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Lead concentration in different organs of seagulls from Northwest of Spain
S206
Abstracts / Toxicology Letters 258S (2016) S62–S324
Apparently the above observations and hypothesis require further investigation. http://dx.doi.org/10.1016/j.toxlet.2016.06.1748 P12-003 Lead concentration in different organs of seagulls from Northwest of Spain S. Martinez Morcillo 1,∗ , J. Vizuete 1 , A. Lopez Beceiro 2 , L. Fidalgo 2 , M. Perez Lopez 1 , D. Hernandez Moreno 1 , M. Miguez 1 1
Unit of Toxicology, Faculty of Veterinary (University of Extremadura), Cáceres, Spain 2 Department of Clinical Veterinary Sciences, Faculty of Veterinary (University of Santiago de Compotela), Lugo, Spain
The environment is exposed to different pollutants, being lead (Pb) one of the most commonly detected metal in contaminated ecosystems, mainly associated to different anthropogenic sources (industry, gasoline, agriculture). Seabirds have often played an important role as bioindicators of environmental pollution because they are exposed to a wide range of chemicals (mainly by food and water exposure) since they are top predators and scavengers. Moreover, in many places seagulls are considered pests and there are intensive control plans to reduce their numbers, thus providing a large number of environmental samples of great interest. The main objective of this study was to determine Pb concentrations in soft organs (liver and kidney) of seagulls from NW of Spain. For this purpose, 20 seagulls Larus michahellis were sampled during campaigns for population control in NW Spain, and the Pb content was determined by ICP-MS. Animals were divided according to gender, age (young and adults) and sampling area (Atlantic and Cantabric area). The results showed that hepatic Pb concentrations were significantly lower than renal ones (0.664 ± 0.385 and 5.111 ± 3.940 mg/kg, respectively). Males showed significantly higher Pb concentrations than females in both considered organs. Moreover, adult gulls had greater values of Pb than young did in both tissues; which could be associated to Pb partially accumulated as toxicologically inactive complexes with metallothionein. In relation to the sampling area, animals from the Cantabric area had greater Pb content than those from the Atlantic, being this difference specially significant in kidney. http://dx.doi.org/10.1016/j.toxlet.2016.06.1749 P12-004 Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study ´ ´ cic´ 1 , L. Lazarevic´ 1 , D. D. Ðukic´ Cosi c´ 1 , E. Antonijevic´ 1 , M. Curˇ Jorgovanovic´ 1 , M. Vidosavljevic´ 1 , S. Jankovic´ 2 , Z. Bulat 1 , A. Buha 1 , V. Matovic´ 1,∗ , B. Antonijevic´ 1 1
Department of Toxicology “Akademik Danilo Soldatovi´c”, University of Belgrade – Faculty of Pharmacy, Belgrade, Serbia 2 Institute of Meat Hygiene and Technology, Belgrade, Serbia
Mercury (Hg) enters the food chain as methyl-mercury (MeHg) and the major sources of intake of this toxic chemical for all age groups are fish and fish products. Being rich in essential nutrients such as omega fatty acids, these dietary products are of special concern for children. However, MeHg has a harmful impact on brain development, especially in infants and children. The aim of
this pilot study was to assess Hg intake via fish and fish products in children of Belgrade, Serbia. Data on Hg concentration in fish and fish products have been obtained from the Institute of Meat Hygiene and Technology, Belgrade. Data on body weight at the individual level, species of consumed fish and fish products, frequency and amount of consumption were obtained by questionnaire for parents of 49 children. A probabilistic assessment approach was applied for data integration using Monte Carlo simulation (100 iterations) in the @RISK software. The calculated results showed that the total exposure distribution to mercury ranged from 0.0018 g/kg bw/day at the 5th percentile, 0.0276 g/kg bw/day at the 50th percentile to 0.2642 g/kg bw/day at the 95th percentile. These results indicate that a certain number of investigated children (4%) are exposed