- Email: [email protected]
Inside Back Cover: Notes to Authors
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Notes to Authors
Aims and Scope Antiviral Research publishes full-length original articles, short definitive papers and review articles (one per issue) pertaining to effective control of virus infections in animals and man as well as in plants or lower organisms. Its scope encompasses: –the mechanism of natural and acquired host resistance against virus infections, including a specific cellular resistance, interferons, cellular and humoral immunity in virus infections, chemotherapeutics which influence host resistance; –the development of new vaccines or novel forms of serotherapy against viral diseases, including virological characterization of vaccine strains or vaccine preparations; preparation and characterization of antiviral immunoglobulins; safety and efficiency assessment; field trials; –the development of new antiviral chemotherapeutics, including chemistry; in vitro activity; mechanism of action; activity in animal model systems; clinical trials.
For a full and complete Instructions to Authors, please refer to Antiviral Research, Vol. 67, No. 1, pp. v–vii. The instructions can also be found on the World Wide Web: access under http://www.elsevier.com
Editorial Policy The overriding criteria for publication are originality, high scientific quality, adequate documentation by experimental evidence and relevance to the aims and scope of the journal.
Electronic manuscripts: Electronic manuscripts have the advantage that there is no need for the rekeying of text, thereby avoiding the possibility of introducing errors and resulting in reliable and fast delivery of proofs.
Editors-in-Chief For the initial submission of manuscripts for consideration, hardcopies are sufficient. For the processing of accepted papers electronic versions are preferred. After final acceptance your disk plus three, final and exactly matching printed versions should be submitted together. Double density (DD) or high density (HD) diskettes (312) are acceptable. It is important that the file saved is in the native format of the wordprocessor program used. Label the disk with the name of the computer and wordprocessing package used, your name, and the name of the file on the disk. Further information may be obtained from the Publisher.
Erik De Clercq, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. Earl R. Kern, University of Alabama at Birmingham, 1600 7th Avenue South, CHB 128, Birmingham, AL 35233, USA. Richard J. Whitley, University of Alabama at Birmingham, 1600 7th Avenue South, CHB 303, Birmingham, AL 35233, USA. Associate Editor for Reviews George J. Galasso, National Institutes of Health (ret.), Health Sciences Consultant, 636 Crocus Drive, Rockville, MD 20850-2045, USA.
Authors in Japan please note: Upon request, Elsevier Japan will provide authors with a list of people who can check and improve the English of their paper (before submission). Please contact our Tokyo office: Elsevier Japan, 4F HigashiAzabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan, Tel.: (+81) (3) 5561 5037; Fax: (+81) (3) 5561 5047.
Editorial Board M. Baba, Kagoshima, Japan J. Balzarini, Leuven, Belgium D.L. Barnard, Logan, UT, USA D.I. Bernstein, Cincinnati, OH, USA K.K. Biron, Research Triangle Park, NC, USA N. Bischofberger, Foster City, CA, USA N. Bourne, Galveston, TX, USA M. Bray, NIAID/NIH, Bethesda, MD, USA R.W. Buckheit, Frederick, MD, USA L. Carrasco, Madrid, Spain T. Cihlar, Foster City, CA, USA J.C. Drach, Ann Arbor, MI, USA J. Este, Barcelona, Spain H.J. Field, Cambridge, UK W.R. Fleischmann, Galveston, TX, USA C. Flexner, Baltimore, MD, USA A. Fridland, Foster City, CA, USA G. Gosselin, Montpellier, France
P.D. Griffiths, London, UK L. Gubareva, Charlottesville, USA O. Haller, Freiburg, Germany F.G. Hayden, Charlottesville, VA, USA A. Holy´, Prague, Czech Republic J.W. Huggins, Fort Detrick, MD, USA C. Jonsson, Birmingham, AL, USA D. Kimberlin, Birmingham, Alabama, USA H. Kirchner, Lu¨beck, Germany B. Korba, Rockville, MD, USA J.J. Leary, Research Triangle Park, NC, USA G. Leroux-Roels, Gent, Belgium P. Ljungman, Stockholm, Sweden J.J. McSharry, Albany, NY, USA H. Mitsuya, Bethesda, MD, USA J. Neyts, Leuven, Belgium
