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METASTATIC CARCINOMA IN THE RETROMOLAR AREA: A CASE REPORT
ORAL AND MAXILLOFACIAL PATHOLOGY e80 Abstracts pharmacologic protocol was established because all evidence suggested a higher risk for developing post-extraction osteoradionecrosis. Platelet-rich fibrin in the extraction sockets and the application of low-level laser to stimulate and accelerate healing were used. No reports of pain or edema were observed and follow-up was carried out regularly. After 4 months, no signs of pathologic alterations were seen and the patient was satisfied and healthy.
CPP131 - METASTATIC CARCINOMA IN THE RETROMOLAR AREA: A CASE REPORT. DEBORAH LÚCIA LIMA DA COSTA, PAULO BENEVIDES DOS SANTOS, ADELAIDE PORTELA, FÁBIO FRANCESCONI, THAÍSE DA ROCHA CAVALCANTI, LUCIANA BOTINELLY MENDONÇA FUJIMOTO, JECONIAS CÂMARA. Oral cavity metastases are extremely rare, and comprise 1% of all mouth malignant neoplasms. A 74-year-old female patient with a history of breast cancer underwent mastectomy with axillary dissection, chemotherapy, and radiotherapy 11 years ago presented in 2014 with a lesion in the scalp diagnosed as metastatic ductal breast carcinoma. In 2015 she presented with an intraoral nodule, sessile, not ulcerated in the retromolar area, and a firm and fixed cervical node. An incisional biopsy of intraoral lesion was performed and histopathologic analysis revealed neoplastic lesion, characterized by proliferation of epithelioid cells arranged to form ductal structures, sometimes with cribriform appearance and diagnosis of metastatic adenocarcinoma. Immunohistochemical analysis showed positivity for cytokeratin 7, GATA-3, and estrogen receptor, thus confirming the diagnosis of metastatic ductal breast carcinoma. The patient is being treated with chemotherapy and radiotherapy for disease control.
CPP132 - VERRUCOUS CARCINOMA AS A CLINICOPATHOLOGIC VARIANT OF SQUAMOUS CELL CARCINOMA. ALOIZIO PREMOLI MACIEL, VICTOR TIEGHI-NETO, CARLA RENATA SANOMIYA IKUTA, LUIZ ANTONIO DE ASSIS TAVEIRA, JOSÉ BURGOS PONCE, PAULO SÉRGIO DA SILVA SANTOS, CÁSSIA MARIA FISCHER RUBIRA. Verrucous carcinoma oral is a variety of epidermoid carcinoma of the oral cavity and presents as a warty growth in patients who have a history of tobacco use. A 93-year-old female patient complained of a “wound in the palate” with 4 months of evolution. The patient had a history of skin cancer 5 years ago and she was a smoker. Intraoral examination revealed an irregular plaque, cauliflower-like, in the palatal region. Based on the clinical examination, a provisional diagnosis of verrucous carcinoma was made. Biopsy in 2 different areas revealed a verrucous carcinoma. After surgical treatment, the final diagnosis was squamous cell carcinoma. Clinicians need to be aware that some apparently verrucous-type lesions, a type that behaves like a verrucous carcinoma, but differently showing a squamous cell carcinoma. In essence, it appears that the same oncogenic stimuli acting on the large area of the oral mucosa, specially related to tobacco, can produce both verrucous carcinoma and malignant squamous cell carcinoma.
CPP133 - SUBGEMMAL NEUROGENOUS PLAQUE: A CASE REPORT WITH EMPHASIS ON CLINICAL AND HISTOPATHOLOGIC ASPECTS. DÁUREA ADÍLIA CÓBE SENA, DEBORAH GONDIM LAMBERT MOREIRA, AMANDA KATARINNY
OOOO August 2017 GOES GONZAGA, ALAN DE QUEIROZ FERNANDES, RODRIGO PORPINO MAFRA, ANA MIRYAM COSTA DE MEDEIROS, LÉLIA MARIA GUEDES QUEIROZ. Subgemmal neurogenous plaque (SNP) is an anatomic structure characterized as a papule similar in color to the adjacent mucosa, located in the posterior lateral border of the tongue. The present report describes the case of a 77-year-old male patient who presented with an asymptomatic erythematous with slight increase in volume in the tongue near circumvallate papillae, measuring 12 mm diameter. In anamnesis, the patient denied oral trauma, systemic diseases and regular use of medications and claimed to be a former smoker. The patient was referred for biopsy and histopathologic analysis revealed a plexus of fusiform neural cells subjacent to oral epithelium, which showed gustatory buttons. Immunohistochemical analysis was performed and showed positivity for S-100 and AE1/AE3 in fusiform cells and gustatory buttons respectively. Based on these findings, we emphasized the importance of the clinicians’ knowledge about SNP because differential diagnosis can contribute to avoid unnecessary biopsies.
