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Investigation of Rh-antigen content of placenta
828
Selected
abstracts
Rothe,
J.: On the Contradiction Between Psycho-Prophylaxis and Relaxation, p. 1513. Tschakmakoff, P., and Reitscheff, R.: Primary Exocervical Pregnancy, p. 1520. Gill&en and Wagner-Koch: Clinically Controlled Result of the Pregnancy Test With Immature Rats Plus Its Response to Various Drugs, p. 1489. The hyperemia test with mature female rats showed no false-positives or false-negatives in 200 controlled cases. Except in the case of Priscoline, vasodilator drugs taken by the patients did not produce sufficient ovarian hyperemia in the animals to invalidate the readings. Walter F. Tauhcr Bar.4
and Gy&gy&sy: Investigation of Rh. Antigen Content of Placenta, p. 1507. With use of an absorption method, it was attempted to demonstrate Rh-antigens in the placenta of 14 Rh-positive and 1 Rh-negative fetus and in the amniotic fluid of 14 Rh-positive and 4 Rh-negative fetuses. The results tend to show that Rh antigen is not limited to the erythrocytes of the fetus, but is also present in the placental epithelium and perhaps the amniotic fluid. It appears that fetal tissues, other than blood cells, can be a source of sensitization in the mother although their antigenicity is lower and produces only a “booster” effect and not a primary immunization. Walter F. Tauber 1959. W., and &uch, H.: The Importance of Pre-eclampsia and Its Relation to Eclampsia, p. 1569. “Kyank, H., Scheele, V., and Trommer, R.: Toxemia of Pregnancy in the Department of Gynecology of the University of Leipzig From 1952 to 1956, Part lMothers With Toxemia, p. 1578. *Scheele, V., Kyank, H., and Trommer, R.: Toxemia of Pregnancy in the Department of Gynecology of the University of Leipzig From 1952 to 1956, Part 2Children of Mothers With Toxemia, p. 1591. Heyne, W.: Clinical Contribution on Strength of Fetal Membranes, p. 1602. Slunsky, R.: Changes in Platelet Count in Rabbits After Amniotic Fluid Infusion, p. Oct.
3,
*Bahm,
1604.
Am.
Biihm
October, 1960 J. Obst. & Gynec.
and Bruch: Importance of Pre-eclampsia and Its Relation to Eclampsia, p. 1569. In the years 1956 and 1957 there were 5,610 deliveries in the Nurenberg municipal hospitals, with 91 cases of pre-eclampsia (1.63 per cent). All patients with toxemia received vigorous therapy with sedatives and hypotensive drugs. None developed eclampsia. Ifowever, there were 7 eclamptic patients, 6 of whom were admitted after their first seizure. The other one had her first convulsion within a few minutes of arriving at the hospital. This leads to the conclusion that adequate treatment of pre-eclampsia can always prevent eclampsia. No specific neuropsychiatric changes were observed, although there was a high incidence of “dullness.” However, it was noted that the toxemia group was largely derived from “lower socioeconomic strata.” Seventy-nine per cent of pre-eclamptic, and 71 per cent of cclamptic patients recovered completely in 2 weeks post partum. In all other patients a history of pre-existing vascular and renal disease could be established. The authors feel that better diagnostic facilities than were available to them would have showed some patients with underlying kidney disease also in their “recovered” group. Thirty patients went into labor before the thirty-sixth week; 57 in the tenth lunar month; in 2 labor was induced because of postmaturity. Dyskinesia occurred 9 times, including one cesarean section for this as partial indication in a patient in whom labor was induced for refractory pre-eclarnpsia. There was a. total of 6 cesarean sections (6.2 per cent compared to over-all 2.06 per cent). However, in only 2 of these was the indication unrelated to toxemia. The incidence of hemorrhage was not higher than for nontoxemic mothers. There were no maternal deaths in the pre-eclampsia group, but one in the cclampsia series. A4anuaI removal of the placenta was found necessary in 7.68 per cent (1.85 per cent in all deliveries). Exploration for placental fragments was required in 13.9 per cent (2.51 per cent over-all). This is thought to be associated with the histologic and circulatory changes in the placenta in toxemia. Fetal mortality in the series was 18.55 per rent (4.84 per cent for all deliveries). This divides into 5.8 per cent for mature (versus 1.53 per cent) and 48.27 per cent for premature
