ABSTRACTS
898 Postradiation
Bone Sarcoma.
January-February,
OF
CTJRRENT
0. s., 0. iv., & 0. P.
LITERATlJRE
August,
M. Cruz, B. II. Coley, and F. W. Stewart.
1957
Cancer 10: 80,
1957.
In a series of eleven bone sarcoma, one patient mucosa.
cases (seven had a primary
men and diagnosis
four women) of epidermoid
diagnosed carcinoma
as postradiation of the buceal
The patient, a 52-year-old white man, was treated first with radium in 1934. In 1936 he received roentgen-ray therapy because of sequestration and draining sinus formation. He was seen in 1942 with trismus, abscess formation, and a necrotic, ulcerated exeaA biopsy vation of the right cheek at the site of the previous radium implantation. showed chronic inflammatory and necrotic tissue. Antibiotic therapy was used with good results. When he was seen again in 1951, examination disclosed a 1.5 by 3 cm. hard, tender, granular mass between the alveolar process and the angle of the mandible. A radical excision of the right mandible was done and the pathologic diagnosis was osteogenic sarcoma. The patient died nine months after the resection. T. J. C.
The Natural History and Effects of Treatment of Cancer of the Tongue. and M. J. Healy. Cancer 9: 842, November-December, 1956. Of a positive
168 cases serology.
Fifty-eight tongue. All were grades to metastasize. squamous-cell The sion,
total
studiel, Thirteen
16 per cent had a history patients had symptoms
per cent of the tumors tumors were epidermoid II and III. Tumors in the More than 10 per cent carcinoma. five-year
cure
rate
was
13.4
since 61.2 per cent into the difficult-to-treat
of being treated for syphilis more than one year.
involved both or squamous-cell middle third of of the patients
the
It is felt that these cases fell
for
per
of
M. K. DuVal,
Jr.,
or had
the
floor of the mouth and the carcinomas and 95 per cent the tongue showed less tendency developed a secondary primary
cent.
the patients group.
had
cervical
metastases
on
admisT. J. C.
Leukoplakia
of the Renal
J. Ural.
76:
330,
Pelvis
and the Bladder.
B. S. Abeshouse
and L. H. Tankin.
1956.
The authors present a brief review of cases of leukoplakia of the renal pelvis and bladder. Approximately 100 cases have been reported. Involvement of the bladder by this lesion is three times as frequent as involvement of the renal pelvis and about twenty times as frequent as involvement of the ureter. Leukoplakia of the bladder is most commonly observed in women. The etiology of this condition has not been established, but the following theories have been proposed: infection, irritation, dietary deficiency (vitamin A), embryologic defects, and hormonal imbalance. The essential pathologic change is replacement of the normal transitional epithelium by a cornified squamous epithelium. On cystoscopic examination, one finds areas of whitish gray or pearllike plaques. The diagnosis of leukoplakia of the renal pelvis cases have been correctly diagnosed preoperatively. the urine are pathognomonic of the lesion, as is the calyces on retrograde pyelography. The lihood of infection of treatment tion, and
therapy for leukoplakia of the malignant change. In cases of is advised. The treeatment of of the infection, both locally the administration of cortisone
is extremely difficult, and However, flakes of gritty mottled appearance of the
only three tissue in pelvis and
renal pelvis is nephrectomy, because of the likebilateral renal disease vigorous treatment of the leukoplakia of the bladder is varied and consists and systemically, high vitamin A diet, fulguraand BCTH. T. J. C.