Journal Pre-proof Making the economic value proposition for pharmacist comprehensive medication management (CMM) in primary care: A conceptual framework Kristen Tripicchio, Benjamin Urick, Jon Easter, Sachiko Ozawa PII:
S1551-7411(19)30561-3
DOI:
https://doi.org/10.1016/j.sapharm.2020.01.001
Reference:
RSAP 1426
To appear in:
Research in Social & Administrative Pharmacy
Received Date: 19 August 2019 Revised Date:
15 December 2019
Accepted Date: 1 January 2020
Please cite this article as: Tripicchio K, Urick B, Easter J, Ozawa S, Making the economic value proposition for pharmacist comprehensive medication management (CMM) in primary care: A conceptual framework, Research in Social & Administrative Pharmacy (2020), doi: https:// doi.org/10.1016/j.sapharm.2020.01.001. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier Inc.
Kristen Tripicchio: Conceptualization, Methodology, Writing – Original Draft, Visualization Sachiko Ozawa: Methodology, Writing – Review & Editing, Supervision, Validation Jon Easter: Conceptualization, Writing – Review & Editing Benjamin Urick: Validation, Writing – Review & Editing
Making the Economic Value Proposition for Pharmacist Comprehensive Medication Management (CMM) in Primary Care: A Conceptual Framework Kristen Tripicchio, PharmD,a Benjamin Urick, PharmD, PhD,a Jon Easter, RPh,a and Sachiko Ozawa, PhDa,b a
Division of Practice Advancement and Clinical Education, University of North Carolina Eshelman School of Pharmacy, 301 Pharmacy Lane, Chapel Hill, NC, 27599, USA. b Department of Maternal and Child Health, University of North Carolina Gillings School of Global Public Health, 135 Dauer Drive, Chapel Hill, NC, 27599, USA. Corresponding Author: Kristen Tripicchio,
[email protected]
1
ABSTRACT
2
Introduction
3
Comprehensive medication management (CMM) is a patient care process provided by clinical
4
pharmacists in primary care settings that ensures optimal use of medications with timely follow-up.
5
Despite widespread evidence that shows CMM improves clinical and medication-related outcomes,
6
pharmacist-delivered CMM services often fail to be adopted into U.S. primary care settings.
7 8
Objective
9
This study presents a conceptual framework linking outcomes of pharmacist-delivered CMM services in
10
primary care settings to financial benefits for health plans providing coverage of CMM services and
11
primary care practices investing and implementing CMM.
12 13
Methods
14
A critical review of the literature was performed in PubMed and the gray literature to identify financing
15
opportunities that justify the coverage of CMM by third-party health plan administrators or the
16
implementation of CMM by primary care practices. Financing elements that could be impacted by
17
pharmacist-led CMM outcomes, namely higher achievement of medication-related quality measures and
18
reduction of total costs of care, were recorded and utilized to develop the conceptual framework.
19 20
Results
21
The framework suggests that CMM provides economic benefits to both health plans and primary care
22
practices by increasing market competitiveness, direct revenue, and quality bonuses. Health plans may
23
benefit from higher plan quality ratings, lower premiums and plan bids, increased shared savings, and
24
quality bonus payments. Primary care practices may achieve increased negotiating power through
25
accreditation recognition and patient satisfaction, increased revenue through shared savings and fee-for-
26
service reimbursement, and achievement of quality bonus payments.
27 28
Conclusions
29
The alignment of economic benefits from CMM advances a strong value proposition for greater adoption
30
of CMM coverage by health plans and implementation in the U.S. primary care system. Through broader
31
CMM implementation, pharmacists can work alongside physicians in advanced care models and play a
32
vital role in shaping the primary care practice transition to value-based care.
