Materialogical properties of bone grafting materials containing different ratio of calcium phosphate cement and beta-tricalcium phosphate

339 Conclusion: The adipofascial anterolateral thigh flap is an excellent option for maxillary defects with infratemporal fossa extension. The advantage of this flap is that on mucosalisation it provides a taut surface giving a stable support for the prosthesis, the obliteration of the infratemporal fossa ensures no postoperative trismus and there is minimal donor site morbidity. http://dx.doi.org/10.1016/j.ijom.2017.02.1142 Inferior alveolar nerve regeneration with bifocal distraction osteogenesis in dogs Y. Shogen ∗ , E.T. Isomura, K. Nakagawa, M. Kogo First Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, Osaka, Japan Background: Bifocal distraction osteogenesis has been shown to be a reliable method for reconstructing segmental mandibular defects. However, there are few reports regarding the occurrence of inferior alveolar nerve regeneration during the process of distraction. Objectives: We investigated the possibility of the inferior alveolar nerve regeneration after bifocal distraction osteogenesis procedure. Methods: Using a bifocal distraction osteogenesis method, we produced a 10-mm mandibular defect, including a nerve defect, in each dogs and distracted using a transport disk at a rate of 1 mm/day. The regenerated inferior alveolar nerve was evaluated by histological examination, electrophysiologic analysis and retrograde transportation of horseradish peroxidase (HRP). Findings and Conclusion: On histological examination, although consecutive nerves were observed in all areas, cellular nerve fascicles were seen, consistent with Wallerian degeneration at three and six months in the nerve connection area on the distal side of the transport disc. On electrophysiologic analysis, stable evoked potential measurements were obtained from the nerves at six months. At three and six months, HRP-labelled neurons were observed in the trigeminal ganglion. The number of HRP-labelled neurons in each section increased, while the cell body diameter of HRP-labelled neurons was reduced over time. We found that the inferior alveolar nerve after distraction osteogenesis successfully recovered until peripheral tissue began to function. Although our research is still at the stage of animal experiment, it is considered that it will be possible to apply this method in the future to humans who have the mandibular defects. http://dx.doi.org/10.1016/j.ijom.2017.02.1143 Total and near-total lower lip reconstruction — 20 years experience C.F. Sun ∗ , S. Bai, R.W. Li, Z.F. Xu, W.Y. Duan, F.Y. Liu Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University, Shenyang, Liaoning, China Background: Reconstruction of total and near-total lower lip defects presents a formidable challenge for the reconstructive plastic surgeon. Many methods have been described, and each has its own advantages and disadvantages.

Objectives: Discussing the selection of techniques and reporting our experience of total or near-total lower lip reconstruction. Methods: Over a 20-year period from January 1993 to December 2013, a total of 87 patients underwent total or near-total lower lip reconstruction. Bilateral Yu’s flaps were used in 61 patients, double mental neurovascular V-Y island advancement flaps in 16 patients, bilateral Mutaf’s techniques in four patients, and reconstruction with free radial forearm flaps in 6 other patients. Drooling rating scale and patient and observer scar assessment scale were used to evaluate oral competency and aesthetic outcomes. Findings: All patients underwent single-stage total or near-total lower lip reconstruction successfully. There were no flap failures. Only one patient who accepted the bilateral Yu’s flaps developed microstomia, having difficulty in wearing her dentures postoperatively. Oral competencies were well preserved in other patients, and aesthetic results were satisfactory. Conclusion: Based on our experience, we recommend using the bilateral local techniques or free flap introduced in this article, according to the extent of defects and the patient’s general condition, to achieve a personalised ideal reconstruction of the lower lip. http://dx.doi.org/10.1016/j.ijom.2017.02.1144 Materialogical properties of bone grafting materials containing different ratio of calcium phosphate cement and beta-tricalcium phosphate H. Tanaka ∗ , S. Yamada, H. Aizawa, Y.H. Li, I. Karasawa, N. Yoshimura, F. Nishimaki, H. Kurita Department of Dentistry and Oral Surgery, Aizawa Hospital, Matsumoto, Japan Background: Calcium phosphate cement (CPC) is reported to have excellent biocompatibility and osteoconductivity. And it can be contoured to replace lost bone and restore its original shape. However, it is necessary to improve its slow resorption rate. Combining calcium phosphate cement and porous beta-tricalcium phosphate (␤-TCP) may solve this problem. Objectives: The purpose of this study was to create new bone grafting material containing different ratio of CPC and ␤-TCP and to examine its materialological properties. ® Methods: A commercially available CPC (Cerapaste : NGK ® Spark Plug Co. Ltd, Aichi, Japan) and porous ␤-TCP (Cerabeta : NGK Spark Plug Co. Ltd, Aichi, Japan) were used for this study. Four testing materials with different mixing ratios of CPC and ␤TCP (C0, C30, C50; mixing ratio of ␤-TCP was 0 wt%, 30 wt%, 50 wt% respectively) were constructed. We evaluated the basic properties of each material. Findings: The setting time for the C30 was 15 ± 1.09 min and C50 was 18 ± 1.41 min, which is within the clinically acceptable range. As compared to group C0 (control), compressive strength decreased as the content of ␤-TCP increased, due to higher porosity. In a dipping examination to stain, stain reached at the inside of the sample immediately in C50. Therefore, the formation of the communication pore was suggested. Conclusions: CPC mixed with ␤-TCP has good handling characteristics, sufficient porosity and strength. http://dx.doi.org/10.1016/j.ijom.2017.02.1145