- Email: [email protected]
INTRADUCTAL CARCINOMA OF THE SUBMANDIBULAR GLAND
ABSTRACTS
e20
INTRADUCTAL CARCINOMA OF THE SUBMANDIBULAR GLAND. BRUNO AUGUSTO LINHARES ALMEIDA MARIZ, THAYNA MELO DE LIMA MORAIS, JACKS JORGE JUNIOR, OSLEI PAES DE ALMEIDA, MARIA GORETTI FREIRE DE CARVALHO and, CIRO DANTAS SOARES Intraductal carcinoma, a low-grade malignancy of the salivary glands, is an exceeding rare malignant tumor. With about 40 cases reported, it is more common in the parotid gland. We report 1 case of intraductal carcinoma arising in the submandibular gland of a 24-year-old female patient. Microscopically, the tumor presented with a macrocystic architecture lined by intraductal malignant cell proliferation resembling atypical ductal hyperplasia or in situ ductal carcinoma of the breast. In some areas, the tumor showed typical features of conventional salivary duct carcinoma with highgrade solid nests, comedonecrosis, and apocrine differentiation, without evidence of invasion. The tumor cells were positive for AE1/AE3 antibody, cytokeratin (CK) 7, and epithelial membrane antigen (EMA). Basal and myoepithelial cells were evident surrounding the ductal structures, and were positive for a-smooth muscle actin (a-SMA), calponin, and p63. Focal positivity for S100 and mammaglobin was also observed. The patient underwent surgical treatment and has no evidence of the disease after 41 months of follow-up examination.
SCHIMMELPENNING SYNDROME: A CASE REPORT. ROBERTA RAYRA MARTINS CHAVES, AECIO ABNER CAMPOS PINTOJR, JOANNA FARIAS DA CUNHA, FELIPE BAIRES CAMPOS, RICARDO SANTIAGO GOMEZ, RICARDO ALVES DE MESQUITA and, WAGNER HENRIQUES DE CASTRO A 6-year-old girl with a history of epilepsy was referred due to a mandibular lesion. Physical examination revealed the presence of sebaceous nevi involving skin of the face and neck. Intraoral exam revealed an asymptomatic swelling, firm to palpation, covered by mucosa of normal color, in the anterior mandible. The cone beam tomography revealed a presence of 3 well-defined mixed images, associated with impacted teeth 81, 82, and 42. The lesions were surgically excised and the histologic diagnosis was of adenomatoid odontogenic tumors (AOTs). Considering the multiple intraosseous neoplasms and the neurologic and epidermal affections, the diagnosis of Schimmelpenning syndrome was established. After 4 years, a lesion was found in the anterior region of the maxilla with clinical and imaging aspects similar to those of the previous lesions. After enucleation, the histologic analysis again indicated AOT. In 1 year of follow-up evaluation, no signs of recurrence were found. Support: FAPEMIG.
HYALURONIC ACID DERMAL FILLERS IN THE MANAGEMENT OF RECURRENT ANGULAR CHEILITIS: A CASE REPORT. MARIO PEREZ SAYANS, PILAR GANDARA VILA, ABEL GARCIA, ANDRES BLANCO CARRION, SERGIO e PINEIRO DONIS, CINTIA CHAMORRO PETRONACCI and, ALEJANDRO I LORENZO POUSO Angular cheilitis (AC) is a common oral pathology characterized by erythema, fissures, and crusting at 1 or both labial commissures. Pain and itchiness typically accompany these lesions. The objective is to report conservative treatment based
OOOO January 2020 on the use of dermal fillers for a case of recurrent AC. This is a case report of an 80-year-old patient with a history of recurrent AC that was not resolved with a conventional approach. The patient presented deep and irregular Y-shaped wrinkles by the union of the nasolabial fold with the labial commissure, which is why we chose to perform a mesh lift injection from the mentolabial sulcus with a 28-gauge needle. The hyaluronic acid worked as a suspender to maintain the elevated position of the perioral tissues. This case illustrates the potential of nonsurgical facial aesthetics (NSFAs), aside from achieving aesthetic goals, for treating this common pathology among elderly.