to Hg concentrations exceeding the level proposed by EPA −0.1 g Hg/kg bw/day. Parents should pay more attention to the quantity and frequency of fish and fish products consumption and thus provide favorable health effects of these products and avoid increased risk for their childrens health. (Projects: III 46009, 451-03-3095/2014-09/03). http://dx.doi.org/10.1016/j.toxlet.2016.06.1750 P12-005 The association with human biomonitoring and the sources of cadmium exposure among the general Korean adults M. Hwang ∗ , J. Park, A. Ko, Y. Kho, I. Hwang Cadmium is a heavy metal found in nature, and as an environmental contaminant resulting from industrial activities that has been associated with adverse health effects including increased risk of cancers, skeletal damage, and kidney dysfunction. This study examined the association with blood cadmium levels (B-Cd) or urinary cadmium levels (U-Cd) and the sources of cadmium exposure among the general Korean adults aged 19–64. There was a significant difference of B-Cd or U-Cd between men and women. In men, age and smoking status were associated with B-Cd and U-Cd. Alcohol consumption was only associated with B-Cd, and BMI was only associated with U-Cd (creatinine pre adjusted). In women, age was only associated with B-Cd or U-Cd. Smoking status was only associated with B-Cd. Although food intake is the main source of cadmium exposure, there was no association with B-Cd or U-Cd except the association between B-Cd and seaweeds consumption in women. Overall, although there were many limitations to explain cadmium exposure, B-Cd reflect correlation with the sources of cadmium exposure more than U-Cd. The comparison of reported B-Cd or U-Cd among different countries revealed that exposures in Korea were 3–4 times higher than other countries. In the ratio between B-Cd or U-Cd and food intake, results (B-Cd/food intake 6.18, U-Cd/food intake 5.71) were over 3–7 times higher than other countries. Thus, more studies are required to explain why B-Cd or U-Cd of the Korean population is higher than that of other countries. http://dx.doi.org/10.1016/j.toxlet.2016.06.1751
Abstracts / Toxicology Letters 258S (2016) S62–S324
Apparently the above observations and hypothesis require further investigation. http://dx.doi.org/10.1016/j.toxlet.2016.06.1748 P12-003 Lead concentration in different organs of seagulls from Northwest of Spain S. Martinez Morcillo 1,∗ , J. Vizuete 1 , A. Lopez Beceiro 2 , L. Fidalgo 2 , M. Perez Lopez 1 , D. Hernandez Moreno 1 , M. Miguez 1 1
Unit of Toxicology, Faculty of Veterinary (University of Extremadura), Cáceres, Spain 2 Department of Clinical Veterinary Sciences, Faculty of Veterinary (University of Santiago de Compotela), Lugo, Spain
The environment is exposed to different pollutants, being lead (Pb) one of the most commonly detected metal in contaminated ecosystems, mainly associated to different anthropogenic sources (industry, gasoline, agriculture). Seabirds have often played an important role as bioindicators of environmental pollution because they are exposed to a wide range of chemicals (mainly by food and water exposure) since they are top predators and scavengers. Moreover, in many places seagulls are considered pests and there are intensive control plans to reduce their numbers, thus providing a large number of environmental samples of great interest. The main objective of this study was to determine Pb concentrations in soft organs (liver and kidney) of seagulls from NW of Spain. For this purpose, 20 seagulls Larus michahellis were sampled during campaigns for population control in NW Spain, and the Pb content was determined by ICP-MS. Animals were divided according to gender, age (young and adults) and sampling area (Atlantic and Cantabric area). The results showed that hepatic Pb concentrations were significantly lower than renal ones (0.664 ± 0.385 and 5.111 ± 3.940 mg/kg, respectively). Males showed significantly higher Pb concentrations than females in both considered organs. Moreover, adult gulls had greater values of Pb than young did in both tissues; which could be associated to Pb partially accumulated as toxicologically inactive complexes with metallothionein. In relation to the sampling area, animals from the Cantabric area had greater Pb content than those from the Atlantic, being this difference specially significant in kidney. http://dx.doi.org/10.1016/j.toxlet.2016.06.1749 P12-004 Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study ´ ´ cic´ 1 , L. Lazarevic´ 1 , D. D. Ðukic´ Cosi c´ 1 , E. Antonijevic´ 1 , M. Curˇ Jorgovanovic´ 1 , M. Vidosavljevic´ 1 , S. Jankovic´ 2 , Z. Bulat 1 , A. Buha 1 , V. Matovic´ 1,∗ , B. Antonijevic´ 1 1
