- Email: [email protected]
Liquid chromatography in clinical analysis
Journal of Biochemicaland BiophysicalMethods, 5 ( 1981) 187 © Elsevier/North-HollandBiomedicalPress
187
Book review Liquid Chromatography in Clinical Analysis Kabra, P.M. and Marton, L.J. (eds.) Humana Press, Clifton, N.J. (1981)
This book on the use of high-pressure liquid chromatography in clinical analysis is intended to serve as a reference for scientists involved in patient care monitoring. The book consists of 19 chapters and is divided into three parts. Part 1: Introduction to Liquid Chromatography. A brief chapter on liquid chromatography theory is followed by chapters on instrumentation for high-pressure liquid chromatography and column technology. The chapter on instrumentation should be particularly useful for those people considering the purchase of highpressure liquid chromatography equipment. A description of the different components which integrate our liquid chromatography system should allow the reader to define his or her needs and hence equipment selection will be more cost effective. Part 2: Therapeutic Drug Monitoring and Toxicology. These eight chapters provide information on applications of high-pressure liquid chromatography to the monitoring of anticonvulsants, theophylline, antibiotics, tricyclic antidepressants, antineoplastic drugs, hypnotics and sedatives. Of particular interest are the use of high pH buffer eluents (Chapter 8, tricyclic antidepressants) and rapid UV scanning techniques for the determination of barbiturates in serum samples (Chapter 11, toxicology screening). Part 3: Clinical Analysis of Endogenous Constituents. These eight chapters contain applications of high-pressure liquid chromatography to the analysis of catecholamines, steroids, proteins, bilirubin and its conjugates, porphyrins, organic acids, nucleosides and polyamines. In this part, as in the previous one, the subject coverage is excellent with some surprisingly detailed experimental procedures. This book is essentially a collection of individual accounts in specific areas of clinical analysis. Each chapter is self-contained and as such a certain lack of continuity is present. The specific coverage provided on the subjects compensates for this minor point. Both newcomers to the field and experienced workers should find this book useful. D. Hernandez NIEHS, NIH, Research Triangle Park, N. C
187
Book review Liquid Chromatography in Clinical Analysis Kabra, P.M. and Marton, L.J. (eds.) Humana Press, Clifton, N.J. (1981)
This book on the use of high-pressure liquid chromatography in clinical analysis is intended to serve as a reference for scientists involved in patient care monitoring. The book consists of 19 chapters and is divided into three parts. Part 1: Introduction to Liquid Chromatography. A brief chapter on liquid chromatography theory is followed by chapters on instrumentation for high-pressure liquid chromatography and column technology. The chapter on instrumentation should be particularly useful for those people considering the purchase of highpressure liquid chromatography equipment. A description of the different components which integrate our liquid chromatography system should allow the reader to define his or her needs and hence equipment selection will be more cost effective. Part 2: Therapeutic Drug Monitoring and Toxicology. These eight chapters provide information on applications of high-pressure liquid chromatography to the monitoring of anticonvulsants, theophylline, antibiotics, tricyclic antidepressants, antineoplastic drugs, hypnotics and sedatives. Of particular interest are the use of high pH buffer eluents (Chapter 8, tricyclic antidepressants) and rapid UV scanning techniques for the determination of barbiturates in serum samples (Chapter 11, toxicology screening). Part 3: Clinical Analysis of Endogenous Constituents. These eight chapters contain applications of high-pressure liquid chromatography to the analysis of catecholamines, steroids, proteins, bilirubin and its conjugates, porphyrins, organic acids, nucleosides and polyamines. In this part, as in the previous one, the subject coverage is excellent with some surprisingly detailed experimental procedures. This book is essentially a collection of individual accounts in specific areas of clinical analysis. Each chapter is self-contained and as such a certain lack of continuity is present. The specific coverage provided on the subjects compensates for this minor point. Both newcomers to the field and experienced workers should find this book useful. D. Hernandez NIEHS, NIH, Research Triangle Park, N. C