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Leading causes of death in the liver transplant population compared to the corresponding age-matched general US population
Leading Causes of Death in the Liver Transplant Population Compared to the Corresponding Age-Matched General US Population E. Molmenti, D. Casey, L. Jennings, H. Molmenti, G. Jung, S. Marubashi, E. Sanchez, R. Goldstein, M. Levy, C. Fasola, T. Gonwa and G. Klintmalm
W
E SOUGHT to compare the causes of death in the liver transplant (OLTx) and general nontransplant populations.
MATERIAL AND METHODS We analyzed the database maintained at our institution for 1554 patients transplanted between December 1984 and December 1999. The primary cause of death was taken into consideration. Data for the general population was obtained from the National Vital Statistics System for 1997. Seven major categories were chosen for comparison. Deaths from motor vehicle accidents, homicides, etc. were grouped under “other.” Table 1 lists our results.
CONCLUSIONS
Cerebrovascular accidents and pulmonary causes of death were seen with a higher frequency in the general population in the 65⫹ age group. Transplant recipients had a higher incidence of deaths from infectious, liver/allograft, and renal complications at all ages. From the Baylor University Medical Center, Dallas, Texas, USA. Address reprint requests to Dr E. Molmenti, Baylor University Medical Center, Transplantation Services, 4th Floor, 3500 Gaston Ave, Dallas, TX 75246.
Table 1. Results Age Group (y)
25– 44
45– 64
65⫹
Population
Transplant
General
Transplant
General
Transplant
General
Cardiovascular Cerebrovascular Liver failure Infection Malignancy Renal Pulmonary Other
6.0 3.4 33.3 23.1 12.0 0.9 — 21.3
12.2 2.6 3.0 9.6 16.1 — — 56.5
19.2 4.6 21.8 22.8 15.0 2.3 2.0 12.3
27.0 4.1 2.9 2.8 35.0 — 3.4 24.8
18.0 3.3 13.1 18.0 29.5 8.2 1.6 8.3
35.1 8.1 — 5.5 22.1 1.3 5.5 22.4
© 2001 by Elsevier Science Inc. 655 Avenue of the Americas, New York, NY 10010
0041-1345/01/$–see front matter PII S0041-1345(00)02820-7 1531
Transplantation Proceedings, 33, 1531 (2001)
W
E SOUGHT to compare the causes of death in the liver transplant (OLTx) and general nontransplant populations.
MATERIAL AND METHODS We analyzed the database maintained at our institution for 1554 patients transplanted between December 1984 and December 1999. The primary cause of death was taken into consideration. Data for the general population was obtained from the National Vital Statistics System for 1997. Seven major categories were chosen for comparison. Deaths from motor vehicle accidents, homicides, etc. were grouped under “other.” Table 1 lists our results.
CONCLUSIONS
Cerebrovascular accidents and pulmonary causes of death were seen with a higher frequency in the general population in the 65⫹ age group. Transplant recipients had a higher incidence of deaths from infectious, liver/allograft, and renal complications at all ages. From the Baylor University Medical Center, Dallas, Texas, USA. Address reprint requests to Dr E. Molmenti, Baylor University Medical Center, Transplantation Services, 4th Floor, 3500 Gaston Ave, Dallas, TX 75246.
Table 1. Results Age Group (y)
25– 44
45– 64
65⫹
Population
Transplant
General
Transplant
General
Transplant
General
Cardiovascular Cerebrovascular Liver failure Infection Malignancy Renal Pulmonary Other
6.0 3.4 33.3 23.1 12.0 0.9 — 21.3
12.2 2.6 3.0 9.6 16.1 — — 56.5
19.2 4.6 21.8 22.8 15.0 2.3 2.0 12.3
27.0 4.1 2.9 2.8 35.0 — 3.4 24.8
18.0 3.3 13.1 18.0 29.5 8.2 1.6 8.3
35.1 8.1 — 5.5 22.1 1.3 5.5 22.4
© 2001 by Elsevier Science Inc. 655 Avenue of the Americas, New York, NY 10010
0041-1345/01/$–see front matter PII S0041-1345(00)02820-7 1531
Transplantation Proceedings, 33, 1531 (2001)