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Lipoatrophic panniculitis
Posters
- Miscellnneoics
biological tests were negative. The rectocolon-sigmoidoscopy showed that the mucosa presented no inflammatory pathologies. A bioptical examination of the labium maius pudendi showed chronic, denno-hypodermic inflammation with nodular granulomas containing epitelioid and giant cells without caseification. On the basis of the clinical and histological picture, a Crohn disease has been defined, followed by treatment with 5-methylprednisolone and metronidazole. After few weeks, a noteworthy improvement of the clinical situation was observed. This case-report is interesting for the rarity of the prim‘ary vulvar localisation, which sometimes may anticipate of some years the bowel symptomatology or represent the unique expression of the disease. References [I] Urbanek M., Neil SM., McKee P.M.: Clin Exp Dermat 21: 21 l-214, 1996 panniculitis I P287 Lipoatrophic L.M. Torres, N. Diez-Caballero, S. Honorato, C. Schoendorff, C. Garcia, S. Urrutia, D. Garcia Almagro. Hospital Virgerr de Salud,
Toledo,
kc
Spaitl
We present the case of a 23 year old woman, diagnosed one year ago as a case of primary hypothyroidism, who presented predominantly distal lesions on the extremities which gave rise to the loss of subcutaneous cell tissue, this picture being compatible with the diagnosis of lipoattophic paniculitis.
P289 iI
s253
A case of eosinophilic Ofuji
pustular
V. Petronic-Rosic. S. Vesic, M. Milojevid, 0. CvijetiC. of Dermatovenereology,
Belgrade,
Acrokeratosis A case report
paraneoplastica
Bazex:
V. Petronfc-RosiE, M. Milojevic. S. VesiC. Institute Derrnatovenereology,
Belgmde,
of
hgoslnvia
A 56-year-old Caucasian man presented with all the clinical features of acrokeratosis paraneoplastica of Bazex. He showed the characteristic violeceus erythema and scaling of the nose, the aural helices and periungual regions with severe nail dystrophy. Extensive investigations failed to reveal any associated malignancy up to 8 months after the onset of the skin eruption. While the skin was improving with topical steroids, and although the patient was still asymptomatic, evidence of metastatic squamous cell carcinoma of the cervical region was obtained. A continuing search for the primary neoplasm was unproductive until I7 months after initial presentation when a tumor of the floor of the oral cavity was discovered. The patient denied tmther diagnostic or therapeutic procedures. Despite clinical improvement of the skin lesions, his physical status began to decline and he died 23 months after the onset of paraneoplastic acrokeratosis. The bizarre clinical aspects of the syndrome are reviewed.
of
Institute
Yugoslavia
A 38-year-old Caucasian female presented with a pruritic pustular eruption of the frontal scalp of 7 days duration. A 8 x 5 cm well defined erythematous plaque studded with follicular pustules was noted in the anterior parietal region. Laboratory tests were within normal values. Skin swabs yielded Streptococcus alpha hemolyticus and Staphylococcus aureus. Topical and systemic antibiotics were of no avail. New, now sterile pustules, continued to appear. Histopathologic analysis of a skin biopsy specimen confirmed the diagnosis of eosinophilic pustular folliculitis. Direct immunofluorescence tests was negative; the eosinophil count in a chamber was 44/mm3 of blood. The eruption persisted despite the administration of dapson (100 mg/d). dexamethason (3 mg/d) and diklofenak-sodium (100 mg/d). Indometacin (75 mg/d) led to complete remission within 5 weeks but failed to control periodic recurrences during the following year, as did diverse topical and oral medications. Systemic PUVA therapy (IO J/cm?) led to partial clearance of the skin lesions and pruritus in 3 weeks. Our patient is particularly interesting due to the fact that she is a Caucasian female with Ofuji’s folliculitis localized to the scalp and resistant to various treatment modalities. I P290
The factors that promote ruber planus in Estonia
developing
H. Silm, S. Kaur, M. Karelson, K. Kingo. I P288
folliculitis
Dematology
Tartu
University,
Department
lichen of
Estonia
Lichen ruber planus (LP) accounts for about 0.7-0.8 per cent of dermatological outpatients in Britain and Nortb America. The same could be said about the situation in Estonia. During big changes in our economic, social and political life after 1991 the incidence of LP increased (2-38). There is considerable evidence that underlying processes involved in the pathogenesis of LP are immunologicaJly mediated. The aim of this paper is to investigate the factors promoting the development of LP in Estonia. We analysed 108 cases of LP treated at the Clinic of Dermatology of Tartu University in 1993-1997. On the basis of our investigation we can draw the conclusion that (a) stress may be considered the most important factor promoting the development of LP (b) LP was contracted more Frequently by patients who were suffering from diabetes mellitus. (c) All our patients with LP had had different tumors in their family histories. (d) The results of our research should be considered in carrying out adequate treatment according to promoting factors.
