List of Abbreviations Used in This Book

XI

LIST OF ABBREVIATIONS USED IN THIS BOOK

a-

x

atto- ( 1 0 - l ~ )

Ab

antibody

angstrom

ACTH

adrenocorticotropin hormone

Ag

antigen

Ag* amino acids

radioactive antigen ( A = ala; C = cys; D = asp; E = glu;

F = phe; G = gly; H = his; I = ile;

K = lys; L = leu; M = met; N = asn; P = pro; Q = gln; R = arg; S = ser; T = t h r ; V = Val; W = t r p ; Y = t y r ) a.m.u.

atomic mass units

API

atmospheric pressure ionization

AUFS

absorbance units full scale

B

magnetic field

Bmax BA

bioassay

maximum binding

BIE

ratio of magnetic-to-electric fields

BIF

ratio of bound-to-free

‘18 CAD

octadecyl collision activated dissociation, collisionally activated dissociation. Also, collision (ally) induced dissociations.

Also, instead of

dissociations, decompositions may be used

CCK

c holecystokinin

CI

chemical ionization

CLIP

corticotropin-like intermediate peptide

CNS

central nervous sytem

CRF

corticotropin releasing factor

CSF

cerebrospinal fluid

DAD1

direct analysis of daughter ions

XI1 DAP

dipep tidy laminopep tidase

DCI

direct chemical ionization

DFI

direct fluid injection

DLI

direct liquid injection

E

electric field

EI

electron ionization

f-

femto- ( 1 0 - l ~ )

FAB

fast atom bombardment

FD

field desorption

FFR

f ield-free region

fmol

femtomole

fsec

femtosecond

GABA

gamma aminobutyric acid

GC

gas chromatography

GC-MS

gas chromatography-mass spectrometry gigahertz (109H z )

GHz GI

gastrointestinal

HAc

acetic acid

HETP

height equivalent to theoretical plate

HPLC

high performance liquid chromatography

IKE(S)

ion kinetic energy (spectroscopy)

ir

immunoreactive

Ka KeV

binding constant kilo-electron volts

LC

liquid chromatography

LC-MS

liquid chromatography-mass spectrometry

LC-MS-MS

liquid chromatography-mass spectrometrymass spectrometry

LE

leucine enkephalin (YGGFL)

LPH

beta lipotropic hormone

M+'

molecular ion-radical

(M+H)+

protonated molecula'r ion

MeV

million electron volts

ME

methionine enkephalin (YGGFM)

MIKE ( s )

mass-analyzed ion kinetic energy (spectroscopy)

msec

millisecond

M SH

alpha melanocyte stimulating hormone

XI11

MSIMS

mass spectrornetrylmass spectrometry

MW

molecular weight

also, tandem mass spectrometry

N-

amino end of a peptide

nl

nanoliter

nm

nanometer

NMR

nuclear magnetic resonance

l80

180xygen

ODS

octadecylsilyl

PPCA

pyrrolidone carboxylic acid

pico- (

PD

plasma desorption

PGE2

prostaglandin E

pmol

picomole

POMC

pro-opiomelanocortin

2

Q

quadrupole

QET RF

quasi-equilibrium theory radio frequency

RIA

radioimmunoassay

RP

reversed phase

RRA

radioreceptor assay

SFC

supercritical fluid chromatography

SIM

selected ion monitoring

SIM S

secondary ion mass spectrometry

TAME

para-toluenesulfonylarginine methyl ester

TEAF

triethylamine: formate

TEAP

t rie t hylamine :phosphate

TPCK

tosylamide-2-phenylethyl chloromethyl ketone

TR F

thyrotropin releasing factor

Tris

2-amino-Z-hydroxmethyl-l , 3-propanediol

TSH

thyroid stimulating hormone

TSQ

triple stage quadrupole

uv

ultraviolet

V

ion accelerating voltage

VIP

vasoactive intestinal peptide