHG=2242 XHG=2475 YBD=2261 YBD=2254 YBD=2256 YBD=2255 YBD=2259 YBD=2253 YHG=2224>where YHG=2225>two YHG=2223>adjacent YHG=2233>areas YHG=2224>of YHG=2224>skin YHG=2233>were YHG=2223>inoculated, YHG=2231>one XBD=189 XHG=957 XBD=288 XBD=392 XBD=475 XBD=635 XBD=719 XBD=879 XBD=947 XBD=982 XBD=1082 XBD=1187 XBD=1231 XBD=1314 XHG=110 XHG=204 XHG=302 XHG=406 XHG=490 XHG=649 XHG=732 XHG=886 XHG=992YBD=2264 XHG=1092 XHG=1198 XHG=1242 YBD=2266 YBD=2262 YBD=2263 YBD=2270 YBD=2263 YHG=2234>The YHG=2233>fact YHG=2233>that YHG=2233>the YHG=2232>disease YHG=2233>has YHG=2232>existed YHG=2232>for YHG=2242>a YHG=2232>long YHG=2232>time YHG=2232>is YHG=2233>not "" XBD=2533 XBD=1470 XBD=1632 XBD=1753 XBD=1856 XBD=1949 XBD=2086 XBD=2205 XBD=2255 XBD=2480 XHG=1374YBD=2302 XHG=1495 XHG=1658 XHG=1779 XHG=1882 XHG=1975 XHG=2110 XHG=2231 XHG=2280 XHG=2500 YBD=2294YHG=2272>treatment. YBD=2301 YBD=2292 YHG=2264>with YHG=2263>vesicle YHG=2263>fluid YHG=2264>and YHG=2264>the YHG=2264>other YHG=2263>with YHG=2272>a YHG=2263>suspension YHG=2261>of XBD=135 XHG=717 XBD=223 XBD=281 XBD=350 XBD=479 XBD=701 XBD=938 XHG=111 XHG=151 XHG=239 XHG=298 XHG=366 XHG=495 YBD=2304 YBD=2311 YBD=2303 YHG=2282>a YHG=2273>bar YHG=2273>to YHG=2273>its YHG=2272>rapid YHG=2272>successful XBD=1505 XHG=1376 YBD=2341 YHG=2303>Staph. " XBD=2529 XBD=1800 XBD=2001 XBD=2155 XBD=2267 XHG=1733 XHG=1817 XHG=2014 XHG=2172 XHG=2283 YBD=2334 YBD=2340 YHG=2303>the YHG=2303>resulting YHG=2303>lesions YHG=2312>were YHG=2302>indistinguishXBD=285 XHG=741 XBD=346 XBD=454 XBD=642 XBD=713 XBD=909 XBD=1004 XBD=1147 XBD=1313 XHG=159 XHG=312 XHG=374 XHG=483 XHG=670 XHG=938YBD=2343 XHG=1033 XHG=1177 YBD=2342 YBD=2342 YBD=2350 YBD=2343 YHG=2313>When YHG=2313>it YHG=2322>was YHG=2311>decided YHG=2312>to YHG=2312>increase YHG=2312>the YHG=2320>scope YHG=2312>of the " XBD=1462 XBD=1581 XBD=1672 XBD=1864 XBD=2033 XBD=2234 XBD=2348 XBD=2485 XHG=1376 XHG=1481 XHG=1600 XHG=1689 XHG=1914 XHG=2052 XHG=2252 XHG=2365 XHG=2499 YBD=2377 YBD=2374 YBD=2373 YBD=2381 YBD=2372 YHG=2343>able YHG=2352>one YHG=2343>another. YHG=2343>Serial YHG=2343>transfers YHG=2343>from YHG=2351>person YHG=2342>to |>"XBD=2530 XBD=387 XBD=456 XBD=537 XBD=729 XBD=788 XBD=822 XBD=986 XBD=1181 XBD=1315 XBD=1047 XHG=110 XHG=400 XHG=471 XHG=553 XHG=744 XHG=798 XHG=836 XHG=1064 XHG=1198 XHG=1001 YBD=2390 YBD=2383 YBD=2382 YBD=2388 YBD=2390 YBD=2381 YHG=2352>investigation YHG=2352>by YHG=2352>the YHG=2351>addition YHG=2352>of YHG=2361>a YHG=2352>further YHG=2361>cases, YHG=2361>every YHG=2348>30 " XBD=2529 XBD=1515 XBD=1623 XBD=1782 XBD=1863 XBD=1917 XBD=1953 XBD=2037 XBD=2156 XBD=2328 XBD=2411 XHG=1376 XHG=1526 XHG=1637 XHG=1795 XHG=1876 XHG=1930 XHG=1964 XHG=2051 XHG=2167 XHG=2339 XHG=2422 YBD=2421 YBD=2413 YBD=2420 YBD=2412 YHG=2392>person YHG=2392>were YHG=2382>carried YHG=2383>out YHG=2383>in YHG=2392>a YHG=2383>few YHG=2391>cases YHG=2382>without YHG=2391>any YHG=2382>alteraXBD=227 XHG=823 XBD=331 XBD=485 XBD=568 XBD=797 XBD=866 XBD=1056 XBD=1241 XBD=1314 XHG=112 XHG=251 XHG=357 XHG=513 XHG=594 XHG=893YBD=2422 XHG=1083 XHG=1271 YBD=2423 YBD=2428 YBD=2429 YBD=2421 YBD=2427 YBD=2422 YHG=2391>effort YHG=2401>was YHG=2392>made, YHG=2391>by YHG=2391>appealing YHG=2391>to YHG=2390>medical YHG=2391>officers, YHG=2392>to " XBD=2531 XBD=1463 XBD=1519 XBD=1600 XBD=1711 XBD=1772 XBD=1903 XBD=2111 XBD=2240 XBD=2437 XHG=1377 XHG=1477 XHG=1534 XHG=1617 XHG=1728 XHG=1783 XHG=1917 XHG=2127 XHG=2255 XHG=2479 YBD=2451 YBD=2453 YBD=2459 YBD=2452 YBD=2450 YHG=2423>tion YHG=2423>in YHG=2423>the YHG=2422>type YHG=2422>of YHG=2422>lesion YHG=2422>produced YHG=2422>being YHG=2421>observed. YHG=2420>We XBD=243 XHG=925 XBD=383 XBD=458 XBD=541 XBD=679 XBD=819 XBD=897 XBD=992 XBD=1184 XBD=1315 XHG=114 XHG=277 XHG=415 XHG=490 XHG=575 XHG=712 XHG=853 XHG=1027 XHG=1235 YBD=2462 YBD=2468 YBD=2460 YBD=2461 YBD=2461 YBD=2460 YHG=2440>secure YHG=2439>cases YHG=2432>in YHG=2440>an YHG=2431>early YHG=2431>stage YHG=2430>of YHG=2431>the YHG=2430>disease. YHG=2430>The " XBD=2532 XBD=1474 XBD=1703 XBD=1784 XBD=1888 XBD=2047 XBD=2179 XBD=2336 XHG=1377 XHG=1512 XHG=1740 XHG=1821 XHG=1926 XHG=2084 XHG=2215 XHG=2370 YBD=2499 YBD=2492 YBD=2491 YBD=2496 YHG=2470>were YHG=2461>surprised YHG=2462>at YHG=2461>the YHG=2462>rarity YHG=2460>with YHG=2460>which YHG=2459>definitely XBD=341 XHG=646 XBD=419 XBD=614 XBD=977 XBD=1217 XBD=1317 XHG=111 XHG=374 XHG=445 XHG=1007 XHG=1249 YBD=2500 YBD=2508 YBD=2501 YBD=2508 YBD=2500 YHG=2470>limitations YHG=2471>of YHG=2470>hospital YHG=2469>accommodation YHG=2470>permitted YHG=2470>the " XBD=2531 XBD=1560 XBD=1717 XBD=1906 XBD=2026 XBD=2281 XBD=2388 XHG=1378 XHG=1580 XHG=1738 XHG=1925 XHG=2046 XHG=2300 XHG=2407 YBD=2539 YBD=2531 YBD=2530 YBD=2537 YHG=2501>purulent YHG=2501>lesions YHG=2500>resulted YHG=2500>from YHG=2500>inoculation YHG=2500>with YHG=2508>suspenXBD=324 XHG=898 XBD=388 XBD=493 XBD=559 XBD=623 XBD=744 XBD=880 XBD=977 XBD=1106 XBD=1317 XHG=115 XHG=342 XHG=401 XHG=515 XHG=579 XHG=637 XHG=763 XHG=995YBD=2540 XHG=1124 YBD=2548 YBD=2539 YBD=2545 YBD=2540 YBD=2540 YHG=2510>admission YHG=2510>only YHG=2510>14 YHG=2510>of YHG=2509>these YHG=2518>cases, YHG=2510>and YHG=2510>those YHG=2510>admitted " XBD=2533 XBD=1481 XBD=1544 XBD=1686 XBD=1884 XBD=1945 XBD=2057 XBD=2223 XBD=2332 XHG=1379 XHG=1500 XHG=1557 XHG=1704 XHG=1901 XHG=1962 XHG=2073 XHG=2240 XHG=2349 YBD=2572 YBD=2578 YBD=2571 YBD=2570 YBD=2575 YHG=2541>sions YHG=2541>of YHG=2540>Staph. YHG=2548>pyogenes YHG=2550>or YHG=2540>with YHG=2540>morbid YHG=2539>fluid YHG=2539>containing XBD=212 XHG=703 XBD=398 XBD=470 XBD=513 XBD=634 XBD=693 XBD=810 XBD=1007 XBD=1065 XBD=1142 XBD=1316 XHG=115 XHG=232 XHG=418 XHG=488 XHG=531 XHG=649 XHG=827YBD=2583 XHG=1020 XHG=1075 XHG=1157 YBD=2581 YBD=2580 YBD=2579 YBD=2580 YBD=2580 YBD=2585 YHG=2558>were YHG=2549>selected YHG=2559>on YHG=2559>a YHG=2549>basis YHG=2549>of YHG=2548>short YHG=2549>duration YHG=2549>of YHG=2550>the YHG=2549>disease, " XBD=1788 XBD=1446 XBD=1568 XHG=1379 XHG=1463 XHG=1585 YBD=2611 YBD=2618 YHG=2580>the YHG=2589>same YHG=2580>organism. XBD=294 XHG=643 XBD=356 XBD=527 XBD=621 XBD=975 XBD=1186 XBD=1319 XHG=115 XHG=312 XHG=369 XHG=544 XHG=996YBD=2620 XHG=1207 YBD=2626 YBD=2618 YBD=2620 YBD=2619 YHG=2598>presence YHG=2588>of YHG=2589>vesicles YHG=2589>and YHG=2588>accommodation YHG=2589>available YHG=2590>when " XBD=2357 |>" XBD=1508 XBD=1671 XBD=1890 XBD=2012 XBD=2083 XBD=2531 XHG=1429 XHG=1534 XHG=1697 XHG=1915 XHG=2036 XHG=2104 XHG=2373 YBD=2657 YBD=2654 YBD=2650 YBD=2650 YHG=2621>The YHG=2620>lesions YHG=2620>produced YHG=2629>were YHG=2620>of YHG=2618>considerable YHG=2618>.interest : XBD=210 XBD=313 XBD=517 XBD=714 XBD=845 XBD=976 XBD=1174 XBD=1237 XBD=1318 XHG=115 XHG=227 XHG=330 XHG=533 XHG=765 XHG=862 XHG=993 XHG=1192 XHG=1250 YBD=2665 YBD=2666 YBD=2658 YBD=2659 YBD=2659 YBD=2659 YHG=2628>they YHG=2628>first YHG=2628>attended YHG=2628>hospital. YHG=2628>The YHG=2638>mean YHG=2629>duration YHG=2629>of YHG=2629>the " XBD=2531 XBD=1421 XBD=1548 XBD=1676 XBD=1793 XBD=2015 XBD=2168 XBD=2235 XBD=2483 XHG=1380 XHG=1444 XHG=1572 XHG=1699 XHG=1814 XHG=2038 XHG=2192 XHG=2250 XHG=2501 YBD=2697 YBD=2689 YBD=2690 YBD=2688 YHG=2660>in YHG=2668>some YHG=2668>cases YHG=2659>they YHG=2659>presented YHG=2660>points YHG=2659>of YHG=2659>resemblance YHG=2658>to XBD=264 XHG=867 XBD=321 XBD=444 XBD=507 XBD=628 XBD=754 XBD=852 XBD=956 XBD=1048 XBD=1123 XBD=1263 XBD=1318 XHG=119 XHG=278 XHG=335 XHG=462 XHG=523 XHG=642 XHG=767 XHG=970YBD=2699 XHG=1064 XHG=1141 XHG=1295 YBD=2697 YBD=2698 YBD=2699 YBD=2698 YBD=2706 YHG=2667>disease YHG=2667>in YHG=2668>these YHG=2668>14 YHG=2677>cases YHG=2668>when YHG=2668>first YHG=2677>seen YHG=2677>was YHG=2668>6.2 ; YHG=2669>days YHG=2668>4 " XBD=1490 XBD=1560 XBD=1775 XBD=1874 XBD=1953 XBD=2074 XBD=2168 XBD=2355 XBD=2456 XHG=1381 XHG=1515 XHG=1580 XHG=1800 XHG=1896 XHG=1976 XHG=2098 XHG=2192 XHG=2377 XHG=2475 YBD=2735 YBD=2729 YBD=2728 YBD=2733 YHG=2699>those YHG=2698>of YHG=2698>impetigo, YHG=2698>but YHG=2708>we YHG=2707>were YHG=2699>not YHG=2698>satisfied YHG=2698>that YHG=2703>any " XBD=2531 XBD=162 XHG=822 XBD=292 XBD=415 XBD=530 XBD=598 XBD=729 XBD=797 XBD=889 XBD=1055 XBD=1159 XBD=1229 XBD=1319 XHG=117 XHG=183 XHG=316 XHG=441 XHG=555 XHG=623 XHG=754 XHG=915YBD=2738 XHG=1082 XHG=1185 XHG=1251 YBD=2736 YBD=2744 YBD=2737 YBD=2738 YBD=2745 YBD=2738 YBD=2737 YHG=2706>of YHG=2706>them YHG=2715>were YHG=2716>seen YHG=2717>as YHG=2707>early YHG=2716>as YHG=2708>the YHG=2707>second YHG=2708>day YHG=2707>of YHG=2707>the " XBD=1909 XBD=1494 XBD=1559 XBD=1698 XHG=1382 XHG=1511 XHG=1577 XHG=1713 YBD=2768 YBD=2776 YHG=2738>could YHG=2738>be YHG=2738>called YHG=2738>impetigo. XBD=290 XHG=766 XBD=346 XBD=410 XBD=530 XBD=749 XBD=934 XBD=1086 XBD=1126 XBD=1260 XBD=1324 XHG=118 XHG=324 XHG=364 XHG=422 XHG=547 XHG=987YBD=2777 XHG=1104 XHG=1148 XHG=1279 YBD=2774 YBD=2775 YBD=2776 YBD=2783 YBD=2785 YBD=2777YHG=2747>vesicles. YBD=2783 YHG=2746>disease YHG=2745>6 YHG=2745>of YHG=2746>them YHG=2746>presented YHG=2747>Only YHG=2747>3 YHG=2747>(none YHG=2746>of ; " XBD=1317 XBD=226 XHG=826 XBD=303 XBD=407 XBD=631 XBD=789 XBD=978 XBD=1088 XHG=117 XHG=261 XHG=339 XHG=444 XHG=666 XHG=1014YBD=2824 XHG=1125 YBD=2814 YBD=2815 YBD=2823 YBD=2816YHG=2786>yielded YBD=2824 YHG=2784>them YHG=2784>in YHG=2784>the YHG=2785>vesicular YHG=2786>stage) YHG=2786>Str. YHG=2794>pyogenes. " XBD=2096 XHG=1859 YBD=2854 YHG=2830>DISCUSSION XBD=274 XHG=915 XBD=333 XBD=411 XBD=530 XBD=639 XBD=809 XBD=901 XBD=985 XBD=1097 XBD=1261 XBD=1321 XHG=119 XHG=288 XHG=343 XHG=425 XHG=543 XHG=652 XHG=822 XHG=998YBD=2855 XHG=1110 XHG=1276 YBD=2853 YBD=2854 YBD=2856 YBD=2856 YBD=2855 YHG=2823>Several YHG=2823>of YHG=2823>the YHG=2833>cases YHG=2824>with YHG=2825>vesicles YHG=2825>had YHG=2825>not YHG=2825>been YHG=2826>treated YHG=2825>at

