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Indirect procedures on the larynx and pharynx in the lab
Otolaryngology Head and Neck Surgery Volume 112 Number 5
Instruction Courses-- Monday
will be discussed, making use of representative video recordings. To date, all occluded ears remain relieved of their BPPV with follow-up times as long as 7 years.
COURSE 2735- i One-period course ($20)
Room NOCC-98 3:00-4:00
Indirect Procedures on the Larynx and Pharynx in the Lab R.W. BASTIAN,MD M a y w o o d , Ill.
With the availability of office videoendoscopy, topical anesthesia, and short-acting intravenous sedation, indirect procedures on the larynx and pharynx can substitute in many cases for a trip to the operating room. For example, many squamous cell carcinomas in these sites can be fully staged and biopsied outside of an operating room setting thereby obviating the need for preliminary direct laryngoscopy for obtaining tissue and treatment planning. Laryngeal injections of Teflon, gelfoam, botulinum toxin, collagen, and steroids can be performed indirectly on awake, seated patients on a routine basis. Finally, aggressive nonoperative diagnostics for entities such as subglottic and tracheal stenosis can be commonplace. The necessary equipment will be reviewed, and technical "tips and pointers," including for sedation, which make indirect procedures on the larynx in an office setting accessible to the interested otolaryngologist will be elaborated. Numerous videotaped examples of actual procedures of the types mentioned above will be shown.
COURSE 2736-2 Two-period course ($40)
Room NOCC-99 3:00-5:15
A d v a n c e d Computer Graphics and Multimedia Presentations EVAN S. BATES,MD, JOHN HOUCK, MD, KEITH F. CLARK, MD, and SUSAN RODMAN, PhD Dallas, Texas, O k l a h o m a City, Okla., a n d Morgantown, W.Va.
Educational objectives: To create computer presentations that incorporate sound and photographic and video images and to have an understanding of multimedia capabilities.
The use of graphics software has enabled individuals to produce presentation slides easily and inexpensively. For individuals with computer experience, more detailed knowledge of available hardware and software can greatly improve the quality of presentation slides. The integration of clip-art, scanned images, and templates can be used to create a superior presentation. Our course will acquaint the computer user with the components of a computer slidemaking system and evaluate the various hardware and software options of such a system. In going beyond the scope
P 101
of the beginner computer slide-making course, our discussion will also focus on the advanced use of film recorders, image scanners, slide service bureaus, and slide-making software in creating an effective slide presentation. In addition to a comprehensive hands-on demonstration of a current slide-making software program, we will demonstrate the uses of multimedia in presentations. Integrating video, sound, and photographic images can produce an extremely sophisticated and visually informative presentation. A comprehensive course manual will be distributed to each participant.
COURSE 2737-I One-period course ($20)
Room NOCC-100 3:00-4:00
Genetics of H e a d and N e c k Cancer: Advances in Molecular Research MICHAEL S. BENNINGER,MD, DANIELVANDYKE, PhD, CAROL BRADFORD,MD, and THOMAS CAREY, PhD Detroit a n d Ann Arbor, Mich,
Educational objectives: To be familiar with cytogenetic and molecular data on early, advanced, recurrent metastatic head and neck cancers, and to understand common methodologies for genetic and molecular assessment including fluorescence in situ hybridization, microsatellite repeat polymorphisms, and polymerase chain reaction, as well as the role of human papilloma virus in squamous cell carcinoma (SCC).
Further understanding of the genetics of cancers will likely lead to improved assessment and treatment. Cytogenetic analysis of head and neck SCCs has helped to clarify the early genetic changes that seem to occur and will assist directed molecular investigation. Key genetic changes in SCC include deletions, which appear to be associated with the loss of expression of tumor suppression genes, and duplication or amplification of genetic material. The cytogenetic changes are responsible for alterations in gene expression within the tumor cells. Experience with other cancers has shown that recurrent genetic and cytogenetic changes can lead to gene identification that may be utilized for genetic screening, behavioral modifications, and gene-directed and genetic therapy. This course will review cytogenetic and molecular data on early, advanced, recurrent metastatic head and neck SCC. Common methodologies for genetic and molecular assessment will be discussed, including fluorescence in sire hybridization, cytogenetic analysis, microsatellite repeat polymorphisms, and polymerase chain reaction. The roles of gains and losses of genetic material will be discussed. Areas of current research on genetic analysis, individual losses and gains, and the role of human papilloma virus will be presented. Current research and future direction for the molecular genetic assessment of these cancers and how such investigation will aid understanding and may direct treatment of head and neck tumors will be presented along with
Instruction Courses-- Monday
will be discussed, making use of representative video recordings. To date, all occluded ears remain relieved of their BPPV with follow-up times as long as 7 years.