CPP134 - ANGIOLEIOMYOMA OF UPPER LIP: A RARE CASE REPORT. LUIZ ARTHUR BARBOSA DA SILVA, EDUARDO ALONSO CRUZ MONROY, HUGO COSTA NETO, ANA MIRYAM COSTA DE MEDEIROS, PATRÍCIA TEIXEIRA DE OLIVEIRA, EICKA JANINE DANTAS DA SILVEIRA, MÁRCIA CRISTINA DA COSTA MIGUEL. Angioleiomyoma is a benign tumor originating from vascular smooth muscle, which rarely occurs in the oral cavity. When found in the oral mucosa, angioleiomyomas most commonly affect the lips, followed by the tongue, cheeks and palate. The rarity of the tumor is likely because of the paucity of smooth muscle in the oral cavity, the primary source of smooth muscle being the tunica media of blood vessels. Herein we report a 44year-old male patient, referred to a diagnosis center with painless lesion, of lobulated surface, with a fibrous consistency and firm upon palpation. The differential diagnosis included a canalicular adenoma and Pleomorphic adenoma. Surgical excision of the lesion was performed. Moderate bleeding was noted and controlled with pressure on the area. Histopathologic study and immunohistochemistry study (SMA, Desmin, Caldesmon, CD34 and S100) confirmed the diagnosis of Angioleiomyoma. No complications were observed and there was no recurrence after a 1 year follow-up.
CPP135 - CONSERVATIVE TREATMENT OF NON-SYNDROMIC KERATOCYSTIC ODONTOGENIC TUMOR OF MAXILLA IN PEDIATRIC PATIENT. CRISTINA RAMOS DE PAIVA, ELIANE DE OLIVEIRA ARANHA RIBEIRO, GIMOL BENCHIMOL DE RESENDE PRESTES, KEULY SOUSA SOARES, ALESSANDRA SALINO, TIAGO NOVAES PINHEIRO. Herein we report a case of conservative treatment of a large Keratocystic Odontogenic Tumor in a non-syndromic in pediatric patient. An 8-year-old male patient was referred to the oral medicine service from the pediatrics service because of a volumetric expansion in the zygomatic region, associated with pain on palpation. CT scan examination showed a well-circumscribed hypodense lesion, unrelated to the neighboring teeth. Fine needle aspiration revealed a yellowish, bright bloody content. The cytopathologic examination suggested an odontogenic cystic
CPP131 - METASTATIC CARCINOMA IN THE RETROMOLAR AREA: A CASE REPORT. DEBORAH LÚCIA LIMA DA COSTA, PAULO BENEVIDES DOS SANTOS, ADELAIDE PORTELA, FÁBIO FRANCESCONI, THAÍSE DA ROCHA CAVALCANTI, LUCIANA BOTINELLY MENDONÇA FUJIMOTO, JECONIAS CÂMARA. Oral cavity metastases are extremely rare, and comprise 1% of all mouth malignant neoplasms. A 74-year-old female patient with a history of breast cancer underwent mastectomy with axillary dissection, chemotherapy, and radiotherapy 11 years ago presented in 2014 with a lesion in the scalp diagnosed as metastatic ductal breast carcinoma. In 2015 she presented with an intraoral nodule, sessile, not ulcerated in the retromolar area, and a firm and fixed cervical node. An incisional biopsy of intraoral lesion was performed and histopathologic analysis revealed neoplastic lesion, characterized by proliferation of epithelioid cells arranged to form ductal structures, sometimes with cribriform appearance and diagnosis of metastatic adenocarcinoma. Immunohistochemical analysis showed positivity for cytokeratin 7, GATA-3, and estrogen receptor, thus confirming the diagnosis of metastatic ductal breast carcinoma. The patient is being treated with chemotherapy and radiotherapy for disease control.
