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MANAGEMENT OF PREGNANT PATIENT WITH MANDIBULAR INJURY
ABSTRACTS
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Lymphoepithelial lesions were also present. Immunohistochemistry showed positivity for LCA and CD20. Negative reactions against CD3, CD10, CD23, CD43, and cyclin D1 were also seen. The proliferative index measured by Ki67 expression was very low. The clinical, microscopic, and immunohistochemical data led to the diagnosis of MALT lymphoma. The patient received surgical therapy and is free of lesions.
ORAL MANIFESTATION OF WEGENER GRANULOMATOSIS: CASE REPORT. GISELE ^A CORRE DE OLIVEIRA, FERNANDA BROCHIER CARDOSO, LUAN NATHIEL SANTANA KOVALSKI, VINICIUS COELHO CARRARD, MICHELLE ROXO GONCALVES, ¸ JULIANA ROMANINI and, MARCO ANTONIO TREVIZANI MARTINS An 86-year-old man was evaluated complaining a painful lesion situated in the tongue with 45-day duration. Medical history revealed anemia, heart disease, vasculitis, and glomerulitis associated with the previous diagnosis of Wegener granulomatosis. Positive reaction for antineutrophil cytoplasmic autoantibodies (ANCA) was reported. Intraoral examination revealed an asymptomatic ulceration on the dorsum of the tongue surrounded by a whitish area that measures its 2.0 £ 1.0 cm in its largest diameters. Clinical hypotheses were Wegener granulomatosis (GW), fungal infection, or bacterial infection. Incisional biopsy was performed, and the histopathologic diagnosis was an unspecific ulceration. The study of BAAR (alcohol - resistant acid bacillus) and fungal infection were negative. The treatment consisted of topical corticosteroids (clobetasol), oral hygiene guidelines, and photobiomodulation with the diode laser. Lesion completely regressed in 60 days.
OSTEOSARCOMA OF THE JAWS: CLINICOPATHOLOGIC STUDY OF 3 CASES. ANDRE MYLLER BARBOSA SILVA, OSLEI PAES DE ALMEIDA, PABLO AGUSTIN VARGAS, LUCAS LACERDA DE SOUZA, FLAVIA SIROTHEAU CORREA ^ PONTES, HELDER ANTONIO REBELO PONTES and, FELIPE PAIVA FONSECA Osteosarcoma is the most frequent primary malignant bone tumor, but osteosarcomas of the jaws are uncommon and account for only 2% to 10% of all cases diagnosed. The aim of this study is to present 3 new cases of osteosarcoma affecting the gnathic bones. The mandible was affected in 2 cases, whereas the maxilla was involved in 1. Age ranged from 10 to 25 years, and all patients were female. An asymptomatic expansive swelling was the chief complaint in all cases. Microscopically, a diffuse proliferation of pleomorphic cells with presence of osteoid material and variable number of atypical mitotic features were observed. Ki67 staining showed a proliferative index of approximately 15%, and positivity for D2-40 and CDK4 were also observed. All patients are currently under oncological treatment. Support: FAPEMIG.
MANAGEMENT OF PREGNANT PATIENT WITH MANDIBULAR INJURY. EVA AGUIAR ALMEIDA CAMPOS CASTRO TORRIANI, LUISA BERLATO, VICTOR DE MELLO PALMA and, CRISTIANE CADEMARTORI DANESI The management of pregnant women in dentistry is a challenge that requires attention and interdisciplinary care. This study
OOOO January 2020 reports the case of mandibular intraosseous lesion in pregnant women, addressing tomographic dose, type of anesthetic procedure, moment of intervention, and outcome of treatment. The patient is 44 years old with complaint of lack of sensitivity in the mental region. She was on the third gestational month, and had done cone beam tomography. Clinical examination revealed a slight increase in mandibular volume, absence of decayed teeth, or periodontal pocket in the involved teeth. After contact with the attending physician, an incisional biopsy was performed with 2% lidocaine with epinephrine, with diagnostic hypotheses of Central giant cell granuloma (CGCG), ameloblastoma, and aneurysmal bone cyst. After definitive diagnosis of CGCG, we chose to perform surgical treatment after childbirth. The patient returned 1 year later, and the lesion spontaneously regressed. After 2 years, computed tomography showed total wound healing.