pyogenes,

... -

XBD=170 XHG=633 XBD=321 XBD=552 XBD=614 XBD=814 XHG=103 XHG=190 XHG=341 XHG=571 YBD=2893 YHG=2863>all YHG=2862>before YHG=2863>admission YHG=2864>to "" XBD=2533 XBD=1554 XBD=1630 XBD=1893 XBD=1992 XBD=2284 XBD=2355 XBD=2458 XHG=1430YBD=2901 XHG=1574 XHG=1651 XHG=1914 XHG=2011 XHG=2303 XHG=2373 XHG=2474 YBD=2907YHG=2864>hospital. YBD=2915 YBD=2908 YBD=2909 YHG=2878>When YHG=2877>commenced YHG=2877>this YHG=2877>investigation YHG=2887>we YHG=2887>were YHG=2875>still |>" " XBD=248 XBD=474 XBD=656 XBD=747 XBD=962 XBD=1028 XBD=1108 XBD=1318 XBD=121 XHG=168 XHG=261 XHG=487 XHG=668 XHG=760 XHG=975 XHG=1041 XHG=1122 XHG=115 YBD=2932 YBD=2940 YBD=2933 YBD=2941 YBD=2940 YBD=2929 YBD=2933 YBD=2941 YHG=2902>The YHG=2902>treatment YHG=2902>adopted YHG=2912>was YHG=2903>suggested YHG=2903>by YHG=2923>. YHG=2903>the YHG=2912>compara" XBD=1504 XBD=1600 XBD=1817 XBD=1893 XBD=2073 XBD=2327 XBD=2430 XBD=2533 XHG=1381 XHG=1534 XHG=1632 XHG=1849 XHG=1919 XHG=2104 XHG=2354 XHG=2457 YBD=2946 YBD=2947 YBD=2948 YHG=2916>under YHG=2917>the YHG=2917>influence YHG=2916>of YHG=2916>various YHG=2917>authorities YHG=2918>who YHG=2917>have " XBD=200 XBD=371 XBD=438 XBD=667 XBD=741 XBD=872 XBD=1015 XBD=1107 XHG=118 XHG=221 XHG=393 XHG=455 XHG=687 XHG=893 XHG=1067 XHG=1128 YBD=2972 YBD=2971 YBD=2979 YBD=2980 YBD=2972 YBD=2973 YHG=2942>tive YHG=2950>success YHG=2942>of YHG=2941>treatment YHG=2942>by YHG=2944>paste YHG=2943>alone. YHG=2942>It YHG=2941>consisted " XBD=1321 XBD=1512XHG=761 XBD=1636 XBD=1854 XBD=1922 XBD=2098 XBD=2188 XBD=2246 XBD=2532 XHG=1382 XHG=1548 XHG=1671 XHG=1888 XHG=1959 XHG=2133 XHG=2222 XHG=2280 YBD=2987 YBD=2985 YBD=2988 YBD=2993 YBD=2986 YBD=2994 YHG=2956>stated YHG=2956>that YHG=2956>impetigo YHG=2955>is YHG=2955>caused YHG=2956>by YHG=2965>a YHG=2957>streptococcus. "" XBD=1321 XBD=161 XBD=410 XBD=649 XBD=781 XBD=887 XBD=926 XBD=1027 XBD=1108 XBD=1200 XHG=118 XHG=171 XHG=421 XHG=659 XHG=794 XHG=901 XHG=938 XHG=1041 XHG=1121 XHG=1213 YBD=3012 YBD=3020 YBD=3013 YBD=3012 YHG=2981>in YHG=2980>mechanical YHG=2980>removal-of YHG=2981>crusts YHG=2991>once YHG=2991>a YHG=2982>day, YHG=2982>the YHG=2990>raw XBD=1537 XHG=2504 XBD=1698 XBD=1761 XBD=1915 XBD=2047 XBD=2170 XBD=2307 XBD=2486 XBD=2536 XHG=1384 YBD=3026 XHG=1560 XHG=1720 XHG=1784 XHG=1937 XHG=2071 XHG=2195 XHG=2327 YBD=3033 YHG=2991>areas YBD=3025 YBD=3032 YBD=3027 YHG=2995>Several YHG=3004>papers YHG=2996>in YHG=2995>recent YHG=3003>years YHG=2996>have YHG=2993>given YHG=2996>accounts YHG=2994>of " XBD=287 XBD=428 XBD=614 XBD=733 XBD=831 XBD=982 XBD=1209 XHG=119 XHG=312 XHG=453 XHG=638 XHG=759 XHG=1008 XHG=1259 YBD=3059 YBD=3051 YBD=3050 YBD=3058 YBD=3052 YBD=3059 YBD=3051 YHG=3021>exposed YHG=3020>being YHG=3020>covered YHG=3020>with YHG=3021>dry YHG=3021>sterile YHG=3021>dressings. YHG=3021>No " XBD=1321 XBD=1537XHG=856 XBD=1605 XBD=1765 XBD=2041 XBD=2166 XBD=2257 XBD=2408 XBD=2466 XBD=2534 XHG=1383 XHG=1563 XHG=1631 XHG=1791 XHG=2066 XHG=2191 XHG=2281 XHG=2421 XHG=2484 YBD=3072 YBD=3065 YBD=3066 YBD=3076 YBD=3067 YHG=3035>failures YHG=3036>to YHG=3035>isolate YHG=3034>streptococci YHG=3035>from YHG=3036>the YHG=3035>lesions YHG=3037>of YHG=3037>the " XBD=218 XBD=472 XBD=567 XBD=786 XBD=905 XBD=989 XBD=1115 XBD=1230 XBD=1322 XHG=119 XHG=236 XHG=488 XHG=586 XHG=803 XHG=922 XHG=1008 XHG=1132 XHG=1250 YBD=3091 YBD=3097 YBD=3090 YBD=3091 YBD=3097 YHG=3060>local YHG=3059>medication YHG=3069>was YHG=3059>employed YHG=3060>until YHG=3061>the YHG=3070>areas YHG=3070>were YHG=3061>dry "" XBD=2534 XBD=1567 XBD=1641 XBD=1835 XBD=2046 XBD=2174 XBD=2377 XBD=2469 XHG=1383 XHG=1597 XHG=1665 XHG=1864 XHG=2074 XHG=2202 XHG=2404 XHG=2491 YBD=3111 YBD=3110 YBD=3104 YBD=3112 YBD=3105 YBD=3106 YHG=3074>majority YHG=3074>of YHG=3075>patients YHG=3073>suffering YHG=3074>from YHG=3074>impetigo YHG=3069>and YHG=3083>we XBD=199 XHG=800 XBD=373 XBD=439 XBD=593 XBD=789 XBD=922 XBD=1147 XBD=1321 XHG=120 XHG=210 XHG=384 XHG=448 XHG=604 XHG=934YBD=3134 XHG=1155 YBD=3130 YBD=3138 YBD=3137 YBD=3129 YBD=3136 YBD=3136 YHG=3099>and YHG=3099>covered YHG=3099>by YHG=3099>loosely YHG=3099>adherent YHG=3099>scabs, YHG=3099>indicating YHG=3100>healing, " XBD=2533 XBD=1527 XBD=1589 XBD=1673 XBD=1862 XBD=1937 XBD=2071 XBD=2162 XBD=2228 XBD=2347 XHG=1384 XHG=1548 XHG=1611 XHG=1693 XHG=1880 XHG=1959 XHG=2092 XHG=2181 XHG=2248 XHG=2366 YBD=3143 YBD=3145 YHG=3113>wished YHG=3114>to YHG=3122>see YHG=3113>whether YHG=3122>we YHG=3113>could YHG=3114>not YHG=3113>be YHG=3123>more YHG=3113>successful "" XBD=1323 XBD=292 XBD=424 XBD=522 XBD=637 XBD=810 XBD=889 XBD=982 XBD=1045 XBD=1141 XBD=1259 XHG=122 XHG=312 XHG=444 XHG=543 XHG=657 XHG=829 XHG=1001 XHG=1064 XHG=1163 XHG=1279 YBD=3177 YBD=3169 YBD=3175 YBD=3167 YBD=3168 YBD=3169 YBD=3175 YBD=3168 YHG=3139>Lassar’s YHG=3139>paste YHG=3148>was YHG=3139>then YHG=3137>applied YHG=3138>for YHG=3147>one YHG=3147>or YHG=3139>two YHG=3138>days YHG=3139>to XBD=1483XHG=909 XBD=1564 XBD=1736 XBD=1793 XBD=1985 XBD=2105 XBD=2175 XBD=2283 XBD=2368 XBD=2425 XBD=2534 XHG=1385 XHG=1497 XHG=1579 XHG=1751 XHG=1806 XHG=2000 XHG=2119 XHG=2190 XHG=2296 XHG=2381 XHG=2439 YBD=3181 YBD=3189 YBD=3182 YBD=3183 YBD=3184 YHG=3152>than YHG=3151>the YHG=3152>authors YHG=3152>in YHG=3152>isolating YHG=3152>what YHG=3161>we YHG=3152>then YHG=3152>had YHG=3162>no YHG=3153>doubt " XBD=1979 XBD=312 XBD=399 XBD=599 XBD=742 XBD=854 XBD=950 XBD=1127 XBD=1197 XBD=1324 XHG=124 XHG=331 XHG=418 XHG=617 XHG=791 XHG=872 XHG=968 XHG=1145 XHG=1215 YBD=3216 YBD=3208 YBD=3214 YBD=3207 YBD=3207 YBD=3207 YBD=3208 YHG=3178>complete YHG=3178>the YHG=3178>cosmetic YHG=3177>effect. YHG=3177>By YHG=3177>this YHG=3177>method YHG=3178>all YHG=3177>these " |>" XBD=1464 XBD=1547 XBD=1761 XBD=2607 XHG=1386 XHG=1481 XHG=1565 XHG=1778 XHG=2600 YBD=3221 YBD=3222 YBD=3229 YBD=3201 YHG=3200>was YHG=3191>the YHG=3192>causative YHG=3191>organism. YHG=3194>’ " XBD=2556 XBD=294 XHG=871 XBD=406 XBD=535 XBD=590 XBD=703 XBD=738 XBD=794 XBD=855 XBD=967 XBD=1110 XBD=1183 XBD=1323 XHG=123 XHG=308 XHG=420 XHG=549 XHG=602 XHG=717 XHG=753 XHG=811 XHG=984YBD=3253 XHG=1123 XHG=1199 YBD=3254 YBD=3248 YBD=3247 YBD=3246 YBD=3245 YBD=3252 YBD=3246 YBD=3254 YHG=3217>patients YHG=3226>were YHG=3217>cured YHG=3217>in YHG=3217>from YHG=3215>5 YHG=3216>to YHG=3216>17 YHG=3215>days YHG=3217>(mean YHG=3217>9,8 YHG=3216>days). " XBD=1516 XBD=1666 XBD=1786 XBD=1887 XBD=1957 XBD=2068 XBD=2132 XBD=2250 XBD=2449 XHG=1438 XHG=1529 XHG=1681 XHG=1799 XHG=1900 XHG=1971 XHG=2083 XHG=2147 XHG=2265 XHG=2461 YBD=3260 YBD=3261 YBD=3262 YBD=3263 YHG=3230>Our YHG=3230>results YHG=3231>show YHG=3231>that YHG=3239>we YHG=3239>were YHG=3240>no YHG=3240>more YHG=3231>successful YHG=3233>than " XBD=175 XBD=403 XBD=515 XBD=784 XBD=968 XBD=1140 XHG=126 XHG=208 XHG=438 XHG=550 XHG=818 XHG=1004 XHG=1173 YBD=3285 YBD=3286 YBD=3287 YBD=3293 YBD=3290 YBD=3292 YHG=3256>In YHG=3256>confluent YHG=3257>and YHG=3255>progressive YHG=3255>lesions, YHG=3255>oozing YHG=3255>usually " XBD=1326 |>" XBD=1516 XBD=1585 XBD=1790 XBD=2067 XBD=2193 XBD=2393 XBD=2533 XBD=2606 XHG=1388 XHG=1544 XHG=1610 XHG=1816 XHG=2094 XHG=2220 XHG=2414 XHG=2604 YBD=3299 YBD=3305 YBD=3306 YBD=3298 YBD=3307 YBD=3301 YBD=3283 YHG=3269>others YHG=3269>in YHG=3269>isolating YHG=3269>streptococci YHG=3270>from YHG=3270>impetigo YHG=3270>lesions. YHG=3275>’ " XBD=2534 XBD=334 XHG=861 XBD=410 XBD=450 XBD=510 XBD=549 XBD=664 XBD=757 XBD=847 XBD=986 XBD=1061 XBD=1120 XBD=1227 XBD=1285 XBD=1325 XHG=126 XHG=349 XHG=428 XHG=468 XHG=528 XHG=568 XHG=680 XHG=773 XHG=1000 XHG=1078 XHG=1137 XHG=1243 XHG=1303 YBD=3333 YBD=3325 YBD=3324 YBD=3331 YBD=3330 YBD=3323 YHG=3295>continued YHG=3296>for YHG=3296>4 YHG=3304>or YHG=3295>5 YHG=3295>days YHG=3295>and YHG=3294>but YHG=3294>rarely YHG=3294>for YHG=3303>as YHG=3294>long YHG=3302>as YHG=3294>8 " XBD=1510 XBD=1705 XBD=1850 XBD=1926 XBD=2045 XBD=2273 XBD=2462 XHG=1388 XHG=1528 XHG=1725 XHG=1869 XHG=1945 XHG=2066 XHG=2293 XHG=2477 YBD=3344 YBD=3337 YBD=3338 YBD=3339 YBD=3340 YHG=3308>Using YHG=3307>methods YHG=3308>which YHG=3317>we YHG=3308>have YHG=3308>convinced YHG=3309>ourselves YHG=3307>will " XBD=236 YBD=3371 YHG=3334>days. " XBD=1515XHG=128 XBD=1602 XBD=1801 XBD=1867 XBD=2134 XBD=2251 XBD=2374 XBD=2471 XBD=2534 XHG=1389 XHG=1537 XHG=1624 XHG=1823 XHG=1883 XHG=2156 XHG=2270 XHG=2392 XHG=2487 YBD=3383 YBD=3376 YBD=3377 YBD=3385 YBD=3378 YHG=3346>reveal YHG=3346>the YHG=3355>presence YHG=3347>of YHG=3346>streptococci YHG=3356>even YHG=3347>when YHG=3348>they YHG=3356>are " XBD=886 XHG=571 YBD=3403 YHG=3379>EXPERIMENTAL " XBD=2472 XBD=2535 XHG=2483 XBD=1632 XBD=1924 XBD=1992 XBD=2118 XBD=2310 XBD=2376 XHG=1390 YBD=3415 XHG=1646 XHG=1939 XHG=2007 XHG=2132 XHG=2324 XHG=2388 YBD=3422 YHG=3386>not YBD=3420 YBD=3416 YHG=3385>enormously YHG=3385>outnumbered YHG=3385>by YHG=3385>other YHG=3385>bacteria, YHG=3395>we YHG=3386>have XBD=1511 XBD=1643 XBD=1877 XBD=2057 XBD=2123 XBD=2214 XBD=2409 XBD=2466 XHG=1389 XHG=1537 XHG=1669 XHG=1902 XHG=2082 XHG=2148 XHG=2238 XHG=2429 XHG=2483 YBD=3461 YBD=3462 YBD=3455 YBD=3454 YHG=3424>found YHG=3425>these YHG=3424>organisms YHG=3425>present YHG=3424>in YHG=3425>the YHG=3424>majority YHG=3425>of YHG=3432>our " XBD=2534 XBD=296 XHG=571 XBD=498 XBD=555 XBD=751 XBD=946 XBD=1057 XBD=1196 XBD=1328 XHG=763 XHG=176 XHG=310 XHG=513 XHG=960YBD=3464 XHG=1071 XHG=1247 YBD=3465 YBD=3458 YBD=3455 YHG=3426>Many YHG=3427>attempts YHG=3428>to YHG=3427>transmit YHG=3425>impetigo YHG=3434>were YHG=3425>made. YHG=3425>The

