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Keyword Index (vol 36)
Experimental Gerontology 36 (2001) 1825±1829
Experimental Gerontology 36 (2001) 1825±1829
Keyword Index Acetylcholine, 99 Activin A, 1403 Adaptation, 1727 Adaptive cellular response, 1539 Advanced glycation end-products, 1527 Advanced glycosylation endoproducts, 869 A¯atoxin B1, 255 Age, 739 Age-associated disabilities, 3 Age-dependent mortality, 687 Age-independent mortality, 687 Ageing, 125, 159, 245, 475, 497, 583, 641, 947, 1221, 1375, 1503, 1699, 1739 Ageing model, 899 Ageing research, 383, 935 Aging, 3, 99, 111, 177, 193, 209, 221, 255, 267, 311, 327, 341, 441, 507, 519, 547, 675, 695, 813, 869, 957, 969, 995, 1063, 1075, 1083, 1101, 1137, 1155, 1189, 1251, 1361, 1387, 1403, 1413, 1425, 1551, 1565, 1639, 1673, 1687, 1713 Aging and in¯ammation, 619 Aging biomarkers, 1277 Aging mutants, 1609 Aging of organisms, 651 Aging-related mortality, 845 Alloimmune response, 1761 Aluminium, 231 alpha-2-Macroglobulin, 487 Alu repeats, 1063 Alzheimer's Disease (AD), 1251 Alzheimer's disease, 171, 487, 559, 1179, 1551 Amantadine treatment, 1761 Amylase, 141 Animal, 1727 Antagonist co-activation, 1687 Antagonistic pleiotropy, 607, 1619 Antigen presenting cells, 519 Antioxidant, 327, 441 Antioxidants, 209, 1713 Aorta, 111 Apis mellifera, 695 Apoptosis, 311, 969, 995, 1251, 1327 Arachidonic acid, 65 Aspartate, 267 Astrocyte, 231
Atherosclerosis, 969, 1413, 1425 ATP, 99 Atropine-resistant contraction, 99 Autoimmunity, 519 Autophagy lysosomal proteolysis, 497 Bacterial-feeding nematode, 431 Basic gerontological research, 403 B cells, 537, 1761 Beverton, 765 Biodemography, 419 Bioimpedance, 159, 1699 Biological aging, 1539 Biological gerontology, 1221 Biomedical gerontology, 1221, 1581 Bird longevity, 599 Birds, 641, 845, 869 Bladder smooth muscle, 99 Blanding's turtle, 813 Blindness, 1083 Body composition, 159, 1699 Body mass index, 363 Box turtle, 829 Brain, 1387, 1713 Brain and aging, 859 Brain size, 845 Bristlecone pine, 675 5-Bromodeoxyuridine, 465 Caenorhabditis elegans, 431 Calcium regulatory proteins, 1539 Calorie restriction, 1025, 1413 Cancer, 255, 1101, 1251 Canities, 29 Captivity, 845 Carbonyl, 1495 Carbonyl groups, 221 Carboxymethyllysine, 1527 Cardiovascular disease, 1303 Carotid, 571 Catecholamines, 859 cDNA subtraction, 465 Cell injury, 1425 Cell membrane structure changes, 1425 Cell proliferation, 65, 1425 Cell replicative senescence, 1049 Cell stress, 599 Cellular aging, 487
0531-5565/01/$ - see front matter q 2001 Elsevier Science Inc. All rights reserved.
