Methergine (synthetic lysergic acid derivative), a new oxytocic

Methergine (synthetic lysergic acid derivative), a new oxytocic

463 ABSTRACTS operations were done under combined local infiltration and block anesthesia. The technique of the operative procedure, which is a modi...

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463

ABSTRACTS

operations were done under combined local infiltration and block anesthesia. The technique of the operative procedure, which is a modification of Diokinson’s operation, is well illustrated and the various stages described in detail. Briefly, it consists of a vaginal hysterectomy, advancement of the bladder above and beyond the joined stumps of the broad and round ligaments, and finally an anterior and post.erior repair. The results are reported as satisfactory in 87.33 per cent of the cases. Recurrences were present in 12.ti6 per cent and are reported as follows: Cases Cystoceles Rectoceles Enteroceles Incomplete Urethrocele

Bornas, 1944.

Pablo :

vagina

Myomectomy

Per

36 28 5 5 2

as

Conservative

Surgery,

cent

6.0 4.6 0.83 0.83 0.33 L. M. HELLMAN. Semana

med.

51:

1334,

The author uses temporary ligation of the uterine art.eries and makes an anteroposterior lozenge-shaped incision embracing the tumor zone as in fundus resection. it restores normal uterine form when If necessary, this incision can be prolonged; the organ is reconstructed. The author excises a wedge of muscle, conserving the myoperitoneal and myoendometrial planes. Then he sutures the myomucous flaps, obliterates the dead space of the extirpated tissue with a few interrupted sutures, and approximates the myoperitoneal flaps, being careful to adjust them correctly. J. P. GREENHILL.

Labor, Management, Phaneuf, L. E.: Ruptured Uterus Pollowing of the Uterus,.Am. J. Surg. 56: 379, 1942.

Complications the Spinelli

Operation

for Inversion

The patient was 30 years old and had had two forceps deliveries. Ten weeks following the termination of her second pregnancy it was discovered that she was suffering from an inversion of the uterus which the author repaired, performing a Spinelli operation. Recovery was without incident. She became gravid for the third time two years after the operation, and because of the danger of rupture of the uterus, the author planned delivery by cesarean se&on well before her expected date of confinement. However, three days before that date, the patient suddenly showed evidence of an acute abdominal accident, and at operation a rupture of the uterus was found for which, following removal of a living fetus, a Porro operation was done. Convalescence for both mother and baby was normal. Pathologically, incision in the rupture of the

the rupture was found to have occurred along the line of previous uterus incident to the Spinelli operation. There was degeneration and scar with digestion of collagen in this area. FUNK SPIELMAN.

Tollefson, Donald Oxytocic., West.

cf.:

Methergine J. Surg. 52: 383,

(Synthetic 1944.

Lysergic

Acid Derivative),

a New

Methergine is a synthetic ergonovine whose activity on, the animal and human uterus has been demonstrated. Unlike ergotamine it does not have any inhibiting effect upon the adrenaline response of isolated rabbit uteri. No evidence of toxicity has been demonstrated. In 200 patients who had received nembutal and scopolamine in amnesic doses during labor, 1 C.C. of methergine was given intravenously as soon as separation of the placenta was in progress. Action of the oxy tocic was rapid, averaging 48 seconds. Estimation of the blood loss in this series was thought to average 98 C.C. During the puerperium methergine has been given in doses of 3 tablets daily and the lochia was noticeably reduced. The author’s experience with the administration intravenously immediately after delivery of the shoulders has not been good. He recommends administration immediately after npontaneous separation of the placenta has begun. WILLIAM BICKERS.