33
34
Keywords: Comprehensive Medication Management (CMM); clinical pharmacy; medication
35
optimization; pharmacist reimbursement; economic framework; business plan; quality of care
36
INTRODUCTION
37
The misuse, underuse, and overuse of medications is one of the largest preventable factors contributing to
38
lower health care quality in the United States. While retail prescription drug spending in the U.S. is
39
estimated to be $330 billion of the $3.3 trillion in total health expenditures, costs resulting from non-
40
optimized medication therapy have been estimated to exceed $500 billion.1,2 This implies that for every
41
dollar spent on medications in the United States, an additional dollar is needed to address inappropriate
42
medication use. One solution for reducing unnecessary medication-related spending is comprehensive
43
medication management (CMM), a clinical service delivered by pharmacists using an integrated care
44
team approach. The CMM patient care process ensures that each patient’s medications are evaluated to
45
determine appropriateness, effectiveness, safety, adherence, and accessibility.3 Clinical pharmacists
46
performing CMM services develop and implement an individualized medication therapy care plan in
47
collaboration with the patient and care team. Regular follow up and monitoring are essential to the CMM
48
process in order to ensure optimal medication use, achieve patient-specific goals of therapy, and deliver
49
quality outcomes.3
50 51
Pharmacist-led CMM has consistently demonstrated positive clinical outcomes, which are most often
52
achieved through identification and resolution of medication therapy problems (MTPs). Examples of
53
relevant CMM interventions include addition of an indicated medication such as a statin or asthma inhaler
54
therapy, dose optimization of anti-diabetic agents, or discontinuing an unsafe or unnecessary medication
55
such as agents that cause confusion in elderly patients.4 On average, studies of CMM services have
56
identified and resolved 4.5 MTPs per patient, with the most frequent types of MTPs identified as
57
requiring additional medication therapy or suboptimal dosing of an existing therapy.5–14 In terms of
58
diabetes management, studies have shown that CMM leads to significant reductions in hemoglobin A1c
59
compared to control arms with estimated treatment differences ranging from -0.4% to -1.7%.15–19
60
Moreover, several studies have demonstrated CMM’s positive impact on all-or-none diabetes composite
61
scores that involve achievement of several important treatment goals including smoking cessation, daily
62
aspirin use, and meeting targets for A1c, low density lipoprotein (LDL), and blood pressure goals.6–8,16
63 64
These clinical benefits have also resulted in cost savings. Some studies of well-adopted CMM services
65
have demonstrated a positive impact on lowering patient total cost of care by decreasing hospitalizations
66
and other acute care utilization.9,14 Studies reporting the impact of CMM on total patient cost of care
67
report total annual savings ranging from $452 to $3678 per patient.8,9,13,14,17 When implemented
68
consistently and appropriately, CMM has demonstrated a positive return on investment as high as $12 for
69
every $1 invested in primary care practice settings.14
70
Despite widespread evidence that shows CMM improves clinical and medication-related outcomes,
71
pharmacist CMM services fail to be widely adopted into U.S. primary care settings.20–23 CMM services
72
are often funded through unsustainable means such as temporary grants,12,13,17,24 pilot programs,9 or
73
limited fee-for-service billing reimbursements.6,7,10,11 Fortunately, the current healthcare policy landscape
74
and value-based directive in the U.S. presents a favorable environment for the economic justification of
75
pharmacist CMM services. In the new age of emphasis on value and the partial transfer of risk from
76
payers to delivery systems, CMM has the potential to be financially viable.25,26 This study presents a
77
theoretical framework to conceptualize how CMM-driven outcomes can financially benefit third-party
78
health plans and primary care delivery systems deliberating about whether to reimburse for or implement
79
pharmacist CMM services.
80 81
METHODS
82
A critical review of the literature was performed to discern financing opportunities that justify the
83
coverage of CMM by third-party health plan administrators or the implementation of CMM by U.S.
84
primary care practices. The literature review focused on financing elements between U.S. healthcare
85
financers (individuals, employers, and government), third-party health plan administrators, and primary
86
care delivery systems. Specifically, the scope of the framework was limited to health insurance through
87
Medicare, Medicaid, fully or self-insured employers, and state or federally run health insurance
88
exchanges as these make up the bulk of health financing in the United States.27–29 Financing of primary
89
care practices - including physicians organized into accountable care organizations (ACOs) or patient-
90
centered medical homes (PCMHs) - was also evaluated.
91 92
Literature searches were conducted in PubMed and the gray literature through use of key terms and
93
synonyms that reflected financing models between each of the chosen stakeholders. Terms used to
94
identify financing models included: reimbursement, payment, financing, contract, revenue, business
95
model, and remuneration. These financing search terms were combined to discern revenue streams from
96
the selected lines of business for health plans (i.e. Medicare Advantage plans, Medicare Part D plans,
97
commercial plans, Medicaid managed care, fully-funded insurers) and for primary care practices (i.e. self-
98
insured employers, commercial health plan contracts, traditional Medicare, Medicare Advantage, and
99
Medicaid). Titles and/or abstracts were scanned to identify articles that discussed relevant revenue
100
models. For financing elements where more detailed information was available (e.g. Medicare Advantage
101
Stars quality bonus payments), secondary searches were performed in the gray literature (i.e. Centers for
102
Medicare and Medicaid Services (CMS), Healthcare Effectiveness Data and Information Set (HEDIS),
103
PCMH accreditation, and ACO accreditation websites) to understand contract specifics such as relevant
104
quality metrics or risk-adjustment factors. Financing elements that could be impacted by the stated
105
paradigm were recorded and utilized to develop a conceptual framework.
106 107
In order to develop the narrative framework, a paradigm was applied that presumes pharmacist CMM
108
services result in lower total costs of care through decreased acute care utilization and higher achievement
109
of medication-related quality measures. Thus, financing elements that could be positively impacted by
110
either lower total costs of care or higher achievement of quality measures were assumed to contribute to
111
the economic justification for CMM. This paradigm is supported by the literature and continues to be
112
evaluated as the value of clinical pharmacy services gains national attention.30,31 We present the
113
framework through two perspectives – from the standpoint of third-party health plans and primary care
114
practices.