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Experimental Gerontology 36 (2001) 1825±1829
Cellular senescence, 607 Centarians, 327 Centenarians, 547, 899, 1063, 1663 Ceramide, 65 Cholinergic neurotransmission, 99 Chromosome, 1639 Circadian rhythm, 1083 Circadian rhythms, 267 Classical complement pathway, 1179 Clonality, 583 Clone, 89 Clutch, 829 Clutch size, 813 Collagen, 1527 Comet assay, 1483 Common tern, 833 Comparative gene-expression, 599 Comparative study, 791 Complex systems, 1277 Concanavalin A, 267 Confocal microscopy, 1483 Corpora allata, 723 Cost of reproduction, 1349 Crystallins, 1551 Cyclin-dependent kinase inhibitors, 1265 Cyclin-dependent kinases, 1265 Cyclins, 1265 Cyclooxygenase 2, 559 Cysteines, 1519 Cytokines, 1179, 1749 Damage, 1459 Deamidation, 1551 Deep sea, 739 Dehydroepiandrosterone, 1025, 1739 Dementia, 1251 Demography, 431 Denmark, 383 Depression, 298 Desipramine, 141 Desynchronization, 1083 Development, 695, 845 DHEA, 1075, 1739 Diacylglycerol, 1387 Different-aged cohorts, 687 Digital images, 1199 Digital light microscopy, 1199 Disease, 193 Disuse atrophy, 125 Diuretics, 571 DNA, 1459 DNA damage, 1483 DNA repair, 1049 DNA repair protein, 1483 DNA replication, 89 Donepezil, 353 Drosophila, 441, 723, 1137 Drosophila melanogaster, 1349
E2F, 1265 Egg size, 813 Elbow ¯exors, 1687 Elderly, 353, 571, 1727 Endocrinology, 177 Energy metabolism, 1539 Enzyme immunoassay, 341 Estrogen, 311 Evolution, 441 Evolution of senescence, 791 Exercise, 1699 Experimental gerontology, 383, 935, 947 External ®xation, 125 Extracellular matrix, 1565 Falls, 1251 Fatty acids, 65 Fibroblasts, 475, 607, 1327 Finland, 383 Fish, 765 Food restriction, 497, 1699 Fractures, 1749 Frailty, 915 Frailty model, 899 Free radicals, 1459 Freund's adjuvant, 267 GABA, 267 Gene, 1303 Gene chip, 1189 Gene expression, 465 Genetic Pathways, 1609 Genomic instability, 1619 Genotoxins, 1473 Geriatrics, 1581 Germ-line, 413 Geroprotectors, 1101 GH, 1075 Glutamate, 267 Glutathione, 1519 Glutathione S-transferases, 255 Glycation, 1527 Glycosylation, 869 GnRH, 859 Gompertz model, 845 Gonadotropins, 297, 1403 Grasshopper, 723 Graying, 29 Growth, 739, 765 Growth arrest, 1317 Guppies, 791 H1 zero mRNA Levels, 1649 Haemoconcentration, 571 Hair follicle, 29 Heat shock proteins, 341 HeLa cell, 465 Heteroduplex analysis, 583 Heterogeneity, 419, 1277
Experimental Gerontology 36 (2001) 1825±1829 Hippocampal neuronal degeneration, 295 Hippocampus, 232 Honey bee, 695 Hormone replacement, 1075 Hormone replacement therapy, 311 Housing, 159 hsp70, 1137 hTERT-melanocytes, 1265 Human, 99, 1251 Human cells, 89, 1639 Human ®broblasts, 65 Human senescent ®broblasts, 1317 Humans, 885 Humoral immune response, 519 HUVEC, 1327 Hydrogen peroxide, 1483 8-Hydroxy-2 0 -deoxyguanosine, 1375 Hypertensives, 571 Iceland, 383 IGF2 gene, 1663 Immortalization, 607, 1619 Immortalization of human cells, 487 Immune function, 311 Immune