- Miscellnneoics
biological tests were negative. The rectocolon-sigmoidoscopy showed that the mucosa presented no inflammatory pathologies. A bioptical examination of the labium maius pudendi showed chronic, denno-hypodermic inflammation with nodular granulomas containing epitelioid and giant cells without caseification. On the basis of the clinical and histological picture, a Crohn disease has been defined, followed by treatment with 5-methylprednisolone and metronidazole. After few weeks, a noteworthy improvement of the clinical situation was observed. This case-report is interesting for the rarity of the prim‘ary vulvar localisation, which sometimes may anticipate of some years the bowel symptomatology or represent the unique expression of the disease. References [I] Urbanek M., Neil SM., McKee P.M.: Clin Exp Dermat 21: 21 l-214, 1996 panniculitis I P287 Lipoatrophic L.M. Torres, N. Diez-Caballero, S. Honorato, C. Schoendorff, C. Garcia, S. Urrutia, D. Garcia Almagro. Hospital Virgerr de Salud,
Toledo,
kc
Spaitl
We present the case of a 23 year old woman, diagnosed one year ago as a case of primary hypothyroidism, who presented predominantly distal lesions on the extremities which gave rise to the loss of subcutaneous cell tissue, this picture being compatible with the diagnosis of lipoattophic paniculitis.
P289 iI
s253
A case of eosinophilic Ofuji
pustular
V. Petronic-Rosic. S. Vesic, M. Milojevid, 0. CvijetiC. of Dermatovenereology,
Belgrade,
Acrokeratosis A case report
paraneoplastica
Bazex:
V. Petronfc-RosiE, M. Milojevic. S. VesiC. Institute Derrnatovenereology,
Belgmde,
of
hgoslnvia
A 56-year-old Caucasian man presented with all the clinical features of acrokeratosis paraneoplastica of Bazex. He showed the characteristic violeceus erythema and scaling of the nose, the aural helices and periungual regions with severe nail dystrophy. Extensive investigations failed to reveal any associated malignancy up to 8 months after the onset of the skin eruption. While the skin was improving with topical steroids, and although the patient was still asymptomatic, evidence of metastatic squamous cell carcinoma of the cervical region was obtained. A continuing search for the primary neoplasm was unproductive until I7 months after initial presentation when a tumor of the floor of the oral cavity was discovered. The patient denied tmther diagnostic or therapeutic procedures. Despite clinical improvement of the skin lesions, his physical status began to decline and he died 23 months after the onset of paraneoplastic acrokeratosis. The bizarre clinical aspects of the syndrome are reviewed.
of
Institute
Yugoslavia
A 38-year-old Caucasian female presented with a pruritic pustular eruption of the frontal scalp of 7 days duration. A 8 x 5 cm well defined erythematous plaque studded with follicular pustules was noted in the anterior parietal region. Laboratory tests were within normal values. Skin swabs yielded Streptococcus alpha hemolyticus and Staphylococcus aureus. Topical and systemic antibiotics were of no avail. New, now sterile pustules, continued to appear. Histopathologic analysis of a skin biopsy specimen confirmed the diagnosis of eosinophilic pustular folliculitis. Direct immunofluorescence tests was negative; the eosinophil count in a chamber was 44/mm3 of blood. The eruption persisted despite the administration of dapson (100 mg/d). dexamethason (3 mg/d) and diklofenak-sodium (100 mg/d). Indometacin (75 mg/d) led to complete remission within 5 weeks but failed to control periodic recurrences during the following year, as did diverse topical and oral medications. Systemic PUVA therapy (IO J/cm?) led to partial clearance of the skin lesions and pruritus in 3 weeks. Our patient is particularly interesting due to the fact that she is a Caucasian female with Ofuji’s folliculitis localized to the scalp and resistant to various treatment modalities. I P290
The factors that promote ruber planus in Estonia
developing
H. Silm, S. Kaur, M. Karelson, K. Kingo. I P288
folliculitis
Dematology
Tartu
University,
Department
lichen of
Estonia
Lichen ruber planus (LP) accounts for about 0.7-0.8 per cent of dermatological outpatients in Britain and Nortb America. The same could be said about the situation in Estonia. During big changes in our economic, social and political life after 1991 the incidence of LP increased (2-38). There is considerable evidence that underlying processes involved in the pathogenesis of LP are immunologicaJly mediated. The aim of this paper is to investigate the factors promoting the development of LP in Estonia. We analysed 108 cases of LP treated at the Clinic of Dermatology of Tartu University in 1993-1997. On the basis of our investigation we can draw the conclusion that (a) stress may be considered the most important factor promoting the development of LP (b) LP was contracted more Frequently by patients who were suffering from diabetes mellitus. (c) All our patients with LP had had different tumors in their family histories. (d) The results of our research should be considered in carrying out adequate treatment according to promoting factors.