¨ berg, Huddinge, Sweden B. O J. O’Connell, Pearl River, NY, USA A. Patick, San Diego, CA, USA C.-F. Perno, Rome, Italy R.B. Pollard, UC Davis, CA, USA R.F. Schinazi, Decatur, GA, USA J.A. Secrist III, Birmingham, AL, USA S. Shigeta, Fukushima, Japan R.W. Sidwell, Logan, UT, USA D.F. Smee, Logan, UT, USA S. Spruance, Salt Lake City, UT, USA C. Stafford-Gibbs, Foster City, CA, USA M. St. Clair, Research Triangle Park, NC, USA S. Vella, Rome, Italy A. Vlietinck, Antwerp, Belgium P. Wutzler, Jena, Germany N. Yamamoto, Tokyo, Japan F. Zoulim, Lyon, France
Author enquiries Authors can keep a track on the progress of their accepted article, and set up e-mail alerts informing them of changes to their manuscript’s status, by using the ‘‘Track a Paper’’ feature of Elsevier’s Author Gateway (http://www.authors. elsevier.com) Full details for the electronic submission of artwork can be obtained from http:/www.elsevier.com/locate/authorartwork/ Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication.
Antiviral Research has no page charges
Advertising information. Advertising orders and enquiries can be sent to: USA, Canada and South America: Mr Tino DeCarlo, The Advertising Department, Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710, USA; phone: (+1) (212) 633 3815; fax: (+1) (212) 633 3820; e-mail: [email protected]. Japan: The Advertising Department, Elsevier K.K., 4F Higashi-Azabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan; phone: (+81) (3) 5561 5037; fax: (+81) (3) 5561 5047; e-mail: [email protected]. Europe and ROW: Commercial Sales Department, Elsevier Ltd., The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK; phone: (+44) 1865 843016; fax: (+44) 1865 843976; e-mail: [email protected]
Publication information: Antiviral Research (ISSN 0166-3542). For 2005, volumes 65–68 are scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office nearest you or from this journal’s website (http://www.elsevier.com/locate/antiviral). Further information is available on this journal and other Elsevier products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of despatch. Orders, claims, and journal enquiries: please contact the Customer Service Department at the Regional Sales Office nearest you:
Tokyo: Elsevier, Customer Service Department, 4F Higashi-Azabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan; phone: (+81) (3) 5561 5037; fax: (+81) (3) 5561 5047; e-mail: [email protected]
USA mailing notice: Antiviral Research (ISSN 0166-3542) is published monthly by Elsevier B.V. (P.O. Box 211, 1000 AE Amsterdam, The Netherlands). Annual subscription price in the USA US$ 2143 (valid in North, Central and South America), including air speed delivery. Periodical postage rate paid at Jamaica, NY 11431. USA POSTMASTER: Send address changes to Antiviral Research, Publications Expediting Inc., 200 Meacham Ave, Elmont, NY 11003. AIRFREIGHT AND MAILING in the USA by Publications Expediting Inc., 200 Meacham Avenue, Elmont, NY 11003.
Singapore: Elsevier, Customer Service Department, 3 Killiney Road, #08-01 Winsland House I, Singapore 239519; phone: (+65) 63490222; fax: (+65) 67331510; e-mail: [email protected]
Printed in the United Kingdom
Orlando: Elsevier, Customer Service Department, 6277 Sea Harbor Drive, Orlando, FL 32887-4800, USA; phone: (+1) (877) 8397126 [toll free number for US customers], or (+1) (407) 3454020 [customers outside US]; fax: (+1) (407) 3631354; e-mail: [email protected] Amsterdam: Elsevier, Customer Service Department, PO Box 211, 1000 AE Amsterdam, The Netherlands; phone: (+31) (20) 4853757; fax: (+31) (20) 4853432; e-mail: [email protected]
* The paper used in this publication meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper) 1
ß 2005 Elsevier B.V. All rights reserved.
