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of the tongue." Intraoral examination revealed a sessile nodule of asymptomatic white color with firm consistency and palpation of regular shape and surface, measuring approximately 7 mm, with an evolution time of approximately 2 years and located in the tongue. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of giant cell fibroma. The patient is under follow-up with no recurrence.
FIBROLIPOMA OF THE ORAL CAVITY CASE REPORT. EMERSON LUCAS DA SILVA COIMBRA, JOSE DE ASSIS SILVA JUNIOR, ^ A, ANA FLAVIA WILLIAM NAPOLITANO CORRE e SCHUELER DE ASSUMP¸C AO LEITE, SIMONE DE ^ QUEIROZ CHAVES LOURENCO ¸ and, MONICA LAGE DA ROCHA Fibrolipoma is a benign tumor characterized by the presence of mature adipose cells separated by areas of dense fibroconnective tissue. This tumor can affect any part of the body, but it is rare in the oral cavity. The objective of this study is to present a case of fibrolipoma in a 67-year-old white woman with a complaint of "lesion in buccal mucosa." The patient has drug-controlled hypertension. At the intraoral examination, an asymptomatic pediculated nodule of pink color with firm consistency and smooth surface measuring approximately 19 mm and located in the buccal mucosa was identified. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of fibrolipoma. The patient is under follow-up with no recurrence.
INTRAOSSEOUS BENIGN FIBROUS HISTIOCYTOMA RICH IN GRANULAR CELLS OF THE MAXILLA: IMMUNOHISTOCHEMICAL ANALYSIS. ROSE MARA ORTEGA, MATHEUS HENRIQUE LOPES DOMINGUETE, KAMILA PRADO PEREIRA GRACIANO DOMINGUETE, CATIA MARISA GAZOLLA DE OLIVEIRA, LUCIANA YAMAMOTO ALMEIDA, LUCAS RIBEIRO TEIXEIRA and, JORGE ESQUICHE LEON Benign fibrous histiocytoma (BFH) is a mesenchymal tumor usually constituted of spindle and epithelioid cells, which occurs predominantly in the bone and soft tissues. Histopathologically, it reveals 2 types of cells, fibroblasts and histiocytes, arranged in storiform pattern and interlacing fascicles without nuclear pleomorphism, necrosis, and low mitotic activity. The granular cell variant of BFH is extremely rare. A 64-year-old woman was referred presenting an osteolytic lesion in the anterior region of the maxilla, mimicking nasopalatine duct cyst. After excisional biopsy, microscopy revealed a storiform arrangement of spindle to epithelioid cells, most of them with PAS-D positive granular cytoplasm, surrounded by sclerotic fibrous stroma. Immunohistochemistry showed positivity for vimentin, CD68, CD163, a smooth muscle actin, and focal FXIIIA. Ki-67 was <3%. The patient presented well after 1-year of follow-up. To our knowledge, this is the first report of BFH rich in granular cells in intraosseous location affecting the maxilla.
LASER THERAPY FOR TREATMENT OF ORAL MUCOSITIS: CASE REPORT. ELISA KAUARK e BISPO, HAYANA FONTES, MAYARA SIMOES RAMOS LIMA, JULIANA BORGES DE LIMA DANTAS,
OOOO January 2020 MANOELA CARRERA MARTINEZ PEREIRA, ALENA RIBEIRO ALVES PEIXOTO MEDRADO and, GABRIELA MARTINS BOTELHO A 60-year-old male patient with a history of chronic drinking and smoking was diagnosed as having squamous cell carcinoma on the tongue beyond surgical therapeutic possibility. Radiotherapy and chemotherapy were indicated. After the fifth cycle of chemotherapy concomitant with radiotherapy, the patient reported pain in the oral cavity, which worsened after the use of methotrexate to treat peripheral neuropathy. The condition progressed to extensive oral ulcers requiring the use of a nasogastric tube for feeding. Low-intensity laser (AsGaAl, 680 nm, 2 J/cm2) was applied on the ulcers in a punctual and continuous manner. After 4 sessions, there was a significant improvement of the condition, with catheter removal and the patient being released from the hospital. The laser therapy proved to be effective in the treatment of oral mucositis lesions, reducing the pain and severity of the lesions, being a noninvasive and safe form of treatment.