system, 583 Immunohistochemistry, 1179 Immunohistology, 1565 Immunosenescence, 519 Infectious disease, 245, 537 In¯ammation, 1179 In¯ammatory stress, 619 Inhibin B, 1403 INS gene, 1663 Inter-Alu PCR, 1063 Interferon-g, 1739 Interleukin 1b, 559 Interleukin-2, 1761 Interleukin-4, 537 Interleukin-6, 547 Intestine, 1727 Intrinsic senescence, 687 Isoaspartate formation, 1551 Isokinetic torque, 1687 J Haplogroup, 1161 Juvenile hormone, 723 Knock-out, 1289 l-carnitine, 1713 Leydig cells, 1361 l-glutamic acid, 231 Life extension, 1101 Life histories, 641 Life history evolution, 791 Life span, 431, 713, 1137 Life tables, 713 Life-history, 845 Lifespan, 1025
1827
Lifespan variation, 441 Linkage disequilibrium, 1663 Linker histone H1 zero, 1649 Linoleic acid, 1425 Lipid hydroperoxides, 1473 Lipid peroxidation, 221, 507, 1155, 1425 Lipids, 1413 Lipofuscin, 475, 1713 Lipopolysaccharide, 268, 1289 Liver, 255, 1387 Locomotor activity, 1137 Long-lived, 829 Long-lived organisms, 599 Longevity genes, 431 Longevity in trees, 651 Longevity, 419, 675, 713, 739, 765, 813, 1063, 1101, 1161, 1303, 1609 Lp(a), 1413 Lucigenin, 1361 Lung, 245, 537 Lymphocyte subsets, 267 Lymphocytes, 1749 Lysozyme, 141 Maillard, 1527 Male, 1075 Mammals, 845 Marine ®shes, 739 Mastication, 283 Mathematical model, 79 Mathematical models, 1049, 1277 Maturity, 765 Mechanical stress, 969 Medial thickening, 111 Melanocytes, 29 Melatonin, 297, 1075, 1083 Memory, 353 Menopause, 311 Metal-catalyzed oxidation, 1495 Microarray, 1189 Mitochondria, 957, 995, 1251, 1483 Mitochondrial DNA, 1161 Mitochondrial mutations, 1049 Mitochondrial superoxide generation, 1361 Mitotic HDFs, 1649 Molecular genetics, 1609 Molecular mechanisms of aging, 403 Monarch butter¯y, 723 Monkeys, 1025 Mononuclear cells, 1749 Morbidity, 885 Morphometry, 111 Mortality, 419, 713, 885, 1277 Mortality leveling off, 1277 Mortality rate, 687, 791 Mortality trajectory, 899 M. tuberculosis, 245 Multiple hormone systems, 177 Murine, 245
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Experimental Gerontology 36 (2001) 1825±1829
Muscle ®ber typing, 1673 Muscular activity, 1687 Mutated mitochondrial DNA, 619 Mutation-accumulation, 641 Mycobacterium tuberculosis, 537 Myocardium, 1155 Natural populations, 687 Negligible senescence, 593, 651 Neopterin, 1739 Nest success, 813 Neurodegeneration, 171 Neurodegenerative diseases, 1179 Neuroendocrine regulation, 859 Neurogeneration, 869 Nitrotyrosine, 221 Non-steroidal anti-in¯ammatory drugs, 559 Nonagenarians, 327, 899 Norepinephrine, 267 Norway, 383 Nutrition, 1251, 1727 Optical resolution, 1199 Osteoporosis, 547, 1251, 1749 Oxidation, 1527 Oxidative capacity, 1673 Oxidative damage resistance, 599 Oxidative damage, 619, 957, 1049 Oxidative defenses, 869 Oxidative DNA damage, 1375 Oxidative modi®cation, 1495 Oxidative stress, 441, 475, 641, 1251, 1349, 1483, 1503, 1609 Oxidative stress markers, 209 Oxidized proteins, 619 