115 116
RESULTS
117 118
CMM Value Proposition within the U.S. Healthcare System: A Conceptual Framework
119
This framework presents the economic value proposition for CMM in primary care settings (Figure 1).
120
Within the framework are three key categories of stakeholders: 1) healthcare financers (i.e. employers,
121
individuals, and government programs for Medicare and Medicaid), 2) third-party health plan
122
administrators (TPAs) that facilitate contracts and health benefits on behalf of financers, and 3) primary
123
care practices where CMM services may be delivered. In general, payers receive financing from
124
healthcare financers (yellow dotted and blue arrows in Figure 1), and then go on to pay primary care
125
practices for rendered services (green dashed arrows in Figure 1). Primary care practices may also receive
126
reimbursement directly from certain healthcare financers, including traditional Medicare, non-managed
127
Medicaid, and self-insured employers (green dashed arrows in Figure 1). The following sections will
128
narrate how clinical and economic outcomes from CMM services can benefit both third-party health plans
129
and primary care delivery systems through various mechanisms elucidated from the literature review.
130 131
CMM From a Third-Party Health Plan Perspective
132 133
The primary lines of business for third-party health plans include commercial plan contracts purchased by
134
fully-insured employers or individuals, Medicare Advantage (MA) plans, and state Medicaid managed
135
care plans. CMM has the opportunity to benefit all lines of business through the following financing
136
elements: (1) increase market competitiveness, (2) increase direct revenue from capitated shared savings
137
contracts, and (3) achieve quality-related bonus payments.
138 139
Coverage of CMM services may increase health plan market competitiveness by lowering total medical
140
costs, thus allowing plans to offer lower premiums within the commercial market or lower their bids
141
within request for proposals (RFPs) to Medicare and Medicaid.32 In addition, CMM has the potential to
142
increase market competitiveness by improving plan ratings. In the commercial market, the National
143
Committee for Quality Assurance (NCQA) accredits health plans and assigns plan quality ratings, both of
144
which are essential for winning contracts from large employers looking to provide a high-quality benefit
145
package to their employees.33,34 NCQA ratings and accreditation are based on achievement of HEDIS
146
quality measures including processes (e.g. statin therapy in cardiovascular disease), outcomes (e.g.
147
controlled A1c, reduction in hospitalizations), and patient experience measures.34,35 Over 30% of HEDIS
148
quality measures are related to medications or medication-related treatment outcomes that are either a
149
result of CMM MTP resolution (e.g. addition of an indicated statin) or that serve as a goal of CMM care
150
(e.g. controlled blood pressure).35 Similarly, in the Medicare market, Star Ratings serve as a way to rank a
151
high-quality plan. Of the 48 Stars Measures for 2018, 15 (31%) are either related to medication
152
management (e.g. diabetes medication adherence, achievement of blood pressure control) or outcomes
153
positively influenced by CMM such as hospital readmissions (see Table 1).36 In addition, these measures
154
are more heavily weighted and end up contributing to greater than 31% of the calculated plan score. Of
155
note, 66% of Medicare Advantage enrollees in 2017 were enrolled in a plan with a Star Rating of 4 or
156
more Stars on the 5-Star scale, indicating the impact of high-quality ranking on member enrollment, and
157
thus plan competitiveness.29
158 159
Through lowering the cost of care and higher achievement of quality measures, CMM can benefit plans’
160
direct revenue for those engaged in capitated shared savings contracts such as the Medicare Advantage
161
payment system. In the MA market, plans submit bids to CMS that estimate the cost to cover an average
162
beneficiary. Plans who submit bids lower than the CMS calculated benchmark rate have the opportunity
163
to gain a portion of the “savings” (difference between the benchmark and plan bid).32 Lowering the total
164
cost of care of a plan population through appropriate medication management can help plans achieve
165
lower bids and recoup a larger magnitude of savings.
166 167
Lastly, by improving HEDIS or Star quality measures, CMM has the potential to offer quality bonuses to
168
plans. In the Medicare Advantage market, the proportion of savings that is repaid to Medicare Advantage
169
plans, also known as the MA rebate, is entirely dictated by a plan’s Star Ratings. Known as a Quality
170
Bonus Payment, the CMS calculated benchmark is increased by 5% for plans who achieve a Star rating of
171
4 or higher, allowing these plans to have a wider spread between their quality-adjusted benchmark and
172
original plan bid. The shared savings’ rebate percentage that a plan recoups is also influenced by Star
173
ratings. Plans with 4.5 stars or higher receive a 70% rebate, whereas plans with 3 stars or lower only
174
receive a 50% rebate.37 Notably, quality bonus payments are also becomingly increasing more common in
175
some state Medicaid programs such as New York, where plans may receive bonuses upon high quality
176
measure performance.38
177 178
CMM From a Primary Care Practice Perspective
179 180
Primary care practices may be primarily funded through traditional fee-for-service (FFS) reimbursement
181
or organized into models where care coordination, quality, and cost-effectiveness are emphasized such as
182
PCMHs or ACOs. Depending on the practice structure, CMM has the opportunity to benefit primary care
183
practices through three financing elements: (1) increased market competitiveness, (2) increased direct
184
revenue from traditional FFS payments or shared savings, and (3) quality bonus payments.
