- Email: [email protected]
INSIDE FRONT COVER-PUBLICATION INFORMATION
|
|
Aims and Scope NeuroToxicology specializes in publishing the best peer-reviewed original research papers dealing with the effects of toxic substances on the nervous system of humans and experimental animals of all ages. The Journal emphasizes papers dealing with the neurotoxic effects of environmentally significant chemical hazards, manufactured drugs and naturally occurring compounds. Papers dealing with the effects of neurotoxicants on other systems (e.g., reproductive, endocrine, immune) or processes (e.g., metabolic) are also welcome.
Contents continued
NeuroToxicology publishes papers in the following categories: Rapid Publication; Original Research Papers; Brief Communications; Reviews; Case Studies; Commentaries; Editorials; Letters to the Editor; Meeting Reports; Summaries and Abstracts of Selected Meetings, as well as Special Issues dedicated to a specific topic.
BRIEF COMMUNICATION
EDITOR-IN-CHIEF JOAN MARIE CRANMER, Professor of Pediatrics and Toxicology, Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital, 1120 Marshall – Room 304, Little Rock, Arkansas 72202-3591 USA. Tel.: +1-501364-2986; fax: +1-501-364-4978; E-mail: [email protected]
Aluminum Disrupts the Pro-Inflammatory Cytokine/Neurotrophin Balance in Primary Brain RotationMediated Aggregate Cultures: Possible Role in Neurodegeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . V.J. Johnson and R.P. Sharma (USA)
EDITORIAL ASSISTANTS Jacqueline P. O’Connor and Tina M. Daniel, Department of Pediatrics – #512, University of Arkansas for Medical Sciences, 1120 Marshall Street – Suite 304, Little Rock, Arkansas 72202 USA. Tel.: +1-501-364-3604; fax: +1-501-364-4978
TWENTIETH INTERNATIONAL NEUROTOXICOLOGY CONFERENCE
261
MEETING REPORT
EDITOR FOR REVIEWS Hugh A. Tilson, Assistant Laboratory Director for Multimedia Research, NHEERL (MD-51A), U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Tel.: +1-919-541-4607; fax: +1-919-541-1440; E-mail: [email protected]
20th International Neurotoxicology Conference: Emerging Issues in Neurotoxicology . . . . . . . . . . . . J.M. Cranmer (USA)
269
Sponsor/Co-sponsors/Contributors of Twentieth International Neurotoxicology Conference . . . . . .
271
Organizing Committee/Invited participants/Conference and Editorial Staff of Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
272
Program/Menu from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . .
273
Poster Abstracts from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . .
281
Abstracts from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . . . . . . .
286
INSTRUCTIONS TO AUTHORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
319
ASSOCIATE EDITORS Michael Aschner, Winston-Salem, NC, USA William D. Atchison, E. Lansing, MI, USA Gerald J. Audesirk, Denver, CO, USA Deborah Cory-Slechta, Rochester, NY, USA
Lucio G. Costa, Seattle, WA, USA Toma´s R. Guilarte, Baltimore, MD, USA Richard M. LoPachin, Bronx, NY, USA Toshio Narahashi, Chicago, IL, USA
John L. O’Donoghue, Rochester, NY, USA Kenneth R. Reuhl, Piscataway, NJ, USA Deborah C. Rice, Washington DC, USA William Slikker, Jr., Jefferson, AR, USA
EDITORIAL BOARD E Alleva, Rome, Italy SF Ali, Jefferson, AR, USA T Audesirk, Denver, CO, USA CA Bearer, Cleveland, OH, USA ML Billingsley, Hershey, PA, USA SC Bondy, Irvine, CA, USA JP Bressler, Baltimore, MD, USA TM Burbacher, Seattle, WA, USA KM Crofton, Research Triangle Park, NC, USA DA DiMonte, Sunnyvale, CA, USA DC Dorman, Research Triangle Park, NC, USA M Ehrich, Blacksburg, VA, USA LD Fechter Oklahoma City, OK, USA F Fonnum, Kjeller, Norway, USA
F Gerr, Atlanta, GA, USA GJ Harry, Research Triangle Park, NC, USA N Imura, Tokyo, Japan PR Kodavanti, Research Triangle Park, NC, USA SM Lasley, Peoria, IL, USA E Lock, Cheshire, United Kingdom HE Lowndes, Piscataway, NJ, USA VC Moser, Research Triangle Park, NC, USA MC Newland, Auburn, AL, USA S Padilla, Research Triangle Park, NC, USA MG Paule, Jefferson, AR, USA MA Philbert, Ann Arbor, MI, USA DE Ray, Nottingham, United Kingdom RJ Richardson, Ann Arbor, MI, USA