" XBD=2531 XBD=1507 XBD=1636 XBD=1757 XBD=1952 XBD=2251 XBD=2382 XBD=2462 XHG=1391 XHG=1559 XHG=1656 XHG=1778 XHG=1971 XHG=2269 XHG=2398 XHG=2477 YBD=3494 YBD=3500 YBD=3493 YHG=3473>cases. YHG=3463>The YHG=3464>most YHG=3472>common YHG=3464>streptococcus YHG=3463>found YHG=3472>was YHG=3463>Str. XBD=324 XHG=759 XBD=464 XBD=511 XBD=603 XBD=744 XBD=885 XBD=1047 XBD=1129 XBD=1328 XHG=128 XHG=339 XHG=479 XHG=526 XHG=618 XHG=901YBD=3496 XHG=1063 XHG=1144 YBD=3497 YBD=3504 YBD=3501 YBD=3495YHG=3465>would YHG=3466>materials YHG=3467>which YHG=3468>it YHG=3476>was YHG=3467>hoped YHG=3473>convey YHG=3464>the YHG=3465>infection

i

547

" XBD=2523 XBD=1461 XBD=1617 XBD=1683 XBD=2018 XBD=2080 XBD=2167 XBD=2371 XBD=2437 XHG=1383 XHG=1482 XHG=1639 XHG=1699 XHG=2039 XHG=2101 XHG=2187 XHG=2392 XHG=2455 YBD=237 YBD=236 YBD=243 YBD=235 YHG=207>The YHG=207>failure YHG=206>sulphonamides, YHG=206>in YHG=207>the YHG=206>majority YHG=206>of YHG=214>our XBD=274 XHG=854 XBD=372 XBD=449 XBD=618 XBD=732 XBD=825 XBD=981 XBD=1101 XBD=1171 XBD=1273 XHG=107 XHG=296 XHG=394 XHG=472 XHG=643 XHG=759 XHG=1010YBD=237 XHG=1124 XHG=1200 YBD=248 YBD=238 YBD=236 YBD=244YHG=207>others YHG=216>pyogenes, YHG=207>and YHG=216>we YHG=207>believe YHG=207>that YHG=207>the YHG=217>may YHG=208>be YHG=207>dis-

" " " " " " " " " "

XBD=2523XHG=906 XBD=1449 XBD=1510 XBD=1663 XBD=1894 XBD=1975 XBD=2085 XBD=2275 XBD=2334 XBD=2440 XHG=1334 XHG=1468 XHG=1527 XHG=1679 XHG=1910 XHG=1992 XHG=2102 XHG=2292 XHG=2352 XHG=2457 YBD=281 YBD=276 YBD=283 YBD=282 YBD=275 YBD=274 YHG=255>cases, YHG=246>reduce YHG=245>materially YHG=245>the YHG=245>time YHG=244>required YHG=246>to YHG=253>cure YHG=244>the XBD=278 XBD=368 XBD=476 XBD=544 XBD=779 XBD=887 XBD=978 XBD=1178 XBD=1275 XHG=108 XHG=328 XHG=385 XHG=496 XHG=565 XHG=799 XHG=999YBD=276 XHG=1197 YBD=286 YBD=284 YBD=277 YBD=284 YHG=244>regarded. YHG=247>It YHG=255>may YHG=247>be YHG=246>contended YHG=247>that YHG=246>Str. YHG=255>pyogenes YHG=255>was XBD=1478XHG=824 XBD=1532 XBD=1604 XBD=1837 XBD=2057 XBD=2228 XBD=2323 XBD=2524 XHG=1334 XHG=1500 XHG=1554 XHG=1625 XHG=1858 XHG=2078 XHG=2249 XHG=2344 YBD=314 YBD=315 YBD=320 YBD=313 YBD=321 YHG=285>disease YHG=285>is YHG=294>an YHG=285>additional YHG=284>argument YHG=284>against YHG=283>Str. YHG=291>pyogenes XBD=165 XBD=333 XBD=451 XBD=540 XBD=742 XBD=807 XBD=893 XBD=1017 XBD=1197 XBD=1274 XHG=109 XHG=182 XHG=352 XHG=472 XHG=560 XHG=764 XHG=913YBD=315 XHG=1038 XHG=1217 YBD=320 YBD=319 YBD=317 YBD=316 YBD=322 YBD=315 YBD=316 YHG=289>not YHG=286>isolated YHG=286>from YHG=286>the YHG=285>majority YHG=285>of YHG=294>our YHG=294>cases YHG=285>because YHG=295>we XBD=1448 XBD=1535 XBD=1668 XBD=1734 XBD=1944 XBD=2183 XBD=2294 XBD=2437 XBD=2523 XHG=1333 XHG=1469 XHG=1559 XHG=1690 XHG=1750 XHG=1995 XHG=2205 XHG=2315 XHG=2459 YBD=360 YBD=354 YBD=361 YBD=353 YBD=352 YHG=324>being YHG=324>the YHG=333>cause YHG=324>of YHG=324>impetigo. YHG=322>Provided YHG=323>that YHG=323>crusts YHG=331>are XBD=285 XHG=827 XBD=450 XBD=558 XBD=727 XBD=798 XBD=951 XBD=1047 XBD=1274 XHG=108 XHG=315 XHG=480 XHG=589 XHG=756 XHG=981YBD=354 XHG=1079 YBD=360 YBD=362 YBD=355 YBD=354 YHG=326>examined YHG=325>chiefly YHG=325>late YHG=325>lesions YHG=325>in YHG=324>which YHG=325>the YHG=324>causative XBD=1523XHG=760 XBD=1736 XBD=1986 XBD=2192 XBD=2424 XBD=2524 XHG=1334 XHG=1546 XHG=1760 XHG=2008 XHG=2214 XHG=2447 YBD=398 YBD=393 YBD=392 YBD=399 YBD=391 YHG=363>regularly YHG=363>removed, YHG=364>extraneous YHG=362>infection YHG=361>prevented YHG=361>and XBD=276 XBD=368 XBD=481 XBD=672 XBD=744 XBD=827 XBD=1061 XBD=1273 XHG=109 XHG=292 XHG=385 XHG=497 XHG=690 XHG=845 XHG=1079 YBD=405 YBD=395 YBD=394 YBD=401 YBD=393 YBD=393 YBD=400 YHG=367>organism YHG=365>had YHG=365>been YHG=363>replaced YHG=363>by YHG=364>the YHG=371>commoner YHG=363>staphyloXBD=1527 XBD=1767 XBD=1953 XBD=2067 XBD=2182 XBD=2283 XBD=2524 XHG=1333 XHG=1538 XHG=1779 XHG=1966 XHG=2080 XHG=2195 XHG=2295 YBD=432 YBD=438 YBD=431 YHG=402>irritating YHG=402>medication YHG=402>avoided, YHG=402>most YHG=410>cases YHG=409>cure YHG=401>themselves XBD=233 XHG=838 XBD=359 XBD=482 XBD=530 XBD=635 XBD=707 XBD=821 XBD=969 XBD=1036 XBD=1217 XBD=1275 XHG=108 XHG=283 XHG=374 XHG=497 XHG=547 XHG=650 XHG=724 XHG=985YBD=431 XHG=1051 XHG=1234 YBD=438 YBD=435 YBD=441 YBD=433 YBD=432 YBD=431 YHG=415>coccus. YHG=405>Our YHG=404>reply YHG=403>is YHG=403>that YHG=412>we YHG=403>have YHG=403>shown YHG=411>an YHG=402>increase YHG=402>in XBD=1375 XBD=1438 XBD=1553 XBD=1614 XBD=1714 XBD=1874 XBD=1933 XBD=2066 XBD=2161 XBD=2283 XBD=2368 XBD=2523 XHG=1333 XHG=1395 XHG=1458 XHG=1573 XHG=1631 XHG=1765 XHG=1891 XHG=1949 XHG=2083 XHG=2179 XHG=2301 XHG=2385 YBD=477 YBD=471 YBD=478 YBD=469 YBD=470 YHG=440>in YHG=441>10 YHG=441>days YHG=450>or YHG=442>less. YHG=441>Since YHG=442>in YHG=450>many YHG=441>late YHG=449>cases YHG=440>the YHG=440>lesions XBD=160 XHG=810 XBD=397 XBD=466 XBD=592 XBD=786 XBD=882 XBD=1088 XBD=1155 XBD=1274 XHG=107 XHG=182 XHG=422 XHG=488 XHG=617 XHG=909YBD=471 XHG=1112 XHG=1181 YBD=477 YBD=482 YBD=472 YBD=478 YBD=478 YHG=446>the YHG=443>proportion YHG=442>of YHG=451>cases YHG=441>yielding YHG=441>Str. YHG=436>pyogenes YHG=450>as YHG=440>time XBD=1489XHG=842 XBD=1676 XBD=1789 XBD=2080 XBD=2155 XBD=2321 XBD=2431 XBD=2523 XHG=1333 XHG=1509 XHG=1695 XHG=1902 XHG=2100 XHG=2175 XHG=2341 XHG=2451 YBD=510 YBD=518 YHG=479>become YHG=480>infected YHG=480>with YHG=488>pyogenes YHG=488>we YHG=479>believe YHG=479>that YHG=488>one XBD=315 XBD=421 XBD=540 XBD=634 XBD=815 XBD=980 XBD=1162 XBD=1274 XHG=106 XHG=345 XHG=450 XHG=568 XHG=664 XHG=1009 XHG=1195 YBD=524 YBD=511 YBD=510 YBD=509 YBD=509 YBD=513 YHG=482>progressed, YHG=481>and YHG=481>that YHG=481>the YHG=480>earliest YHG=480>lesions YHG=479>studied YHG=479>(the XBD=1379 XBD=1469 XBD=1804 XBD=1984 XBD=2148 XBD=2240 XBD=2296 XBD=2523 XHG=1334 XHG=1403 XHG=1498 XHG=1833 XHG=2011 XHG=2172 XHG=2261 XHG=2320 YBD=547 YBD=557 YBD=556 YBD=554 YBD=548 YBD=555 YHG=518>of YHG=518>the YHG=518>sulphonamides YHG=520>applied YHG=519>locally YHG=520>(or, YHG=519>if YHG=518>preferred, XBD=255 XHG=698 XBD=420 XBD=506 XBD=547 XBD=681 XBD=991 XHG=105 XHG=272 XHG=436 XHG=523 XHG=563 YBD=557 YBD=558 YBD=549 YBD=555 YBD=556 YHG=522>vesicles) YHG=520>yielded YHG=520>not YHG=529>a YHG=519>single YHG=520>streptococcus. XBD=1604XHG=651 XBD=1760 XBD=1808 XBD=1950 XBD=2122 XBD=2212 XBD=2524 XHG=1334 XHG=1628 XHG=1777 XHG=1827 XHG=1973 XHG=2146 XHG=2237 YBD=595 YBD=596 YBD=588 YBD=594 YHG=557>administered YHG=558>orally) YHG=559>useful YHG=559>against YHG=559>the YHG=557>complications XBD=174 XBD=387 XBD=583 XBD=641 XBD=721 XBD=1007 XBD=1126 XBD=1171 XBD=1275 XHG=143 XHG=185 XHG=403 XHG=597 XHG=735 XHG=1021 XHG=1139 XHG=1186 YBD=592 YBD=598 YBD=588 YBD=587 YBD=595 YBD=586 YBD=587 YHG=562>A YHG=560>legitimate YHG=559>criticism YHG=558>of YHG=567>our YHG=557>experimental YHG=557>work YHG=557>is YHG=557>that XBD=149 XBD=227 XBD=314 XBD=521 XBD=707 XBD=771 XBD=858 XBD=1067 XBD=1187 XBD=1274 XHG=105 XHG=167 XHG=245 XHG=330 XHG=541 XHG=727 XHG=878 XHG=1118 XHG=1207 YBD=631 YBD=629 YBD=628 YBD=627 YBD=633 YBD=626 YHG=610>we YHG=599>did YHG=598>not YHG=598>inoculate YHG=596>cultures YHG=596>of YHG=605>pyogenes. YHG=596>We YHG=596>did XBD=1379XHG=786 XBD=1470 XBD=1645 XBD=1802 XBD=1928 XBD=2107 XBD=2201 XBD=2377 XBD=2521 XHG=1334YBD=626 XHG=1404 XHG=1502 XHG=1675 XHG=1832 XHG=1956 XHG=2136 XHG=2233 XHG=2407 YBD=635YHG=596>Str. YBD=627 YHG=595>of YHG=596>the YHG=596>disease YHG=597>rather YHG=598>than YHG=598>against YHG=597>the YHG=597>disease YHG=595>itself.