185 186
Integrating CMM into primary care practices can increase market competitiveness with consumers and
187
health plans. Consumers have demonstrated high patient satisfaction with CMM services and increased
188
confidence in managing their diseases.5,6,11,15 Practices may use patient anecdotes as a marketing tactic to
189
increase patient volume. In addition, CMM can increase practices’ contract negotiating power with health
190
plans. First, CMM can help improve quality metrics, patient satisfaction, and acute care utilization, which
191
provide important data that can be leveraged in insurer negotiations.6,9,18 Second, CMM implementation
192
can help with requirements for ACO or medical home accreditations, which are often required for
193
inclusion in payer networks. For example, NCQA’s PCMH recognition process requires team-based care,
194
delivery of guideline-directed care, medication education and counseling, establishment of person-
195
centered care plans for high risk patients, and other requirements that are essential components of the
196
CMM care process that may otherwise not be formally integrated into the primary care practice.39
197 198
Pharmacist-delivered CMM services can also generate direct revenue from traditional FFS billing, PCMH
199
and ACO payments, and capitated shared savings. Although FFS reimbursement is often insufficient to
200
cover all costs associated with CMM, it can provide consistent supplemental revenue in addition to the
201
other economic benefits discussed in this framework. Certain states such as Minnesota have recognized
202
the value of pharmacist CMM services and have created a FFS reimbursement structure to recognize
203
CMM care delivery.7 In other states, FFS billing for CMM can either be achieved directly though current
204
procedural terminology (CPT) code 99211 ($20-$30) or through physician “incident-to” billing for a
205
variety of scenarios where reimbursement may range from $40 to $226 (see Table 2).40 These may
206
include transitional care management (CPT 99495, 99496), annual wellness visits (G0438, G0439), or
207
newer chronic care management codes (CPT 99490).41 Practices have the opportunity to be innovative
208
with the CMM care process in order to receive maximal reimbursement. Two real-world examples of this
209
include incorporating Annual Wellness Visits into the CMM process29 and physician-pharmacist co-visit
210
models that allow for physicians to see more patients daily and bill at a higher complexity.42 In addition,
211
PCMH and ACO accredited practices can receive direct increases in their contract revenue in the form of
212
additional care management fees or shared savings that are weighted based on quality.43,44 Lastly, by
213
lowering acute care utilization, CMM has the potential to increase shared savings for primary care
214
practices where capitation is the primary reimbursement model such as in ACOs. As health systems take
215
on more risk for attributed patient panels, investment in services that aim to manage chronic disease and
216
prevent avoidable complications will be integral for driving revenue.45
217 218
Practices can also obtain quality bonus incentive payments with commercial and government payers
219
through the Merit-based Incentive Payment System (MIPS) and pay-for-performance (P4P) models.46,47
220
Due to the recent Medicare physician reimbursement overhaul known as the Medicare Access and CHIP
221
Reauthorization Act (MACRA) of 2015, primary care physicians will be engaged in upside-downside risk
222
adjustments that can affect up to 9% of their Medicare reimbursements.47 These adjustments will be based
223
on MIPS composite scores that incentivize quality, efficient resource utilization, practice quality
224
improvement activities, and advancement of health information technology. As of 2019, 60% of the MIPS
225
score is made up of achievement of quality measures and resource utilization (i.e. cost of medical claims),
226
which may be positively influenced by CMM interventions.47 Several MIPS quality measures are related
227
to chronic medication management such as evidence-based therapy for heart failure, improvement in
228
blood pressure, and optimal asthma control.48 In addition to Medicare’s MIPS program, pay-for-
229
performance models are another form of quality bonus payments. P4P arrangements vary widely and are
230
ubiquitous across Medicare, Medicaid, and commercial contracts.46 P4P may be based on achievement of
231
quality measures such as following guideline-based therapy or lowering acute care utilization, both of
232
which are supported by the CMM care model.