LABIOFACIAL NECROTIZING FASCIITIS: A CASE REPORT. MARIA LETICIA DE ALMEIDA ^ LANCA, ¸ VALFRIDO ANTONIO PEREIRA FILHO, ANDREIA BUFALINO, CAMILA DE OLIVEIRA BARBEIRO, JOSE CLEVEILTON DOS SANTOS, AUDREY FOSTER LEFORT ROCH and, CLAUDIA MARIA NAVARRO Necrotizing fasciitis (FN) is a rapidly progressive infection of the deeper tissues with destruction of muscle fascia and a high mortality rate. It is extremely rare and usually it is related to immunosuppression or other systemic debilitating conditions. A 26-year-old white male presented with upper lip edema, with phlogistic signs and infiltration through the infraorbital space along with the presence of tissue necrosis. According to the report, the condition was marked by rapid progression, and the initial manifestation was an acnelike lesion. The treatment was done immediately by incision, drainage, debridement, and installation of drains. The muscle fascia was necrotic, gray, and there was an absence of resistance. Laboratory tests were performed and the microbiologic culture was positive for Staphylococcus aureus. Endovenous antibiotic therapy was administered and the wound was irrigated daily. Healing was completed within a month. NF is a rare infection that must be diagnosed and treated aggressively to avoid tissue loss and to decrease the mortality rate.
PLASMA CELL CHEILITIS SUCCESSFULLY TREATED WITH TOPICAL CORTICOSTEROID AND CRYOTHERAPY. CAMILA DE OLIVEIRA BARBEIRO, DARCY FERNANDES, HEITOR ALBERGONI DA SILVEIRA, ROSE MARA ORTEGA, LUCIANA YAMAMOTO ALMEIDA, JORGE ESQUICHE LEON and, ANDREIA BUFALINO Plasma cell cheilitis (PCC) is an unusual benign plasma cell proliferative disease of an unknown etiology that clinically presents as erythematous-violaceous plaques, ulcerations, or eruptions often affecting the lower lip. PCC is known to respond poorly to corticosteroid treatment. A 43-year-old male presented with multiple painful hemorrhagic crusts on the lower lip that had developed over 1 month. An incisional biopsy was performed and microscopy showed a bandlike inflammatory cell infiltration composed mainly of plasma cells in the connective tissue. Immunohistochemistry confirmed a reactive nature of plasma cells. Thus, the diagnosis of PCC was established. Initially, the patient was treated with topical corticosteroids over 1 month, but had a relapse 3 months after complete remission. Then, we proposed the use of topical corticosteroids with cryotherapy. No recurrence was observed after 8 months of followup. In conclusion, cryotherapy associated with topical
e20
INTRADUCTAL CARCINOMA OF THE SUBMANDIBULAR GLAND. BRUNO AUGUSTO LINHARES ALMEIDA MARIZ, THAYNA MELO DE LIMA MORAIS, JACKS JORGE JUNIOR, OSLEI PAES DE ALMEIDA, MARIA GORETTI FREIRE DE CARVALHO and, CIRO DANTAS SOARES Intraductal carcinoma, a low-grade malignancy of the salivary glands, is an exceeding rare malignant tumor. With about 40 cases reported, it is more common in the parotid gland. We report 1 case of intraductal carcinoma arising in the submandibular gland of a 24-year-old female patient. Microscopically, the tumor presented with a macrocystic architecture lined by intraductal malignant cell proliferation resembling atypical ductal hyperplasia or in situ ductal carcinoma of the breast. In some areas, the tumor showed typical features of conventional salivary duct carcinoma with highgrade solid nests, comedonecrosis, and apocrine differentiation, without evidence of invasion. The tumor cells were positive for AE1/AE3 antibody, cytokeratin (CK) 7, and epithelial membrane antigen (EMA). Basal and myoepithelial cells were evident surrounding the ductal structures, and were positive for a-smooth muscle actin (a-SMA), calponin, and p63. Focal positivity for S100 and mammaglobin was also observed. The patient underwent surgical treatment and has no evidence of the disease after 41 months of follow-up examination.
SCHIMMELPENNING SYNDROME: A CASE REPORT. ROBERTA RAYRA MARTINS CHAVES, AECIO ABNER CAMPOS PINTOJR, JOANNA FARIAS DA CUNHA, FELIPE BAIRES CAMPOS, RICARDO SANTIAGO GOMEZ, RICARDO ALVES DE MESQUITA and, WAGNER HENRIQUES DE CASTRO A 6-year-old girl with a history of epilepsy was referred due to a mandibular lesion. Physical examination revealed the presence of sebaceous nevi involving skin of the face and neck. Intraoral exam revealed an asymptomatic swelling, firm to palpation, covered by mucosa of normal color, in the anterior mandible. The cone beam tomography revealed a presence of 3 well-defined mixed images, associated with impacted teeth 81, 82, and 42. The lesions were surgically excised and the histologic diagnosis was of adenomatoid odontogenic tumors (AOTs). Considering the multiple intraosseous neoplasms and the neurologic and epidermal affections, the diagnosis of Schimmelpenning syndrome was established. After 4 years, a lesion was found in the anterior region of the maxilla with clinical and imaging aspects similar to those of the previous lesions. After enucleation, the histologic analysis again indicated AOT. In 1 year of follow-up evaluation, no signs of recurrence were found. Support: FAPEMIG.