1 The paper in this publication meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper). *
0166-3542/2004/$20.00
||
Notes to Authors
Aims and Scope Antiviral Research publishes full-length original articles, short definitive papers and review articles (one per issue) pertaining to effective control of virus infections in animals and man as well as in plants or lower organisms. Its scope encompasses: –the mechanism of natural and acquired host resistance against virus infections, including a specific cellular resistance, interferons, cellular and humoral immunity in virus infections, chemotherapeutics which influence host resistance; –the development of new vaccines or novel forms of serotherapy against viral diseases, including virological characterization of vaccine strains or vaccine preparations; preparation and characterization of antiviral immunoglobulins; safety and efficiency assessment; field trials; –the development of new antiviral chemotherapeutics, including chemistry; in vitro activity; mechanism of action; activity in animal model systems; clinical trials.
For a full and complete Instructions to Authors, please refer to Antiviral Research, Vol. 67, No. 1, pp. v–vii. The instructions can also be found on the World Wide Web: access under http://www.elsevier.com
Editorial Policy The overriding criteria for publication are originality, high scientific quality, adequate documentation by experimental evidence and relevance to the aims and scope of the journal.
Electronic manuscripts: Electronic manuscripts have the advantage that there is no need for the rekeying of text, thereby avoiding the possibility of introducing errors and resulting in reliable and fast delivery of proofs.
Editors-in-Chief For the initial submission of manuscripts for consideration, hardcopies are sufficient. For the processing of accepted papers electronic versions are preferred. After final acceptance your disk plus three, final and exactly matching printed versions should be submitted together. Double density (DD) or high density (HD) diskettes (312) are acceptable. It is important that the file saved is in the native format of the wordprocessor program used. Label the disk with the name of the computer and wordprocessing package used, your name, and the name of the file on the disk. Further information may be obtained from the Publisher.
Erik De Clercq, Rega Institute, University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. Earl R. Kern, University of Alabama at Birmingham, 1600 7th Avenue South, CHB 128, Birmingham, AL 35233, USA. Richard J. Whitley, University of Alabama at Birmingham, 1600 7th Avenue South, CHB 303, Birmingham, AL 35233, USA. Associate Editor for Reviews George J. Galasso, National Institutes of Health (ret.), Health Sciences Consultant, 636 Crocus Drive, Rockville, MD 20850-2045, USA.
Authors in Japan please note: Upon request, Elsevier Japan will provide authors with a list of people who can check and improve the English of their paper (before submission). Please contact our Tokyo office: Elsevier Japan, 4F HigashiAzabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan, Tel.: (+81) (3) 5561 5037; Fax: (+81) (3) 5561 5047.
Editorial Board M. Baba, Kagoshima, Japan J. Balzarini, Leuven, Belgium D.L. Barnard, Logan, UT, USA D.I. Bernstein, Cincinnati, OH, USA K.K. Biron, Research Triangle Park, NC, USA N. Bischofberger, Foster City, CA, USA N. Bourne, Galveston, TX, USA M. Bray, NIAID/NIH, Bethesda, MD, USA R.W. Buckheit, Frederick, MD, USA L. Carrasco, Madrid, Spain T. Cihlar, Foster City, CA, USA J.C. Drach, Ann Arbor, MI, USA J. Este, Barcelona, Spain H.J. Field, Cambridge, UK W.R. Fleischmann, Galveston, TX, USA C. Flexner, Baltimore, MD, USA A. Fridland, Foster City, CA, USA G. Gosselin, Montpellier, France
P.D. Griffiths, London, UK L. Gubareva, Charlottesville, USA O. Haller, Freiburg, Germany F.G. Hayden, Charlottesville, VA, USA A. Holy´, Prague, Czech Republic J.W. Huggins, Fort Detrick, MD, USA C. Jonsson, Birmingham, AL, USA D. Kimberlin, Birmingham, Alabama, USA H. Kirchner, Lu¨beck, Germany B. Korba, Rockville, MD, USA J.J. Leary, Research Triangle Park, NC, USA G. Leroux-Roels, Gent, Belgium P. Ljungman, Stockholm, Sweden J.J. McSharry, Albany, NY, USA H. Mitsuya, Bethesda, MD, USA J. Neyts, Leuven, Belgium