Str.

" XBD=2520 XBD=1415 XBD=1640 XBD=1683 XBD=1755 XBD=1790 XBD=1958 XBD=2014 XBD=2230 XBD=2312 XHG=1336 XHG=1426 XHG=1652 XHG=1695 XHG=1767 XHG=1800 XHG=1971 XHG=2022 XHG=2242 XHG=2324 YBD=664 YBD=671 YBD=665 YBD=666 YHG=635>Our YHG=635>preference YHG=636>is YHG=636>for YHG=645>a YHG=636>method YHG=637>of YHG=637>treatment YHG=636>not YHG=635>described XBD=161 XHG=842 XBD=336 XBD=381 XBD=602 XBD=656 XBD=749 XBD=828 XBD=983 XBD=1274 XHG=104 XHG=173 XHG=348 XHG=394 XHG=615 XHG=671 XHG=762 XHG=998YBD=665 YBD=670 YBD=668 YBD=666 YBD=673 YBD=673 YHG=640>not YHG=637>consider YHG=637>it YHG=636>justifiable YHG=636>to YHG=636>risk YHG=636>the YHG=636>serious YHG=644>consequences

" XBD=2371 XBD=2523XHG=622 XBD=210 XBD=318 XBD=375 XBD=608 XBD=797 XBD=1024 XBD=1275 XBD=1374 XBD=1470 XBD=1888 XBD=2071 XBD=2135 XBD=2273 XHG=104 XHG=223 XHG=333 XHG=391 XHG=813YBD=704 XHG=1039 XHG=1332 XHG=1393 XHG=1490 XHG=1909 XHG=2091 XHG=2151 XHG=2294 XHG=2390 YBD=708 YBD=706 YBD=705 YBD=712 YBD=704 YBD=703 YBD=704 YBD=711 YBD=712 YBD=705 YBD=706 YHG=677>which YHG=677>have YHG=685>so YHG=675>commonly YHG=674>followed YHG=674>accidental YHG=674>inoculation YHG=674>in YHG=673>this YHG=674>paper-mechanical YHG=675>clearing YHG=676>of YHG=677>crusts YHG=675>and YHG=674>liberal XBD=182 XHG=837 XBD=271 XBD=488 XBD=818 XBD=933 XBD=982 XBD=1178 XBD=1273 XHG=948 XHG=103 XHG=197 XHG=287 XHG=538 XHG=995YBD=742 XHG=1195 YBD=747 YBD=745 YBD=751 YBD=748 YBD=743 YBD=751 YHG=716>with YHG=715>this YHG=714>organism. YHG=713>Furthermore, YHG=723>even YHG=714>impetigo YHG=713>had " XBD=2522 XBD=1489 XBD=1546 XBD=1618 XBD=1793 XBD=1911 XBD=2016 XBD=2344 XHG=1333 XHG=1501 XHG=1554 XHG=1631 XHG=1804 XHG=1923 XHG=2028 XHG=2356 YBD=750YHG=713>if YBD=743 YBD=751 YBD=744 YBD=752 YBD=753 YHG=713>dusting YHG=714>of YHG=713>the YHG=714>affected YHG=715>parts YHG=714>with YHG=715>sulphanilamide YHG=714>powder, Str. " XBD=2090 XBD=1031 XBD=1128 XBD=1274 XBD=1486 XBD=1667 XBD=1706 XBD=1899 XBD=1958 XHG=840YBD=783 XHG=1051 XHG=1147 XHG=1332 XHG=1503 XHG=1683 XHG=1723 XHG=1914 XHG=1969 YBD=790 YBD=782 YBD=783 YBD=790 YHG=761>pyogenes, YHG=753>this YHG=753>would YHG=751>applied YHG=753>without YHG=762>a YHG=753>covering YHG=753>of YHG=755>paste. XBD=248 XHG=635 XBD=364 XBD=617 XBD=730 XHG=102 XHG=266 XHG=382 YBD=786 YHG=753>resulted YHG=753>from YHG=753>inoculation YHG=753>with " XBD=1273 XBD=185 XHG=621 XBD=352 XBD=473 XBD=593 XBD=699 XBD=1010 XBD=1131 XHG=101 XHG=212 XHG=383 XHG=503 XHG=729YBD=821 XHG=1039 XHG=1160 YBD=824 YBD=829 YBD=828 YBD=828 YBD=829 YBD=822 YHG=795>have YHG=792>proved YHG=792>only YHG=792>that YHG=792>this YHG=792>streptococcus YHG=801>may YHG=800>cause