GRANULAR CELL TUMOR OF LOWER LIP: CASE REPORT. LUIZA DE MOURA CARVALHO FIGUEIRA, LILIAN MACHADO DE SOUSA ALMEIDA, RAFAELA ELVIRA ROZZA-DEMENEZES, ADRIANNA MILAGRES, DANIELLE CASTEX CONDE, ELIANA PEDRA DIAS and, KARIN SOARES GONCALVES ¸ CUNHA Granular cell tumor is a rare benign soft-tissue neoplasm with a predilection for the mouth. Its most common location is in the tongue followed by buccal mucosa. There is a predilection for the female sex, and it occurs most often between the fourth and sixth decade. It is usually normochromic, but occasionally it may present a yellow coloration. Our aim is to report a case of a 21-year-old black male patient presenting a firm yellowish sessile nodule, measuring 1 cm in the lower lip with an evolution of 3 years. The clinical diagnoses were fibrolipoma and traumatic fibroma. An excisional biopsy was performed, and in the histopathologic examination a proliferation of large and polygonal cells with abundant eosinophilic and granular cytoplasm and vesicular nuclei were observed, leading to the diagnosis of granular cell tumor. The patient has been followed up for 5 months, and no recurrence was observed.
LASER THERAPY AS ADJUNCTIVE TREATMENT FOR ORAL MUCOSITIS IN A PEDIATRIC PATIENT WITH NON-HODGKIN LYMPHOMA. LARISSA GABRIELY OLIVEIRA CAVALCANTI, JULIANELLY ALVES BISERRA, JULIANA ^ LO CAVALCANTE DE OLIVEIRA, MORGANA RABE RODRIGUES LAFAYETTE DE OLIVEIRA, MARIA ^ GABRIELA CAVALCANTI DE ARAUJO, MONICA MOREIRA DIAS CRUZ and, JOSE ANCHIETA DE BRITO Lymphomas represent the third most common type of cancer in young people, classified into non-Hodgkin (NHL) or Hodgkin lymphoma. NHL arises when B or T cells, which are involved in the protection, become malignant, growing uncontrollably, "contaminating" the lymphatic system. Characterized by a high degree of malignancy with pathology and immunology of different characteristics. Radiotherapy or chemotherapy are treatments performed for this disease, which may lead to oral manifestations because of its cytotoxicity. A 13-year-old male patient diagnosed
OOOO Volume 129, Number 1 as having NHL presented during treatment white pseudomembrane and erythematous ulcers, painful to the touch in regions of the buccal mucosa and bilateral border of the tongue, suggestive of mucositis. As a therapeutic option, we performed photodynamic and low-level laser therapy in association with pharmacologic and local hygiene because of immunosuppression, obtaining remission of the lesions after 7 days. Laser therapy is a noninvasive, adjuvant tool that promotes analgesic, anti-inflammatory and biostimulating effects.
TREATMENT OF ORAL CHRONIC GRAFTVS-HOST DISEASE WITH CLOBETASOL: CASE REPORT. BARBARA BARRETO PACHECO VALENTIM, GABRIELA DE ASSIS RAMOS, e CAMILA BRANDAO LOBO, TAISA DOMINGUES BERNARDES SILVA and, HELITON SPINDOLA ANTUNES Graft-vs-host disease (GVHD) is the main complication of allogeneic hematopoietic stem cells transplantation. A 29-yearold Brazilian man was diagnosed as having severe aplastic anemia and submitted to allogeneic HSCT in October 2013. He developed systemic chronic GVHD, including the oral cavity (lichenoid lesions in right and left buccal mucosa and labial hyperchromia and was treated with mycophenolate mofetil, tacrolimus, cyclosporine, and dexamethasone solution [mouthwash]). Upon stabilization of chronic GVHD in the oral cavity, the patient displayed gingival atrophy and erythema (12-21/3342) on July 27, 2017. Dexamethasone mouthwash and tacrolimus ointment was unsuccessful. On November 11, 2017, the patient was instructed to use clobetasol gel 0.05% on individual tray 4 times/d/15 min. The total regression of gingival chronic GVHD was observed within 22 days. On January 1, 2018, the patient presented relapse of gingival erythema (12-21) with worsening of condition due to treatment discontinuation. We observed that clobetasol on individual tray was effective in this case.