8-oxoG, 1483 p16 INK4a, 1289 p19 ARF, 1289 Palaeontology, 1565 Parkinson's disease, 1761 Parotid gland, 141 Pathophysiology, 1189, 1581 Pentosidine, 1527 Perimenopause, 297 Peroxidase, 141 Pharmacokinetics, 1083 Phenobarbital, 255 Phosphatidate phosphohydrolase, 1387 Phosphatidic acid, 1387 Physiological aging, 675 Pinus longaeva, 675 Pineal gland, 297 Pituitary-gonadal axis, 1403 Plants, 687 Pleiotropy, 641 Poecilia reticulata, 791 Poly(ADP-ribose)polymerase (PARP), 1049 Polymorphism, 1161
Postmitotic senescent HDFs, 1649 Predation, 791 Prion diseases, 1551 Priority areas, 403 Pro-in¯ammatory phenotype, 171 Programmed death of organism, 995 Proin¯ammatory cytokines, 619 Proliferative potential, 1639 Prostaglandin E2, 559 Prostaglandins, 65 Protected populations, 687 Protein aging, 1565 Protein methyltransferase, 1551 Protein modi®cation, 1495 Protein oxidation, 221, 1503 Protein repair, 1551 Protein turnover, 1495 Proteolysis, 475 Purinergic neurotransmission, 99 Quail, 859 Radicals, 1503 Radiochemistry, 739 Rat, 159, 231, 507, 1361, 1375, 1699 Rat liver, 497 Rate of aging, 1277 Rats, 125 Reactive oxidants, 1609 Reactive oxygen species, 619, 869, 995, 1425, 1473, 1503, 1539 Reactive oxygen species (ROS), 1251 Regulatory peptides, 1727 REM sleep, 353 Remobilisation, 125 Repair, 1251 Repetitive sequences, 1063 Replicative senescence, 65, 79 Reproduction, 431, 833, 859 Reproductive aging, 859 Reproductive diapause, 723 Reproductive frequency, 813 Reproductive longevity, 829 Research models, 3 Research trends, 947 Rock®shes, 739 Rodents, 1025 S100C, 1317 Saliva, 141 Salmonids, 765 SAMP8 mice, 283 Scorpaenidae, 739 Seabird, 833 Selection for longevity, 441 Selenium, 327 Senescence, 89, 193, 413, 465, 475, 675, 723, 791, 813, 829, 833, 845, 869, 1251, 1327, 1609
Experimental Gerontology 36 (2001) 1825±1829 Senescence-accelerated mouse, 111 Senile dementia, 283 Serum, 341 Serotonin, 267 Sex and ageing, 413 Sex-dependent in¯uence, 1303 Sexual behavior, 859 Shear stress, 571 Shear wave propagation, 363 Signaling, 969 single nucleotide polymorphism, 1189 Site-speci®c modi®cation, 1495 Skeletal muscle, 125 Skin anisotropy,, 363 Skin tension line, 363 Sleep, 1083 Sleep apnea, 1673 Slow aging, 593, 915 Slow growth, 651 Smooth muscle cells, 969 Social insects, 695 Soluble gp130, 547 Soluble IL-6 receptor, 547 Spatial memory, 283 Sterna hirundo, 833 Stochastic processes, 79 Stress, 607, 1049, 1155 Stress resistance, 441, 1349, 1609 Submaxillary lymph nodes, 267 Succinate dehydrogenase, 1673 Sulfhydryls, 1519 Supercentenarians, 899, 915 Surgery, 1727 Survival, 159, 833, 1699 Survival analysis, 1303 Survivorship, 1277 Sweden, 383
