The importance of the electrocardiographic study made with the exercise test is emphasized as the only safe means of establishing the diagnosis of latent coronary ostial stenosis. Routine use of the electrocardiographic study and exercise test in early cases with a systematic follow-up in subsequent years is urged in order to discover cardiovascular syphilis at an earlier stage than has been possible heretofore. AUTHOR.
Weinstein, J. : Public Health Aspects of Cardiovascular City. New York State J. Med. 41: 234, 1941.
Syphilis
An analysis of the available morbidity and mortality statistics of the economic aspects of cardiovascular syphilis in New York disease is an important public health problem. From a practical place in New York decade and a half. nized early enough circulatory system.
in New York
and a consideration City show that this
public health point of view no conspicuous change has taken City in the reported deaths from aortic aneurysm during the past Apparently, syphilis in a number of persons has not been recogor properly treated in the past to avoid later complications in the
The outlook for cardiovascular syphilis in the treatment of syphilis in its earliest possible stage adequate period of time.
future is full of promise, and is continued intensively for an
Past experience has taught us that aortic syphilis will develop in a certain number of persons despite energetic and prolonged treatment of early syphilis. In this respect more knowledge is wanted, and further efforts in the direction of research on syphilis treatment, and its evaluation are indicated. AUTHOR.
Ritchie, G. : Metastatic
Tumors
of the
Myocardium.
Am.
J. Path.
17: 483, 1941.
Bixteen cases of metastatic tumors of the myocardium are reported, with a tabulaThirteen different types of primary tion of certain features and a brief discussion. tumors were represented, and there was considerable variation as to route of In no case had a clinical diagnosis metastasis and mode of growth within the muscle. of cardiac invasion been made. AUTHOR.
Wakerlin, G. E., and Johnson, C. A.: The Effect of Renin on Experimental Hypertension in the Dog. J. A. M. A. 117: 416, 1941. Daily reductions inactivated
Renal
intramuscular injections of hog renin for four months produced striking in the blood pressures of dogs with renal hypertension, whereas heathog renin and active dog renin were without effect.
No detected toxic manifestations resulted from the injections The sera of the dogs treated the reductions in blood pressures. not the sera of the dogs given injections of inactivated hog neutralized the acute pressor effect of renin (antirenin).
of renin or from with hog renin, but renin or dog renin,
Daily intramuscular injections of hog renin into two normotensive dogs before and after constriction of the renal arteries prevented the development of hypertension. The mechanism of these therapeutic and prophylactic effects of hog renin in experimental renal hypertension in the dog is not clear. Most probably an immune (antihormone?) response to heterologous hog renin is involved. AUTHORS.