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Leukoaraiosis as a predictor of pneumonia after acute ischemic stroke
ORAL SESSION
885
O1-2-6 Leukoaraiosis as a predictor of pneumonia after acute ischemic stroke Ki-Woong Nam
Department of Neurology, Seoul National
University Hospital, Republic of Korea.
Hyung-Min Kwon,1 Jae-Sung Lim,2 and Yong-Seok Lee1 1 Department of Neurology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Republic of Korea 2 Department of Neurology, Hallym University Sacred Heart Hospital, Republic of Korea
【Background and Purpose】Stroke-associated pneumonia (SAP) is common in patients with acute ischemic stroke, and several risk factors have been reported. However, the relationship between underlying leukoaraiosis (LA) and SAP has not been addressed. 【Methods】We recruited consecutive patients with acute ischemic stroke within 24 hours of symptom onset. SAP was defined as (1) a new-onset auscultatory crackle on the lung fields with a fever of 37.7°C or higher, (2) definite radiological findings of pneumonia, or (3) newonset or aggravated purulent sputum. LA was graded using the Fazekas scale in both the periventricular and subcortical areas. We evaluated LA burden by summing the grade and dichotomized into mild LA (0-2) or severe LA (3-6). Relationship between LA and SAP was analyzed by binary logistic regression analysis with variables of P < .05 in bivariable analysis. 【Results】308 consecutive patients were enrolled, and SAP developed in 36 patients (12%). Bivariate analysis revealed that SAP correlated with age, initial NIHSS score, fasting blood sugar, atrial fibrillation, impaired consciousness, dysphagia, severe LA, body mass index, lowdensity lipoprotein cholesterol (LDL-C), albumin, and hyperlipidemia. Severe LA [adjusted OR (aOR) = 5.33, 95% CI = 1.69-16.85, P < .01], dysphagia [aOR = 4.60, 95% CI = 1.31-16.13, P = .02] and lower LDL-C levels [aOR = .98, 95% CI = .97-1.00.11, P = .02] remained independent predictors of SAP in multivariable analysis. 【Conclusions】Underlying severe LA is an independent predictor of SAP in acute ischemic stroke. Careful observation of these high risk patients is mandatory.
O1-2-7 Prevalence of complete internal carotid artery occlusion in Persian stroke population Fariba Yadolahi
Physical Therapy Department, School of
Rehabilitation, Shahid Beheshti University of Medical Sciences, Iran.
Masoud Mehrpour Department of Neurology, Faculty of Medicine, Iran University of Medical Sciences, Iran
【Background】Stroke is the main cause of disability among the adults around the world which. The annual incidence of first ever stroke among the Iranian population which is significantly higher than in most western countries and also occurs at lower age ranges. The most common cause of ischemic stroke is atherosclerotic stenosis of the major intracranial arteries. 【Objective】We aimed to investigate the Prevalence of Internal Carotid Complete Occlusion among Iranian Population. 【Methods】In this population based study 1033 patients with ischemic stroke who admitted in referral stroke unit center enrolled. TCCS was performed for all of them and ICA complete occlusions was confirmed with using cerebral angiography. 【Results】Among 1033 subjects, 75 have ICA complete occlusions (7.26%).52 patients were male (69.3%) and 23 patients were female (30.7%). 【Conclusion】To our knowledge This is the first study defined prevalence of ICA complete occlusions in the Iran. In our center was 7.26% and rate of ICA complete occlusions in Male was higher than female.
O1-2-8 Prevalence of vertebral artery atherosclerotic changes in healthy heavy smokers: A population-based study Fariba Yadolahi
Physical Therapy Department, School of
Rehabilitation, Shahid Beheshti University of Medical Sciences, Iran.
Masoud Mehrpour Department of Neurology, Faculty of Medicine, Iran University of Medical Sciences, Iran
【Background】Cigarette smoking seems to contribute to progression of atherosclerosis in vertebral artery. The aim of this study was to investigate the prevalence of asymptomatic vertebral artery stenosis and potential risk of cigarette smoking in healthy volunteers. 【Methods】200 healthy volunteers on the basis of inclusion and exclusion criteria were studies. Among 200 healthy volunteers,17 heavy smoker cases were found. 68 healthy non-smoker controls (fourfold) were randomly chose among 183 remained samples. All subjects underwent vertebral artery Color-Duplex Ultrasonography. For comparison of two groups we provided Odds Ratio of logistic regression by Stata software. 【Results】The mean age of participants was 42.8. The mean arterial diameter of proximal vertebral artery for right side in case was 4.31 (SD .75) and for left side was 4.36 (SD .66). The diameter for control groups in right and left sides were 4.23 (SD .79) and 4.18 (SD .70), respectively. The mean peak systolic velocity in cases was
885
O1-2-6 Leukoaraiosis as a predictor of pneumonia after acute ischemic stroke Ki-Woong Nam
Department of Neurology, Seoul National
University Hospital, Republic of Korea.
