Lipoid proteinosis of the larynx: a cause of voice change in the infant and young child

33

~ep4rtment

of Otolarynsoogy

Key words: Li

~roteimosis;Larynx; Wrbach-

+ Presented at the American bciety of 1987. Correspondence:

fomia and Child

ay 3,

seen in 1971 when she present a weak cry from birth.

material was no

absent lateral incisors ation included skull

f normal cognitive abilities. with a complaint of deterioration of

vibratory movements of the vocal

35

Fig. 1.

antles ofhyalin around blood vesselsperiodicacid-Sc

tives

with Oil red 0 in&a’* lipids.( X200.)

the presenceof neutral

38

patient who had livedI a full and normal life without medical ~te~en~~~~. ~tho~~ death from respiratory obstruction has been reported in the earlier literature, this QIII be avoided presentiy by recognition of the disease and rn~t~~~e of the airway. As derno~~at~ in the case presented herein, laser ~~ol~~o~opy may be utilized to preserve and improve the voice and obviate the need for tracheostomy insomethat this r~rt w3l serve to aphasic lipoid ~~te~osis as a cause of in the infant and young child. The voice changes result from multi-level ary to the disease including involvement of the larynx as a sound as 8 I e curd p&ate 8s ~~~~~tors

1 Aa& MT,, Nandour, MA., k?l=Oh

2 3 4 5 6

‘, I.F., B&4, A,=BA. and Tallant, A.M., Urbach-Wicthe

de la peau et das ~uq~~~~: uqueuse, lpressei&L, 70 (1%2) 973-975. Ckplaa, RM., Visceralinvolvementin lipoid protainosis,Awh. Detmatol., 95 (1967) 149-155. C&en, S.R, Thcmpson, J.W., oeller, R.A. and Bir, J ~ff~d~ diagmais, Ann. Otol. Rhino). Laryngoll.,92 (1 Dickey, RF. and Davis, S., Lipoid pmteinosis (Wrbach (1964) 287-296. Flwjet, R, TimpI, R. and Orwes, P., Hyalinosis cutis et muwsaf. A basal Iamina disease, and Standbouders,A.M., and Moffat, B.A., Qlo~h~g~

alinosis cutis et

an

llipoid proteinosis: hyalinosis cutis et osis cutis et mucosae, Arch. Dermatol,, 75 and reviewof literature,

goscope, 58 (1948)

H. aad Hams, FZ., Xanthomatosis:Iv. Lipoid proteimsis (phosphatide lipoidosis), darSchleimhautbei aUgmminerhyperkeratosedtx Ham, Arch. of lipoidosiscutes et mucosal~so-called“lipoid proteinosis”,Urbach-Wiethe, E. and Wiethc, C., Lipoidosis cutis et mucosae. Viiows 16 Wialhe, C., Uber lokale ~y~rnab~a~ 237-240.

in den

Arch. Pathoi. Anat., 273 (1929)

n Luftwe8en.Acta. Otolaryn~ol.,10 (1926)