INTERNATIONAL ABSTRACTS Seven had a neurological problem. All procedures were performed under general anesthesia, 47 electively. The technique varied with the speciality of the surgeon (pediatric, ENT, or cardiac). A transverse skin incision was used in most cases, the trachea being opened either vertically or transversely. Early complications occurred in a third of patients. These included tube obstruction, pneumothorax, emphysema, hemorrhage, granulations, extubation difficulty, tube in bronchus, and pneumomediastinum. Seven developed late complications after extubation. These were stenosis, strider, tracheomalacia, and cutaneous fistula. There were 26 deaths due to the primary condition, none due to the tracheostomy. The technique of tracheostomy did not influence the results. The authors conclude that the increased use of mechanical ventilation in small babies with respiratory impairment is a major factor in influencing the use of tracheostomy.--W.G. Scobie
87 eight patients had normal forced expiratory volume of 72% of vital capacity and were included in the study. The patients were divided into groups by age at pneumonectomy. The ventilatory capacity was not dissimilar from that predicted for two lungs in those patients undergoing surgery from 0 to 5 years of age, confirming that near complete compensation had occurred. This may be due to continuing alveolar multiplication. The compensatory ability of the lung decreases with age. Hyperplasia or simple hypertrophy may be responsible for postoperative growth in the older age groups (>6 years of age). These compensatory changes have extended into the long-terra. Of note is the finding that normal growth in height occurred in children following pneumonectomy.--Marleta Reynolds
Pleural Empyema in Children: A Nationwide Retrospective Study. Plunging Ranula: A Report of Three Cases and Review of the Literature, D. Parekh, M. Stewart, C. Joseph, et al. Br J Surg
74:307-309, (April), 1987. Three patients (aged 15 to 20 years) with plunging ranulas who were successfully treated by excision of the sublingual and submandibular glands using a cervical incision are reported. In a review of the literature, the high recurrence rate (70%) following various procedures is noted. The authors conclude that the cervical component is due to high pressure causing extravasation of the saliva in an oral ranula through a hiatus in the mylohyoid muscle, and that intraoral excision of the sublingual gland with intraoral drainage is adequate treatment; this contrasts with the surgical approach used in the three cases they report.--N.P. Madden THORAX Aggressive Surgical Approach for Drug-Free Remission From Myasthenia Gravis, J.E. Fischer, H.T. Grisvalski, M.S. Nussbaum,
et al. Ann Surg 205:490-503, (May), 1987 Myasthenia gravis is believed to be an autoimmune disease in which antibodies to acetylcholine receptors are produced by subsets of T-lymphoeytes. It affects all ages and both sexes, with peaks in the second and fifth decades, with younger females and older males being the most commonly affected. Transsternal wide thymectomy is now considered the treatment of choice. Twenty-seven p~tients aged 6 to 75 years treated by sternal split and extended thymectomy and radical mediastinal dissection are reported. The overall drug-free remission rate was 63% with a projected 74% drug-free remission rate. Of the remaining patients, all but three improved and required decrease medication for an improvement rate of approximately 90%. The mean taper time from start of tapering medications to drug-free remission was 283 days. Thymomas was present in three patients, six patients were believed to have thymic hyperplasia, nine patients had an involuted thymus, two patients a normal thymus, and in seven there was disagreement as to whether thymic hyperplasia was present. There was no relationship between perioperative and postoperative antibodies to acetylcholine receptor levels and the clinical course, nor was there any relationship between the clinical course, the final outcome, and drug-free remission. The results suggest that an aggressive radical surgical approach to myathenia gravis, even in a group of patients considered somewhat less favorable because of a relatively long duration of disease, can result in a high percentage of drug-free remissions.--Richard J. Andrassy Dilatation, Compensatory Growth, or Both After Pneumonectomy During Childhood and Adolescence. A Thirty Year Follow-up
Study. C.D. Lares and C.J.J. Westerman. J Thorac Cardiovase Surg 93:570-576, (April), 1987. Ventilatory function was evaluated in a total of 230 patients who had undergone pneumonectomy more than 30 years ago. Ninety-
J.E. Fajardo and M.J. Chang. South Med J 80:593-596, (May), 1987. The most common causative agents in the production of empyema in the 1940s were Streptococcus pneumoniae and Streptococcus pyogenes. In the 1950s Staphylococcus aureus became the causative agent of 92% of cases of empyema in childhood. Military hospitals across the United States provided data for this retrospective study on pediatric patients with empyema. No organism was isolated either from blood or pleural fluid in 49 of the 104 (47%) patients reviewed. Of the remaining 55 children, a positive blood culture provided the etiologic diagnosis in 14% and pleural fluid culture was positive in 27%. In 9%, organisms grew from both the blood and the pleural fluid cultures. In 3% the etiologic diagnosis was based on positive counterimmunoelectrophoresis. Hemophilus influenzae type b (17%), Streptococcus pneumoniae (14%), and Staphylococcus aureus (11%) were the most common etiologic agents. Pneumonia was the most common predisposing factor, occurring in 62%. Empyema was related to an operation in 12 patients. There were no cases of primary staphylococcal pneumonia, and all patients who developed staphylococcal empyema did so as a result of abscesses, osteomyelitis, surgery, physical trauma, or burns.--George Holcomb, Jr
Management of Tracheomalacia by Aortopexy. E.M. Kiely, L. Spitz, and R. Brereton. Pediatr Surg Internal 2:13-15, (January), 1987.
Over a 6.5-year period, 25 infants and children with symptomatic tracheomalacia underwent aortopexy. Seventeen of the patients had immediate and dramatic relief of symptoms and five others were greatly improved. The operation failed in one patient who required two subsequent procedures. Early recourse to aortopexy is recommended when symptoms of tracheomalacia become evident.--Prem Purl
HEART AND GREAT VESSELS Operative Closure of Patent Ductus Arteriosus in Premature Infants in the Neonatal Intensive Care Unit, R.L. Taylor, F.L.
Gover, P.K. Harman, et al. Am J Surg 152:704-708 (December), 1986. Operative closure of a PDA may still be the therapy of choice at certain institutions due to increasing recognition of complications associated with the use of indomethaein. There were 52 consecutive infants who underwent thoracotomy and ductus closure on the MICU with a ligaclip. There were no deaths and only nine operative complications. Operative closure was effected in a mean time of three days after diagnosis. Early operative closure is recommended.--Thomas V. Whalen