Systolic blood pressure, 111 T, 1075 gd T cell, 245 T cell receptor, 583 T cells, 1761 Taurine, 267 Telomerase, 607, 1265, 1619 Telomere, 1639 Telomere binding proteins, 1619 Telomere loss, 1049 Telomere structure, 1619 Telomere shortening, 89 Telomeres, 193, 475, 607, 1251 Terrapene carolina triunguis, 829 Terns, 859 Testis, 1361 TH gene, 1663 Thyroid function, 297 Thermotolerance, 1609 Thuja occidentalis, 651 Trade-offs, 641 Translational research, 193 Trout, 765 Tumor suppression, 607, 1619 Tumor suppressors, 1289 Two-dimensional gel electrophoresis, 487 Upper airway muscles, 1673 Urinary aldehydes, 507 Validation, 739 Vascular diseases, 1251 Weibull model, 845 Zinc, 327
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Experimental Gerontology 36 (2001) 1825±1829
Keyword Index Acetylcholine, 99 Activin A, 1403 Adaptation, 1727 Adaptive cellular response, 1539 Advanced glycation end-products, 1527 Advanced glycosylation endoproducts, 869 A¯atoxin B1, 255 Age, 739 Age-associated disabilities, 3 Age-dependent mortality, 687 Age-independent mortality, 687 Ageing, 125, 159, 245, 475, 497, 583, 641, 947, 1221, 1375, 1503, 1699, 1739 Ageing model, 899 Ageing research, 383, 935 Aging, 3, 99, 111, 177, 193, 209, 221, 255, 267, 311, 327, 341, 441, 507, 519, 547, 675, 695, 813, 869, 957, 969, 995, 1063, 1075, 1083, 1101, 1137, 1155, 1189, 1251, 1361, 1387, 1403, 1413, 1425, 1551, 1565, 1639, 1673, 1687, 1713 Aging and in¯ammation, 619 Aging biomarkers, 1277 Aging mutants, 1609 Aging of organisms, 651 Aging-related mortality, 845 Alloimmune response, 1761 Aluminium, 231 alpha-2-Macroglobulin, 487 Alu repeats, 1063 Alzheimer's Disease (AD), 1251 Alzheimer's disease, 171, 487, 559, 1179, 1551 Amantadine treatment, 1761 Amylase, 141 Animal, 1727 Antagonist co-activation, 1687 Antagonistic pleiotropy, 607, 1619 Antigen presenting cells, 519 Antioxidant, 327, 441 Antioxidants, 209, 1713 Aorta, 111 Apis mellifera, 695 Apoptosis, 311, 969, 995, 1251, 1327 Arachidonic acid, 65 Aspartate, 267 Astrocyte, 231
Atherosclerosis, 969, 1413, 1425 ATP, 99 Atropine-resistant contraction, 99 Autoimmunity, 519 Autophagy lysosomal proteolysis, 497 Bacterial-feeding nematode, 431 Basic gerontological research, 403 B cells, 537, 1761 Beverton, 765 Biodemography, 419 Bioimpedance, 159, 1699 Biological aging, 1539 Biological gerontology, 1221 Biomedical gerontology, 1221, 1581 Bird longevity, 599 Birds, 641, 845, 869 Bladder smooth muscle, 99 Blanding's turtle, 813 Blindness, 1083 Body composition, 159, 1699 Body mass index, 363 Box turtle, 829 Brain, 1387, 1713 Brain and aging, 859 Brain size, 845 Bristlecone pine, 675 5-Bromodeoxyuridine, 465 Caenorhabditis elegans, 431 Calcium regulatory proteins, 1539 Calorie restriction, 1025, 1413 Cancer, 255, 1101, 1251 Canities, 29 Captivity, 845 Carbonyl, 1495 Carbonyl groups, 221 Carboxymethyllysine, 1527 Cardiovascular disease, 1303 Carotid, 571 Catecholamines, 859 cDNA subtraction, 465 Cell injury, 1425 Cell membrane structure changes, 1425 Cell proliferation, 65, 1425 Cell replicative senescence, 1049 Cell stress, 599 Cellular aging, 487
0531-5565/01/$ - see front matter q 2001 Elsevier Science Inc. All rights reserved.