" XBD=1274 XBD=288 XHG=951 XBD=348 XBD=485 XBD=569 XBD=680 XBD=837 XBD=938 XBD=983 XBD=1028 XHG=100 XHG=315 XHG=359 XHG=498 XHG=581 XHG=693 XHG=851 XHG=996YBD=860 XHG=1042 YBD=869 YBD=868 YBD=860 YBD=868 YHG=832>impetigo YHG=831>it YHG=831>would YHG=831>not YHG=831>have YHG=831>proved YHG=831>that YHG=830>it YHG=831>is YHG=831>exclusively : " XBD=136 XBD=240 XBD=474 XBD=725 XBD=804 XBD=888 XBD=1064 XHG=102 XHG=151 XHG=258 XHG=492 XHG=742 XHG=822 XHG=908 YBD=901 YBD=907 YBD=900 YBD=900 YHG=880>or YHG=879>even YHG=870>commonly YHG=870>responsible YHG=870>for YHG=869>the YHG=870>disease. " XBD=1435 XBD=1576 XBD=1669 XBD=1831 XBD=1902 XBD=1994 XBD=2190 XBD=2397 XBD=2523 XHG=1385 XHG=1460 XHG=1603 XHG=1694 XHG=1858 XHG=1927 XHG=2022 XHG=2216 XHG=2422 YBD=921 YBD=920 YBD=928 YBD=929 YBD=922 YHG=892>(1) YHG=891>From YHG=891>the YHG=890>lesions YHG=890>of YHG=890>130 YHG=890>patients YHG=891>suffering YHG=892>from " XBD=182 XBD=288 XBD=347 XBD=428 XBD=594 XBD=677 XBD=831 XBD=934 XBD=1132 XBD=1181 XBD=1272 XHG=140 XHG=196 XHG=304 XHG=358 XHG=444 XHG=611 XHG=694 XHG=846 XHG=949 XHG=1149 XHG=1198 YBD=945 YBD=947 YBD=939 YBD=947 YBD=940 YBD=939 YHG=910>In YHG=910>view YHG=909>of YHG=918>our YHG=909>results, YHG=909>the YHG=909>theory YHG=909>that YHG=909>impetigo YHG=909>is YHG=909>due " XBD=1515 XBD=1766 XBD=1856 XBD=2040 XBD=2155 XBD=2296 XBD=2401 XBD=2523 XHG=1331 XHG=1535 XHG=1786 XHG=1876 XHG=2057 XHG=2172 XHG=2349 XHG=2415 YBD=969 YBD=967 YBD=960 YBD=961 YBD=962 YHG=931>impetigo YHG=930>contagiosa, YHG=930>230 YHG=930>cultures YHG=939>were YHG=930>made. YHG=931>Of YHG=932>these " XBD=220 XBD=275 XBD=557 XBD=697 XBD=780 XBD=1052 XBD=1172 XBD=1272 XHG=99 XHG=235 XHG=309 XHG=593 XHG=732 XHG=815 XHG=1104 XHG=1207 YBD=985 YBD=986 YBD=979 YBD=978 YBD=979 YBD=979 YHG=949>solely, YHG=949>to YHG=949>streptococci YHG=950>must YHG=949>be YHG=948>abandoned. YHG=949>We YHG=958>are " XBD=2522 XHG=2327 YBD=1008 YHG=973>pyogenes) XBD=1418 XBD=1593 XBD=1899 XBD=2077 XBD=2152 XHG=1333 XHG=1442 XHG=1617 XHG=1925 XHG=2101 YBD=1007 YBD=1005 YBD=999 YHG=970>all YHG=970>97% YHG=970>yielded YHG=969>staphylococci YHG=970>(almost " XBD=264 XBD=333 XBD=408 XBD=585 XBD=688 XBD=787 XBD=902 XBD=1180 XBD=1271 XHG=99 XHG=291 XHG=361 XHG=435 XHG=613 XHG=717 XHG=815 XHG=929 XHG=1207 YBD=1025 YBD=1024 YBD=1017 YBD=1025 YBD=1018 YBD=1026 YBD=1018 YHG=987>prepared YHG=987>to YHG=996>go YHG=988>further YHG=988>and YHG=997>say YHG=988>that YHG=988>streptococci YHG=998>are " XBD=1408 XBD=1534 XBD=1871 XBD=2209 XBD=2333 XBD=2524 XHG=1331 XHG=1447 XHG=1680 XHG=1920 XHG=2236 XHG=2367 YBD=1040 YBD=1046 YBD=1039 YBD=1047 YHG=1010>and YHG=1009>32% YHG=1018>pyogenes. YHG=1009>Staphylococci YHG=1018>were YHG=1011>present " XBD=237 XBD=296 XBD=414 XBD=508 XBD=645 XBD=714 XBD=929 XBD=1014 XBD=1132 XBD=1273 XHG=98 XHG=261 XHG=315 XHG=441 XHG=534 XHG=670 XHG=734 XHG=979 XHG=1039 XHG=1156 YBD=1061 YBD=1062 YBD=1057 YBD=1056 YBD=1064 YBD=1057 YBD=1064 YBD=1057 YHG=1027>seldom, YHG=1025>if YHG=1035>ever, YHG=1027>the YHG=1036>cause YHG=1027>of YHG=1027>impetigo. YHG=1029>A YHG=1036>very YHG=1028>much " XBD=1495 XBD=1791 XBD=1851 XBD=1958 XBD=2018 XBD=2101 XBD=2301 XBD=2426 XBD=2522 XHG=1330 XHG=1611 XHG=1809 XHG=1873 XHG=1973 XHG=2035 XHG=2123 XHG=2315 XHG=2448 YBD=1086 YBD=1078 YBD=1084 YBD=1079 YHG=1049>without YHG=1057>pyogenes YHG=1049>in YHG=1047>67% YHG=1048>of YHG=1048>the YHG=1048>cultures, YHG=1048>while YHG=1049>Str. as " XBD=208 XBD=309 XBD=403 XBD=469 XBD=603 XBD=692 XBD=773 XBD=920 XBD=1121 XBD=1271 XHG=99 XHG=227 XHG=330 XHG=422 XHG=490 XHG=624 XHG=712 XHG=793 XHG=941 XHG=1204 YBD=1096 YBD=1095 YBD=1096 YBD=1103 YBD=1103 YBD=1097 YHG=1066>better YHG=1074>case YHG=1074>can YHG=1065>be YHG=1066>made YHG=1067>out YHG=1066>for YHG=1066>Staph. YHG=1075>pyogenes YHG=1067>the " XBD=1510 XBD=1608 XBD=1782 XBD=1967 XBD=2270 XBD=2325 XBD=2431 XBD=2520 XHG=1329 XHG=1530 XHG=1630 XHG=1803 XHG=1989 XHG=2284 XHG=2340 XHG=2445 YBD=1126 YBD=1118 YBD=1117 YBD=1125 YHG=1097>pyogenes YHG=1097>was YHG=1088>present YHG=1088>without YHG=1087>staphylococci YHG=1088>in YHG=1088>only YHG=1088>2%. " XBD=194 XBD=253 XBD=330 XBD=504 XBD=596 XBD=644 XBD=803 XBD=960 XBD=1130 XBD=1188 XBD=1271 XHG=99 XHG=211 XHG=266 XHG=348 XHG=557 XHG=613 XHG=662 XHG=819 XHG=977 XHG=1147 XHG=1204 YBD=1134 YBD=1134 YBD=1135 YBD=1136 YBD=1143 YBD=1143 YBD=1135 YBD=1136 YHG=1113>cause YHG=1104>of YHG=1104>the YHG=1104>disease. YHG=1105>It YHG=1106>is YHG=1106>almost YHG=1106>always YHG=1107>present YHG=1106>in YHG=1107>the " XBD=1505 XBD=1633 XBD=1707 XBD=1937 XBD=2120 XBD=2248 XBD=2322 XBD=2522 XHG=1333 XHG=1534 XHG=1664 XHG=1737 XHG=1964 XHG=2148 XHG=2279 XHG=2351 YBD=1158 YBD=1157 YBD=1156 YBD=1164 YHG=1128>Cultures YHG=1128>from YHG=1127>17 YHG=1127>unopened YHG=1127>vesicles YHG=1127>from YHG=1127>10 YHG=1128>patients " XBD=228 XBD=377 XBD=435 XBD=587 XBD=635 XBD=720 XBD=848 XBD=967 XBD=1160 XBD=1273 XHG=97 XHG=244 XHG=394 XHG=451 XHG=603 XHG=650 XHG=735 XHG=862 XHG=984 XHG=1176 YBD=1179 YBD=1173 YBD=1181 YBD=1174 YBD=1175 YBD=1176 YHG=1143>lesions, YHG=1143>failure YHG=1145>to YHG=1144>isolate YHG=1145>it YHG=1145>not YHG=1145>being YHG=1154>more YHG=1154>common YHG=1146>than " XBD=1482 XBD=1600 XBD=1971 XBD=2100 XBD=2257 XBD=2349 XBD=2522 XHG=1330 XHG=1510 XHG=1782 XHG=2023 XHG=2127 XHG=2283 XHG=2377 YBD=1204 YBD=1195 YBD=1203 YBD=1196 YBD=1197 YHG=1167>yielded YHG=1167>only YHG=1174>pyogenes. YHG=1166>The YHG=1166>longer YHG=1166>the YHG=1166>disease "" XBD=1269 XBD=214 XBD=279 XBD=438 XBD=506 XBD=748 XBD=813 XBD=941 XBD=1012 XHG=96 XHG=238 XHG=304 XHG=465 XHG=534 XHG=772 XHG=837 XHG=967 XHG=1041 YBD=1212 YBD=1212 YBD=1213 YBD=1221 YBD=1214 YBD=1214 YBD=1222 YHG=1182>failure YHG=1182>to YHG=1182>isolate YHG=1183>C. YHG=1183>diphtherice YHG=1185>in YHG=1193>cases YHG=1184>of YHG=1185>diphtheria. XBD=1408 XBD=1601 XBD=1696 XBD=1857 XBD=1960 XBD=2059 XBD=2317 XBD=2388 XHG=1330 XHG=1442 XHG=1631 XHG=1724 XHG=1883 XHG=1994 XHG=2092 XHG=2344 XHG=2419 YBD=1242 YBD=1235 YBD=1243 YBD=1234 YBD=1236 YHG=1206>had YHG=1205>existed, YHG=1206>the YHG=1205>higher YHG=1214>was YHG=1205>the YHG=1206>proportion YHG=1205>of YHG=1215>cases "" XBD=2522 XBD=184 XBD=424 XBD=487 XBD=554 XBD=605 XBD=690 XBD=855 XBD=919 XBD=1001 XBD=1211 XBD=1272 XHG=96 XHG=202 XHG=443 XHG=502 XHG=573 XHG=625 XHG=711 XHG=875 XHG=934 XHG=1022 XHG=1230 YBD=1251 YBD=1259 YBD=1252 YBD=1260 YBD=1253 YBD=1253 YBD=1261 YBD=1253 YHG=1221>Most YHG=1222>convincing YHG=1222>of YHG=1222>all YHG=1223>is YHG=1223>the YHG=1223>finding YHG=1224>of YHG=1224>the YHG=1224>organism YHG=1224>in XBD=1499 XBD=1793 XHG=1330 XHG=1603 YBD=1282 YHG=1245>yielding YHG=1253>pyogenes. " XBD=175 XBD=386 XBD=446 XBD=512 XBD=657 XBD=843 XHG=96 XHG=194 XHG=405 XHG=469 XHG=533 XHG=677 YBD=1298 YBD=1291 YBD=1290 YBD=1292 YBD=1293 YHG=1269>pure YHG=1260>condition YHG=1261>in YHG=1262>17 YHG=1262>intact YHG=1263>vesicles. " XBD=1433 XBD=1521 XBD=1747 XBD=1830 XBD=2036 XBD=2259 XHG=1382 XHG=1458 XHG=1561 XHG=1788 XHG=1871 XHG=2075 XHG=2302 YBD=1314 YBD=1313 YBD=1321 YBD=1320 YHG=1285>(2) YHG=1284>All YHG=1284>attempts YHG=1283>to YHG=1283>produce YHG=1283>impetigo YHG=1283>contagiosa "" XBD=2523 XBD=207 XBD=447 XBD=629 XBD=874 XBD=948 XBD=1093 XBD=1271 XHG=135 XHG=237 XHG=477 XHG=661 XHG=906 XHG=980 XHG=1122 YBD=1328 YBD=1336 YBD=1338 YBD=1331 YBD=1331 YBD=1339 YHG=1299>The YHG=1300>postulates YHG=1301>usually YHG=1301>attributed YHG=1302>to YHG=1301>Koch YHG=1301>require XBD=1646 XHG=1330 XHG=1661 YBD=1360 YBD=1353 YHG=1323>experimentally YHG=1322>failed. "" XBD=1789 XBD=185 XBD=292 XBD=370 XBD=691 XBD=745 XBD=820 XBD=1006 XBD=1061 XBD=1094 XBD=1270 XHG=95 XHG=198 XHG=306 XHG=387 XHG=701 XHG=755 XHG=829 XHG=1016 XHG=1071 XHG=1103 YBD=1369 YBD=1368 YBD=1369 YBD=1370 YBD=1378 YBD=1371 YBD=1378 YHG=1347>more YHG=1338>than YHG=1339>the YHG=1340>demonstration YHG=1341>of YHG=1341>the YHG=1349>presence YHG=1341>of YHG=1350>a YHG=1341>particuXBD=1433 XBD=1499 XBD=1547 XBD=1735 XBD=1839 XBD=2036 XBD=2274 XBD=2321 XBD=2475 XBD=2528 XHG=1382 XHG=1459 XHG=1515 XHG=1563 XHG=1751 XHG=1854 XHG=2053 XHG=2290 XHG=2338 XHG=2492 YBD=1392 YBD=1399 YBD=1398 YBD=1391 YHG=1362>(3) YHG=1362>It YHG=1362>is YHG=1362>believed YHG=1361>that YHG=1360>impetigo YHG=1361>contagiosa YHG=1361>is YHG=1361>rarely, YHG=1361>if " XBD=142 XBD=346 XBD=410 XBD=501 XBD=663 XBD=733 XBD=776 XBD=956 XBD=1061 XBD=1271 XHG=94 XHG=163 XHG=369 XHG=435 XHG=526 XHG=688 XHG=753 XHG=801 XHG=1008 XHG=1088 YBD=1408 YBD=1415 YBD=1408 YBD=1409 YBD=1410 YBD=1410 YHG=1379>lar YHG=1378>organism YHG=1378>in YHG=1379>the YHG=1379>lesions YHG=1380>of YHG=1389>a YHG=1380>disease. YHG=1380>To YHG=1380>establish " XBD=1432 XBD=1591 XBD=1666 XBD=1934 XBD=1999 XBD=2091 XBD=2216 XBD=2380 XBD=2437 XHG=1331 XHG=1452 XHG=1612 XHG=1685 XHG=1953 XHG=2014 XHG=2111 XHG=2265 XHG=2401 XHG=2452 YBD=1437 YBD=1431 YBD=1438 YBD=1435 YBD=1430 YHG=1410>ever, YHG=1401>caused YHG=1401>by YHG=1400>streptococci YHG=1401>of YHG=1409>any YHG=1401>type. YHG=1400>Most, YHG=1400>if YHG=1402>not "" XBD=2522 XBD=136 XBD=364 XBD=457 XBD=566 XBD=728 XBD=793 XBD=1038 XBD=1111 XBD=1271 XHG=94 XHG=149 XHG=378 XHG=472 XHG=580 XHG=743 XHG=809 XHG=1050 XHG=1125 YBD=1448 YBD=1454 YBD=1447 YBD=1456 YBD=1457 YBD=1449 YBD=1449 YBD=1449 YHG=1418>its YHG=1416>aetiological YHG=1418>r6le YHG=1418>they YHG=1419>require YHG=1419>its YHG=1419>cultivation YHG=1419>for YHG=1419>several XBD=1395 XBD=1513 XBD=1590 XBD=1677 XBD=1733 XBD=2066 XBD=2209 XBD=2342 XBD=2466 XBD=2522 XHG=1329 XHG=1409 XHG=1526 XHG=1603 XHG=1690 XHG=1888 XHG=2079 XHG=2221 XHG=2356 XHG=2480 YBD=1476 YBD=1471 YBD=1478 YBD=1477 YBD=1470 YBD=1469 YHG=1441>all, YHG=1450>cases YHG=1450>are YHG=1440>due YHG=1441>to YHG=1449>pyogenes YHG=1440>acting YHG=1440>either YHG=1439>alone YHG=1449>or " XBD=313 XBD=478 XBD=560 XBD=690 XBD=975 XBD=1034 XBD=1111 XBD=1269 XHG=95 XHG=329 XHG=494 XHG=575 XHG=709 XHG=990 XHG=1044 XHG=1125 YBD=1495 YBD=1488 YBD=1490 YBD=1496 YBD=1488 YBD=1489 YHG=1457>generations YHG=1458>outside YHG=1458>the YHG=1459>body, YHG=1459>reproduction YHG=1459>of YHG=1459>the YHG=1459>disease " XBD=1371 XBD=1640 XBD=1757 XBD=1801 XBD=2085 XBD=2244 XBD=2334 XBD=2521 XHG=1329 XHG=1394 XHG=1661 XHG=1778 XHG=1823 XHG=2106 XHG=2268 XHG=2357 YBD=1510 YBD=1517 YBD=1514 YBD=1509 YBD=1516 YHG=1481>in YHG=1480>conjunction YHG=1481>with YHG=1488>a YHG=1480>hypothetical YHG=1480>factor, YHG=1479>the YHG=1479>possible " XBD=189 XBD=243 XBD=298 XBD=549 XBD=656 XBD=749 XBD=879 XBD=947 XBD=1020 XBD=1186 XBD=1271 XHG=95 XHG=211 XHG=265 XHG=323 XHG=574 XHG=683 XHG=774 XHG=904 XHG=968 XHG=1044 XHG=1214 YBD=1526 YBD=1526 YBD=1528 