LB022-SUN MICRONUTRIENT STATUS IN IBD PATIENTS

LATE BREAKING ABSTRACTS I Methods: The stress was diagnosed by means of the instrument “Stress Symptoms Inventory for Adults Lipp” [1] and the sample was stratified into two groups (with and without stress). We used questionnaires to identify and to characterize the DSD; some questions to map qualitative situations of consumption of sugars; and seven food records to estimate the average daily intake of sugars. An experiment was simulated to analyze the usual addition of sugar in bitter drink (coffee) and acid drink (iced passion fruit). Results: Fifty-seven women participated in the study, 31 with stress (54.38%) and 26 without stress (45.61%). The SSD was found in 32 women, and 77.42% of them were also stressed (p < 0.01). Comparing women with and without SSD, 81.25% of women with SSD using the candy to improve mood; 75% need increasing amounts to feel good; 81.25% feel symptoms in the absence of sweet; 93.75% said they always eat more sweets than they intended; 71.88% spend hours thinking about how to acquire them; 40.62% said they have stopped doing any activity to be eating sweet; and 81.25% still eating these foods even though they can cause problems (p < 0.01). The variety, amount of sweets, and eating behaviors observed among women with SSD were peculiar. The average daily intake of sugars and the amount of sugar required to sweeten the bitter drink were significantly higher among women with SSD (p 0.02). Conclusion: There are more women with SSD between stressed, and consumption of sugars and behaviors related to the search for sweets are distinct from women without DSD, as well as tolerance to the bitter taste. References [1] LIPP, M. N. Invent´ ario de Sintomas de Estresse para Adultos de Lipp. S˜ ao Paulo: Casa do Psic´ ologo, 2000. Disclosure of Interest: None Declared

LB022-SUN MICRONUTRIENT STATUS IN IBD PATIENTS M. Plas1 , M. van den Berg2 , W. Mares3 , B. Witteman3 , J. Klein Gunnewiek4 , J. de Vries5 . 1 Nutrition Alliance, Hospital Gelderse Vallei, EDE, 2 Human Nutrition, Wageningen University, Wageningen, 3 Internal Medicine, 4 Laboratory, Hospital Gelderse Vallei, 5 Human Nutrition, Wageningen University, EDE, Netherlands Rationale: Inflammatory bowel diseases (IBD) including Crohn’s disease and Ulcerative Colitis can lead to malnutrition by decreased dietary intake and nutrient malabsorption. The aim of the study was to investigate the prevalence of IBD-patients at risk of malnutrition including micronutrient deficiencies. Methods: Of the 41 patients recruited from the outpatient clinic, 22 had ulcerative colitis and 19 Crohn’s disease. Risk of malnutrition was assessed according to the Malnutrition Universal Screening Tool (MUST). In addition, hand grip strength (HGS) and data on serum micronutrient values (vitamins B1, B6, B12, D, E, folic acid, calcium, selenium, magnesium) were collected. Finally, patients filled out a food frequency questionnaire (FFQ) to assess micronutrient intakes. A one sample t-test was used to compare serum values, micronutrient intakes

259 and HGS with their age and gender specific reference values. Results: According to the MUST 4 patients were at risk of malnutrition. Nine patients had a lower HGS than their age and gender specific reference value. Mean serum vitamin D (61.3 nmol/l), folic acid (22.1 nmol/l), calcium (2.37 nmol/l), selenium (1.03 mmol/l), and magnesium (0.85 nmol/l) levels were significantly below their respective mean reference values (p < 0.05). Patients with active disease seemed to have a lower calcium level and a higher folic acid level. Other results were not influenced by activity index. Of these micronutrients, mean intakes of folic acid 191.0 mg/day) and vitamin D (4.0 mg/day) were inadequate in comparison to the Estimated Average Requirements. Conclusion: Our study shows that IBD outpatients may be at risk of malnutrition, including deficiencies of micronutrients. For some micronutrients this may be explained by an inadequate intake. Disclosure of Interest: None Declared

LB023-SUN A NON-RANDOMIZED COMPARISON OF TUBE FEEDING OF ELEMENTAL DIET AND LOW RESIDUE DIET IN HEAD AND NECK CANCER PATIENTS DURING CONCURRENT CHEMORADIOTHERAPY Y. Yajima1 , T. Kobayashi1 , H. Ishiki1 , S. Kobayashi2 , S. Suzuki2 , R. Hayashi3 , T. Akimoto4 , M. Tahara1 . 1 Head and Neck Medical Oncology, 2 Pharmacology, 3 Head and Neck Surgery, 4 Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Japan Rationale: Oral mucositis is one of the most critical but unavoidable adverse events among head and neck cancer patients during concurrent chemoradiotherapy. Prophylactic percutaneous endoscopic gastrostomy (PEG) is well known supportive care to keep nutritional condition better for those patients but no nutrient has been proved to be more favorable than others. Here we investigated our patients if there are different effects on oral mucositis between those who nourished by low residue diet (LRD) and by elemental diet (ED), focusing on the glutamine, which is effective to prevent infection and repair mucous injury, and is contained only in the latter. Methods: This is a retrospective, non-randomized comparison. The patients were locally advanced head and neck cancer who had started definite chemoradiotherapy between 1st July and 31st December 2011, with PEG in advance. They were stratified into two groups according to the kinds of nutrients given, LRD and ED respectively. The primary endpoint was the incidence of infection during the therapy and secondary endpoints were severity of oral mucositis, other adverse effects and body weight loss. Adverse effects were assessed by CTCAE version 4.0. The statistical differences were analyzed by Fisher’s exact test and Mann-Whitney U-test. Results: The total number of the patients included in the analysis was 34, divided into two groups one with LRD nourished (n = 20) and the other with ED (n = 14). The incidence of infection was 30% in LRD group and 7.1% in ED