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Experimental Gerontology 36 (2001) 1825±1829
Cellular senescence, 607 Centarians, 327 Centenarians, 547, 899, 1063, 1663 Ceramide, 65 Cholinergic neurotransmission, 99 Chromosome, 1639 Circadian rhythm, 1083 Circadian rhythms, 267 Classical complement pathway, 1179 Clonality, 583 Clone, 89 Clutch, 829 Clutch size, 813 Collagen, 1527 Comet assay, 1483 Common tern, 833 Comparative gene-expression, 599 Comparative study, 791 Complex systems, 1277 Concanavalin A, 267 Confocal microscopy, 1483 Corpora allata, 723 Cost of reproduction, 1349 Crystallins, 1551 Cyclin-dependent kinase inhibitors, 1265 Cyclin-dependent kinases, 1265 Cyclins, 1265 Cyclooxygenase 2, 559 Cysteines, 1519 Cytokines, 1179, 1749 Damage, 1459 Deamidation, 1551 Deep sea, 739 Dehydroepiandrosterone, 1025, 1739 Dementia, 1251 Demography, 431 Denmark, 383 Depression, 298 Desipramine, 141 Desynchronization, 1083 Development, 695, 845 DHEA, 1075, 1739 Diacylglycerol, 1387 Different-aged cohorts, 687 Digital images, 1199 Digital light microscopy, 1199 Disease, 193 Disuse atrophy, 125 Diuretics, 571 DNA, 1459 DNA damage, 1483 DNA repair, 1049 DNA repair protein, 1483 DNA replication, 89 Donepezil, 353 Drosophila, 441, 723, 1137 Drosophila melanogaster, 1349
E2F, 1265 Egg size, 813 Elbow ¯exors, 1687 Elderly, 353, 571, 1727 Endocrinology, 177 Energy metabolism, 1539 Enzyme immunoassay, 341 Estrogen, 311 Evolution, 441 Evolution of senescence, 791 Exercise, 1699 Experimental gerontology, 383, 935, 947 External ®xation, 125 Extracellular matrix, 1565 Falls, 1251 Fatty acids, 65 Fibroblasts, 475, 607, 1327 Finland, 383 Fish, 765 Food restriction, 497, 1699 Fractures, 1749 Frailty, 915 Frailty model, 899 Free radicals, 1459 Freund's adjuvant, 267 GABA, 267 Gene, 1303 Gene chip, 1189 Gene expression, 465 Genetic Pathways, 1609 Genomic instability, 1619 Genotoxins, 1473 Geriatrics, 1581 Germ-line, 413 Geroprotectors, 1101 GH, 1075 Glutamate, 267 Glutathione, 1519 Glutathione S-transferases, 255 Glycation, 1527 Glycosylation, 869 GnRH, 859 Gompertz model, 845 Gonadotropins, 297, 1403 Grasshopper, 723 Graying, 29 Growth, 739, 765 Growth arrest, 1317 Guppies, 791 H1 zero mRNA Levels, 1649 Haemoconcentration, 571 Hair follicle, 29 Heat shock proteins, 341 HeLa cell, 465 Heteroduplex analysis, 583 Heterogeneity, 419, 1277
Experimental Gerontology 36 (2001) 1825±1829 Hippocampal neuronal degeneration, 295 Hippocampus, 232 Honey bee, 695 Hormone replacement, 1075 Hormone replacement therapy, 311 Housing, 159 hsp70, 1137 hTERT-melanocytes, 1265 Human, 99, 1251 Human cells, 89, 1639 Human ®broblasts, 65 Human senescent ®broblasts, 1317 Humans, 885 Humoral immune response, 519 HUVEC, 1327 Hydrogen peroxide, 1483 8-Hydroxy-2 0 -deoxyguanosine, 1375 Hypertensives, 571 Iceland, 383 IGF2 gene, 1663 Immortalization, 607, 1619 Immortalization of human cells, 487 Immune function, 311 Immune system, 583 Immunohistochemistry, 1179 Immunohistology, 1565 Immunosenescence, 519 Infectious disease, 245, 537 In¯ammation, 1179 In¯ammatory