- Email: [email protected]
INFANT INTOLERANCE TO COW'S MILK.
1386 If a in the method best calculated to attain this end. farcical and, perhaps, absurd analogy, which nevertheless appeals to patients, may be allowed, their attitude towards their war experiences is that of a young child who has been told by a foolish nurse that a jack-in-the-box contains a bogey-man with power to jump out and hurt him if he is troublesome. If left alone with this and his toys-and it has to be imagined that the hook which keeps the lid of the box down is broken-the child, afraid of the bogey’s eruption, keeps the lid down by the force of his hand. All goes more or less well until fatigue and drowsiness supervene, whereon the hand drops off, the doll jumps out, and the child is terrorstruck. (It is significant how many patients tell one they wake with a start, sweating and palpitating, just as sleep overtakes them with its suspension of the power of the will to act as censor.) Will it be said that in such a case it would be at " variance with common sense " to take the child to the dreaded box, to open it and to show him that the awesome bogey is only a harmless doll, and are not war memories equally harmless, if he will only realise it, to a patient safely back in England ? The child, once realising the innocuous nature of his bugbear, forgets it as soon as a new toy is given him, not because he wishes to drive it from his memory, but simply because it takes its proper place in his scheme of things, and has no particular emotional tone associated with it. So with the war neurotic; one aims at enabling him to forget his experiences by their taking their rightful place as memories admittedly terrible, but not worth running away from, and powerless to hurt him. There is indubitable evidence that is genuinely overcome, the battle-dreams when repression diminish, the patient sleeps better and soon begins to mend.
My reason for trespassing on your space is that, unfortunately, the advice invariably given to these patients is to forget the war and all about it, no doubt excellent advice if it worked. The fact bhat 20 months after the armistice and perhaps three, four, or even five years after the breakdown the men are still uncured shows sufficiently that it does not work. I am, Sir, yours faithfully, R. L. GAMLEN. Brinnington Neurological Hospital, Stockport, June 15th, 1920.
THE SURGICAL TREATMENT OF PROLAPSE OF THE UTERUS AND VAGINA. To the Editor of THE LANCET.
I am inclined to think that by the second method quinine becomes partially isomerised to quinidin. This will be difficult to prove chemically, but it seems to me that it might, perhaps, be advisable to try such a method of activating " quinine, since it is possible that it might possess the therapeutical advantages indicated by the observations made by Major Acton. I am, Sir, yours faithfully, "
M.
NIERENSTEIN, D.Sc., Ph.D., Lecturer in Bio-chemistry.
University of Bristol, June 15th, 1920.
THE POSITION OF VETERINARY SCIENCE. To the Editor of THE LANCET.
SIR,-I am sure that those who are really interested in the progress of veterinary science will be very grateful for the exceedingly sane leader in your issue of June 19th, which is in pleasant contrast to the semihysterical and partly erroneous lucubrations that have recently appeared in the daily press. There is, however, one omission to which I should like to draw your You do not state that the University of attention. Edinburgh confers the degrees of B.Sc. and D.Sc. in veterinary science. The ordinance under which these degrees are conferred came into operation in 1911, and the number of students taking the necessary additional courses of instruction now forms a considerable percentage of the Edinburgh veterinary students. I might add, also, that the Royal College of Veterinary Surgeons- has recently instituted a diploma in veterinary State medicine (D.V.S.M.), the first examination for which is to be held in Edinburgh during next week. I am, Sir, yours faithfully, O. CHARNOCK BRADLEY, Principal, Royal (Dick) Veterinary College, Edinburgh. June 19th, 1920. INFANT INTOLERANCE TO COW’S MILK. To the Editor
of
THE LANCET.
