Manuscript descriptor form

MANUSCRIPT DESCRIPTOR FORM Describe the type of manuscript you are submitting by listing in order of importance three relevant descriptor numbers here:

AGA DESCRIPTORS: Clinical Practice 01 Clinical Management Strategies 02 Epidemiology 03 Health Policy/Technology Assessment/Health Services Research 04 Practice Management & Quality Assurance

Esophageal, Gastric, and Duodenal Disorders 05 Secretion: Mechanisms and Regulation 06 Mucosal Repair and Healing 07 Experimental Mucosal Lesions 08 Helicobacter pylori: Epidemiology & Pathogenesis 09 Helicobacter pylori: Diagnosis & Treatment 10 Acid/Peptic (Includes NSAIDs): Epidemiology & Pathogenesis 11 Acid/Peptic (Includes NSAIDs): Diagnosis, Complications, Treatment 12 Reflux Esophagitis 13 Clinical Esophageal Disorders (Nonreflux)

Intestinal Disorders 14 Pathophysiology of Diarrheal Disorders 15 Malabsorption/Gas 16 Epithelial Nutrient/Salt/Water Transport 17 Regulation of Transport 18 Enterocyte Cell & Molecular Biology 19 Splanchnic Circulation—All Organs 20 Intestinal Bleeding

Pancreatic Disorders 21 Acinar Cell Function 22 Duct Cell Function 23 Receptors/Receptor Action 24 Neurohormonal Control 25 Experimental Pancreatitis 26 Acute Pancreatitis 27 Chronic Pancreatitis 28 Exocrine/Endocrine Tumors

Biliary Disorders 29 Biliary Stone Disease: Nonsurgical Therapy 30 Biliary Stone Disease: Surgical & Endoscopic 31 Gallstones: Chemical, Physical, Mechanical, Radiological Properties 32 Biliary Tract Imaging: Biliary Tract Endoscopy 33 Biliary Tract Motility; Sphincter of Oddi 34 Biliary Disease: Other

1. 2. 3.

Gastrointestinal Oncology

Hormones and Receptors

35 Cell & Molecular Biology/Immunology/ Genetics 36 Proliferation/Carcinogenesis 37 Screening/Diagnosis/Prognosis 38 Prevention/Treatment/Experimental Therapeutics 39 General Clinical/Epidemiology

73 Physiology/Cell Biology/Biochemistry 74 Receptor Characterization/Regulation 75 Molecular Biology 76 Biochemistry 77 Neurobiology, Neurotransmitters and Signaling 78 Biology of Growth/Proliferation/Growth Factors 79 Brain-Gut Axis 80 Clinical Disorders 81 Miscellaneous

Motility and Nerve-Gut Interactions 40 Receptors/Channels/Intracellular Signals/Contraction/Relaxation 41 Intrinsic & Extrinsic Innervation: Anatomy, Nervous, Physiology, Chemistry 42 Physiology/Pathophysiology/ Pharmacology: Esophagus 43 Physiology/Pathophysiology/ Pharmacology: Stomach 44 Physiology/Pathophysiology/ Pharmacology: Small Bowel 45 Physiology/Pathophysiology/ Pharmacology: Colon & Anorectum 46 Functional GI Disorders: Symptoms, Physiology, Behavior, Epidemiology, Treatment Growth, Development, and Aging 47 Mucosal Growth Factors and Receptors 48 Cell Signaling 49 Intestinal Proliferation, Cell Cycle Regulation and Apoptosis 50 Biology of Intestinal Growth, Adaptation and Repair 51 Growth and Development of Liver and Pancreas 52 Gastrointestinal Development: Physiological and Molecular Mechanisms 53 Development of Mucosal Defense 54 Development of Enteric Nerves and Muscle 55 Transgenic and Knock out Animals 56 Morphogenesis, Organogenesis and Stem Cells 57 Epithelial-Mesenchyme and -Matrix Interactions 58 Gene Structure, Regulation and Expression 59 Pediatric Gastrointestinal Disease 60 Pediatric Liver and Pancreatic Disorders 61 Aging and Gastrointestinal Function: Clinical and Basic 62 Clinical Gastroenterology in the Elderly Immunology, Microbiology, and Inflammatory Disorders 63 Mucosal Immunity 64 Host Defense Mechanisms 65 Inflammation 66 Inflammatory Bowel Disease: Basic 67 Inflammatory Bowel Disease: Therapy 68 Inflammatory Bowel Disease: Clinical Investigation and Epidemiology 69 Gastrointestinal and Hepatic Infections/ Viruses 70 AIDS (Basic and Clinical) 71 Helicobacter pylori (Basic) 72 Microbial and Immune Mediated Injury/ Pathology

Nutrition and Obesity 82 Short Gut Syndrome and Intestinal Transplantation 83 Malabsorption 84 Nutrients and Gut Function: Clinical 85 Nutritional Support and Nutritional Assessment 86 Milk: Human and Non-Human Substitutes 87 Probiotics and Functional Foods 88 Vitamins, Minerals and Micronutrients: Clinical 89 Intestinal Absorption and Nutrient Transport 90 Nutrient and Gut Function: Basic 91 Nutrient Metabolism and Signaling 92 Obesity and Eating Disorders: Clinical 93 Obesity and Satiety: Basic

Liver 94 Morphology, Cancer, Regeneration 95 Molecular & Cell Biology, Collagen, Fibrosis 96 Chronic Hepatitis (Nonviral), Primary Biliary Cirrhosis, Sclerosing Cholangitis, Immunology 97 Hepatitis 98 Ethanol, Nutrition, Metabolism (Including Genetic Disease) 99 Complications of Cirrhosis: Portal Hypertension, Portal Circulation 100 Complications of Cirrhosis: Ascites, Encephalopathy 101 Hepatic & Biliary Bile Acid and Ion Transport Bile Formation & Cholestasis 102 Bile Acids, Bile Acid Synthesis & Metabolism, Bile Lipids & Proteins, Lipoproteins 103 Gallstones, Formation & Treatment; Pathobiology of Gallbladder & Biliary Tree 104 Cell Injury, Hepatoxicity and Pharmacology 105 Transplantation and Hepatobiliary Surgery