Mechanistic insights into the benefits of multisite pacing in cardiac resynchronization therapy: The importance of electrical substrate and rate of left ventricular activation

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Mechanistic Insights into the Benefits of Multi-Site Pacing in Cardiac Resynchronization Therapy: The Importance of Electrical Substrate and Rate of Left Ventricular Activation Manav Sohal MBBS, Anoop Shetty MD, Steven Niederer PhD, Angela Lee PhD, Zhong Chen MBBS, Tom Jackson MBBS, Jonathan M. Behar MBBS, Simon Claridge MBBS, Julian Bostock PhD FHRS, Eoin Hyde, Reza Razavi MD, Frits Prinzen PhD, C. Aldo Rinaldi MD, FHRS

PII: DOI: Reference:

S1547-5271(15)00894-2 http://dx.doi.org/10.1016/j.hrthm.2015.07.012 HRTHM6355

To appear in:

Heart Rhythm

www.elsevier.com/locate/buildenv

Cite this article as: Manav Sohal MBBS, Anoop Shetty MD, Steven Niederer PhD, Angela Lee PhD, Zhong Chen MBBS, Tom Jackson MBBS, Jonathan M. Behar MBBS, Simon Claridge MBBS, Julian Bostock PhD FHRS, Eoin Hyde, Reza Razavi MD, Frits Prinzen PhD, C.Aldo Rinaldi MD, FHRS, Mechanistic Insights into the Benefits of Multi-Site Pacing in Cardiac Resynchronization Therapy: The Importance of Electrical Substrate and Rate of Left Ventricular Activation, Heart Rhythm, http://dx.doi.org/ 10.1016/j.hrthm.2015.07.012 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Mechanistic insights into the benefits of multisite pacing in cardiac resynchronization therapy: The importance of electrical substrate and rate of left ventricular activation

Mechanistic insights into the benefits of multisite pacing in cardiac resynchronization therapy: The importance of electrical substrate and rate of left ventricular activation

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