¨ berg, Huddinge, Sweden B. O J. O’Connell, Pearl River, NY, USA A. Patick, San Diego, CA, USA C.-F. Perno, Rome, Italy R.B. Pollard, UC Davis, CA, USA R.F. Schinazi, Decatur, GA, USA J.A. Secrist III, Birmingham, AL, USA S. Shigeta, Fukushima, Japan R.W. Sidwell, Logan, UT, USA D.F. Smee, Logan, UT, USA S. Spruance, Salt Lake City, UT, USA C. Stafford-Gibbs, Foster City, CA, USA M. St. Clair, Research Triangle Park, NC, USA S. Vella, Rome, Italy A. Vlietinck, Antwerp, Belgium P. Wutzler, Jena, Germany N. Yamamoto, Tokyo, Japan F. Zoulim, Lyon, France
Author enquiries Authors can keep a track on the progress of their accepted article, and set up e-mail alerts informing them of changes to their manuscript’s status, by using the ‘‘Track a Paper’’ feature of Elsevier’s Author Gateway (http://www.authors. elsevier.com) Full details for the electronic submission of artwork can be obtained from http:/www.elsevier.com/locate/authorartwork/ Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication.
Antiviral Research has no page charges
Advertising information. Advertising orders and enquiries can be sent to: USA, Canada and South America: Mr Tino DeCarlo, The Advertising Department, Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710, USA; phone: (+1) (212) 633 3815; fax: (+1) (212) 633 3820; e-mail: [email protected]. Japan: The Advertising Department, Elsevier K.K., 4F Higashi-Azabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan; phone: (+81) (3) 5561 5037; fax: (+81) (3) 5561 5047; e-mail: [email protected]. Europe and ROW: Commercial Sales Department, Elsevier Ltd., The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK; phone: (+44) 1865 843016; fax: (+44) 1865 843976; e-mail: [email protected]
Publication information: Antiviral Research (ISSN 0166-3542). For 2005, volumes 65–68 are scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office nearest you or from this journal’s website (http://www.elsevier.com/locate/antiviral). Further information is available on this journal and other Elsevier products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of despatch. Orders, claims, and journal enquiries: please contact the Customer Service Department at the Regional Sales Office nearest you:
Tokyo: Elsevier, Customer Service Department, 4F Higashi-Azabu, 1-Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan; phone: (+81) (3) 5561 5037; fax: (+81) (3) 5561 5047; e-mail: [email protected]
USA mailing notice: Antiviral Research (ISSN 0166-3542) is published monthly by Elsevier B.V. (P.O. Box 211, 1000 AE Amsterdam, The Netherlands). Annual subscription price in the USA US$ 2143 (valid in North, Central and South America), including air speed delivery. Periodical postage rate paid at Jamaica, NY 11431. USA POSTMASTER: Send address changes to Antiviral Research, Publications Expediting Inc., 200 Meacham Ave, Elmont, NY 11003. AIRFREIGHT AND MAILING in the USA by Publications Expediting Inc., 200 Meacham Avenue, Elmont, NY 11003.
Singapore: Elsevier, Customer Service Department, 3 Killiney Road, #08-01 Winsland House I, Singapore 239519; phone: (+65) 63490222; fax: (+65) 67331510; e-mail: [email protected]
Printed in the United Kingdom
Orlando: Elsevier, Customer Service Department, 6277 Sea Harbor Drive, Orlando, FL 32887-4800, USA; phone: (+1) (877) 8397126 [toll free number for US customers], or (+1) (407) 3454020 [customers outside US]; fax: (+1) (407) 3631354; e-mail: [email protected] Amsterdam: Elsevier, Customer Service Department, PO Box 211, 1000 AE Amsterdam, The Netherlands; phone: (+31) (20) 4853757; fax: (+31) (20) 4853432; e-mail: [email protected]
* The paper used in this publication meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper) 1
ß 2005 Elsevier B.V. All rights reserved.
1 The paper in this publication meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper). *
0166-3542/2004/$20.00
||