CLINICAL-SURGICAL APPROACH FOR DIAGNOSIS AND TREATMENT OF GIANT OSSIFYING FIBROMA: CASE REPORT. BRUNA JUNGER, CASSIO MESSIAS BEIJA FLOR FIGUEIREDO, GABRIEL MULINARI DOS SANTOS, LAIS SARA EGAS MUNIZ BARRETO VALLE, GUSTAVO ANTONIO CORREA MOMESSO, TARIK OCON BRAGA POLO and, FRANCISLEY AVILA SOUZA Rarely, the giant ossifying fibroma is a neoplasm with high growth potential. These lesions have frequently been associated with heterogeneous clinical and radiographic features, leading to difficulty in diagnosis. Generally, peripheral ossifying fibroma presents predilection for the female sex as well as by the jaw region and affects patients of variable age. This paper aims to report the clinical-surgical approach of a case of extensive ossifying fibroma in the right mandibular region, clinically mimicking a malignant lesion, and its histologic characteristics that led to the establishment of the diagnosis.
LEUKEMIC INFILTRATION IN TONGUE. JULIA STEPHANIE BRUNO, WANESSA MIRANDA-SILVA, BERNAR MONTEIRO BENITES, CLAUDIA PARAHYBA, FELIPE PAIVA DA FONSECA and, EDUARDO RODRIGUES FREGNANI
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Soft tissue changes in the oral cavity associated with leukemia such as oral bleeding, mucosal petechiae, mucosal ulceration, and infection are commonly described. Leukemic cells may infiltrate the oral cavity as leukemic infiltration to the gingival tissue but rarely involve other areas. The objective of this report is to describe a case of leukemic infiltration (myeloid sarcoma) in the oral cavity. A 48-year-old male patient was admitted to our service complaining of malaise, fever, and gingival bleeding. At clinical examination, beyond the gingival bleeding involvement, a rare clinical presentation characterized by the development of a persistent ulceration on the lateral border of the tongue was observed, which biopsy results showed the presence of infiltration of immature cells with scarce cytoplasm and hyperchromatic nucleus. Blood test revealed 119.000/mm3 leukocytes, whereas the myelogram demonstrated 87% of blasts carrying a myeloid differentiation confirmed by flow cytometry positivity confirming the diagnosis of acute myeloid leukemia.
HEMANGIOLYMPHANGIOMA IN SUBMANDIBULAR REGION: A CASE REPORT. ELIANDRO DE SOUZA FREITAS, RENATA GUALBERTO DA CUNHA, MILENA GOMES MELO LEITE, YAMILLE DE LIMA SOUZA, THAYS MORAIS ALVES, FRANCISCO AMADIS BATISTA FERREIRA and, JECONIAS CAMARA Hemangiolymphangiomas are rare vascular malformations of both lymphatic and blood vessels in which 80% to 90% are diagnosed during the first 2 years of life. This study highlight the case report of a 25-year-old male patient admitted to the hospital complaining about right submandibular region swelling for approximately 1 year. On clinical examination, he presented a painless lesion with rapid and progressive growth and soft consistency. The tomographic and ultrasound results showed a hypodense and circumscribed lesion with cystic appearance content, measuring 2.1 £ 5.7 £ 2.0 cm, with lymphadenomegaly unilateral of inflammatory appearance. Excisional biopsy was performed, and histopathologic analysis revealed proliferation of vascular spaces coated with thin and thick layers of endothelial cells, sometimes exhibiting congestion or thrombosis besides extravasations of protein material similar to lymph with diagnosis of hemangiolymphangioma. The patient is under follow-up showing no signs of recurrence.
ODONTOGENIC TUMOR IN THE MAXILLA: SURGICAL APPROACH THROUGH THE WEBER-FERGUSON ACCESS. CASE REPORT. PAULO ARAMBURU, BRISA DOS SANTOS LEITE, MARIA APARECIDA DE ALBUQUERQUE CAVALCANTE, DANIELLE ARAUJO MARTINS and, ITALO HONORATO ALFREDO GANDELMANN The calcifying epithelial odontogenic tumor (CEOT) is characterized as a rare benign lesion, affecting the mandible and maxilla in a ratio of 2:1, showing slow growth, though locally aggressive, with a peak of incidence between the ages of 30 to 50 years with no sex predilection. The case reported here highlights the surgical treatment of a CEOT in the maxilla performed through the Weber-Ferguson approach, which provided a satisfactory surgical field for the complete enucleation and tumor curettage.