233 234 235
DISCUSSION
236
This study presents a novel conceptual framework describing the economic value proposition for CMM in
237
the U.S. healthcare system. The framework demonstrates aligned economic justification for CMM by
238
both primary care practices investing and implementing CMM and health plans providing coverage and
239
reimbursement of CMM services. Namely, health plans and primary care practices alike may improve
240
market competitiveness, increase direct revenue, and achieve quality bonuses by adopting and paying for
241
CMM. These financial opportunities posit a value proposition for CMM services in U.S. primary care
242
settings, which can aid greater numbers of practices to adopt CMM services. This work can serve as a
243
launching point for negotiations or business plan development for primary care practices looking to
244
convince health plans to reimburse for CMM within their contracts, or for pharmacists looking to
245
convince health system administrators to implement CMM services at their institutions.
246 247
In order to help promote effective expansion of CMM, stakeholders will have to be committed to
248
documentation and tracking of outcomes, partnering in quality-based analytics, and considering physician
249
buy-in. To promote CMM as a sustainable and integrated service within health system budgets, care
250
practices must be committed to tracking CMM interventions and outcomes. By continuously generating
251
evidence for CMM services, care practices will be able to leverage these outcomes in payer negotiations
252
and with health system leadership. These efforts can help move CMM funding from short-term and
253
limited sources to fully integrated into health system budgets. One potential innovation that may help
254
with tracking outcomes is the introduction of Systematized Nomenclature of Medicine - Clinical Terms
255
(SNOMED CT) codes, a new coding system to record care interventions in electronic health record
256
(EHR) systems. Adoption and consistent use of SNOMED CT codes as a way to track and monitor
257
interventions made by pharmacists can present an opportunity to make a more convincing value argument
258
for CMM.49 In addition, health plans willing to recognize CMM in contract negotiations can also partner
259
with care practices to share and generate evidence for CMM patients utilizing claims-level data. This may
260
help further demonstrate the value of CMM services on a macro level.
261 262
The focal point of CMM revenue opportunities for health plans and primary care practices is centered
263
around the achievement of value-based quality measures as well as lowering total medical costs. As the
264
sustainability of CMM implementation is based on these quality outcomes, practices and health plans
265
should carefully consider quality measures they are held accountable for and create infrastructure to help
266
improve those outcomes. Health plans should focus on using analytics to identify quality measure
267
opportunities, enhance communication and data-sharing with providers and primary care practices to
268
address those gaps, and support practice-level incentives for quality measures that can help fund and
269
sustain CMM services. Similarly, primary care practices should partner with health plans to leverage their
270
data capabilities to identify and improve quality measure opportunities. Primary care practices should also
271
ensure to educate providers and primary care team members about the importance of quality-based
272
initiatives and to develop agility in their care models in order to continuously address population-level
273
gaps in care.
274 275
While our conceptual framework focuses on a financial justification for CMM services, widespread
276
adoption of this care model also requires buy-in from providers. Fortunately, physicians in primary care
277
practices that have fully adopted CMM have reported high satisfaction with CMM and improvement in
278
their work-life as a result of having pharmacist partners in their practices. Specifically, physicians have
279
reported decreased workload, satisfaction that patients are receiving better care, reassurance, decreased
280
mental exhaustion, enhanced professional learning, increased provider access, and achievement of quality
281
measures.50 In order to duplicate these physician outcomes, primary care practices newly adopting CMM
282
should ensure pharmacist CMM services meet the individual needs of the physician practice and are
283
integrated into the practice as a collaborative care model, not a separate, isolated function.
284 285
Widespread adoption of robust, pharmacist-delivered CMM care models in primary care settings can help
286
further transition the U.S. healthcare system into one that is patient-centric, holistic, and focused on value.
287
Through implementation of CMM services, pharmacists can work alongside physicians in medical home
288
models, play a vital role in the transition to value-based care, and enhance the success of the growing
289
number of primary care practices engaged in value-based models.
290 291
Limitations
292
There are a few limitations to this study. First, publicly-available information regarding commercial
293
contract data between employers and health plans as well as health plans and care practices is very
294
limited. Although the literature suggests that there is an increasing commercial focus on value and quality
295
measures, the magnitude and specifics of this change remains unknown. Second, this study focused on the
296
largest sources of health insurance in the U.S. and therefore, excluded smaller populations with very
297
unique contracts or delivery systems where patients seek care such as the Veterans Affairs (VA) and
298
uninsured patients. Third, this study focuses on the delivery of comprehensive, whole-patient-centered
299
CMM in primary care settings and does not focus on pharmacists providing care in specialty clinics.
300
Specialty-focused pharmacist services are less standardized across practice settings and associations to
301
various financial elements likely vary across individual practices.
302 303 304
CONCLUSIONS
305 306
This study presents a novel framework for justifying the adoption of pharmacist-delivered CMM services
307
in the U.S. By improving healthcare quality measures and decreasing acute complications of chronic
308
disease management, CMM can increase health plan and primary care practice market competitiveness,
309
direct revenue, and achievement of quality bonuses. The broad alignment of benefits that can be realized
310
across the healthcare system provides a strong value proposition for greater adoption of CMM services in
311
the U.S. primary health care system.