Department of Toxicology “Akademik Danilo Soldatovi´c”, University of Belgrade – Faculty of Pharmacy, Belgrade, Serbia 2 Institute of Meat Hygiene and Technology, Belgrade, Serbia
Mercury (Hg) enters the food chain as methyl-mercury (MeHg) and the major sources of intake of this toxic chemical for all age groups are fish and fish products. Being rich in essential nutrients such as omega fatty acids, these dietary products are of special concern for children. However, MeHg has a harmful impact on brain development, especially in infants and children. The aim of
this pilot study was to assess Hg intake via fish and fish products in children of Belgrade, Serbia. Data on Hg concentration in fish and fish products have been obtained from the Institute of Meat Hygiene and Technology, Belgrade. Data on body weight at the individual level, species of consumed fish and fish products, frequency and amount of consumption were obtained by questionnaire for parents of 49 children. A probabilistic assessment approach was applied for data integration using Monte Carlo simulation (100 iterations) in the @RISK software. The calculated results showed that the total exposure distribution to mercury ranged from 0.0018 g/kg bw/day at the 5th percentile, 0.0276 g/kg bw/day at the 50th percentile to 0.2642 g/kg bw/day at the 95th percentile. These results indicate that a certain number of investigated children (4%) are exposed to Hg concentrations exceeding the level proposed by EPA −0.1 g Hg/kg bw/day. Parents should pay more attention to the quantity and frequency of fish and fish products consumption and thus provide favorable health effects of these products and avoid increased risk for their childrens health. (Projects: III 46009, 451-03-3095/2014-09/03). http://dx.doi.org/10.1016/j.toxlet.2016.06.1750 P12-005 The association with human biomonitoring and the sources of cadmium exposure among the general Korean adults M. Hwang ∗ , J. Park, A. Ko, Y. Kho, I. Hwang Cadmium is a heavy metal found in nature, and as an environmental contaminant resulting from industrial activities that has been associated with adverse health effects including increased risk of cancers, skeletal damage, and kidney dysfunction. This study examined the association with blood cadmium levels (B-Cd) or urinary cadmium levels (U-Cd) and the sources of cadmium exposure among the general Korean adults aged 19–64. There was a significant difference of B-Cd or U-Cd between men and women. In men, age and smoking status were associated with B-Cd and U-Cd. Alcohol consumption was only associated with B-Cd, and BMI was only associated with U-Cd (creatinine pre adjusted). In women, age was only associated with B-Cd or U-Cd. Smoking status was only associated with B-Cd. Although food intake is the main source of cadmium exposure, there was no association with B-Cd or U-Cd except the association between B-Cd and seaweeds consumption in women. Overall, although there were many limitations to explain cadmium exposure, B-Cd reflect correlation with the sources of cadmium exposure more than U-Cd. The comparison of reported B-Cd or U-Cd among different countries revealed that exposures in Korea were 3–4 times higher than other countries. In the ratio between B-Cd or U-Cd and food intake, results (B-Cd/food intake 6.18, U-Cd/food intake 5.71) were over 3–7 times higher than other countries. Thus, more studies are required to explain why B-Cd or U-Cd of the Korean population is higher than that of other countries. http://dx.doi.org/10.1016/j.toxlet.2016.06.1751