SIR,—The note from the Paris Correspondent of THE LANCET in your issue of June 12th on anaphylactic vomiting in an infant reminds me of a case of infant SIR,-I have read Dr. Blair Bell’s letter. I regret intolerance to cow’s milk which was under my care. very much his invective, which I do not answer. The This child was born on Jan. 31st, 1913. He was breastaim of my first letter was to further science ; Dr. fed from birth. During the third month an attempt Blair Bell’s present letter adds nothing to the subject. was made to begin feeding him with diluted sterilised I have neither the time nor the inclination to exchange cow’s under my supervision. Within a milk, prepared vituperation; but this does not imply- that I have few minutes he vomited the feed and came out in a views. alter received any reason to my profuse urticarial rash. The gastric disturbance lasted I am, Sir. yours faithfully, for a good many hours. The same thing happened R. H. PARAMORE. Rngby, June 19th, 1920. with diluted pasteurised cow’s milk from another dairy, which was tried a few days later, and a third attempt THE CHEMO-THERAPEUTICS OF QUININE. in July was no more successful. Cow’s milk of varying strengths, including solutions of dried milk, was tried To the Editor of THE LANCET. from time to time during the summer, but every attempt SIR,—The recent publication of Major H. W. Acton, vomiting, rash, and gastric upset. In August I.M.S., which appeared in THE LANCET of June 12th, produced" we tried goat’s milk with complete success, and for the marks an important progress in the chemo-therapeutics next month the child had breast feeds and goat’s milk of quinine. His observations that whilst the laevo-half of each. On Sept. 14th, 1913, he was weaned rotatory alkaloid quinine is a specific for the malignant and was fed wholly on goat’s milk until March lst, 1914, tertian parasite its dextrorotatory isomeride quinidin is when for the first time he began to tolerate diluted the best alkaloid for the benign tertian parasite deserve cow’s milk in very small quantities. The amount of the greatest attention of those engaged in the treatment the cow’s milk was gradually increased, and at the end of malaria, since they open a new field for research on of a month he could take undiluted cow’s milk without those lines. any ill-effect. Thenceforward there was never any In view of the importance of these observations I hope intolerance to cow’s milk. It appears that a maternal I may be permitted to describe a few chemical experiaunt of this child was brought up on goat’s milk ments which I was unfortunately unable to complete ’’because she couldn’t digest cow’s milk " ; there is no prior to my being demobilised from the army. These other relevant family history. observations may be of some use to others. I am, Sir, yours faithfully, (1) If a 10 per cent. solution of quinine sulphate is heated June 19th, 1920. London, M.B., B.CH. for one to two hours the solution turns dark. Its specific rotation falls from - 1640 to - 43°. This depression of the rotation is probably due to the formation of quintoxin, as SOCIETY FOR THE PREVENTION OF VENEREAL can be shown by the test described by v. Miller and Rhode DISEASE.-We have received a letter from Mr. Wansey for this substance (Berichte der deutschen chemischen Gesell- Bayly, honorary secretary of this society, in which he states schaft, 1895, vol. xxviii., pp. 1058 ; 1900, vol. xxxiii., pp. 3223 ; that the Executive Committee of the Society, at its last compare also Scholz, Berichte der deutschen pharmacologischen meeting, resolved that notice should be sent to all the medical members of the Executive, Medical, and Propaganda Gesellsehaft, 1908, vol. xviii., pp. 44). (2) If, however, a 10 per cent. solution of quinine is heated Committees of the National Council for Combating Venereal for the same length of time and hydrogen or carbon dioxide Diseases, and to the medical press, announcing the resignais passed through the boiling solution all the time, the tion from the National Council of Dr. Rayner D. Batten, rotation alters from - 16411 to + 58°. The solution does not Mr. E. T. Burke, Sir Bryan Donkin, Sir Frederick Mott, alter in colour and is free from quintoxin. Sir Humphry Rolleston, and Dr. J. H. Sequeira.
My reason for trespassing on your space is that, unfortunately, the advice invariably given to these patients is to forget the war and all about it, no doubt excellent advice if it worked. The fact bhat 20 months after the armistice and perhaps three, four, or even five years after the breakdown the men are still uncured shows sufficiently that it does not work. I am, Sir, yours faithfully, R. L. GAMLEN. Brinnington Neurological Hospital, Stockport, June 15th, 1920.
THE SURGICAL TREATMENT OF PROLAPSE OF THE UTERUS AND VAGINA. To the Editor of THE LANCET.
I am inclined to think that by the second method quinine becomes partially isomerised to quinidin. This will be difficult to prove chemically, but it seems to me that it might, perhaps, be advisable to try such a method of activating " quinine, since it is possible that it might possess the therapeutical advantages indicated by the observations made by Major Acton. I am, Sir, yours faithfully, "
M.
NIERENSTEIN, D.Sc., Ph.D., Lecturer in Bio-chemistry.
University of Bristol, June 15th, 1920.
THE POSITION OF VETERINARY SCIENCE. To the Editor of THE LANCET.