312 313
Funding Source: This research did not receive any specific grant from funding agencies in the public,
314
commercial, or not-for-profit sectors.
315 316
Competing Interests: The authors have no competing interests to disclose.
317
REFERENCES 1.
2. 3.
4.
5.
6.
7. 8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Centers for Medicare & Medicaid Services. National health expenditure fact sheet. https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-andReports/NationalHealthExpendData/NHE-Fact-Sheet.html. Published 2018. Accessed 04.07.18. Watanabe JH, McInnis T, Hirsch JD. Cost of prescription drug–related morbidity and mortality. Ann Pharmacother. March 2018;52:829-837. doi:10.1177/1060028018765159 Roth McClurg M, Sorensen TD, Carroll J, et al. The patient care process for delivering Comprehensive Medication Management (CMM): optimizing medication use in patient-centered, team-based care; 2018. http://www.accp.com/cmm_care_process. Accessed 11.03.19. Westberg SM, Derr SK, Weinhandl ED, et al. Drug therapy problems identified by pharmacists through Comprehensive Medication Management following hospital discharge. J Pharm Technol. 2017;33:96-107. doi:10.1177/8755122517698975 Shimp LA, Kucukarslan SN, Elder J, et al. Employer-based patient-centered medication therapy management program: evidence and recommendations for future programs. J Am Pharm Assoc (2003). 2012;52:768-776. doi:10.1331/JAPhA.2012.11186 Ramalho de Oliveira D, Brummel AR, Miller DB, et al. Medication Therapy Management: 10 years of experience in a large integrated health care system. J Manag Care Pharm. 2010;16:185195. doi:10.18553/jmcp.2010.16.3.185 Isetts BJ. Evaluating effectiveness of the Minnesota Medication Therapy Management care program; 2007. https://www.leg.state.mn.us/docs/2008/mandated/080113.pdf. Accessed 03.02.18. Isetts BJ, Brummel AR, de Oliveira DR, et al. Managing drug-related morbidity and mortality in the patient-centered medical home. Med Care. 2012;50:997-1001. doi:10.1097/MLR.0b013e31826ecf9a Altavela JL, Jones MK, Ritter M. A prospective trial of a clinical pharmacy intervention in a primary care practice in a capitated payment system. J Manag Care Pharm. 2008;14:831-843. doi:10.18553/jmcp.2008.14.9.831 Truong H-A, Groves CN, Congdon HB, et al. Potential cost savings of medication therapy management in safety-net clinics. J Am Pharm Assoc. 2015;55:269-272. doi:10.1331/JAPhA.2015.14062 Woodall T, Landis SE, Galvin SL, et al. Provision of annual wellness visits with comprehensive medication management by a clinical pharmacist practitioner. Am J Heal Pharm. 2017;74:218223. doi:10.2146/ajhp150938 Roth MT, Ivey JL, Esserman DA, et al. Individualized medication assessment and planning: Optimizing medication use in older adults in the primary care setting. Pharmacotherapy. 2013;33:787-797. doi:10.1002/phar.1274 Smith M, Giuliano MR, Starkowski MP. In Connecticut: improving patient medication management in primary care. Health Aff (Millwood). 2011;30:646-654. doi:10.1377/hlthaff.2011.0002 Isetts BJ, Schondelmeyer SW, Artz MB, et al. Clinical and economic outcomes of medication therapy management services: the Minnesota experience. J Am Pharm Assoc. 2008;48:203-211. doi:10.1331/JAPhA.2008.07108 Rothman RL, Malone R, Bryant B, et al. A randomized trial of a primary care-based disease management program to improve cardiovascular risk factors and glycated hemoglobin levels in patients with diabetes. Am J Med. 2005;118:276-284. doi:10.1016/j.amjmed.2004.09.017 Brummel AR, Soliman AM, Carlson AM, et al. Optimal diabetes care outcomes following face-toface medication therapy management services. Popul Health Manag. 2013;16:28-34. doi:10.1089/pop.2012.0023 McAdam-Marx C, Dahal A, Jennings B, et al. The effect of a diabetes collaborative care management program on clinical and economic outcomes in patients with type 2 diabetes. J Manag care Spec Pharm. 2015;21:452-468. doi:10.18553/jmcp.2015.21.6.452
18.
19. 20. 21. 22.
23. 24.
25. 26.
27.
28. 29.
30.
31.
32.
33.
34.
35.