V Salgado, Research Triangle Park, NC, USA S Schantz, Urban, IL, USA R Seegal, Albany, NY, USA TJ Shafer, Research Triangle Park, NC, USA LP Sheets, Stilwell, KS, USA JB Suszkiw, Cincinnati, OH, USA E Tiffany-Castiglioni, College Station, TX, USA C Tohyama, Ibaraki, Japan M Anthony Verity, Los Angeles, CA, USA GR Wenger, Little Rock, AR, USA H Wiegand, Du¨sseldorf, Germany K Williams, Madison, WI, USA RA Yokel, Lexington, KY, USA
Abstracted/indexed in: Chemical Abstracts, Current Contents, Index Medicus, Excerpta Medica, Archives of Environmental Health, Biology Digest, BioSciences Information Service of Biological Abstracts (BIOSIS), the All-Union Institute of Scientific and Technical Information of the USSR, Medical Abstracts Service, Science Citation Index, Japanese Citation Index and various computer listings and indexes of the U.S. National Library of Medicine.
PII: S 0 1 6 1 - 8 1 3 X ( 0 3 ) 0 0 0 0 5 - 6 Publication information: NeuroToxicology1 (ISSN 0161-813X). For 2003, volume 24 is scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office nearest you or from this journal’s website (http://www.elsevier.com/locate/neuro). Further information is available on this journal and other Elsevier Science products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of dispatch.
This journal is part of ContentsDirect, the free alerting service which sends tables of contents by e-mail for Elsevier Science books and journals. You can register for ContentsDirect online at: http://contentsdirect.elsevier.com
To Obtain Back Issues of NeuroToxicology from Volume 1 (1979) to Volume 21 (2000): Contact NeuroToxicology, Back Issues Vol. 1–21 (1979–2000), P.O.Box 24865, Little Rock, AR 72221-4865. Tel.: +1-501-224-0813 or +1-501-364-2978; Fax: +1-501-224-1947 or +1-501-364-4978. USA mailing notice: NeuroToxicology1 (ISSN 0161-813X) is published bi-monthly (six issues per year) in February, April, June, August, October and December by Elsevier Science Inc. (P.O. Box 211, 1000 AE Amsterdam, The Netherlands). Annual subscription price in the USA US$319 (valid in North, Central and South America), including air speed delivery. Application to mail at periodical postage rate is pending at Jamaica, NY 11431. USA POSTMASTER: Send address changes to NeuroToxicology1, Publications Expediting Inc., 200 Meacham Ave, Elmont, NY 11003. AIRFREIGHT AND MAILING in the USA by Publications Expediting Inc., 200 Meacham Avenue, Elmont, NY 11003. Author enquiries For enquiries relating to the submission of articles (including electronic submission), the status of accepted articles, the preparation of electronic artwork, author Frequently Asked Questions and any other enquiries relating to Elsevier Science, please consult http:// authors.elsevier.com Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication. Cover photo: Morphology and immunochemical characterization of cultured oligodendrocyte lineage cells. (A) undifferentiated cultures; (B) cultures after 2 days of differentiation; (C) cultures after 6 days of differentiation. The cells were stained for the oligodendrocytic stage-specific markers A2B5, O4, GalC, and MBP, as well as astrocytic marker, GFAP. Percent of immunolabeled cells in the total population is shown in the left panel, and the data represent mean S.D. of at least three independent experiments. All experiments were performed in duplicate with at least 200 cells counted per condition. Representative micrographs are shown in the right panel. Undifferentiated cells exhibited a bipolar morphology and were strongly positive to A2B5. Cells after 2 days of differentiation showed a multi-branched morphology and were strongly positive to O4. Cells after 6 days of differentiation showed a complex network of cellular processes indicative of mature oligodendrocytes that were strongly positive to MBP. Scale bar = 60 mm. Taken from Deng and Poretz (2001a). For further details see article by Deng and Poretz et al., pp. 161–178 of this issue.