Hyung-Min Kwon,1 Jae-Sung Lim,2 and Yong-Seok Lee1 1 Department of Neurology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Republic of Korea 2 Department of Neurology, Hallym University Sacred Heart Hospital, Republic of Korea
【Background and Purpose】Stroke-associated pneumonia (SAP) is common in patients with acute ischemic stroke, and several risk factors have been reported. However, the relationship between underlying leukoaraiosis (LA) and SAP has not been addressed. 【Methods】We recruited consecutive patients with acute ischemic stroke within 24 hours of symptom onset. SAP was defined as (1) a new-onset auscultatory crackle on the lung fields with a fever of 37.7°C or higher, (2) definite radiological findings of pneumonia, or (3) newonset or aggravated purulent sputum. LA was graded using the Fazekas scale in both the periventricular and subcortical areas. We evaluated LA burden by summing the grade and dichotomized into mild LA (0-2) or severe LA (3-6). Relationship between LA and SAP was analyzed by binary logistic regression analysis with variables of P < .05 in bivariable analysis. 【Results】308 consecutive patients were enrolled, and SAP developed in 36 patients (12%). Bivariate analysis revealed that SAP correlated with age, initial NIHSS score, fasting blood sugar, atrial fibrillation, impaired consciousness, dysphagia, severe LA, body mass index, lowdensity lipoprotein cholesterol (LDL-C), albumin, and hyperlipidemia. Severe LA [adjusted OR (aOR) = 5.33, 95% CI = 1.69-16.85, P < .01], dysphagia [aOR = 4.60, 95% CI = 1.31-16.13, P = .02] and lower LDL-C levels [aOR = .98, 95% CI = .97-1.00.11, P = .02] remained independent predictors of SAP in multivariable analysis. 【Conclusions】Underlying severe LA is an independent predictor of SAP in acute ischemic stroke. Careful observation of these high risk patients is mandatory.
O1-2-7 Prevalence of complete internal carotid artery occlusion in Persian stroke population Fariba Yadolahi
Physical Therapy Department, School of
Rehabilitation, Shahid Beheshti University of Medical Sciences, Iran.
Masoud Mehrpour Department of Neurology, Faculty of Medicine, Iran University of Medical Sciences, Iran
【Background】Stroke is the main cause of disability among the adults around the world which. The annual incidence of first ever stroke among the Iranian population which is significantly higher than in most western countries and also occurs at lower age ranges. The most common cause of ischemic stroke is atherosclerotic stenosis of the major intracranial arteries. 【Objective】We aimed to investigate the Prevalence of Internal Carotid Complete Occlusion among Iranian Population. 【Methods】In this population based study 1033 patients with ischemic stroke who admitted in referral stroke unit center enrolled. TCCS was performed for all of them and ICA complete occlusions was confirmed with using cerebral angiography. 【Results】Among 1033 subjects, 75 have ICA complete occlusions (7.26%).52 patients were male (69.3%) and 23 patients were female (30.7%). 【Conclusion】To our knowledge This is the first study defined prevalence of ICA complete occlusions in the Iran. In our center was 7.26% and rate of ICA complete occlusions in Male was higher than female.
O1-2-8 Prevalence of vertebral artery atherosclerotic changes in healthy heavy smokers: A population-based study Fariba Yadolahi
Physical Therapy Department, School of
Rehabilitation, Shahid Beheshti University of Medical Sciences, Iran.
Masoud Mehrpour Department of Neurology, Faculty of Medicine, Iran University of Medical Sciences, Iran
【Background】Cigarette smoking seems to contribute to progression of atherosclerosis in vertebral artery. The aim of this study was to investigate the prevalence of asymptomatic vertebral artery stenosis and potential risk of cigarette smoking in healthy volunteers. 【Methods】200 healthy volunteers on the basis of inclusion and exclusion criteria were studies. Among 200 healthy volunteers,17 heavy smoker cases were found. 68 healthy non-smoker controls (fourfold) were randomly chose among 183 remained samples. All subjects underwent vertebral artery Color-Duplex Ultrasonography. For comparison of two groups we provided Odds Ratio of logistic regression by Stata software. 【Results】The mean age of participants was 42.8. The mean arterial diameter of proximal vertebral artery for right side in case was 4.31 (SD .75) and for left side was 4.36 (SD .66). The diameter for control groups in right and left sides were 4.23 (SD .79) and 4.18 (SD .70), respectively. The mean peak systolic velocity in cases was