YBD=1535 YBD=1527 YBD=1527 YBD=1528 YBD=1534 YHG=1496>when YHG=1496>it YHG=1497>is YHG=1496>introduced YHG=1498>into YHG=1498>the YHG=1498>body YHG=1498>of YHG=1507>an YHG=1498>animal " XBD=1933 XBD=1467 XHG=1729 XBD=1530 XBD=1664 XBD=1712 XHG=1331 YBD=1550 XHG=1485 XHG=1541 XHG=1679 YBD=1549 YHG=1499>(or YBD=1551 YHG=1520>nature YHG=1520>of YHG=1519>which YHG=1519>is YHG=1518>discussed. " XBD=197 XBD=299 XBD=376 XBD=583 XBD=710 XBD=802 XBD=965 XBD=1035 XBD=1268 XHG=94 XHG=224 XHG=325 XHG=403 XHG=610 XHG=736 XHG=829 XHG=993 XHG=1062 YBD=1571 YBD=1565 YBD=1566 YBD=1567 YBD=1567 YBD=1574 YHG=1536>man), YHG=1535>and YHG=1536>its YHG=1536>isolation YHG=1537>from YHG=1537>the YHG=1536>lesions YHG=1546>so YHG=1537>produced. " XBD=1434 XBD=1540 XBD=1670 XBD=1873 XBD=1939 XBD=2060 XBD=2156 XBD=2226 XBD=2363 XBD=2522 XHG=1383 XHG=1459 XHG=1562 XHG=1690 XHG=1895 XHG=1958 XHG=2084 XHG=2178 XHG=2249 XHG=2385 YBD=1595 YBD=1596 YBD=1588 YBD=1587 YHG=1559>(4) YHG=1559>The YHG=1559>great YHG=1558>majority YHG=1557>of YHG=1567>cases YHG=1566>can YHG=1557>be YHG=1557>cured YHG=1557>within " XBD=151 XBD=262 XBD=570 XBD=655 XBD=815 XBD=1013 XBD=1209 XBD=1274 XHG=93 XHG=168 XHG=282 XHG=589 XHG=674 XHG=834 XHG=1032 XHG=1229 YBD=1605 YBD=1604 YBD=1605 YBD=1606 YBD=1606 YBD=1613 YBD=1605 YHG=1575>We YHG=1575>have YHG=1575>demonstrated YHG=1577>the YHG=1576>almost YHG=1576>constant YHG=1585>presence YHG=1576>of " XBD=1376 XBD=1491 XBD=1562 XBD=1674 XBD=1910 XBD=2039 XBD=2254 XBD=2334 XBD=2522 XHG=1332 XHG=1396 XHG=1508 XHG=1576 XHG=1690 XHG=1960 XHG=2057 XHG=2270 XHG=2351 YBD=1635 YBD=1634 YBD=1628 YBD=1627 YBD=1626 YHG=1598>10 YHG=1597>days YHG=1598>by YHG=1598>local YHG=1597>treatment. YHG=1597>The YHG=1596>essentials YHG=1606>are YHG=1596>removal Staph. " XBD=402 XBD=461 XBD=664 XBD=821 XBD=917 XBD=1036 XBD=1269 XHG=224 XHG=421 XHG=480 XHG=684 XHG=841 XHG=937 XHG=1057 YBD=1651 YBD=1652 YBD=1645 YBD=1645 YBD=1645 YHG=1622>pyogenes YHG=1615>in YHG=1615>impetigo YHG=1615>lesions YHG=1615>and YHG=1615>have YHG=1615>cultivated " XBD=1374 XBD=1524 XBD=1770 XBD=1832 XBD=2072 XBD=2275 XBD=2370 XBD=2520 XHG=1329 XHG=1389 XHG=1544 XHG=1787 XHG=1847 XHG=2090 XHG=2292 XHG=2389 YBD=1672 YBD=1674 YBD=1667 YBD=1665 YBD=1666 YHG=1637>crusts, YHG=1637>prevention YHG=1637>of YHG=1636>extraneous YHG=1635>infection YHG=1636>and YHG=1635>avoid" XBD=149 XBD=351 XBD=522 XBD=609 XBD=745 XBD=838 XBD=914 XBD=1032 XBD=1123 XBD=1267 XHG=93 XHG=168 XHG=371 XHG=543 XHG=629 XHG=767 XHG=857 XHG=933 XHG=1053 XHG=1141 YBD=1683 YBD=1691 YBD=1692 YBD=1684 YBD=1684 YBD=1683 YBD=1692 YHG=1653>the YHG=1653>organism YHG=1654>outside YHG=1654>the YHG=1654>body, YHG=1655>but YHG=1663>we YHG=1654>have YHG=1654>not YHG=1663>repro" XBD=1422 XBD=1494 XBD=1707 XBD=1973 XBD=2340 XBD=2520 XHG=1328 XHG=1450 XHG=1515 XHG=1732 XHG=2024 XHG=2367 YBD=1706 YBD=1713 YBD=1705 YBD=1712 YHG=1685>ance YHG=1676>of YHG=1671>irritating YHG=1676>medication. YHG=1675>Sulphonamides YHG=1674>applied " XBD=200 XBD=283 XBD=446 XBD=520 XBD=616 XBD=680 XBD=760 XBD=955 XBD=1020 XBD=1269 XHG=61 XHG=218 XHG=303 XHG=466 XHG=539 XHG=636 XHG=694 XHG=780 XHG=975 XHG=1034 YBD=1729 YBD=1722 YBD=1730 YBD=1723 YBD=1723 YBD=1723 YHG=1692>duced YHG=1692>the YHG=1693>disease YHG=1693>by YHG=1703>any YHG=1694>of YHG=1694>the YHG=1693>methods YHG=1693>of YHG=1693>inoculation " XBD=1466 XBD=1567 XBD=1623 XBD=1797 XBD=1854 XBD=1953 XBD=2177 XBD=2384 XHG=1327 XHG=1479 XHG=1581 XHG=1637 XHG=1810 XHG=1868 XHG=1967 XHG=2188 YBD=1745 YBD=1752 YBD=1744 YHG=1715>locally YHG=1715>help YHG=1715>to YHG=1715>prevent YHG=1724>or YHG=1723>cure YHG=1714>secondary YHG=1714>infection. " XBD=959 XBD=131 XHG=756 XBD=202 XBD=407 XBD=549 XBD=623 XBD=739 XHG=93 YBD=1761 XHG=142 XHG=219 XHG=425 XHG=567 XHG=640 YBD=1761YHG=1731>of YBD=1768 YBD=1762 YBD=1763 YBD=1770 YHG=1731>the YHG=1733>organism YHG=1733>which YHG=1741>we YHG=1733>have YHG=1732>practised. " XBD=1268 XBD=180 XHG=854 XBD=285 XBD=412 XBD=515 XBD=677 XBD=827 XBD=997 XBD=1064 XBD=1171 XHG=132 XHG=203 XHG=309 XHG=438 XHG=542 XHG=702 XHG=1023 XHG=1091 XHG=1197 YBD=1800 YBD=1809 YBD=1801 YBD=1808 YBD=1800 YBD=1801 YHG=1771>At YHG=1770>first YHG=1772>sight YHG=1771>this YHG=1771>failure YHG=1771>would YHG=1780>appear YHG=1771>to YHG=1771>rule YHG=1771>out " XBD=1266 XBD=205 XHG=761 XBD=403 XBD=466 XBD=554 XBD=685 XBD=748 XBD=969 XBD=1072 XBD=1147 XHG=92 XHG=225 XHG=423 XHG=487 XHG=574 XHG=705 XHG=1000 XHG=1090 XHG=1167 YBD=1848 YBD=1841 YBD=1840 YBD=1847 YBD=1840 YBD=1839 YHG=1810>Staph. YHG=1819>pyogenes YHG=1820>as YHG=1811>the YHG=1819>cause YHG=1810>of YHG=1810>impetigo YHG=1810>but YHG=1819>we YHG=1810>have ; " XBD=1272 XBD=228 XHG=808 XBD=355 XBD=413 XBD=596 XBD=793 XBD=862 XBD=1020 XBD=1210 XHG=92 XHG=240 XHG=371 XHG=428 XHG=610 XHG=876 XHG=1033 XHG=1226 YBD=1887 YBD=1879 YBD=1887 YBD=1886 YBD=1879 YBD=1879 YHG=1849>equally YHG=1849>failed YHG=1850>to YHG=1850>produce YHG=1849>impetigo YHG=1849>by YHG=1849>similar YHG=1849>methods YHG=1849>of " XBD=1267 XBD=307 XHG=944 XBD=446 XBD=641 XBD=770 XBD=909 XBD=987 XBD=1085 XHG=89 XHG=334 XHG=476 XHG=669 XHG=805 XHG=1020 XHG=1122 YBD=1919 YBD=1926 YBD=1919 YBD=1918 YBD=1917 YBD=1918 YHG=1888>inoculation YHG=1889>using YHG=1888>exudate YHG=1888>from YHG=1897>cases YHG=1888>of YHG=1888>the YHG=1888>disease " XBD=1265 XBD=199 XHG=640 XBD=352 XBD=532 XBD=618 XBD=835 XBD=1046 XBD=1111 XHG=91 XHG=219 XHG=375 XHG=552 XHG=856 XHG=1068 XHG=1131 YBD=1958 YBD=1958 YBD=1957 YBD=1964 YBD=1956 YBD=1964 YHG=1928>which YHG=1927>should YHG=1928>contain YHG=1928>the YHG=1927>causative YHG=1926>organism YHG=1936>or YHG=1936>organ" XBD=1265 XBD=179 XHG=905 XBD=304 XBD=575 XBD=640 XBD=728 XBD=883 XBD=947 XBD=1176 XHG=90 XHG=227 XHG=327 XHG=596 XHG=658 XHG=747 XHG=969 XHG=1198 YBD=1997 YBD=2004 YBD=1996 YBD=2003 YBD=1996 YHG=1967>isms. YHG=1967>The YHG=1967>explanation YHG=1966>of YHG=1975>our YHG=1966>failure YHG=1967>to YHG=1966>reproduce YHG=1967>the " XBD=1265 XBD=218 XHG=819 XBD=286 XBD=534 XBD=639 XBD=701 XBD=804 XBD=887 XBD=1154 XHG=91 XHG=232 XHG=299 XHG=548 XHG=652 XHG=716 XHG=900 XHG=1168 YBD=2037 YBD=2036 YBD=2043 YBD=2035 YBD=2034 YBD=2035 YBD=2035 YHG=2007>disease YHG=2004>by YHG=2005>inoculation YHG=2014>may YHG=2005>be YHG=2006>that YHG=2014>our YHG=2005>inoculations YHG=2014>were " XBD=1265 XBD=286 XHG=749 XBD=449 XBD=518 XBD=600 XBD=732 XBD=915 XBD=1116 XHG=89 XHG=303 XHG=466 XHG=534 XHG=618 XHG=932YBD=2083 XHG=1134 YBD=2082 YBD=2075 YBD=2079 YBD=2074 YBD=2081 YBD=2074 YHG=2045>performed YHG=2045>mainly YHG=2054>on YHG=2045>the YHG=2054>arms, YHG=2044>whereas YHG=2043>impetigo YHG=2053>occurs XBD=190 XHG=904 XBD=317 XBD=563 XBD=639 XBD=732 XBD=852 XBD=944 XBD=1107 XBD=1181 XBD=1264 XHG=89 XHG=214 XHG=344 XHG=589 XHG=666 XHG=757 XHG=969 XHG=1133 XHG=1208 YBD=2115 YBD=2114 YBD=2121 YBD=2113 YBD=2113 YBD=2113 YHG=2085>much YHG=2093>more YHG=2084>commonly YHG=2093>on YHG=2084>the YHG=2084>face. YHG=2084>It YHG=2083>should YHG=2083>be YHG=2092>re" XBD=2525 XBD=1492 XBD=1580 XBD=1864 XBD=1924 XBD=2010 XBD=2320 XBD=2461 XHG=1371 XHG=1512 XHG=1601 XHG=1884 XHG=1943 XHG=2032 XHG=2341 XHG=2486 YBD=2122 YBD=2129 YBD=2121 YHG=2091>SiNCB YHG=2090>the YHG=2090>introduction YHG=2091>of YHG=2091>the YHG=2090>sulphonamide YHG=2101>group YHG=2090>of " XBD=224 XBD=424 XBD=478 XBD=567 XBD=791 XBD=889 XBD=941 XBD=1058 XHG=90 XHG=239 XHG=437 XHG=489 XHG=579 XHG=802 XHG=954 XHG=1072 YBD=2159 YBD=2159 YBD=2153 YBD=2152 YBD=2152 YBD=2153 YHG=2124>corded, YHG=2124>however, YHG=2124>in YHG=2123>this YHG=2122>connexion YHG=2123>that YHG=2123>in YHG=2132>some YHG=2123>instances " XBD=1265 XBD=1437XHG=900 XBD=1574 XBD=1703 XBD=1831 XBD=2004 XBD=2325 XBD=2395 XBD=2526 XHG=1323 XHG=1465 XHG=1604 XHG=1735 XHG=1860 XHG=2033 XHG=2355 XHG=2424 YBD=2161 YBD=2168 YBD=2160 YHG=2131>drugs YHG=2130>there YHG=2131>have YHG=2131>been YHG=2130>several YHG=2129>investigations YHG=2131>of YHG=2131>their " XBD=305 XBD=366 XBD=445 XBD=548 XBD=609 XBD=673 XBD=818 XBD=921 XBD=1053 XBD=1113 XBD=1154 XHG=89 XHG=323 XHG=379 XHG=462 XHG=565 XHG=621 XHG=689 XHG=936 XHG=1070 XHG=1129 XHG=1171 YBD=2193 YBD=2193 YBD=2191 YBD=2192 YBD=2192 YBD=2192 YHG=2162>inoculation YHG=2163>of YHG=2163>the YHG=2163>face YHG=2162>of YHG=2171>an YHG=2162>actual YHG=2171>case YHG=2162>failed YHG=2163>at YHG=2171>a YHG=2163>time " XBD=1265 XBD=1434XHG=835 XBD=1506 XBD=1601 XBD=1841 XBD=1910 XBD=2123 XBD=2386 XBD=2526 XHG=1321 XHG=1462 XHG=1534 XHG=1631 XHG=1871 XHG=1938 XHG=2153 XHG=2419 YBD=2207 YBD=2200 YHG=2170>value YHG=2170>in YHG=2170>the YHG=2169>treatment YHG=2170>of YHG=2170>impetigo YHG=2169>contagiosa, YHG=2170>often XBD=185 XHG=748 XBD=284 XBD=439 XBD=667 XBD=729 XBD=891 XBD=1108 XBD=1179 XBD=1265 XHG=89 XHG=202 XHG=301 XHG=460 XHG=686 XHG=910 XHG=1128 XHG=1198 YBD=2232 YBD=2232 YBD=2231 YBD=2238 YBD=2231 YBD=2231 YBD=2232 YHG=2204>when YHG=2211>new YHG=2202>lesions YHG=2201>continued YHG=2202>to YHG=2210>appear YHG=2201>elsewhere YHG=2210>on YHG=2201>the XBD=1440 XBD=1522 XBD=1617 XBD=1744 XBD=1862 XBD=1956 XHG=1321 XHG=1470 XHG=1549 XHG=1647 XHG=1771 XHG=1889 YBD=2240 YBD=2239 YHG=2208>based YHG=2218>on YHG=2208>the YHG=2209>view YHG=2209>that " XBD=2525 XBD=2357 XBD=2428 XHG=2240 XHG=2388 XHG=2456 YBD=2246 YBD=2238 YHG=2209>agent YHG=2208>of YHG=2209>the " XBD=160 XBD=233 XBD=327 XBD=465 XBD=647 XBD=768 XBD=872 XBD=977 XBD=1162 XBD=1266 XHG=89 XHG=191 XHG=261 XHG=360 XHG=498 XHG=697 XHG=801 XHG=904 XHG=1010 XHG=1195 YBD=2271 YBD=2270 YBD=2277 YBD=2269 YBD=2277 YBD=2270 YHG=2241>face YHG=2241>of YHG=2241>the YHG=2249>same YHG=2249>person. YHG=2240>We YHG=2249>can YHG=2240>but YHG=2249>express YHG=2248>our |>" XBD=1467 XBD=1520 XBD=1563 XBD=2109 XBD=2188 XBD=2473 XBD=2525 XBD=1798 XHG=1322 XHG=1485 XHG=1540 XHG=1816 XHG=2152 XHG=2207 XHG=2491 XHG=1583 YBD=2278 YBD=2285 YBD=2284 YHG=2248>disease YHG=2257>a YHG=2248>streptococcus. YHG=2248>A YHG=2247>bibliography YHG=2248>is YHG=2248>haemolytic XBD=236 XHG=872 XBD=301 XBD=395 XBD=552 XBD=618 XBD=847 XBD=896 XBD=1063 XBD=1210 XBD=1265 XHG=90 XHG=259 XHG=325 XHG=416 XHG=576 XHG=642 XHG=919 XHG=1086 XHG=1232 YBD=2317 YBD=2309 YBD=2316 YBD=2308 YBD=2309 YBD=2309 YHG=2280>surprise YHG=2280>at YHG=2288>our YHG=2279>failure YHG=2279>to YHG=2278>reproduce YHG=2288>a YHG=2278>disease YHG=2280>which YHG=2280>is " XBD=2524 XBD=1437 XBD=1504 XBD=1648 XBD=1799 XBD=1927 XBD=2095 XBD=2227 XBD=2274 XBD=2340 XHG=1321 XHG=1450 XHG=1520 XHG=1666 XHG=1849 XHG=1942 XHG=2109 XHG=2239 XHG=2288 XHG=2354 YBD=2324 YBD=2317 YBD=2325 YHG=2287>given YHG=2287>by YHG=2286>Cohen YHG=2286>(1942). YHG=2287>The YHG=2286>present YHG=2286>study YHG=2286>is YHG=2296>an YHG=2286>attempt

