MENTAL HOSPITALS SERVICE.
936
esteem of the Council. We venture to express the opinion that our medical brethren in Scotland could not do better than support his candidature for another term of office. C. E. DOUGLAS,
We are, yours &c., GEORGE R. LIVINGSTON,
J. B. SIMPSON,
MURRAY B. STEUART,
Kirkcudbright.
Golspie. GEORGE WILLIAMSON, ASHLEY W. MACKINTOSH, JOHN MARNOCH, J. F. CHRISTIE, Aberdeen. D. ELLIOT DICKSON,
Lochgelly.
J. MACDONALD,
Cupar.
JOHN J. WILSON, Anstruther.
G. LOVELL GULLAND, HAROLD J. STILES, ROBERT THIN,
Edinburgh. T. K. MONRO,
W. HERBERT BROWN, Glasgow.
to buy their own butter, their discarded is melted down with dripping for the This strange and complex proceeding would be humorous but for the fact that there are known cases of active tuberculosis in the hospital. Our resources in the treatment of mental disease are few enough, but we should surely use, at least in recoverable cases, those of which we have knowledge, and among them an adequate dietary takes an
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Dumfries.
Cupar.
they prefer Ipatients. margarine
J. P. BROWN,
Campbeltown.
important place.
P. F. MACFARLAN,
Stirling. ROBERT
STIRLING,Perth.
Correspondence.
ROBERT INCH, C.
Gorebridge.
J. W.
DIXON, Hawick.
" Audi alteram partem."
A. J. CAMPBELL,
Duns.
WILLIAM
MCALISTER, Kilmarnock.
P. T. HERRING, DAVID WATERSTON, St. Andrews.
JAMES LAURIE, Greenock.
MENTAL HOSPITALS SERVICE.
CANCER AND SOME OF ITS SIGNIFICANT CHEMICAL REACTIONS. To the Editor
of THE LANCET. THE LANCET of Oct.- 4th Mr. H. Gordon SIR,—In Reeves set out the salient features of the chemical work done on the cancer problem in the physiological laboratory of King’s College, London. There is a distinct parallelism between the work outlined and that initiated by Sir George T. Beatson in 1910 at the Glasgow Royal Cancer Hospital, and it is interesting to note that the work done in Glasgow during the last 10 or 15 years has received a large measure of confirmation from that of Shaw-Mackenzie and
A SATISFACTORY year’s work and several changes of interest are recorded in the annual report of the Reeves. Dorset Mental Hospital for 1923-24. The recoveryIn Reeves’s comnmunication some points of an rate has been high, 39 per cent. on total admissions unsettled nature are brought forward, and I should and 54 per cent. reckoned on total recoverable cases. like to draw attention to these. In the first instance Satisfaction is expressed with the results of the Shaw-Mackenzie is quoted as stating that tissue "open door" system adopted in certain wards ; and utilisation of fats are defective in cancer. the patients are also better classified, 84 are allowed lipolysis In his opinion normal blood serum has an accelerating parole within or outside the grounds, and 17 patients influence on lipoclastic activity, and this activity away on trial have received money allowances. is diminished by the addition to lipase of serum Remarkably few epileptics and general paralytics from a cancerous subject. From this and other findings have been admitted ; the comparative freedom from he concludes that there is a general deficiency in syphilis of rural areas is doubtless the explanation lipolytic control, which deficiency, we presume, in the latter case, but the rarity of epilepsy in Dorset he considers is manifested in the carcinomatons is less readily explicable and is deserving of investigaIf this be so, then one would expect to find There is now an out-patient centre in locality. tion. a lowered, rather than an increased, saturation in Dorchester, conducted by the medical superintendent, the fat of the adipose tissue affected. Instead Dr. G. E. Peachell, where 52 patients have been seen Shaw-Mackenzie and Reeves have found, as we have during its first year of working ; 10 of these recovered, in this research department, that there is an increase 12 were relieved, and 9 were certified and admitted in unsatllration of the adipose tissue invaded by to the hospital. In addition to a resident medical carcinoma. I do not think that the range of variastaff of four members, the hospital possesses a tion in affects to any marked degree lipolytic activity a and has dentist and visiting visiting physician, If anything, an increased in saturation. recently acquired a laboratory assistant (apparently change in the tissues would increase the amount of activity not medically qualified), who has undertaken a large free acid. In a determination of iodine value and varied amount of pathological work, including this fatty free fatty acid would be part of the lipin complex analyses, serological and bacteriological water be evaluated and its associates of glycerol or in connexion with typhoid and dysentery, and the lecithin structural units would be absent from the preparation of vaccines. Among the causes of death ether extract. Thus to the complex there would be appears one case of rupture of a coronary artery, added a substance or substances with comparatively surely worthy of note as an extremely rare occarrence. small molecules and a proportionately high unsaturaThe annual report of the Brighton County Borough tion coefficient. As a result of such an addition due Mental Hospital, Haywards Heath, for 1923 contains to increased lipolytic activity, the iodine value of little but a bare record of changes among the patients, the complex would manifestly be increased. It is staff, and committee, apart from the observations on that teleological basis that we are inclined to made by a Visiting Commissioner, from which alone question the validity of Slaaw -lIackenzie’s observation. Recent research has shown that to simulate as can any idea be obtained of the conditions under which thepatients are living. His report embodies closely as possible " in vivo " conditions the course of certain criticisms, some of which owe their origin to enzyme reactions must be controlled with due attenthe fact that the fabric dates from 1859 ; the tion to the hydrogen-ion concentration. It is obvious, facilities, the lack of which is most severely felt, of course, that, in the test-tube, lipase activity is manifested by a change of pH towards the acid side, are a laboratory, clinical room, operating theatre, verandahs, baths, and an out-patient centre. It is owing to an accumulation of the products of lipolysis. also suggested that male patients should be shaved, In the body, however, there is a delicately adjusted that parole (with money allowance) should be granted mechanism whereby the products of enzyme action more often, and that clothing and diet should be are removed from the sphere of activity as soon as improved in certain respects. It appears that the formed, and, because of this control, a constant ordinary patients’ milk is skimmed to provide betterlevel of hydrogen-ion concentration is maintained for debilitated cases ; meanwhile, the nursing andand enzymic inhibition is frustrated. It will be seen, domestic staff are supplied with margarine, but since, then, that it is difficult to simulate the biotic courses
workto