PII: S 0 1 6 1 - 8 1 3 X ( 0 3 ) 0 0 0 0 6 - 8
|
|
|
Aims and Scope NeuroToxicology specializes in publishing the best peer-reviewed original research papers dealing with the effects of toxic substances on the nervous system of humans and experimental animals of all ages. The Journal emphasizes papers dealing with the neurotoxic effects of environmentally significant chemical hazards, manufactured drugs and naturally occurring compounds. Papers dealing with the effects of neurotoxicants on other systems (e.g., reproductive, endocrine, immune) or processes (e.g., metabolic) are also welcome.
Contents continued
NeuroToxicology publishes papers in the following categories: Rapid Publication; Original Research Papers; Brief Communications; Reviews; Case Studies; Commentaries; Editorials; Letters to the Editor; Meeting Reports; Summaries and Abstracts of Selected Meetings, as well as Special Issues dedicated to a specific topic.
BRIEF COMMUNICATION
EDITOR-IN-CHIEF JOAN MARIE CRANMER, Professor of Pediatrics and Toxicology, Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital, 1120 Marshall – Room 304, Little Rock, Arkansas 72202-3591 USA. Tel.: +1-501364-2986; fax: +1-501-364-4978; E-mail: [email protected]
Aluminum Disrupts the Pro-Inflammatory Cytokine/Neurotrophin Balance in Primary Brain RotationMediated Aggregate Cultures: Possible Role in Neurodegeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . V.J. Johnson and R.P. Sharma (USA)
EDITORIAL ASSISTANTS Jacqueline P. O’Connor and Tina M. Daniel, Department of Pediatrics – #512, University of Arkansas for Medical Sciences, 1120 Marshall Street – Suite 304, Little Rock, Arkansas 72202 USA. Tel.: +1-501-364-3604; fax: +1-501-364-4978
TWENTIETH INTERNATIONAL NEUROTOXICOLOGY CONFERENCE
261
MEETING REPORT
EDITOR FOR REVIEWS Hugh A. Tilson, Assistant Laboratory Director for Multimedia Research, NHEERL (MD-51A), U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Tel.: +1-919-541-4607; fax: +1-919-541-1440; E-mail: [email protected]
20th International Neurotoxicology Conference: Emerging Issues in Neurotoxicology . . . . . . . . . . . . J.M. Cranmer (USA)
269
Sponsor/Co-sponsors/Contributors of Twentieth International Neurotoxicology Conference . . . . . .
271
Organizing Committee/Invited participants/Conference and Editorial Staff of Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
272
Program/Menu from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . .
273
Poster Abstracts from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . .
281
Abstracts from the Twentieth International Neurotoxicology Conference . . . . . . . . . . . . . . . . . . . . . .
286
INSTRUCTIONS TO AUTHORS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
319
ASSOCIATE EDITORS Michael Aschner, Winston-Salem, NC, USA William D. Atchison, E. Lansing, MI, USA Gerald J. Audesirk, Denver, CO, USA Deborah Cory-Slechta, Rochester, NY, USA
Lucio G. Costa, Seattle, WA, USA Toma´s R. Guilarte, Baltimore, MD, USA Richard M. LoPachin, Bronx, NY, USA Toshio Narahashi, Chicago, IL, USA
John L. O’Donoghue, Rochester, NY, USA Kenneth R. Reuhl, Piscataway, NJ, USA Deborah C. Rice, Washington DC, USA William Slikker, Jr., Jefferson, AR, USA
EDITORIAL BOARD E Alleva, Rome, Italy SF Ali, Jefferson, AR, USA T Audesirk, Denver, CO, USA CA Bearer, Cleveland, OH, USA ML Billingsley, Hershey, PA, USA SC Bondy, Irvine, CA, USA JP Bressler, Baltimore, MD, USA TM Burbacher, Seattle, WA, USA KM Crofton, Research Triangle Park, NC, USA DA DiMonte, Sunnyvale, CA, USA DC Dorman, Research Triangle Park, NC, USA M Ehrich, Blacksburg, VA, USA LD Fechter Oklahoma City, OK, USA F Fonnum, Kjeller, Norway, USA
F Gerr, Atlanta, GA, USA GJ Harry, Research Triangle Park, NC, USA N Imura, Tokyo, Japan PR Kodavanti, Research Triangle Park, NC, USA SM Lasley, Peoria, IL, USA E Lock, Cheshire, United Kingdom HE Lowndes, Piscataway, NJ, USA VC Moser, Research Triangle Park, NC, USA MC Newland, Auburn, AL, USA S Padilla, Research Triangle Park, NC, USA MG Paule, Jefferson, AR, USA MA Philbert, Ann Arbor, MI, USA DE Ray, Nottingham, United Kingdom RJ Richardson, Ann Arbor, MI, USA
