Inside front cover(editorial board members)

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NEUROBIOLOGY OF AGING RESEARCH ON AGE-RELATED PHENOMENA, NEURODEGENERATION AND NEUROPATHOLOGY Founding Editor: Raymond T. Bartus

Editor-in-Chief PAUL D. COLEMAN Center for Aging and Developmental Biology The University of Rochester Medical Center, Box 645 601 Elmwood Avenue, Rochester, NY 14642 USA

SECTION EDITORS PHARMACOLOGY & ANIMAL MODELS

ALZHEIMER’S DISEASE & OTHER DEMENTIAS

Raymond T. Bartus: Ceregene, Inc., 9381 Judicial Drive, Suite 130, San Diego, CA 92121, USA

Ralph A. Nixon: Nathan Kline Institute for Psychiatric Research, New York University Medical Center, Dept. of Psychiatry, 140 Old Orangeburg Rd., Orangeburg, NY 10962 USA

STRUCTURE Harold Brody: Dept. of Anatomy & Cell Biology, State University of New York School of Medicine, Buffalo, NY 14214 USA Mark West: Department of Neurobiology & Anatomy, Building 234, University of Aarhus, 8000 Aarhus C, Denmark

BEHAVIOR Peter R. Rapp: Neurobiology of Aging Laboratories, Box 1639, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029 USA

Hiroshi Mori: Osada City University Medical School, Department of Neuroscience, 1-4-3 Asahimachi, Abenoku 545-8585, Japan

GENE EXPRESSION & NEUROGENETICS James I. Morgan: St. Jude’s Children’s Research Hospital, 332 North Lauderdale, Memphis, TN 38105-2794 USA

TRANSMITTER SYSTEMS Elaine K. Perry: Medical Research Council, Neurochemical Pathology Unit, Newcastle General Hospital, Westgate Road, Newcastle NE4 6BE United Kingdom

GENETICS & MODEL SYSTEMS

PHYSIOLOGY Caleb Finch: Andrus Gerontology Center, University of Southern California, University Park, Los Angeles, CA 90089 USA

Thomas E. Johnson: Institute for Behavioral Genetics University of Colorado, Boulder Boulder, CO 80309 USA

STRESS SIGNALING & NEUROPLASTICITY

CELL BIOLOGY & TROPHIC FACTORS Eugene M. Johnson, Jr.: Dept. of Pharmacology, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110 USA

Mark P. Mattson: National Institute on Aging Laboratory of Neuroscience GRC 4F01, 5600 Nathan Shock Drive Blvd. Baltimore, MD 21224, USA

EDITORIAL ADVISORY BOARD Marilyn S. Albert, Boston, MA Jesus Avila, Madrid, Spain Jocelyn Bachevalier, Houston, TX Heiko Braak, Frankfurt, Germany Carl W. Cotman, Irvine, CA C. DeCarli, Sacramento, CA D.W. Dickson, Jacksonville, FL James Eberwine, Philadelphia, PA Howard Eichenbaum, Boston, MA Dorothy Flood, West Chester, PA Fred H. Gage, La Jolla, CA Pierluigi Gambetti, Cleveland, OH Ezio Giacobini, Geneva, Switzerland William Greenough, Urbana, IL J. Hardy, Bethesda, MD Franz F. Hefti, San Diego, CA Karl Herrup, Cleveland, OH

Patrick R. Hof, New York, NY Bradley Hyman, Boston, MA Donald K. Ingram, Baltimore, MD Khalid Iqbal, Staten Island, NY J.A. Joseph, Boston, MA Zaven Khachaturian, Bethesda, MD Jeffrey Kordower, Chicago, IL Philip W. Landfield, Lexington, KY W. R. Markesbery, Lexington, KY Michael McKinney, Jacksonville, FL John Morrison, New York, NY Elliott Mufson, Chicago, IL James F. Nelson, San Antonio, TX G.M. Pasinetti, New York, NY D. Peterson, North Chicago, IL Jay W. Pettegrew, Pittsburgh, PA Creighton H. Phelps, Bethesda, MD

H. Potter, Tampa, FL R. Quirion, Quebec, Canada Joseph Rogers, Sun City, AZ Paul R. Sanberg, Tampa, FL Robert M. Sapolsky, Stanford, CA Michael L. Shelanski, New York, NY J. R. Slemmon, King of Prussia, PA M.A. Smith, Cleveland, OH A. David Smith, Oxford, United Kingdom M. Sofroniew, Los Angeles, CA Joseph Springer, Lexington, KY D. Swaab, Amsterdam, The Netherlands Leon Thal, San Diego, CA L. de Toledo-Morrell, Chicago, IL John Q. Trojanowski, Philadelphia, PA Steven Younkin, Jacksonville, FL Berislav Zlokovic, Rochester, NY

Advertising information: Advertising orders and enquiries can be sent to: USA, Canada and South America: Mr Tino DeCarlo, The Advertising Department, Elsevier Science Inc., 360 Park Avenue South, New York, NY 10010-1710, USA; phone: (1) (212) 633 3815; fax: (1) (212) 633 3820; e-mail: [email protected]. Japan: The Advertising Department, Elsevier Science K.K., 9-15 Higashi-Azabu 1-chome, Minato-ku, Tokyo 106-0044, Japan; phone: (81) (3) 5561 5033; fax (81) (3) 5561 5047. Europe and ROW: Commercial Sales Department, Elsevier Science Ltd., The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK; phone: (44) 1865 843016; fax: (44) 1865 843976; e-mail: [email protected] Publication information: Neurobiology of Aging (ISSN 0197-4580). For 2003, Volume 24 is scheduled for publication. Subscription prices are available upon request from the Publisher or from the Regional Sales Office nearest you or from this journal’s website (http://www.elsevier.com/locate/neuaging). Further information is available on this journal and other Elsevier Science products through Elsevier’s website: (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of dispatch.

PII: S0197-4580(03)00016-2

Aims and Scope Neurobiology of Aging will publish the results of studies in behavior, biochemistry, cell biology, endocrinology, molecular biology, morphology, neurology, neuropathology, pharmacology, physiology and protein chemistry in which the primary emphasis involves mechanisms of nervous system changes with age or diseases associated with age. Reviews and theoretical articles will be published, usually accompanied

by open peer commentary. Letters to the Editor and brief communications are also acceptable. Brief reports of highly time-sensitive material may be treated as rapid communications in which case editorial review will be completed within six weeks and publication scheduled for the next available issue. Articles will be published in English.

The accepted abbreviation for Neurobiology of Aging for bibliographic citation is Neurobiol Aging.

INSTRUCTIONS TO AUTHORS All manuscripts should be sent to the Editor-in-Chief for review and processing. Authors are referred to the following published editorial policy statements: Coleman, P. D. How old is old? Neurobiol. Aging 10:115;1989. Coleman, P. D.; Finch, C. E.; Joseph, J. The need for multiple time points in aging studies. Neurobiol. Aging 11:1–2;1990. Finch, C. E. Middle-age: An evolving frontier in gerontology. Neurobiol. Aging 12:1–2;1991. West, M. J. New stereological methods for counting neurons. Neurobiol. Aging 14:275-285;1993. West, M. J.; Coleman, P. D. How to count. Neurobiol. Aging 17:503;1996.

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