CPP132 - VERRUCOUS CARCINOMA AS A CLINICOPATHOLOGIC VARIANT OF SQUAMOUS CELL CARCINOMA. ALOIZIO PREMOLI MACIEL, VICTOR TIEGHI-NETO, CARLA RENATA SANOMIYA IKUTA, LUIZ ANTONIO DE ASSIS TAVEIRA, JOSÉ BURGOS PONCE, PAULO SÉRGIO DA SILVA SANTOS, CÁSSIA MARIA FISCHER RUBIRA. Verrucous carcinoma oral is a variety of epidermoid carcinoma of the oral cavity and presents as a warty growth in patients who have a history of tobacco use. A 93-year-old female patient complained of a “wound in the palate” with 4 months of evolution. The patient had a history of skin cancer 5 years ago and she was a smoker. Intraoral examination revealed an irregular plaque, cauliflower-like, in the palatal region. Based on the clinical examination, a provisional diagnosis of verrucous carcinoma was made. Biopsy in 2 different areas revealed a verrucous carcinoma. After surgical treatment, the final diagnosis was squamous cell carcinoma. Clinicians need to be aware that some apparently verrucous-type lesions, a type that behaves like a verrucous carcinoma, but differently showing a squamous cell carcinoma. In essence, it appears that the same oncogenic stimuli acting on the large area of the oral mucosa, specially related to tobacco, can produce both verrucous carcinoma and malignant squamous cell carcinoma.
CPP133 - SUBGEMMAL NEUROGENOUS PLAQUE: A CASE REPORT WITH EMPHASIS ON CLINICAL AND HISTOPATHOLOGIC ASPECTS. DÁUREA ADÍLIA CÓBE SENA, DEBORAH GONDIM LAMBERT MOREIRA, AMANDA KATARINNY
OOOO August 2017 GOES GONZAGA, ALAN DE QUEIROZ FERNANDES, RODRIGO PORPINO MAFRA, ANA MIRYAM COSTA DE MEDEIROS, LÉLIA MARIA GUEDES QUEIROZ. Subgemmal neurogenous plaque (SNP) is an anatomic structure characterized as a papule similar in color to the adjacent mucosa, located in the posterior lateral border of the tongue. The present report describes the case of a 77-year-old male patient who presented with an asymptomatic erythematous with slight increase in volume in the tongue near circumvallate papillae, measuring 12 mm diameter. In anamnesis, the patient denied oral trauma, systemic diseases and regular use of medications and claimed to be a former smoker. The patient was referred for biopsy and histopathologic analysis revealed a plexus of fusiform neural cells subjacent to oral epithelium, which showed gustatory buttons. Immunohistochemical analysis was performed and showed positivity for S-100 and AE1/AE3 in fusiform cells and gustatory buttons respectively. Based on these findings, we emphasized the importance of the clinicians’ knowledge about SNP because differential diagnosis can contribute to avoid unnecessary biopsies.
CPP134 - ANGIOLEIOMYOMA OF UPPER LIP: A RARE CASE REPORT. LUIZ ARTHUR BARBOSA DA SILVA, EDUARDO ALONSO CRUZ MONROY, HUGO COSTA NETO, ANA MIRYAM COSTA DE MEDEIROS, PATRÍCIA TEIXEIRA DE OLIVEIRA, EICKA JANINE DANTAS DA SILVEIRA, MÁRCIA CRISTINA DA COSTA MIGUEL. Angioleiomyoma is a benign tumor originating from vascular smooth muscle, which rarely occurs in the oral cavity. When found in the oral mucosa, angioleiomyomas most commonly affect the lips, followed by the tongue, cheeks and palate. The rarity of the tumor is likely because of the paucity of smooth muscle in the oral cavity, the primary source of smooth muscle being the tunica media of blood vessels. Herein we report a 44year-old male patient, referred to a diagnosis center with painless lesion, of lobulated surface, with a fibrous consistency and firm upon palpation. The differential diagnosis included a canalicular adenoma and Pleomorphic adenoma. Surgical excision of the lesion was performed. Moderate bleeding was noted and controlled with pressure on the area. Histopathologic study and immunohistochemistry study (SMA, Desmin, Caldesmon, CD34 and S100) confirmed the diagnosis of Angioleiomyoma. No complications were observed and there was no recurrence after a 1 year follow-up.
CPP135 - CONSERVATIVE TREATMENT OF NON-SYNDROMIC KERATOCYSTIC ODONTOGENIC TUMOR OF MAXILLA IN PEDIATRIC PATIENT. CRISTINA RAMOS DE PAIVA, ELIANE DE OLIVEIRA ARANHA RIBEIRO, GIMOL BENCHIMOL DE RESENDE PRESTES, KEULY SOUSA SOARES, ALESSANDRA SALINO, TIAGO NOVAES PINHEIRO. Herein we report a case of conservative treatment of a large Keratocystic Odontogenic Tumor in a non-syndromic in pediatric patient. An 8-year-old male patient was referred to the oral medicine service from the pediatrics service because of a volumetric expansion in the zygomatic region, associated with pain on palpation. CT scan examination showed a well-circumscribed hypodense lesion, unrelated to the neighboring teeth. Fine needle aspiration revealed a yellowish, bright bloody content. The cytopathologic examination suggested an odontogenic cystic