- Email: [email protected]
Low-temperature plasma in biology and medicine
Accepted Manuscript Editorial: Low-temperature plasma in biology and medicine Masaru Hori, Eun Ha Choi, Shinya Toyokuni PII:
S0003-9861(16)30200-4
DOI:
10.1016/j.abb.2016.06.014
Reference:
YABBI 7310
To appear in:
Archives of Biochemistry and Biophysics
Please cite this article as: M. Hori, E.H. Choi, S. Toyokuni, Editorial: Low-temperature plasma in biology and medicine, Archives of Biochemistry and Biophysics (2016), doi: 10.1016/j.abb.2016.06.014. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Editorial: Low-temperature plasma in biology and medicine
AC C
EP
TE D
M AN U
SC
RI PT
During the last decade, a passionate scientific movement has emerged, which seeks to use plasma in medical instruments and therapeutics [1-3]. Plasma is defined here as the 4th type of physical state, in addition to the well-known solid, liquid, and gas states. It is a mixture of such components as gas, radicals, electrons, cations, anions, and UV. Plasma is associated with the origin of the universe because space is full of plasma, as represented in the case of the sun [4]. Lightning [5] and aurora [6] are examples of plasma on Earth, and we believe that plasma also acted on other organic and inorganic molecules on Earth to spawn primitive life forms. High-temperature (thermal) plasma (> several thousand K) has been used worldwide since the 1960s for industrial purposes, such as manufacturing semiconductors and circuit boards (i.e., plasma engineering) [7]. From the 1990s, it became possible to generate low-temperature (non-thermal) plasma, which is close to the temperature of the human body. Since the 2000s, low-temperature plasma has spurred a novel area of biochemistry and biophysics, thus inaugurating a new era of biology and medicine. Recently, through the direct exposure of low-temperature plasma, many chemical species have been identified in plasma, including hydroxyl radicals, hydrogen peroxide, superoxide and nitric oxide [8, 9]. Plasma-activated medium (liquid) offers another modality for exploring the biological applications of plasma [10]. During the last decade, the number of publications on low-temperature plasma exponentially increased, and many new journals on this subject were launched. This timely special issue of Archives of Biochemistry and Biophysics was planned at the 10th Asian-European International Conference on Plasma Surface Engineering, which convened in Jeju, Korea, on September 20-24, 2015. This special issue contains 16 original or review articles. All of them are cuttingedge articles that discuss low-temperature plasma from diverse aspects, namely, the apparatus [11, 12]; the chemical species involved [13-15]; manufacturing medical materials [16, 17]; transfection [18]; disinfection [19, 20]; wound healing [21, 22]; cancer therapeutics [23, 24]; and plant biology [25, 26]. For the first time, we have flexible and versatile strategies to load near-natural oxidative stress to any location. Biology and medicine have thus become candidates for the use of low-temperature plasma, including in regenerative medicine. We sincerely hope this special issue will help promote this novel research area.
Masaru Hori* Nagoya University Graduate School of Engineering, Nagoya, Japan [email protected]
ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
Eun Ha Choi* Kwangwoon University, Seoul, Korea [email protected] Shinya Toyokuni* Nagoya University Graduate School of Medicine, Nagoya, Japan [email protected] *Corresponding authors
S0003-9861(16)30200-4
DOI:
10.1016/j.abb.2016.06.014
Reference:
YABBI 7310
To appear in:
Archives of Biochemistry and Biophysics
Please cite this article as: M. Hori, E.H. Choi, S. Toyokuni, Editorial: Low-temperature plasma in biology and medicine, Archives of Biochemistry and Biophysics (2016), doi: 10.1016/j.abb.2016.06.014. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Editorial: Low-temperature plasma in biology and medicine
AC C
EP
TE D
M AN U
SC
RI PT
During the last decade, a passionate scientific movement has emerged, which seeks to use plasma in medical instruments and therapeutics [1-3]. Plasma is defined here as the 4th type of physical state, in addition to the well-known solid, liquid, and gas states. It is a mixture of such components as gas, radicals, electrons, cations, anions, and UV. Plasma is associated with the origin of the universe because space is full of plasma, as represented in the case of the sun [4]. Lightning [5] and aurora [6] are examples of plasma on Earth, and we believe that plasma also acted on other organic and inorganic molecules on Earth to spawn primitive life forms. High-temperature (thermal) plasma (> several thousand K) has been used worldwide since the 1960s for industrial purposes, such as manufacturing semiconductors and circuit boards (i.e., plasma engineering) [7]. From the 1990s, it became possible to generate low-temperature (non-thermal) plasma, which is close to the temperature of the human body. Since the 2000s, low-temperature plasma has spurred a novel area of biochemistry and biophysics, thus inaugurating a new era of biology and medicine. Recently, through the direct exposure of low-temperature plasma, many chemical species have been identified in plasma, including hydroxyl radicals, hydrogen peroxide, superoxide and nitric oxide [8, 9]. Plasma-activated medium (liquid) offers another modality for exploring the biological applications of plasma [10]. During the last decade, the number of publications on low-temperature plasma exponentially increased, and many new journals on this subject were launched. This timely special issue of Archives of Biochemistry and Biophysics was planned at the 10th Asian-European International Conference on Plasma Surface Engineering, which convened in Jeju, Korea, on September 20-24, 2015. This special issue contains 16 original or review articles. All of them are cuttingedge articles that discuss low-temperature plasma from diverse aspects, namely, the apparatus [11, 12]; the chemical species involved [13-15]; manufacturing medical materials [16, 17]; transfection [18]; disinfection [19, 20]; wound healing [21, 22]; cancer therapeutics [23, 24]; and plant biology [25, 26]. For the first time, we have flexible and versatile strategies to load near-natural oxidative stress to any location. Biology and medicine have thus become candidates for the use of low-temperature plasma, including in regenerative medicine. We sincerely hope this special issue will help promote this novel research area.
Masaru Hori* Nagoya University Graduate School of Engineering, Nagoya, Japan [email protected]
ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
Eun Ha Choi* Kwangwoon University, Seoul, Korea [email protected] Shinya Toyokuni* Nagoya University Graduate School of Medicine, Nagoya, Japan [email protected] *Corresponding authors