stress, 619 Inhibin B, 1403 INS gene, 1663 Inter-Alu PCR, 1063 Interferon-g, 1739 Interleukin 1b, 559 Interleukin-2, 1761 Interleukin-4, 537 Interleukin-6, 547 Intestine, 1727 Intrinsic senescence, 687 Isoaspartate formation, 1551 Isokinetic torque, 1687 J Haplogroup, 1161 Juvenile hormone, 723 Knock-out, 1289 l-carnitine, 1713 Leydig cells, 1361 l-glutamic acid, 231 Life extension, 1101 Life histories, 641 Life history evolution, 791 Life span, 431, 713, 1137 Life tables, 713 Life-history, 845 Lifespan, 1025
1827
Lifespan variation, 441 Linkage disequilibrium, 1663 Linker histone H1 zero, 1649 Linoleic acid, 1425 Lipid hydroperoxides, 1473 Lipid peroxidation, 221, 507, 1155, 1425 Lipids, 1413 Lipofuscin, 475, 1713 Lipopolysaccharide, 268, 1289 Liver, 255, 1387 Locomotor activity, 1137 Long-lived, 829 Long-lived organisms, 599 Longevity genes, 431 Longevity in trees, 651 Longevity, 419, 675, 713, 739, 765, 813, 1063, 1101, 1161, 1303, 1609 Lp(a), 1413 Lucigenin, 1361 Lung, 245, 537 Lymphocyte subsets, 267 Lymphocytes, 1749 Lysozyme, 141 Maillard, 1527 Male, 1075 Mammals, 845 Marine ®shes, 739 Mastication, 283 Mathematical model, 79 Mathematical models, 1049, 1277 Maturity, 765 Mechanical stress, 969 Medial thickening, 111 Melanocytes, 29 Melatonin, 297, 1075, 1083 Memory, 353 Menopause, 311 Metal-catalyzed oxidation, 1495 Microarray, 1189 Mitochondria, 957, 995, 1251, 1483 Mitochondrial DNA, 1161 Mitochondrial mutations, 1049 Mitochondrial superoxide generation, 1361 Mitotic HDFs, 1649 Molecular genetics, 1609 Molecular mechanisms of aging, 403 Monarch butter¯y, 723 Monkeys, 1025 Mononuclear cells, 1749 Morbidity, 885 Morphometry, 111 Mortality, 419, 713, 885, 1277 Mortality leveling off, 1277 Mortality rate, 687, 791 Mortality trajectory, 899 M. tuberculosis, 245 Multiple hormone systems, 177 Murine, 245
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Experimental Gerontology 36 (2001) 1825±1829
Muscle ®ber typing, 1673 Muscular activity, 1687 Mutated mitochondrial DNA, 619 Mutation-accumulation, 641 Mycobacterium tuberculosis, 537 Myocardium, 1155 Natural populations, 687 Negligible senescence, 593, 651 Neopterin, 1739 Nest success, 813 Neurodegeneration, 171 Neurodegenerative diseases, 1179 Neuroendocrine regulation, 859 Neurogeneration, 869 Nitrotyrosine, 221 Non-steroidal anti-in¯ammatory drugs, 559 Nonagenarians, 327, 899 Norepinephrine, 267 Norway, 383 Nutrition, 1251, 1727 Optical resolution, 1199 Osteoporosis, 547, 1251, 1749 Oxidation, 1527 Oxidative capacity, 1673 Oxidative damage resistance, 599 Oxidative damage, 619, 957, 1049 Oxidative defenses, 869 Oxidative DNA damage, 1375 Oxidative modi®cation, 1495 Oxidative stress, 441, 475, 641, 1251, 1349, 1483, 1503, 1609 Oxidative stress markers, 209 Oxidized proteins, 619 8-oxoG, 1483 p16 INK4a, 1289 p19 ARF, 1289 Palaeontology, 1565 Parkinson's disease, 1761 Parotid gland, 141 Pathophysiology, 1189, 1581 Pentosidine, 1527 Perimenopause, 297 Peroxidase, 141 Pharmacokinetics, 1083 Phenobarbital, 255 Phosphatidate phosphohydrolase, 1387 Phosphatidic acid, 1387 Physiological aging, 675 Pinus longaeva, 675 Pineal gland, 297 Pituitary-gonadal axis, 1403 Plants, 687 Pleiotropy, 641 Poecilia reticulata, 791 Poly(ADP-ribose)polymerase (PARP), 1049 Polymorphism, 1161
