Large loop excision of the transformation zone. A practical guide to LLETZ

Large loop excision of the transformation zone. A practical guide to LLETZ

36 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. CURRENT OBSTETRICS AND GYNAECOLOGY medullary collecting tubular cell culture. Biochem Biophys Res Commu...

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CURRENT OBSTETRICS AND GYNAECOLOGY medullary collecting tubular cell culture. Biochem Biophys Res Commun 1989; 160: 1169-74 Lins LE. Reversible renal failure caused by hypercalcemia. Acta Med Stand 1978; 203: 309-14 O’Leary JA. Ten-year study of sarcoidosis and pregnancy. Am J Obstet Gynecol 1962; 84: 462-66 Mayock RL, Sullivan RD, Greening RR, Jones R Jr. Sarcoidosis and pregnancy. JAMA 1957; 164: 158-63 Selroos 0. Sarcoidosis and pregnancy: a review with results of a retrospective survey. J Intern Med 1990; 227: 221-24 Donaldson SW, Tompsett AC, Grekin RH, Curtis AC. Sarcoidosis. V. The effects of pregnancy on the course of the disease. Ann Intern Med 1951; 34: 1213-18 de Regt RH. Sarcoidosis and pregnancy. Obstet Gynecol 1987; 70: 369-72 Abarquez C, Pandya K, Sharma OP. Sarcoidosis and pregnancy. Clinical observation. Sarcoidosis 1990; 7: 63-66 Agha FP, Vade A, Amendola MA, Cooper RF. Effects of pregnancy on sarcoidosis. Surg Gynecol Obstet 1982; 155: 817-22 Reisfield DR. Boeck’s sarcoid and pregnancy. Am J Obstet Gynecol 1958; 75: 795-801 Eggelmeijer F, Dijkmans BAC. Sarcoidosis post partum: a description of four cases. Br J Rheumatol 1989; 28: 270-71

23. Waren GV, Sprague SM, Corwin HL. Sarcoidosis presenting as acute renal failure during pregnancy. Am J Kidney Dis 1988; 12: 161-63 24. Jungers P, Houillier P, Forget D, Henry-Amar M. Specific controversies concerning the natural history of renal disease in pregnancy. Am J Kidney Dis 1991; 17: 116-22 27. Lindheimer MD, Katz AI. Gestation in women with kidney disease: prognosis and management. Bailliere’s Clin Obstet Gynecol 1987; 1: 921-37 29. Abe S. An overview of pregnancy in women with underlying renal disease. Am J Kidney Dis 1991; 17: 112-15 30. Hou SH, Grossman SD, Madias NE. Pregnancy in women with renal disease and moderate renal insulliciency. Am J Med 1985; 78: 185-94 31. Abe S, Amagasaki Y, Konishi K, Kato E, Sakaguchi H, Iyori S. The influence of antecedent renal disease on pregnancy. Am J Obstet Gynecol 1985; 153: 508-14 32. Hata T, Hata K, Aoki S, Takamiya 0, Murao K, Kitao M. Renal arterial blood flow velocity waveforms in pregnant women. Am J Obstet Gynecol 1987; 157: 1269971 33. Levine AB, Lockwood CJ, Chitkara U, et al. Maternal renal artery Doppler velocimetry in normotensive pregnancies and pregnancies complicated by hypertensive disorders. Obstet Gynecol 1992; 79: 264-67

1 Book reviews

Large loop excision of the transformation zone. A practical guide to LLETZ by Walter Prendiville. Chapman & Hall Medical. Price: g60 ISBN 0-412-46240-O The introduction of LLETZ has been a valuable addition to those methods currently available for the treatment of CIN in that it can usually be performed in the outpatient Colposcopy Clinic under local anaesthesia, but even more important is the ability of the technique to remove all of the potentially abnormal epithelium which can then be sent for histological assessment and exclusion of unsuspected invasive carcinoma. Sadly, the ease with which it can be used has led, in many hospitals, to a situation in which many women are subjected to LLETZ when a more conservative approach may well have avoided treatment: in addition a source of great concern throughout the world is that it is leading to a lowering of the basic standards necessary for competent colposcopy. This book is therefore essential reading for those

who wish to perform LLETZ. The opening chapter by Rene Cartier (who first popularised the use of the diathermy loop) is an excellent starting point for those who wish to perform LLETZ making it clear that there is more to colposcopy than simply applying acetic acid to the cervix and removing any tissue which is acetowhite! The remaining chapters describe the physics of electrosurgery (essential to an understanding of how the loop works), direction of patients, techniques for treating premalignant disease of the cervix, vagina, vulva and peri-anal areas and the follow-up after treatment. Comparison of LLETZ with other methods is reviewed thoroughly, and finally the chapter by Ian Duncan on the results of the National Health Service Cervical Screening Programme summarises clearly the published guidelines for good, safe clinical practice and the management of cervical screening programmes. In summary a first class book, written by those who are experts in their own fields. J. JORDAN