DIFFUSE LARGE B-CELL LYMPHOMA IN THE e UPPER LIP: CASE REPORT. GEORGE JOAO FERREIRA DO NASCIMENTO, INGRIDY CRISTINY DE SOUSA MOREIRA, MARIA DE FATIMA, MARIA DE FATIMA VIEIRA ALVES, ANA PAULA VERAS SOBRAL, LEORIK PEREIRA DA SILVA, KEILA MARTHA AMORIM BARROSO and, CYNTIA HELENA PEREIRA DE CARVALHO Diffuse large B-cell lymphomas (DLBCLs) are uncommon in the mouth; however, they are the commonest type of nonHodgkin lymphomas at this site. Preferentially, they affect tonsils and their occurrence in the upper lip is rare. This work reports a case of DLBCL arising in the left upper lip of a 73year-old white woman that was recently diagnosed as having advanced breast cancer besides being a carrier of Parkinson and Alzheimer diseases. The mucosal surface of the upper lip displayed a solitary, fast-growing, painful, ulcerated, reddish, and sessile 4-cm-sized swelling without cervical lymph node involvement at presentation. After incisional biopsy, the microscopic analysis showed a lymphoid cell malignant neoplasm presenting great amounts of large-to-medium sized cells resembling centroblasts losing cell cohesion. Immunohistochemical profile was intensely positive for CD20 and Ki-67, diffusely positive for CD3, and negative for pan-cytokeratins. Unfortunately, the patient died 2 weeks after our clinical care before receiving her final diagnosis.
ORAL MANIFESTATIONS OF SCLERODERMA - CASE REPORT. FABIANE MARQUES DOS SANTOS FREIRE, KELLY TAMBASCO BEZERRA, NATHALIA SCHETTINI SETUBAL FERME, VALDIR MEIRELLES JUNIOR, MARCIA GRILLO CABRAL, JOSE ALEXANDRE DA ROCHA CURVELO and, MARIA ELISA RANGEL JANINI Scleroderma is a rare autoimmune disease of unknown etiology characterized by the acumination of collagen in the tissues, which can be divided into localized and systemic. The localized one occurs more in the skin and rarely intraorally. Patient M.S. O., 45 years old and white, was referred to the stomatology clinic presenting painful symptomatology on the left side palate. In her anamnesis, she reported fibromyalgia. Intraoral examination revealed leukoplastic plaques on the palate in a "saber-throb" pattern and the tongue. Use of Omcilon-A orabase was indicated without regression of the condition. Prescription prednisone 20 mg, 1 tablet/d was applied. After 3 days, regression of 80% of
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Lymphoepithelial lesions were also present. Immunohistochemistry showed positivity for LCA and CD20. Negative reactions against CD3, CD10, CD23, CD43, and cyclin D1 were also seen. The proliferative index measured by Ki67 expression was very low. The clinical, microscopic, and immunohistochemical data led to the diagnosis of MALT lymphoma. The patient received surgical therapy and is free of lesions.
ORAL MANIFESTATION OF WEGENER GRANULOMATOSIS: CASE REPORT. GISELE ^A CORRE DE OLIVEIRA, FERNANDA BROCHIER CARDOSO, LUAN NATHIEL SANTANA KOVALSKI, VINICIUS COELHO CARRARD, MICHELLE ROXO GONCALVES, ¸ JULIANA ROMANINI and, MARCO ANTONIO TREVIZANI MARTINS An 86-year-old man was evaluated complaining a painful lesion situated in the tongue with 45-day duration. Medical history revealed anemia, heart disease, vasculitis, and glomerulitis associated with the previous diagnosis of Wegener granulomatosis. Positive reaction for antineutrophil cytoplasmic autoantibodies (ANCA) was reported. Intraoral examination revealed an asymptomatic ulceration on the dorsum of the tongue surrounded by a whitish area that measures its 2.0 £ 1.0 cm in its largest diameters. Clinical hypotheses were Wegener granulomatosis (GW), fungal infection, or bacterial infection. Incisional biopsy was performed, and the histopathologic diagnosis was an unspecific ulceration. The study of BAAR (alcohol - resistant acid bacillus) and fungal infection were negative. The treatment consisted of topical corticosteroids (clobetasol), oral hygiene guidelines, and photobiomodulation with the diode laser. Lesion completely regressed in 60 days.