Selected
abstracts
Rothe,
J.: On the Contradiction Between Psycho-Prophylaxis and Relaxation, p. 1513. Tschakmakoff, P., and Reitscheff, R.: Primary Exocervical Pregnancy, p. 1520. Gill&en and Wagner-Koch: Clinically Controlled Result of the Pregnancy Test With Immature Rats Plus Its Response to Various Drugs, p. 1489. The hyperemia test with mature female rats showed no false-positives or false-negatives in 200 controlled cases. Except in the case of Priscoline, vasodilator drugs taken by the patients did not produce sufficient ovarian hyperemia in the animals to invalidate the readings. Walter F. Tauhcr Bar.4
and Gy&gy&sy: Investigation of Rh. Antigen Content of Placenta, p. 1507. With use of an absorption method, it was attempted to demonstrate Rh-antigens in the placenta of 14 Rh-positive and 1 Rh-negative fetus and in the amniotic fluid of 14 Rh-positive and 4 Rh-negative fetuses. The results tend to show that Rh antigen is not limited to the erythrocytes of the fetus, but is also present in the placental epithelium and perhaps the amniotic fluid. It appears that fetal tissues, other than blood cells, can be a source of sensitization in the mother although their antigenicity is lower and produces only a “booster” effect and not a primary immunization. Walter F. Tauber 1959. W., and &uch, H.: The Importance of Pre-eclampsia and Its Relation to Eclampsia, p. 1569. “Kyank, H., Scheele, V., and Trommer, R.: Toxemia of Pregnancy in the Department of Gynecology of the University of Leipzig From 1952 to 1956, Part lMothers With Toxemia, p. 1578. *Scheele, V., Kyank, H., and Trommer, R.: Toxemia of Pregnancy in the Department of Gynecology of the University of Leipzig From 1952 to 1956, Part 2Children of Mothers With Toxemia, p. 1591. Heyne, W.: Clinical Contribution on Strength of Fetal Membranes, p. 1602. Slunsky, R.: Changes in Platelet Count in Rabbits After Amniotic Fluid Infusion, p. Oct.
3,
*Bahm,
1604.
Am.
Biihm
October, 1960 J. Obst. & Gynec.
and Bruch: Importance of Pre-eclampsia and Its Relation to Eclampsia, p. 1569. In the years 1956 and 1957 there were 5,610 deliveries in the Nurenberg municipal hospitals, with 91 cases of pre-eclampsia (1.63 per cent). All patients with toxemia received vigorous therapy with sedatives and hypotensive drugs. None developed eclampsia. Ifowever, there were 7 eclamptic patients, 6 of whom were admitted after their first seizure. The other one had her first convulsion within a few minutes of arriving at the hospital. This leads to the conclusion that adequate treatment of pre-eclampsia can always prevent eclampsia. No specific neuropsychiatric changes were observed, although there was a high incidence of “dullness.” However, it was noted that the toxemia group was largely derived from “lower socioeconomic strata.” Seventy-nine per cent of pre-eclamptic, and 71 per cent of cclamptic patients recovered completely in 2 weeks post partum. In all other patients a history of pre-existing vascular and renal disease could be established. The authors feel that better diagnostic facilities than were available to them would have showed some patients with underlying kidney disease also in their “recovered” group. Thirty patients went into labor before the thirty-sixth week; 57 in the tenth lunar month; in 2 labor was induced because of postmaturity. Dyskinesia occurred 9 times, including one cesarean section for this as partial indication in a patient in whom labor was induced for refractory pre-eclarnpsia. There was a. total of 6 cesarean sections (6.2 per cent compared to over-all 2.06 per cent). However, in only 2 of these was the indication unrelated to toxemia. The incidence of hemorrhage was not higher than for nontoxemic mothers. There were no maternal deaths in the pre-eclampsia group, but one in the cclampsia series. A4anuaI removal of the placenta was found necessary in 7.68 per cent (1.85 per cent in all deliveries). Exploration for placental fragments was required in 13.9 per cent (2.51 per cent over-all). This is thought to be associated with the histologic and circulatory changes in the placenta in toxemia. Fetal mortality in the series was 18.55 per rent (4.84 per cent for all deliveries). This divides into 5.8 per cent for mature (versus 1.53 per cent) and 48.27 per cent for premature