Chung N, Rascati K, Lopez D, et al. Impact of a clinical pharmacy program on changes in hemoglobin A1c, diabetes-related hospitalizations, and diabetes-related emergency department visits for patients with diabetes in an underserved population. J Manag care Spec Pharm. 2014;20:914-919. doi:10.18553/jmcp.2014.20.9.914 Ip EJ, Shah BM, Yu J, et al. Enhancing diabetes care by adding a pharmacist to the primary care team. Am J Health Syst Pharm. 2013;70:877-886. doi:10.2146/ajhp120238 Viswanathan M, Kahwati LC, Golin CE, et al. Medication Therapy Management interventions in outpatient settings. JAMA Intern Med. 2015;175:76. doi:10.1001/jamainternmed.2014.5841 Chisholm-Burns MA, Kim Lee J, Spivey CA, et al. US pharmacistsʼ effect as team members on patient care. Med Care. 2010;48:923-933. doi:10.1097/MLR.0b013e3181e57962 Centers for Medicare & Medicaid Services. Medication Therapy Management in a chronically ill population: final report; 2010. https://innovation.cms.gov/files/reports/mtm_final_report.pdf. Accessed 04.08.18. Centers for Medicare & Medicaid Services. Evidence supporting enhanced Medication Therapy Management. https://innovation.cms.gov/Files/x/mtm-evidencebase.pdf. Accessed 04.08.18. Romanelli RJ, Leahy A, Jukes T, et al. Pharmacist-led medication management program within a patient-centered medical home. Am J Health Syst Pharm. 2015;72:453-459. doi:10.2146/ajhp140487 Smith M, Bates DW, Bodenheimer TS. Pharmacists belong in Accountable Care Organizations and integrated care teams. Health Aff. 2013;32:1963-1970. doi:10.1377/hlthaff.2013.0542 Brummel A, Lustig A, Westrich K, et al. Best practices: improving patient outcomes and costs in an ACO through comprehensive medication therapy management. J Manag care Spec Pharm. 2014;20:1152-1158. Kaiser Family Foundation. Employer health benefits 2017 annual survey; 2017. http://files.kff.org/attachment/Report-Employer-Health-Benefits-Annual-Survey-2017. Accessed 04.05.2018. Barnett JC, Berchick ER. Health Insurance Coverage in the United States: 2016; 2017. https://www.census.gov/library/publications/2017/demo/p60-260.html. Accessed 02.23.18. Kaiser Family Foundation. Medicare Advantage 2017 spotlight: enrollment market update; 2017. https://www.kff.org/medicare/issue-brief/medicare-advantage-2017-spotlight-enrollment-marketupdate/. Accessed 04.06.18. National Governor’s Association. The expanding role of pharmacists in a transformed health care system; 2015. https://web.archive.org/web/20150121231715/http://www.nga.org/files/live/sites/NGA/files/pdf/2 015/1501TheExpandingRoleOfPharmacists.pdf. Accessed 04.09.18. U.S. Public Health Service, Office of the Chief Pharmacist. Improving patient and health system outcomes through advanced pharmacy practice: a report to the U.S. Surgeon General; 2011. https://www.accp.com/docs/positions/misc/improving_patient_and_health_system_outcomes.pdf. Accessed 05.28.19. Medicare Payment Advisory Commission. Medicare Advantage program payment system; 2016. http://www.medpac.gov/docs/default-source/paymentbasics/medpac_payment_basics_16_ma_final.pdf. Accessed 04.06.18. National Committee for Quality Assurance. NCQA health insurance plan ratings 2018. http://www.ncqa.org/report-cards/health-plans/health-insurance-plan-ratings/ncqa-healthinsurance-plan-ratings-2018. Accessed 04.06.18. National Committee for Quality Assurance. NCQA health insurance plan ratings methodology, July 2018. https://www.ncqa.org/wpcontent/uploads/2018/09/201808013_Health_Plan_Ratings_Methodology.pdf. Accessed 04.06.18. National Committee for Quality Assurance. HEDIS 2018 meeasures: summary table of measures, product lines, and changes. http://www.ncqa.org/Portals/0/HEDISQM/HEDIS2018/HEDIS 2018 Measures.pdf?ver=2017-06-28-134644-370. Accessed 04.06.18.
36.
37.
38.
39.
40.
41.
42. 43. 44.
45.
46.
47.
48. 49.
50.