SIR,-I am sure that those who are really interested in the progress of veterinary science will be very grateful for the exceedingly sane leader in your issue of June 19th, which is in pleasant contrast to the semihysterical and partly erroneous lucubrations that have recently appeared in the daily press. There is, however, one omission to which I should like to draw your You do not state that the University of attention. Edinburgh confers the degrees of B.Sc. and D.Sc. in veterinary science. The ordinance under which these degrees are conferred came into operation in 1911, and the number of students taking the necessary additional courses of instruction now forms a considerable percentage of the Edinburgh veterinary students. I might add, also, that the Royal College of Veterinary Surgeons- has recently instituted a diploma in veterinary State medicine (D.V.S.M.), the first examination for which is to be held in Edinburgh during next week. I am, Sir, yours faithfully, O. CHARNOCK BRADLEY, Principal, Royal (Dick) Veterinary College, Edinburgh. June 19th, 1920. INFANT INTOLERANCE TO COW’S MILK. To the Editor
of
THE LANCET.
SIR,—The note from the Paris Correspondent of THE LANCET in your issue of June 12th on anaphylactic vomiting in an infant reminds me of a case of infant SIR,-I have read Dr. Blair Bell’s letter. I regret intolerance to cow’s milk which was under my care. very much his invective, which I do not answer. The This child was born on Jan. 31st, 1913. He was breastaim of my first letter was to further science ; Dr. fed from birth. During the third month an attempt Blair Bell’s present letter adds nothing to the subject. was made to begin feeding him with diluted sterilised I have neither the time nor the inclination to exchange cow’s under my supervision. Within a milk, prepared vituperation; but this does not imply- that I have few minutes he vomited the feed and came out in a views. alter received any reason to my profuse urticarial rash. The gastric disturbance lasted I am, Sir. yours faithfully, for a good many hours. The same thing happened R. H. PARAMORE. Rngby, June 19th, 1920. with diluted pasteurised cow’s milk from another dairy, which was tried a few days later, and a third attempt THE CHEMO-THERAPEUTICS OF QUININE. in July was no more successful. Cow’s milk of varying strengths, including solutions of dried milk, was tried To the Editor of THE LANCET. from time to time during the summer, but every attempt SIR,—The recent publication of Major H. W. Acton, vomiting, rash, and gastric upset. In August I.M.S., which appeared in THE LANCET of June 12th, produced" we tried goat’s milk with complete success, and for the marks an important progress in the chemo-therapeutics next month the child had breast feeds and goat’s milk of quinine. His observations that whilst the laevo-half of each. On Sept. 14th, 1913, he was weaned rotatory alkaloid quinine is a specific for the malignant and was fed wholly on goat’s milk until March lst, 1914, tertian parasite its dextrorotatory isomeride quinidin is when for the first time he began to tolerate diluted the best alkaloid for the benign tertian parasite deserve cow’s milk in very small quantities. The amount of the greatest attention of those engaged in the treatment the cow’s milk was gradually increased, and at the end of malaria, since they open a new field for research on of a month he could take undiluted cow’s milk without those lines. any ill-effect. Thenceforward there was never any In view of the importance of these observations I hope intolerance to cow’s milk. It appears that a maternal I may be permitted to describe a few chemical experiaunt of this child was brought up on goat’s milk ments which I was unfortunately unable to complete ’’because she couldn’t digest cow’s milk " ; there is no prior to my being demobilised from the army. These other relevant family history. observations may be of some use to others. I am, Sir, yours faithfully, (1) If a 10 per cent. solution of quinine sulphate is heated June 19th, 1920. London, M.B., B.CH. for one to two hours the solution turns dark. Its specific rotation falls from - 1640 to - 43°. This depression of the rotation is probably due to the formation of quintoxin, as SOCIETY FOR THE PREVENTION OF VENEREAL can be shown by the test described by v. Miller and Rhode DISEASE.-We have received a letter from Mr. Wansey for this substance (Berichte der deutschen chemischen Gesell- Bayly, honorary secretary of this society, in which he states schaft, 1895, vol. xxviii., pp. 1058 ; 1900, vol. xxxiii., pp. 3223 ; that the Executive Committee of the Society, at its last compare also Scholz, Berichte der deutschen pharmacologischen meeting, resolved that notice should be sent to all the medical members of the Executive, Medical, and Propaganda Gesellsehaft, 1908, vol. xviii., pp. 44). (2) If, however, a 10 per cent. solution of quinine is heated Committees of the National Council for Combating Venereal for the same length of time and hydrogen or carbon dioxide Diseases, and to the medical press, announcing the resignais passed through the boiling solution all the time, the tion from the National Council of Dr. Rayner D. Batten, rotation alters from - 16411 to + 58°. The solution does not Mr. E. T. Burke, Sir Bryan Donkin, Sir Frederick Mott, alter in colour and is free from quintoxin. Sir Humphry Rolleston, and Dr. J. H. Sequeira.