OSTEOSARCOMA OF THE JAWS: CLINICOPATHOLOGIC STUDY OF 3 CASES. ANDRE MYLLER BARBOSA SILVA, OSLEI PAES DE ALMEIDA, PABLO AGUSTIN VARGAS, LUCAS LACERDA DE SOUZA, FLAVIA SIROTHEAU CORREA ^ PONTES, HELDER ANTONIO REBELO PONTES and, FELIPE PAIVA FONSECA Osteosarcoma is the most frequent primary malignant bone tumor, but osteosarcomas of the jaws are uncommon and account for only 2% to 10% of all cases diagnosed. The aim of this study is to present 3 new cases of osteosarcoma affecting the gnathic bones. The mandible was affected in 2 cases, whereas the maxilla was involved in 1. Age ranged from 10 to 25 years, and all patients were female. An asymptomatic expansive swelling was the chief complaint in all cases. Microscopically, a diffuse proliferation of pleomorphic cells with presence of osteoid material and variable number of atypical mitotic features were observed. Ki67 staining showed a proliferative index of approximately 15%, and positivity for D2-40 and CDK4 were also observed. All patients are currently under oncological treatment. Support: FAPEMIG.
MANAGEMENT OF PREGNANT PATIENT WITH MANDIBULAR INJURY. EVA AGUIAR ALMEIDA CAMPOS CASTRO TORRIANI, LUISA BERLATO, VICTOR DE MELLO PALMA and, CRISTIANE CADEMARTORI DANESI The management of pregnant women in dentistry is a challenge that requires attention and interdisciplinary care. This study
OOOO January 2020 reports the case of mandibular intraosseous lesion in pregnant women, addressing tomographic dose, type of anesthetic procedure, moment of intervention, and outcome of treatment. The patient is 44 years old with complaint of lack of sensitivity in the mental region. She was on the third gestational month, and had done cone beam tomography. Clinical examination revealed a slight increase in mandibular volume, absence of decayed teeth, or periodontal pocket in the involved teeth. After contact with the attending physician, an incisional biopsy was performed with 2% lidocaine with epinephrine, with diagnostic hypotheses of Central giant cell granuloma (CGCG), ameloblastoma, and aneurysmal bone cyst. After definitive diagnosis of CGCG, we chose to perform surgical treatment after childbirth. The patient returned 1 year later, and the lesion spontaneously regressed. After 2 years, computed tomography showed total wound healing.
DIFFUSE LARGE B-CELL LYMPHOMA IN THE e UPPER LIP: CASE REPORT. GEORGE JOAO FERREIRA DO NASCIMENTO, INGRIDY CRISTINY DE SOUSA MOREIRA, MARIA DE FATIMA, MARIA DE FATIMA VIEIRA ALVES, ANA PAULA VERAS SOBRAL, LEORIK PEREIRA DA SILVA, KEILA MARTHA AMORIM BARROSO and, CYNTIA HELENA PEREIRA DE CARVALHO Diffuse large B-cell lymphomas (DLBCLs) are uncommon in the mouth; however, they are the commonest type of nonHodgkin lymphomas at this site. Preferentially, they affect tonsils and their occurrence in the upper lip is rare. This work reports a case of DLBCL arising in the left upper lip of a 73year-old white woman that was recently diagnosed as having advanced breast cancer besides being a carrier of Parkinson and Alzheimer diseases. The mucosal surface of the upper lip displayed a solitary, fast-growing, painful, ulcerated, reddish, and sessile 4-cm-sized swelling without cervical lymph node involvement at presentation. After incisional biopsy, the microscopic analysis showed a lymphoid cell malignant neoplasm presenting great amounts of large-to-medium sized cells resembling centroblasts losing cell cohesion. Immunohistochemical profile was intensely positive for CD20 and Ki-67, diffusely positive for CD3, and negative for pan-cytokeratins. Unfortunately, the patient died 2 weeks after our clinical care before receiving her final diagnosis.
ORAL MANIFESTATIONS OF SCLERODERMA - CASE REPORT. FABIANE MARQUES DOS SANTOS FREIRE, KELLY TAMBASCO BEZERRA, NATHALIA SCHETTINI SETUBAL FERME, VALDIR MEIRELLES JUNIOR, MARCIA GRILLO CABRAL, JOSE ALEXANDRE DA ROCHA CURVELO and, MARIA ELISA RANGEL JANINI Scleroderma is a rare autoimmune disease of unknown etiology characterized by the acumination of collagen in the tissues, which can be divided into localized and systemic. The localized one occurs more in the skin and rarely intraorally. Patient M.S. O., 45 years old and white, was referred to the stomatology clinic presenting painful symptomatology on the left side palate. In her anamnesis, she reported fibromyalgia. Intraoral examination revealed leukoplastic plaques on the palate in a "saber-throb" pattern and the tongue. Use of Omcilon-A orabase was indicated without regression of the condition. Prescription prednisone 20 mg, 1 tablet/d was applied. After 3 days, regression of 80% of