Postmitotic senescent HDFs, 1649 Predation, 791 Prion diseases, 1551 Priority areas, 403 Pro-in¯ammatory phenotype, 171 Programmed death of organism, 995 Proin¯ammatory cytokines, 619 Proliferative potential, 1639 Prostaglandin E2, 559 Prostaglandins, 65 Protected populations, 687 Protein aging, 1565 Protein methyltransferase, 1551 Protein modi®cation, 1495 Protein oxidation, 221, 1503 Protein repair, 1551 Protein turnover, 1495 Proteolysis, 475 Purinergic neurotransmission, 99 Quail, 859 Radicals, 1503 Radiochemistry, 739 Rat, 159, 231, 507, 1361, 1375, 1699 Rat liver, 497 Rate of aging, 1277 Rats, 125 Reactive oxidants, 1609 Reactive oxygen species, 619, 869, 995, 1425, 1473, 1503, 1539 Reactive oxygen species (ROS), 1251 Regulatory peptides, 1727 REM sleep, 353 Remobilisation, 125 Repair, 1251 Repetitive sequences, 1063 Replicative senescence, 65, 79 Reproduction, 431, 833, 859 Reproductive aging, 859 Reproductive diapause, 723 Reproductive frequency, 813 Reproductive longevity, 829 Research models, 3 Research trends, 947 Rock®shes, 739 Rodents, 1025 S100C, 1317 Saliva, 141 Salmonids, 765 SAMP8 mice, 283 Scorpaenidae, 739 Seabird, 833 Selection for longevity, 441 Selenium, 327 Senescence, 89, 193, 413, 465, 475, 675, 723, 791, 813, 829, 833, 845, 869, 1251, 1327, 1609
Experimental Gerontology 36 (2001) 1825±1829 Senescence-accelerated mouse, 111 Senile dementia, 283 Serum, 341 Serotonin, 267 Sex and ageing, 413 Sex-dependent in¯uence, 1303 Sexual behavior, 859 Shear stress, 571 Shear wave propagation, 363 Signaling, 969 single nucleotide polymorphism, 1189 Site-speci®c modi®cation, 1495 Skeletal muscle, 125 Skin anisotropy,, 363 Skin tension line, 363 Sleep, 1083 Sleep apnea, 1673 Slow aging, 593, 915 Slow growth, 651 Smooth muscle cells, 969 Social insects, 695 Soluble gp130, 547 Soluble IL-6 receptor, 547 Spatial memory, 283 Sterna hirundo, 833 Stochastic processes, 79 Stress, 607, 1049, 1155 Stress resistance, 441, 1349, 1609 Submaxillary lymph nodes, 267 Succinate dehydrogenase, 1673 Sulfhydryls, 1519 Supercentenarians, 899, 915 Surgery, 1727 Survival, 159, 833, 1699 Survival analysis, 1303 Survivorship, 1277 Sweden, 383
Systolic blood pressure, 111 T, 1075 gd T cell, 245 T cell receptor, 583 T cells, 1761 Taurine, 267 Telomerase, 607, 1265, 1619 Telomere, 1639 Telomere binding proteins, 1619 Telomere loss, 1049 Telomere structure, 1619 Telomere shortening, 89 Telomeres, 193, 475, 607, 1251 Terrapene carolina triunguis, 829 Terns, 859 Testis, 1361 TH gene, 1663 Thyroid function, 297 Thermotolerance, 1609 Thuja occidentalis, 651 Trade-offs, 641 Translational research, 193 Trout, 765 Tumor suppression, 607, 1619 Tumor suppressors, 1289 Two-dimensional gel electrophoresis, 487 Upper airway muscles, 1673 Urinary aldehydes, 507 Validation, 739 Vascular diseases, 1251 Weibull model, 845 Zinc, 327
1829