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Meningiomas: An Update on Diagnostic and Therapeutic Approaches
Meningiomas
P re f a c e Meningiomas: An Update on Diagnostic and Therapeutic A p p ro a c h e s
Gabriel Zada, MD, MS
Randy L. Jensen, MD, PhD Editors
articles will provide cutting-edge information to improve the care of patients with meningiomas. Gabriel Zada, MD, MS USC Pituitary Center USC Radiosurgery Center Neuro-Oncology and Endoscopic Pituitary/ Skull Base Program Keck School of Medicine of USC 1520 San Pablo Street #3800 Los Angeles, CA 90033, USA Randy L. Jensen, MD, PhD Huntsman Cancer Institute University of Utah 5th Floor CNC 175 North Medical Drive Salt Lake City, UT 84132, USA E-mail addresses: [email protected] (G. Zada) [email protected] (R.L. Jensen)
Neurosurg Clin N Am 27 (2016) xiii http://dx.doi.org/10.1016/j.nec.2016.02.001 1042-3680/16/$ – see front matter Ó 2016 Published by Elsevier Inc.
neurosurgery.theclinics.com
Advances in imaging, diagnostics, and therapeutics have improved the contemporary care of patients with meningiomas. In this issue, we examine emerging advanced neuroimaging techniques, including preoperative characteristics that may predict consistency of meningiomas. Endovascular techniques to reduce risk and improve surgical resection of meningiomas are also examined. New diagnostic modalities, including genomic and epigenomic biomarkers, are emerging to aid molecular classification and even potentially open new avenues of signal pathway blockade. Special meningioma subtypes, including secretory, spinal, and interosseous meningiomas, are discussed, with an emphasis on the unique nature of these tumors. Specialized treatment techniques, such as the minimally invasive, endoscopic, and noninvasive stereotactic radiosurgical methods, are outlined. Finally, management of incidental, atypical, and treatment-refractory meningiomas is explored and controversies outlined. It is hoped that these
P re f a c e Meningiomas: An Update on Diagnostic and Therapeutic A p p ro a c h e s
Gabriel Zada, MD, MS
Randy L. Jensen, MD, PhD Editors
articles will provide cutting-edge information to improve the care of patients with meningiomas. Gabriel Zada, MD, MS USC Pituitary Center USC Radiosurgery Center Neuro-Oncology and Endoscopic Pituitary/ Skull Base Program Keck School of Medicine of USC 1520 San Pablo Street #3800 Los Angeles, CA 90033, USA Randy L. Jensen, MD, PhD Huntsman Cancer Institute University of Utah 5th Floor CNC 175 North Medical Drive Salt Lake City, UT 84132, USA E-mail addresses: [email protected] (G. Zada) [email protected] (R.L. Jensen)
Neurosurg Clin N Am 27 (2016) xiii http://dx.doi.org/10.1016/j.nec.2016.02.001 1042-3680/16/$ – see front matter Ó 2016 Published by Elsevier Inc.
neurosurgery.theclinics.com
Advances in imaging, diagnostics, and therapeutics have improved the contemporary care of patients with meningiomas. In this issue, we examine emerging advanced neuroimaging techniques, including preoperative characteristics that may predict consistency of meningiomas. Endovascular techniques to reduce risk and improve surgical resection of meningiomas are also examined. New diagnostic modalities, including genomic and epigenomic biomarkers, are emerging to aid molecular classification and even potentially open new avenues of signal pathway blockade. Special meningioma subtypes, including secretory, spinal, and interosseous meningiomas, are discussed, with an emphasis on the unique nature of these tumors. Specialized treatment techniques, such as the minimally invasive, endoscopic, and noninvasive stereotactic radiosurgical methods, are outlined. Finally, management of incidental, atypical, and treatment-refractory meningiomas is explored and controversies outlined. It is hoped that these