Abstracts
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EP000692 Blood glucose profile of patients with essential hypertension in China
EP000703 Interaction of body mass index and alcohol consumption with hypertension risk in Han Chinese
N.L. SUN, H.Y. WANG, Y. XI Peking University People's Hospital, China
MINGLIANG GUa, MINGPING LIb, WENQUAN NIUc,d Department of Genetics, Beijing Institute of Genomics, Chinese Academy of Science, China b Health Bureau of the Shandong Shengli Oil Field, China c State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, and Shanghai Institute of Hypertension, China d Sino-French Research Center for Life Science and Genomics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China
Objective: To investigate the blood glucose metabolitic profile of patients with essential hypertension in Chinese five central cities, and to provide scientific evidence for a further full-scale intervention of risk factors. Design and methods: In this cross-sectional epidemiologic research, patients with essential hypertension and without known diabetes mellitus (DM), who came to cardiologic out-patient clinics in 5 Chinese central cities, were invited to answer questionnaires on glycemic metabolic status and undertook blood glucose tests including FBG and OGTT. Results: Among recruited hypertensive patients, a total of 5003, fasting blood sugar (FBS) of 1373 (27.4%) patients were ≥5.6 mmol/L. Further, the results of FBS and oral glucose tolerance test (OGTT) 2 hour blood glucose were obtained from 1421 patients. Among them, 326 patients (22.9%) were diagnosed as diabetes mellitus and glycemic metabolism disturbance were found in 915 patients (64.4%). Hypertensive patients who were concomitant with diabetes mellitus had higher levels of systolic pressure, waist circumference waist-to-hip ratio and plasma triglyceride than the others. Conclusions: Among patients with essential hypertension, there was a high incidence of impaired glucose tolerance inversely with a very low rate of diagnosis. Glycemic metabolic status should be paid more attention in hypertension patients, and an early OGTT test was strongly suggested, which were very important for welltimed diagnosis and treatment of glycemic metabolic disorder and for interventing effectively to decrease the incidence of cardiovascular diseases. doi:10.1016/j.ijcard.2009.09.202 EP000693 Hypertension in the elderly BESMA BEN DHAOU, FATMA BOUSSEMA, FATIMA JAZIRI, SONIA KETARI, OUAHIDA CHERIF, ROKBANI LILIA Habib Thameur Hospital, Tunisia Hypertension is one of the most significant risk factors for cerebrovascular and heart diseases in elderly population whose size, in our country, continues to increase. Our study aims were to determine the epidemiological characteristics of elderly hypertensive patients admitted to the internal medicine department, to study the different cardiovascular factors, to evaluate the benefits of treating hypertension and to discuss the different therapeutic attitude. We studied 57 hypertensive patients, 65 years or older, admitted to the internal medicine department during year 2002. After collection and analysis of facts, we noticed that the prevalence of hypertension in admitted elderly patients was about 46%, there is a feminine predominance, the hypertension increases the hospitalisation term, formed an association with diabetes mellitus. We noticed also that the hypertension was unknown in 9% of cases, 50% of elderly hypertensive patients have developed visceral complications and 65% of them had evolutive cardiovascular complications such as renal failure, hypertensive cardiopathy and cerebrovascular diseases. In treatment, we noticed that only 25% of patients have controlled hypertension with ambulatory treatment and in 50% of cases we have to change the treatment quantitatively and/or qualitatively. The hypertension in elderly was an important risk factor of morbid-mortality. doi:10.1016/j.ijcard.2009.09.203
a
Obesity and excessive drinking are major public health epidemics. As evidenced, obesity as surrogated by body mass index (BMI) and excessive drinking are strongly associated with blood pressure (BP) variation. The aim of the present study was to explore the association of BMI and alcohol consumption along or in combination with hypertension risk in a large-scale hypertension survey (2003–2004) in Shandong, China. Demographics, medical history, and lifestyles were collected at the time of enrollment. The relationship between systolic/diastolic BP and BMI (as categorical variable) was J-shaped in both genders after controlling for age, with the lowest BP levels observed among study participants with a BMI of 18.0–19.9 kg/m2 in men and women. Also the lowest BP levels were observed in moderate drinkers in both genders. After adjusting for confounders, a graded increase of hypertension risk was found within each drinking category with the increase of BMI. For example, as for male heavy drinkers with a BMI of 15.0–17.9, 18.0–19.9, 20.0–21.9, 22.0–23.9, 24.0–25.9, 26.0–29.9 and 30.0 or more kg/m2, the adjusted relative risks (95%CI) for hypertension were 3.75 (1.28, 6.46), 2.83 (1.83, 4.39), 2.44 (1.33, 4.46), 3.39 (2.24, 5.13), 4.61 (3.07, 6.92), 6.67 (4.46, 9.98), and 14.12 (8.76, 22.76), respectively. Taken together, our study provides evidence for the interactive effect of BMI and alcohol consumption on BP variation and hypertension risk in Chinese workers. Future perspective studies are warranted to confirm or refute these findings. doi:10.1016/j.ijcard.2009.09.204 EP000709 Investigation on phychological actuality of the elderly patients with hypertension after the megaseism in Wenchuan XUECHUN SUN, XIAOFANG ZHOU, YUJIAO WANG Sichuan Provincial Hospital, China To understand the mental health of the surviving elderly hypertensive patients after one year of the megaseism in Wenchuan of Sichuan Province. Adopting stratified cluster random sampling method to carry out sampling investigation on elderly hypertensive patients who are 60 and more than 60 years old, living in the temporary shield district after the megaseism; adopting self-rating anxiety scale (SAS) and self-rating depression scale (SDS) for Assessment of anxiety and depression. One year after the megaseism, the anxiety score of the elderly hypertensive patients living in the temporary shield district is higher than that of the population without hypertension who lived at the same place (24.94% and 18.07). Moreover, the depression score is higher than that of the population without hypertension who lived at the same place (33.50% and 18.26). Female patients' score is higher than that of the male patients. The incidents of anxiety and depression in elderly patients with hypertension in earthquake-stricken areas is higher, especially for the female patients. When doctors treat the diseases, they also should attach great importance to the patients' mental health. doi:10.1016/j.ijcard.2009.09.205