SUMMARY

Staph. Str. Str.

Staph. Str.

Staph.

IMPETIGO ÆTIOLOGY AND TREATMENT H. L. SHEEHAN MD, D SC MANC, M R C P LIEUT.-COLONEL RAMC

A. GIRDWOOD FERGUSSON M D GLASG,

F R F PS

MAJOR RAMC

eetiological

XBD=216 XHG=461 XBD=319 XBD=377 XBD=443 XBD=696 XHG=90 XHG=231 XHG=336 XHG=395 YBD=2355 YBD=2348 YBD=2347 YBD=2355 YHG=2320>always YHG=2319>held YHG=2319>to YHG=2318>be YHG=2318>contagious. " XBD=2337 XBD=1364 XBD=1521 XBD=1642 XBD=1808 XBD=2005 XBD=2077 XBD=2161 XHG=1321 XHG=1386 XHG=1540 XHG=1661 XHG=1827 XHG=2027 XHG=2095 XHG=2182 YBD=2355 YBD=2356 YHG=2326>to YHG=2326>obtain YHG=2335>some YHG=2326>further YHG=2325>evidence YHG=2335>on YHG=2325>the YHG=2325>matter.

" " " " " " " " " " " " " " " " " " " " " " " " "

XBD=1266 XBD=166 XBD=205 XBD=378 XBD=479 XBD=674 XBD=718 XBD=869 XBD=934 XBD=1074 XHG=130 XHG=175 XHG=217 XHG=391 XHG=490 XHG=686 XHG=731 XHG=946 XHG=1086 YBD=2388 YBD=2395 YBD=2387 YBD=2394 YBD=2395 YBD=2395 YHG=2359>It YHG=2358>is YHG=2357>possible YHG=2358>that YHG=2357>impetigo YHG=2357>is YHG=2357>caused YHG=2356>by YHG=2356>Staph. YHG=2366>pyogenes XBD=1449XHG=881 XBD=1640 XBD=1911 XBD=2024 XBD=2091 XBD=2266 XBD=2380 XBD=2525 XHG=1372 XHG=1469 XHG=1656 XHG=1928 XHG=2047 XHG=2111 XHG=2283 XHG=2397 YBD=2402 YBD=2394 YHG=2365>The YHG=2365>patients YHG=2364>investigated YHG=2374>were YHG=2365>97 YHG=2365>soldiers YHG=2365>with YHG=2365>active XBD=296 XHG=714 XBD=375 XBD=505 XBD=688 XBD=758 XBD=1013 XBD=1266 XHG=89 XHG=322 XHG=400 XHG=529 XHG=778 XHG=1037 YBD=2427 YBD=2433 YBD=2426 YBD=2425 YBD=2426 YHG=2397>introduced YHG=2396>by YHG=2405>some YHG=2396>method YHG=2396>of YHG=2396>inoculation YHG=2396>completely XBD=1594 XBD=1759 XBD=1824 XBD=1901 XBD=2232 XBD=2374 XBD=2526 XHG=1320 XHG=1619 XHG=1781 XHG=1850 XHG=1927 XHG=2256 XHG=2424 YBD=2433 YBD=2441 YBD=2434 YHG=2403>impetiginous YHG=2403>resions YHG=2403>in YHG=2413>an YHG=2403>uncomplicated YHG=2403>state. YHG=2404>Most XBD=250 XHG=750 XBD=364 XBD=492 XBD=565 XBD=676 XBD=733 XBD=819 XBD=1023 XBD=1082 XBD=1265 XHG=90 XHG=265 XHG=381 XHG=509 XHG=582 XHG=692 XHG=836 XHG=1039 XHG=1099 YBD=2465 YBD=2464 YBD=2465 YBD=2472 YBD=2465 YHG=2436>different YHG=2435>from YHG=2435>those YHG=2444>we YHG=2434>used YHG=2434>in YHG=2444>our YHG=2435>attempts YHG=2436>to YHG=2435>produce XBD=1401 XBD=1502 XBD=1575 XBD=1772 XBD=2014 XBD=2184 XBD=2229 XBD=2323 XBD=2425 XBD=2526 XHG=1322 XHG=1423 XHG=1523 XHG=1596 XHG=1791 XHG=2034 XHG=2204 XHG=2250 XHG=2345 XHG=2446 YBD=2479 YBD=2478 YBD=2480 YBD=2472 YBD=2473 YHG=2452>no YHG=2442>previous YHG=2442>treatment, YHG=2442>though YHG=2452>a YHG=2443>few YHG=2443>had YHG=2442>had XBD=145 XBD=314 XHG=90 YBD=2504 YBD=2504 YHG=2474>the YHG=2475>disease’ experimentally. XBD=1426XHG=163 XBD=1651 XBD=1787 XBD=1879 XBD=2094 XBD=2206 XBD=2383 XBD=2524 XHG=1322 XHG=1439 XHG=1664 XHG=1801 XHG=1894 XHG=2109 XHG=2218 XHG=2399 YBD=2510 YBD=2518 YBD=2511 YBD=2512 YHG=2490>some YHG=2480>treatment YHG=2480>which YHG=2480>had YHG=2480>obviously YHG=2481>been YHG=2481>without YHG=2481>effect. XBD=201 XHG=883 XBD=438 XBD=579 XBD=749 XBD=807 XBD=866 XBD=915 XBD=1020 XBD=1217 XBD=1266 XHG=129 XHG=217 XHG=453 XHG=593 XHG=765 XHG=822 XHG=931YBD=2542 XHG=1034 XHG=1233 YBD=2550 YBD=2549 YBD=2542 YBD=2542 YHG=2513>The YHG=2513>hypothesis YHG=2512>which YHG=2512>appeals YHG=2513>to YHG=2521>us YHG=2512>is YHG=2512>that YHG=2512>impetigo YHG=2512>is XBD=1431 XBD=1544 XBD=1612 XBD=1856 XBD=1999 XBD=2059 XBD=2175 XBD=2368 XBD=2526 XHG=1324 XHG=1446 XHG=1561 XHG=1628 XHG=1873 XHG=2016 XHG=2076 XHG=2192 XHG=2383 YBD=2557 YBD=2556 YBD=2549 YBD=2558 YBD=2550 YHG=2520>They YHG=2528>were YHG=2520>all YHG=2519>sufficiently YHG=2528>severe YHG=2519>to YHG=2521>have YHG=2520>required YHG=2520>admisXBD=1113 XBD=1215 XBD=1266 XHG=934 XHG=1138 XHG=1240 YBD=2589 YBD=2581 YHG=2559>pyogenes YHG=2551>and YHG=2560>x Staph. XBD=152 XHG=714 XBD=215 XBD=306 XBD=533 XBD=689 XBD=758 XHG=89 XHG=176 XHG=240 XHG=332 XHG=560 YBD=2582 YBD=2582 YBD=2581 YHG=2551>due YHG=2552>to YHG=2552>the YHG=2551>combined YHG=2551>action YHG=2551>of XBD=1407 XBD=1466 XBD=1664 XBD=1782 XBD=1904 XBD=2076 XBD=2186 XBD=2245 XBD=2313 XBD=2396 XBD=2525 XHG=1321 XHG=1422 XHG=1483 XHG=1704 XHG=1801 XHG=1921 XHG=2091 XHG=2205 XHG=2260 XHG=2328 XHG=2413 YBD=2595 YBD=2588 YBD=2589 YBD=2590 YHG=2558>sion YHG=2558>to YHG=2558>hospital. YHG=2558>The YHG=2567>cases YHG=2558>studied YHG=2568>were YHG=2559>of YHG=2559>all YHG=2559>the YHG=2559>usual XBD=196 XBD=244 XBD=300 XBD=376 XBD=595 XBD=754 XBD=950 XBD=1018 XBD=1265 XHG=88 XHG=221 XHG=268 XHG=325 XHG=401 XHG=619 XHG=975 XHG=1042 YBD=2620 YBD=2625 YBD=2620 YBD=2620 YBD=2626 YHG=2591>where YHG=2600>x YHG=2591>is YHG=2600>an YHG=2590>unknown YHG=2590>factor, YHG=2590>animate YHG=2599>or YHG=2590>inanimate, XBD=1472XHG=782 XBD=1611 XBD=1702 XBD=1894 XBD=1933 XBD=2055 XBD=2112 XBD=2309 XBD=2522 XHG=1322 XHG=1486 XHG=1625 XHG=1716 XHG=1912 XHG=1951 XHG=2072 XHG=2128 XHG=2326 YBD=2635 YBD=2628 YBD=2627 YBD=2636 YHG=2597>clinical YHG=2597>types, YHG=2597>and YHG=2597>included YHG=2599>7 YHG=2606>cases YHG=2597>of YHG=2597>circinate YHG=2598>impetigo. XBD=243 XBD=328 XBD=565 XBD=694 XBD=873 XBD=960 XBD=1064 XBD=1264 XHG=88 XHG=285 XHG=370 XHG=616 XHG=737 XHG=997 XHG=1107 YBD=2666 YBD=2662 YBD=2659 YBD=2659 YBD=2665 YHG=2630>physical YHG=2639>or YHG=2629>chemical. YHG=2630>The YHG=2630>nature YHG=2629>of YHG=2630>the YHG=2629>disease, XBD=1643XHG=916 XBD=1746 XBD=2005 XBD=2125 XBD=2306 XBD=2373 XBD=2424 XBD=2524 XHG=1324 XHG=1668 XHG=1772 XHG=2030 XHG=2152 XHG=2332 XHG=2400 XHG=2452 YBD=2666 YBD=2674 YBD=2667 YBD=2668 YHG=2636>Lymphadenitis YHG=2637>and YHG=2636>paronychia YHG=2645>were YHG=2637>present YHG=2638>in YHG=2647>a YHG=2637>few XBD=273 XHG=887 XBD=331 XBD=399 XBD=523 XBD=678 XBD=869 XBD=975 XBD=1017 XBD=1158 XBD=1222 XBD=1266 XHG=89 XHG=290 XHG=348 XHG=418 XHG=540 XHG=698 XHG=992 XHG=1034 XHG=1175 XHG=1241 YBD=2705 YBD=2697 YBD=2706 YBD=2705 YBD=2704 YBD=2698 YBD=2697 YBD=2697 YBD=2698 YHG=2668>especially YHG=2669>in YHG=2668>its YHG=2669>early YHG=2669>stages, YHG=2669>suggests YHG=2668>that YHG=2676>x YHG=2668>might YHG=2668>be YHG=2677>a XBD=1525 XBD=1654 XBD=1981 XBD=2169 XBD=2243 XBD=2347 XBD=2450 XBD=2526 XHG=1319 XHG=1575 XHG=1679 XHG=2004 XHG=2192 XHG=2265 XHG=2371 XHG=2475 YBD=2704 YBD=2712 YBD=2705 YBD=2706 YBD=2709 YHG=2675>instances. YHG=2675>The YHG=2675>bacteriological YHG=2675>findings YHG=2676>film YHG=2677>and YHG=2685>on XBD=191 XBD=284 XBD=367 XBD=493 XBD=652 XBD=809 XBD=900 XBD=966 XBD=1125 XBD=1263 XHG=89 XHG=208 XHG=301 XHG=389 XHG=515 XHG=672 XHG=829 XHG=987 XHG=1146 YBD=2741 YBD=2744 YBD=2737 YBD=2736 YBD=2744 YBD=2736 YHG=2707>virus, YHG=2707>and YHG=2708>the YHG=2707>virus YHG=2708>theory YHG=2707>should YHG=2707>not YHG=2707>be YHG=2707>lightly YHG=2707>abanXBD=1467XHG=919 XBD=1588 XBD=1656 XBD=1745 XBD=1877 XBD=2043 XBD=2110 XBD=2244 XBD=2447 XBD=2525 XHG=1322 XHG=1493 XHG=1613 XHG=1677 XHG=1770 XHG=1897 XHG=2066 XHG=2133 XHG=2267 XHG=2471 YBD=2742 YBD=2743 YBD=2744 YBD=2752 YHG=2713>culture YHG=2722>were YHG=2713>in YHG=2713>the YHG=2713>main YHG=2714>similar YHG=2714>to YHG=2715>those YHG=2715>reported YHG=2714>by XBD=219 XHG=829 XBD=312 XBD=355 XBD=396 XBD=503 XBD=599 XBD=682 XBD=818 XBD=964 XBD=1039 XBD=1151 XBD=1202 XBD=1263 XHG=89 XHG=240 XHG=322 XHG=362 XHG=407 XHG=514 XHG=611 XHG=692 XHG=973 XHG=1048 XHG=1161 XHG=1214 YBD=2780 YBD=2776 YBD=2775 YBD=2782 YBD=2776 YBD=2775 YHG=2744>doned YHG=2746>but YHG=2746>if YHG=2746>it YHG=2755>were YHG=2747>true YHG=2755>one YHG=2745>would YHG=2746>expect YHG=2746>the YHG=2745>virus YHG=2746>to YHG=2745>be ; XBD=1424 XBD=1623 XBD=1927 XBD=2030 XBD=2143 XBD=2233 XBD=2362 XBD=2526 XHG=1321 XHG=1446 XHG=1646 XHG=1951 XHG=2053 XHG=2166 XHG=2258 XHG=2386 YBD=2789 YBD=2782 YBD=2791 YBD=2783 YHG=2753>most YHG=2752>previous YHG=2751>investigators, YHG=2753>and YHG=2753>only YHG=2753>the YHG=2763>more YHG=2754>salient XBD=226 XBD=281 XBD=361 XBD=515 XBD=629 XBD=745 XBD=832 XBD=1164 XBD=1263 XHG=89 XHG=240 XHG=295 XHG=379 XHG=536 XHG=651 XHG=852 XHG=1185 YBD=2819 YBD=2813 YBD=2814 YBD=2821 YBD=2814 YHG=2785>present YHG=2784>in YHG=2785>the YHG=2785>vesicle YHG=2784>fluid YHG=2785>with YHG=2784>the YHG=2784>staphylococcus YHG=2784>and XBD=1450XHG=766 XBD=1566 XBD=1631 XBD=1780 XHG=1318 XHG=1469 XHG=1585 XHG=1651 YBD=2829 YBD=2821 YBD=2820 YHG=2791>points YHG=2791>need YHG=2790>be YHG=2790>noted. XBD=165 XBD=243 XBD=494 XBD=555 XBD=633 XBD=726 XBD=868 XBD=1049 XBD=1261 XHG=89 XHG=180 XHG=259 XHG=511 XHG=567 XHG=650 XHG=884 XHG=1065 YBD=2852 YBD=2853 YBD=2860 YBD=2861 YHG=2821>that YHG=2823>inoculation YHG=2823>of YHG=2823>the YHG=2824>two YHG=2823>would YHG=2823>produce YHG=2823>impetigo. XBD=1666XHG=743 XBD=1823 XBD=1924 XBD=2091 XBD=2525 XHG=1368 XHG=1689 XHG=1845 XHG=1948 XHG=2115 YBD=2859 YBD=2860 YBD=2867 YBD=2868 YHG=2830>Staphylococcus YHG=2838>aureus YHG=2839>was YHG=2830>always YHG=2830>coagulase-positive XBD=147 XBD=277 XBD=328 XBD=493 XBD=593 XBD=628 XBD=670 XBD=890 XBD=978 XBD=1020 XBD=1262 XHG=89 XHG=158 XHG=287 XHG=340 XHG=505 XHG=604 XHG=638 XHG=680 XHG=988 XHG=1033 YBD=2890 YBD=2898 YBD=2891 YBD=2900 YBD=2893 YBD=2892 YBD=2893 YBD=2893 YHG=2858>We YHG=2862>prefer YHG=2862>to YHG=2863>suggest YHG=2863>that YHG=2872>x YHG=2863>is YHG=2862>inanimate YHG=2862>and YHG=2863>is YHG=2862>distributed XBD=1546XHG=901 XBD=1801 XBD=1908 XBD=2106 XBD=2215 XBD=2339 XBD=2445 XBD=2526 XHG=1320 XHG=1573 XHG=1829 XHG=1938 XHG=2136 XHG=2243 XHG=2367 XHG=2476 YBD=2906 YBD=2899 YBD=2898 YHG=2868>heemolysin YHG=2868>production YHG=2877>was YHG=2869>variable YHG=2870>and YHG=2879>soon YHG=2869>lost YHG=2878>on XBD=262 XHG=895 XBD=520 XBD=608 XBD=745 XBD=811 XBD=874 XBD=992 XBD=1079 XBD=1199 XBD=1267 XHG=90 XHG=284 XHG=542 XHG=630 XHG=768 XHG=831 XHG=1014 XHG=1100 XHG=1222 YBD=2937 YBD=2938 YBD=2939 YBD=2930 YBD=2931 YBD=2931 YHG=2901>generally YHG=2901>throughout YHG=2902>the YHG=2901>body, YHG=2910>or YHG=2902>at YHG=2902>least YHG=2902>the YHG=2902>skin, YHG=2901>of XBD=1565 XBD=1784 XBD=2047 XBD=2156 XBD=2449 XBD=2526 XHG=1319 XHG=1612 XHG=1817 XHG=2078 XHG=2191 XHG=2484 YBD=2943 YBD=2944 YBD=2938 YBD=2937 YBD=2936 YHG=2908>subculture YHG=2907>pigment YHG=2908>production YHG=2917>was YHG=2907>considerable YHG=2907>in ; XBD=220 XBD=407 XBD=519 XBD=849 XBD=908 XBD=1125 XBD=1263 XHG=89 XHG=252 XHG=442 XHG=668 XHG=934 XHG=1152 YBD=2968 YBD=2975 YBD=2969 YBD=2977 YBD=2970 YBD=2976 YBD=2969 that YHG=2938>certain YHG=2947>persons YHG=2940>and YHG=2940>impetigo YHG=2940>is YHG=2940>produced YHG=2941>when XBD=1460XHG=875 XBD=1650 XBD=1776 XBD=1984 XBD=2174 XBD=2460 XBD=2526 XHG=1317 XHG=1485 XHG=1675 XHG=1802 XHG=2010 XHG=2216 XHG=2487 YBD=2975 YBD=2976 YBD=2982 YBD=2983 YBD=2974 YHG=2946>strains ; YHG=2945>isolated YHG=2945>from YHG=2946>circinate YHG=2947>lesions YHG=2945>coagulation YHG=2945>of XBD=202 XBD=402 XBD=455 XBD=695 XBD=799 XBD=888 XBD=996 XBD=1062 XBD=1104 XBD=1263 XHG=67 XHG=224 XHG=423 XHG=477 XHG=717 XHG=821 XHG=1012 XHG=1079 XHG=1125 YBD=3012 YBD=3014 YBD=3009 YBD=3008 YBD=3008 YBD=3015 YHG=2974>Staph. YHG=2986>pyogenes YHG=2978>is YHG=2979>inoculated YHG=2979>into YHG=2979>the YHG=2979>skin YHG=2979>of YHG=2988>a YHG=2987>person XBD=1450XHG=909 XBD=1570 XBD=1666 XBD=1791 XBD=1924 XBD=1986 XBD=2147 XBD=2293 XBD=2410 XBD=2525 XHG=1315 XHG=1472 XHG=1588 XHG=1686 XHG=1811 XHG=1944 XHG=2003 XHG=2168 XHG=2312 XHG=2433 YBD=3022 YBD=3014 YBD=3013 YHG=2985>litmus YHG=2985>milk YHG=2993>was YHG=2981>most YHG=2985>rapid YHG=2985>in YHG=2985>strains YHG=2984>which YHG=2993>were YHG=2984>slow XBD=170 XHG=842 XBD=221 XBD=310 XBD=453 XBD=542 XBD=607 XBD=825 XBD=885 XBD=1095 XBD=1262 XHG=89 XHG=186 XHG=271 XHG=327 XHG=472 XHG=559 XHG=625 XHG=903YBD=3043 XHG=1113 YBD=3044 YBD=3045 YBD=3048 YBD=3054 YBD=3046 YBD=3053 YBD=3046 YHG=3014>with YHG=3024>x. YHG=3016>It YHG=3017>would YHG=3018>not YHG=3018>be YHG=3017>profitable YHG=3018>to YHG=3017>speculate YHG=3017>further XBD=1744 XHG=1319 YHG=3022>mannite-fermenters. XBD=2044 XBD=2141 XBD=2202 XBD=2377 XBD=2524 XHG=1941 XHG=2063 XHG=2163 XHG=2223 XHG=2398 YBD=3053 YBD=3051 YBD=3052 YBD=3059 YHG=3024>albus YHG=3032>was YHG=3022>of YHG=3022>various YHG=3022>types, XBD=123 XBD=181 XBD=265 XBD=422 XBD=488 XBD=582 XBD=865 XBD=909 XBD=1025 XBD=1087 XBD=1262 XHG=89 XHG=142 XHG=201 XHG=286 XHG=443 XHG=504 XHG=603 XHG=929 XHG=1044 XHG=1108 YBD=3081 YBD=3081 YBD=3083 YBD=3085 YBD=3093 YBD=3084 YBD=3085 YBD=3085 YBD=3091 YHG=3059>as YHG=3053>to YHG=3053>the YHG=3055>nature YHG=3055>of YHG=3056>this YHG=3056>hypothetical YHG=3064>x YHG=3056>than YHG=3056>to YHG=3055>suggest XBD=1342XHG=885 XBD=1443 XBD=1512 XBD=1664 XBD=1785 XBD=2210 XBD=2526 XHG=1319 XHG=1369 XHG=1472 XHG=1539 XHG=1689 XHG=1816 XHG=2262 YBD=3090 YBD=3099 YBD=3097 YHG=3071>a YHG=3062>few YHG=3061>of YHG=3061>which YHG=3070>were YHG=3061>coagulase-positive. YHG=3061>Streptococcus XBD=145 XBD=367 XBD=424 XBD=469 XBD=595 XBD=635 XBD=858 XBD=1006 XBD=1068 XBD=1260 XHG=89 XHG=156 XHG=380 XHG=436 XHG=481 XHG=612 XHG=875 XHG=1024 XHG=1080 YBD=3119 YBD=3129 YBD=3122 YBD=3123 YBD=3131 YBD=3131 YBD=3123 YBD=3130 YHG=3089>the YHG=3092>possibility YHG=3093>of YHG=3094>it YHG=3094>being YHG=3103>a YHG=3094>particular YHG=3094>degree YHG=3094>of YHG=3093>susceptiXBD=1565XHG=651 XBD=1672 XBD=1752 XBD=1875 XBD=2051 XBD=2291 XBD=2527 XHG=1321 XHG=1576 XHG=1684 XHG=1764 XHG=1889 XHG=2064 XHG=2330 YBD=3136 YBD=3137 YBD=3129 YBD=3128 YBD=3135 YHG=3099>hcemolyticus YHG=3109>gave YHG=3099>the YHG=3100>usual YHG=3100>cultural YHG=3098>characters. YHG=3098>Grouping XBD=188 XBD=249 XBD=487 XBD=569 XBD=758 XBD=818 XBD=937 XBD=1120 XBD=1261 XHG=88 XHG=208 XHG=269 XHG=503 XHG=584 XHG=773 XHG=958 XHG=1140 YBD=3165 YBD=3159 YBD=3169 YBD=3162 YBD=3162 YBD=3162 YHG=3125>bility YHG=3138>or YHG=3131>immunity, YHG=3133>the YHG=3142>presence YHG=3133>of YHG=3142>some YHG=3133>unusual YHG=3133>metaXBD=1398XHG=833 XBD=1515 XBD=1686 XBD=1779 XBD=1900 XBD=2001 XBD=2067 XBD=2158 XBD=2338 XBD=2461 XBD=2527 XHG=1319 XHG=1424 XHG=1541 XHG=1710 XHG=1803 XHG=1924 XHG=2028 XHG=2091 XHG=2183 XHG=2363 XHG=2487 YBD=3175 YBD=3168 YBD=3169 YBD=3167 YBD=3172 YBD=3166 YHG=3148>was YHG=3139>only YHG=3138>carried YHG=3138>out YHG=3139>with YHG=3139>two YHG=3138>of YHG=3138>the YHG=3136>strains, YHG=3137>both YHG=3137>of XBD=193 XHG=890 XBD=249 XBD=330 XBD=507 XBD=568 XBD=682 XBD=875 XBD=981 XBD=1210 XHG=88 XHG=208 XHG=265 XHG=346 XHG=524 XHG=579 XHG=699 XHG=997 YBD=3196 YBD=3197 YBD=3198 YBD=3201 YBD=3200 YBD=3200 YHG=3163>bolite YHG=3177>or YHG=3169>the YHG=3170>absence YHG=3172>of YHG=3180>some YHG=3171>essential YHG=3170>food YHG=3170>substance. XBD=1444 XBD=1569 XBD=1721 XBD=1799 XBD=2015 XBD=2156 XBD=2399 XBD=2525 XHG=1318 XHG=1472 XHG=1601 XHG=1753 XHG=1856 XHG=2046 XHG=2187 XHG=2429 YBD=3214 YBD=3207 YBD=3205 YBD=3212 YBD=3206 YHG=3177>which YHG=3186>were YHG=3185>group YHG=3179>A. YHG=3178>Various YHG=3176>other YHG=3175>organisms YHG=3185>were XBD=173 XBD=275 XBD=312 XBD=388 XBD=446 XBD=579 XBD=668 XBD=868 XBD=936 XBD=1022 XBD=1105 XBD=1260 XHG=130 XHG=185 XHG=288 XHG=325 XHG=402 XHG=456 XHG=592 XHG=681 XHG=950 XHG=1033 XHG=1117 YBD=3234 YBD=3236 YBD=3237 YBD=3245 YBD=3238 YBD=3238 YBD=3238 YHG=3205>In YHG=3207>such YHG=3216>a YHG=3217>sea YHG=3209>of YHG=3209>doubt YHG=3209>and YHG=3209>difficulty YHG=3218>we YHG=3218>can YHG=3209>but YHG=3209>restate XBD=1450XHG=880 XBD=1548 XBD=1641 XBD=1891 XBD=2023 XBD=2086 XBD=2222 XBD=2527 XHG=1317 XHG=1475 XHG=1571 XHG=1663 XHG=1915 XHG=2042 XHG=2109 XHG=2246 YBD=3250 YBD=3245 YBD=3252 YBD=3243 YBD=3244 YHG=3215>found, YHG=3215>but YHG=3215>not YHG=3216>sufficiently YHG=3215>often YHG=3214>to YHG=3214>merit YHG=3214>consideration