Centers for Medicare and Medicaid Services. 2018 Part C & D Star Ratings Measures; 2018. https://www.cms.gov/Medicare/Prescription-DrugCoverage/PrescriptionDrugCovGenIn/Downloads/2018MeasureList.pdf. Accessed 04.06.18. Milliman Foundation. Grzeskowiak D. Medicare Advantage Star Ratings: basics and best practices; 2017. http://www.milliman.com/uploadedFiles/insight/2017/medicare-advantage-starratings-best-practices.pdf. Accessed 04.06.18. Medicaid and CHIP Payment and Access Commission. Report to the Congress: The evolution of managed care in Medicaid; 2011. https://www.macpac.gov/wpcontent/uploads/2015/01/Payment_Policy_in_Medicaid_Managed_Care.pdf. Accessed 04.06.18. National Committee for Quality Assurance. NCQA PCMH Standards and Guideline; 2017. http://store.ncqa.org/index.php/catalog/product/view/id/2776/s/2017-pcmh-standards-andguidelines-epub/. Accessed 04.07.18. Centers for Medicare and Medicaid Services. Physician Fee Schedule Search. https://www.cms.gov/apps/physician-fee-schedule/search/searchresults.aspx?Y=0&T=0&HT=0&CT=3&H1=99495&M=5. Accessed 04.07.18. American Society of Health System Pharmicsts (ASHP). Pharmacist billing for ambulatory pharmacy patient care services in a physician- based clinic and other non-hospital-based environments – FAQ; 2014. https://www.ashp.org/-/media/assets/ambulatory-carepractitioner/docs/sacp-pharmacist-billing-for-ambulatory-pharmacy-patient-care-services.pdf. Accessed 04.05.18. Ulrich IP, Patel S, Gilmer B. Evaluation of a pharmacist–physician covisit model in a family medicine practice. J Am Pharm Assoc. 2018; 59:129-135.. doi:10.1016/J.JAPH.2018.09.010 Centers for Medicare and Medicaid Services. Comprehensive Primary Care Plus; 2018. https://innovation.cms.gov/initiatives/comprehensive-primary-care-plus. Accessed 04.07.18. Patient-Centered Primary Care Collaborative (PCPCC). Benefits of implementing the primary care patient-centered medical home: A review of cost & quality results; 2012. https://www.pcpcc.org/sites/default/files/media/benefits_of_implementing_the_primary_care_pcm h.pdf. Accessed 03.23.18. Brummel A, Lustig A, Westrich K, et al. Best practices: improving patient outcomes and costs in an ACO through comprehensive medication therapy management. J Manag care Spec Pharm. 2014;20:1152-1158. Friedberg M, Chen P, White C, et al. Effects of health care payment models on physician practice in the United States. RAND. 2015. http://130.154.3.8/content/dam/rand/pubs/research_reports/RR800/RR869/RAND_RR869.pdf. Accessed 02.02.17. Centers for Medicare and Medicaid Services. The Merit-Based Incentive Payment System: MIPS scoring methodology overview. https://www.cms.gov/Medicare/Quality-Initiatives-PatientAssessment-Instruments/Value-Based-Programs/MACRA-MIPS-and-APMs/MIPS-ScoringMethodology-slide-deck.pdf. Accessed 04.07.18. Centers for Medicare and Medicaid Services. MIPS Quality Measures. https://qpp.cms.gov/mips/quality-measures. Accessed 04.07.18. American Society of Health-System Pharmacists. SNOMED CT Codes: Making the case for pharmacy services with hard data; 2015. https://www.ashpintersections.org/2015/02/snomed-ctcodes-making-the-case-for-pharmacy-services-with-hard-data/. Accessed 04.08.18. Funk KA, Pestka DL, Mcclurg MTR, et al. Primary care providers believe that Comprehensive Medication Management improves their work-life. J Am Board Fam Med. 2019;32:462-473. doi:10.3122/jabfm.2019.04.180376
Figure 1. Conceptual framework describing the economic value proposition for CMM within the U.S. healthcare system.
Abbreviations: ACO = accountable care organization, FFS = fee for service, MA = Medicare Advantage, MIPS = Merit-Based Incentive Payment System, NCQA = National Committee for Quality Assurance, P4P = pay for performance, PCMH = patient centered medical home, TPA = thirdparty administrator.
Table 1. 2018 Medicare STAR measures influenced by pharmacist CMM services. Annual flu vaccine Care for Older Adults – Medication Review Controlling Blood Pressure Diabetes Care - Blood Sugar Controlled Getting Needed Prescription Drugs Improving Bladder Control Medication Adherence for Diabetes Medications Medication Adherence for Hypertension (RAS antagonists) Medication Adherence for Cholesterol (Statins) Medication Reconciliation Post-Discharge MTM Program Completion Rate for CMR Osteoporosis Management in Women who had a Fracture Plan All-Cause Readmissions Reducing the Risk of Falling Rheumatoid Arthritis Management Abbreviations: CMR = comprehensive medication review, MTM = Medication Therapy Management, RAS = renin-angiotensin system Table 2. Billing codes related to CMM services. HCPCS Code Description Code CPT 99211
2018 Reimbursement Fee Schedule $22
Evaluation and management service office or other outpatient visit that may not require the presence of a physician CPT 99490 Chronic care management service – 20 $42 minutes CPT 99495 Transitional care management – 14-day $167 discharge CPT 99456 Transitional care management – 7-day $236 discharge G0438 Annual Wellness Visit – initial visit $175 G0439 Annual Wellness Visit – subsequent visit $119 Abbreviations: CPT = Current Procedural Terminology, HCPCS = Healthcare Common Procedure Coding System