V Salgado, Research Triangle Park, NC, USA S Schantz, Urban, IL, USA R Seegal, Albany, NY, USA TJ Shafer, Research Triangle Park, NC, USA LP Sheets, Stilwell, KS, USA JB Suszkiw, Cincinnati, OH, USA E Tiffany-Castiglioni, College Station, TX, USA C Tohyama, Ibaraki, Japan M Anthony Verity, Los Angeles, CA, USA GR Wenger, Little Rock, AR, USA H Wiegand, Du¨sseldorf, Germany K Williams, Madison, WI, USA RA Yokel, Lexington, KY, USA
Abstracted/indexed in: Chemical Abstracts, Current Contents, Index Medicus, Excerpta Medica, Archives of Environmental Health, Biology Digest, BioSciences Information Service of Biological Abstracts (BIOSIS), the All-Union Institute of Scientific and Technical Information of the USSR, Medical Abstracts Service, Science Citation Index, Japanese Citation Index and various computer listings and indexes of the U.S. National Library of Medicine.
PII: S 0 1 6 1 - 8 1 3 X ( 0 3 ) 0 0 0 0 5 - 6 Publication information: NeuroToxicology1 (ISSN 0161-813X). For 2003, volume 24 is scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office nearest you or from this journal’s website (http://www.elsevier.com/locate/neuro). Further information is available on this journal and other Elsevier Science products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of dispatch.
This journal is part of ContentsDirect, the free alerting service which sends tables of contents by e-mail for Elsevier Science books and journals. You can register for ContentsDirect online at: http://contentsdirect.elsevier.com
To Obtain Back Issues of NeuroToxicology from Volume 1 (1979) to Volume 21 (2000): Contact NeuroToxicology, Back Issues Vol. 1–21 (1979–2000), P.O.Box 24865, Little Rock, AR 72221-4865. Tel.: +1-501-224-0813 or +1-501-364-2978; Fax: +1-501-224-1947 or +1-501-364-4978. USA mailing notice: NeuroToxicology1 (ISSN 0161-813X) is published bi-monthly (six issues per year) in February, April, June, August, October and December by Elsevier Science Inc. (P.O. Box 211, 1000 AE Amsterdam, The Netherlands). Annual subscription price in the USA US$319 (valid in North, Central and South America), including air speed delivery. Application to mail at periodical postage rate is pending at Jamaica, NY 11431. USA POSTMASTER: Send address changes to NeuroToxicology1, Publications Expediting Inc., 200 Meacham Ave, Elmont, NY 11003. AIRFREIGHT AND MAILING in the USA by Publications Expediting Inc., 200 Meacham Avenue, Elmont, NY 11003. Author enquiries For enquiries relating to the submission of articles (including electronic submission), the status of accepted articles, the preparation of electronic artwork, author Frequently Asked Questions and any other enquiries relating to Elsevier Science, please consult http:// authors.elsevier.com Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication. Cover photo: Morphology and immunochemical characterization of cultured oligodendrocyte lineage cells. (A) undifferentiated cultures; (B) cultures after 2 days of differentiation; (C) cultures after 6 days of differentiation. The cells were stained for the oligodendrocytic stage-specific markers A2B5, O4, GalC, and MBP, as well as astrocytic marker, GFAP. Percent of immunolabeled cells in the total population is shown in the left panel, and the data represent mean S.D. of at least three independent experiments. All experiments were performed in duplicate with at least 200 cells counted per condition. Representative micrographs are shown in the right panel. Undifferentiated cells exhibited a bipolar morphology and were strongly positive to A2B5. Cells after 2 days of differentiation showed a multi-branched morphology and were strongly positive to O4. Cells after 6 days of differentiation showed a complex network of cellular processes indicative of mature oligodendrocytes that were strongly positive to MBP. Scale bar = 60 mm. Taken from Deng and Poretz (2001a). For further details see article by Deng and Poretz et al., pp. 161–178 of this issue.
PII: S 0 1 6 1 - 8 1 3 X ( 0 3 ) 0 0 0 0 6 - 8
|
|