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Inflammation mechanisms and control
lmmuaochemistry, 1974, Vol. 1 I. p. 761. Pergamon Press. Printed in Great Britain
BOOK REVIEW Inflammation Mechanisms and C o n t r o b - E d i t e d by Irwin H. Lepow and Peter A. Ward. A c a demic Press, New York, 1972. 409 pp. $14.00. Inflammation is a complex set of reactions exhibited b y organisms in response to injury. It can be at the same time both protective and deleterious. Because a wide range of diseases of man may be a consequence of inflammation, much research has been aimed at the development of specific modulating agents. This book presents the proceedings of a multidisciptinary conference on inflammation held in June 1972 under the sponsorship of the Squibb Institute of Medical Research. The primary goal of the conference which was organized by Drs. Lepow and Ward, was to provide a statement of the current status of research on inflammation and to describe some of the newer approaches modifying the inflammatory response. Its 22 chapters focus on basic morphological and biochemical aspects of inflammation, chemical mediators of inflammation, immunopathology of inflammation, and alteration of the inflammatory response. Nearly all the chapters are written clearly and authoritatively with
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a good balance between background material, current data, interpretation and discussion. I was particularly stimulated by discussion of contractile events by G. Majno, cell membranes by M. L. Karnovsky and by Z. A. Cohn, cyclic AMP by C. W. Parker, and modulation of immune complex disease in experimental and clinical situations by W. T. Kniker, to mention just a few. Naturally, in a field as extensive as inflammation the breadth of the field that can be covered by such a conference must be limited. Nevertheless, I recommend this volume highly to anyone who wants up-to-date information on many important aspects of inflammation.
Department of Biochemistry The Johns Hopkins University School of Hygiene and Public Health Baltimore, Maryland 21205, U.S.A.
DAVID A. LEVY
BOOK REVIEW Inflammation Mechanisms and C o n t r o b - E d i t e d by Irwin H. Lepow and Peter A. Ward. A c a demic Press, New York, 1972. 409 pp. $14.00. Inflammation is a complex set of reactions exhibited b y organisms in response to injury. It can be at the same time both protective and deleterious. Because a wide range of diseases of man may be a consequence of inflammation, much research has been aimed at the development of specific modulating agents. This book presents the proceedings of a multidisciptinary conference on inflammation held in June 1972 under the sponsorship of the Squibb Institute of Medical Research. The primary goal of the conference which was organized by Drs. Lepow and Ward, was to provide a statement of the current status of research on inflammation and to describe some of the newer approaches modifying the inflammatory response. Its 22 chapters focus on basic morphological and biochemical aspects of inflammation, chemical mediators of inflammation, immunopathology of inflammation, and alteration of the inflammatory response. Nearly all the chapters are written clearly and authoritatively with
761
a good balance between background material, current data, interpretation and discussion. I was particularly stimulated by discussion of contractile events by G. Majno, cell membranes by M. L. Karnovsky and by Z. A. Cohn, cyclic AMP by C. W. Parker, and modulation of immune complex disease in experimental and clinical situations by W. T. Kniker, to mention just a few. Naturally, in a field as extensive as inflammation the breadth of the field that can be covered by such a conference must be limited. Nevertheless, I recommend this volume highly to anyone who wants up-to-date information on many important aspects of inflammation.
Department of Biochemistry The Johns Hopkins University School of Hygiene and Public Health Baltimore, Maryland 21205, U.S.A.
DAVID A. LEVY