HYALURONIC ACID DERMAL FILLERS IN THE MANAGEMENT OF RECURRENT ANGULAR CHEILITIS: A CASE REPORT. MARIO PEREZ SAYANS, PILAR GANDARA VILA, ABEL GARCIA, ANDRES BLANCO CARRION, SERGIO e PINEIRO DONIS, CINTIA CHAMORRO PETRONACCI and, ALEJANDRO I LORENZO POUSO Angular cheilitis (AC) is a common oral pathology characterized by erythema, fissures, and crusting at 1 or both labial commissures. Pain and itchiness typically accompany these lesions. The objective is to report conservative treatment based
OOOO January 2020 on the use of dermal fillers for a case of recurrent AC. This is a case report of an 80-year-old patient with a history of recurrent AC that was not resolved with a conventional approach. The patient presented deep and irregular Y-shaped wrinkles by the union of the nasolabial fold with the labial commissure, which is why we chose to perform a mesh lift injection from the mentolabial sulcus with a 28-gauge needle. The hyaluronic acid worked as a suspender to maintain the elevated position of the perioral tissues. This case illustrates the potential of nonsurgical facial aesthetics (NSFAs), aside from achieving aesthetic goals, for treating this common pathology among elderly.
LABIOFACIAL NECROTIZING FASCIITIS: A CASE REPORT. MARIA LETICIA DE ALMEIDA ^ LANCA, ¸ VALFRIDO ANTONIO PEREIRA FILHO, ANDREIA BUFALINO, CAMILA DE OLIVEIRA BARBEIRO, JOSE CLEVEILTON DOS SANTOS, AUDREY FOSTER LEFORT ROCH and, CLAUDIA MARIA NAVARRO Necrotizing fasciitis (FN) is a rapidly progressive infection of the deeper tissues with destruction of muscle fascia and a high mortality rate. It is extremely rare and usually it is related to immunosuppression or other systemic debilitating conditions. A 26-year-old white male presented with upper lip edema, with phlogistic signs and infiltration through the infraorbital space along with the presence of tissue necrosis. According to the report, the condition was marked by rapid progression, and the initial manifestation was an acnelike lesion. The treatment was done immediately by incision, drainage, debridement, and installation of drains. The muscle fascia was necrotic, gray, and there was an absence of resistance. Laboratory tests were performed and the microbiologic culture was positive for Staphylococcus aureus. Endovenous antibiotic therapy was administered and the wound was irrigated daily. Healing was completed within a month. NF is a rare infection that must be diagnosed and treated aggressively to avoid tissue loss and to decrease the mortality rate.
PLASMA CELL CHEILITIS SUCCESSFULLY TREATED WITH TOPICAL CORTICOSTEROID AND CRYOTHERAPY. CAMILA DE OLIVEIRA BARBEIRO, DARCY FERNANDES, HEITOR ALBERGONI DA SILVEIRA, ROSE MARA ORTEGA, LUCIANA YAMAMOTO ALMEIDA, JORGE ESQUICHE LEON and, ANDREIA BUFALINO Plasma cell cheilitis (PCC) is an unusual benign plasma cell proliferative disease of an unknown etiology that clinically presents as erythematous-violaceous plaques, ulcerations, or eruptions often affecting the lower lip. PCC is known to respond poorly to corticosteroid treatment. A 43-year-old male presented with multiple painful hemorrhagic crusts on the lower lip that had developed over 1 month. An incisional biopsy was performed and microscopy showed a bandlike inflammatory cell infiltration composed mainly of plasma cells in the connective tissue. Immunohistochemistry confirmed a reactive nature of plasma cells. Thus, the diagnosis of PCC was established. Initially, the patient was treated with topical corticosteroids over 1 month, but had a relapse 3 months after complete remission. Then, we proposed the use of topical corticosteroids with cryotherapy. No recurrence was observed after 8 months of followup. In conclusion, cryotherapy associated with topical