" " " " "

XBD=2526XHG=831 XBD=153 XBD=417 XBD=597 XBD=870 XBD=1182 XBD=1262 XBD=1485 XBD=1520 XBD=1658 XBD=1764 XBD=1909 XBD=2060 XBD=2152 XBD=2322 XBD=2378 XHG=127 XHG=176 XHG=438 XHG=888YBD=3321 XHG=1203 XHG=1368 XHG=1503 XHG=1536 XHG=1673 XHG=1781 XHG=1927 XHG=2074 XHG=2169 XHG=2337 XHG=2395 YBD=3318 YBD=3328 YBD=3329 YBD=3322 YBD=3321 YBD=3329 YBD=3327 YBD=3320 YBD=3328 hemolytic YHG=3291>1. YHG=3291>Streptococci, YHG=3293>whether YHG=3303>or YHG=3293>non-hsemolytic, YHG=3302>are YHG=3292>Table YHG=3300>i YHG=3293>shows YHG=3292>that YHG=3293>Staph. YHG=3300>aureus YHG=3299>was YHG=3291>present YHG=3291>in YHG=3292>nearly XBD=199 XHG=612 XBD=245 XBD=347 XBD=426 XBD=545 XBD=601 XBD=789 XBD=1435 XBD=1560 XBD=1676 XBD=1951 XBD=2070 XBD=2167 XBD=2355 XBD=2422 XBD=2528 XHG=87 XHG=214 XHG=255 XHG=363 XHG=443 XHG=561 XHG=1320 XHG=1461 XHG=1585 XHG=1701 XHG=1974 XHG=2097 XHG=2189 XHG=2380 XHG=2446 YBD=3365 YBD=3357 YBD=3363 YBD=3358 YBD=3359 YBD=3367 YBD=3366 YBD=3367 YBD=3359 YBD=3358 YBD=3360 YHG=3329>rarely, YHG=3329>if YHG=3339>ever, YHG=3331>the YHG=3340>cause YHG=3332>of YHG=3331>impetigo. YHG=3339>every YHG=3339>case, YHG=3330>that YHG=3329>streptococci YHG=3338>were YHG=3329>not YHG=3329>isolated YHG=3329>in YHG=3330>this XBD=153 XHG=730 XBD=290 XBD=469 XBD=513 XBD=639 XBD=715 XBD=906 XBD=1096 XBD=1151 XBD=1209 XBD=1263 XBD=1528 XBD=1662 XBD=1726 XBD=1856 XBD=1918 XBD=2009 XBD=2128 XBD=2325 XBD=2400 XBD=2526 XHG=125 XHG=175 XHG=304 XHG=482 XHG=526 XHG=652 XHG=922YBD=3397 XHG=1110 XHG=1161 XHG=1224 XHG=1319 XHG=1549 XHG=1682 XHG=1747 XHG=1875 XHG=1940 XHG=2032 XHG=2148 XHG=2346 XHG=2423 YBD=3394 YBD=3402 YBD=3404 YBD=3405 YBD=3396 YBD=3399 YBD=3397 YBD=3404 YBD=3405 YBD=3398 YHG=3368>2. YHG=3367>Staph. YHG=3377>pyogenes YHG=3370>is YHG=3370>either YHG=3370>the YHG=3370>causative YHG=3369>organism YHG=3369>of YHG=3369>all YHG=3378>or YHG=3367>particular YHG=3369>series YHG=3378>as YHG=3369>often YHG=3377>as YHG=3368>has YHG=3367>been YHG=3368>reported YHG=3369>by YHG=3378>some XBD=120 XBD=192 XBD=379 XBD=440 XBD=553 XBD=614 XBD=797 XBD=858 XBD=977 XBD=1046 XBD=1261 XHG=86 XHG=134 XHG=211 XHG=399 XHG=458 XHG=574 XHG=632 XHG=819 XHG=1000 XHG=1067 YBD=3431 YBD=3433 YBD=3442 YBD=3444 YBD=3435 YBD=3443 YBD=3434 YBD=3443 YHG=3404>of YHG=3406>the YHG=3406>majority YHG=3409>of YHG=3416>cases YHG=3407>of YHG=3407>impetigo YHG=3416>or YHG=3408>plays YHG=3416>an YHG=3408>important XBD=1592XHG=878 XBD=1893 XBD=2024 XBD=2126 XBD=2237 XBD=2369 XBD=2471 XBD=2527 XHG=1318 XHG=1619 XHG=1919 XHG=2048 XHG=2147 XHG=2262 XHG=2392 XHG=2503 YBD=3444 YBD=3442 YBD=3435 YBD=3436 YBD=3438 YBD=3437 YHG=3406>investigators YHG=3406>(Cruickshank YHG=3406>1941) YHG=3406>and YHG=3406>that YHG=3407>there YHG=3417>was YHG=3418>a XBD=158 XBD=206 XBD=282 XBD=459 XBD=515 XBD=589 XBD=746 XHG=87 XHG=172 XHG=221 XHG=298 XHG=475 XHG=526 YBD=3477 YBD=3471 YBD=3481 YBD=3473 YHG=3446>part YHG=3443>in YHG=3445>the YHG=3445>aetiology YHG=3446>of YHG=3446>the YHG=3445>disease. XBD=1522XHG=604 XBD=1613 XBD=1823 XBD=1883 XBD=2008 XBD=2239 XBD=2299 XBD=2412 XBD=2530 XHG=1320 XHG=1541 XHG=1632 XHG=1846 XHG=1901 XHG=2029 XHG=2258 XHG=2318 XHG=2430 YBD=3481 YBD=3474 YBD=3482 YBD=3475 YBD=3476 YHG=3444>relatively YHG=3446>low YHG=3446>incidence YHG=3445>of YHG=3444>these YHG=3445>organisms YHG=3446>in YHG=3446>fluid YHG=3447>from

" XBD=1162 XBD=148 XBD=291 XBD=432 XBD=504 XBD=744 XBD=802 XHG=89 XHG=164 XHG=308 XHG=448 XHG=523 XHG=760 XHG=911 YBD=3272 YBD=3274 YBD=3276 YBD=3277 YBD=3276 YHG=3249>our YHG=3244>beliefs YHG=3246>which YHG=3256>we YHG=3247>summarise YHG=3248>in YHG=3248>two YHG=3248>statements : " XBD=894 XBD=1425XHG=817 XHG=1322 YBD=3283 YHG=3254>here.

Staph.

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