COURSE 2735- i One-period course ($20)
Room NOCC-98 3:00-4:00
Indirect Procedures on the Larynx and Pharynx in the Lab R.W. BASTIAN,MD M a y w o o d , Ill.
With the availability of office videoendoscopy, topical anesthesia, and short-acting intravenous sedation, indirect procedures on the larynx and pharynx can substitute in many cases for a trip to the operating room. For example, many squamous cell carcinomas in these sites can be fully staged and biopsied outside of an operating room setting thereby obviating the need for preliminary direct laryngoscopy for obtaining tissue and treatment planning. Laryngeal injections of Teflon, gelfoam, botulinum toxin, collagen, and steroids can be performed indirectly on awake, seated patients on a routine basis. Finally, aggressive nonoperative diagnostics for entities such as subglottic and tracheal stenosis can be commonplace. The necessary equipment will be reviewed, and technical "tips and pointers," including for sedation, which make indirect procedures on the larynx in an office setting accessible to the interested otolaryngologist will be elaborated. Numerous videotaped examples of actual procedures of the types mentioned above will be shown.
COURSE 2736-2 Two-period course ($40)
Room NOCC-99 3:00-5:15
A d v a n c e d Computer Graphics and Multimedia Presentations EVAN S. BATES,MD, JOHN HOUCK, MD, KEITH F. CLARK, MD, and SUSAN RODMAN, PhD Dallas, Texas, O k l a h o m a City, Okla., a n d Morgantown, W.Va.
Educational objectives: To create computer presentations that incorporate sound and photographic and video images and to have an understanding of multimedia capabilities.
The use of graphics software has enabled individuals to produce presentation slides easily and inexpensively. For individuals with computer experience, more detailed knowledge of available hardware and software can greatly improve the quality of presentation slides. The integration of clip-art, scanned images, and templates can be used to create a superior presentation. Our course will acquaint the computer user with the components of a computer slidemaking system and evaluate the various hardware and software options of such a system. In going beyond the scope
P 101
of the beginner computer slide-making course, our discussion will also focus on the advanced use of film recorders, image scanners, slide service bureaus, and slide-making software in creating an effective slide presentation. In addition to a comprehensive hands-on demonstration of a current slide-making software program, we will demonstrate the uses of multimedia in presentations. Integrating video, sound, and photographic images can produce an extremely sophisticated and visually informative presentation. A comprehensive course manual will be distributed to each participant.
COURSE 2737-I One-period course ($20)
Room NOCC-100 3:00-4:00
Genetics of H e a d and N e c k Cancer: Advances in Molecular Research MICHAEL S. BENNINGER,MD, DANIELVANDYKE, PhD, CAROL BRADFORD,MD, and THOMAS CAREY, PhD Detroit a n d Ann Arbor, Mich,
Educational objectives: To be familiar with cytogenetic and molecular data on early, advanced, recurrent metastatic head and neck cancers, and to understand common methodologies for genetic and molecular assessment including fluorescence in situ hybridization, microsatellite repeat polymorphisms, and polymerase chain reaction, as well as the role of human papilloma virus in squamous cell carcinoma (SCC).
Further understanding of the genetics of cancers will likely lead to improved assessment and treatment. Cytogenetic analysis of head and neck SCCs has helped to clarify the early genetic changes that seem to occur and will assist directed molecular investigation. Key genetic changes in SCC include deletions, which appear to be associated with the loss of expression of tumor suppression genes, and duplication or amplification of genetic material. The cytogenetic changes are responsible for alterations in gene expression within the tumor cells. Experience with other cancers has shown that recurrent genetic and cytogenetic changes can lead to gene identification that may be utilized for genetic screening, behavioral modifications, and gene-directed and genetic therapy. This course will review cytogenetic and molecular data on early, advanced, recurrent metastatic head and neck SCC. Common methodologies for genetic and molecular assessment will be discussed, including fluorescence in sire hybridization, cytogenetic analysis, microsatellite repeat polymorphisms, and polymerase chain reaction. The roles of gains and losses of genetic material will be discussed. Areas of current research on genetic analysis, individual losses and gains, and the role of human papilloma virus will be presented. Current research and future direction for the molecular genetic assessment of these cancers and how such investigation will aid understanding and may direct treatment of head and neck tumors will be presented along with