Methods in neurobiology

Methods in neurobiology

85 cekegters, 30 (I~82) 85--g7 Et~vier/Nc~rthaHel.~nd gcieng.ificFabl~shers L;d. ea ~ : s~Mes ~ gk A , V o L 3~ E-di~ed by,Freaqcesco Lenc~ an...

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85

cekegters, 30 (I~82) 85--g7 Et~vier/Nc~rthaHel.~nd gcieng.ificFabl~shers L;d.

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:

s~Mes

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gk

A , V o L 3~

E-di~ed by,Freaqcesco Lenc~ and Giu~iano C~iombett~ Plenum Press, lqe~! York, 1980, $45,00 in U.S.A. and C~nad# ~nd $5.4.00 outside U,S.A, a~d Ccmad~'~

T h e book .coRnets the ~tures presented :ufing the NATO Advanced Study Institute he~d in Versi~ia, !taly, S~#ten~b4.'-r 3 - ! 4 , 1979o ~t.g~vcs a go~d acco~ni of the presem state of: the,"~a,~ o~" this sometimes st~ghfiy neg~ected.area~ ~t starts with a number o f arficies a b o r t .the phe~omenoiogy o f the dKferen~ photomo~fie responses of different organk~m.*~and ieads to a discussion of the mcdecalar p~@~:esses in the causai chain t~f theph,~totraasducfion mechanism. ][t.~:~ci~des ctescfipfions of ~:he methods to study different s~eps of the transdu~ion mechanism. What is knowr~ and ~ h a t ~s still unknown is developed rather deafly h~ most articles~ Read~ng ~he book. one finds tha~ the photopigments for sevcra~ pho~omoto~" r e s ~ n s e s are rdativd-: wd~ known° tin contrast ~o this, the imermediate s~cps of the tra~ed~action mechani,;ms are s i n quite obscure. A corfformador~a~ change oi: a membrane protein may be an importam early step h~ t~ae transd~cfio~ chum, The fina! step acts on a motile sys~:em. In ma~y cases the cha~ge in ir4~acei~u~ar caic~uv~~ ion concentration ig ir~volved as an importam ca~sN step. The meebamsm of Gen~tm ~s o~¢ s~;~,ps adoption is in most cases not y et well investigated, " '. '" ~aa1:: ~'':'o " ° m tSe causal chain seems to be promising for the futu e. The book is worth readir~g not o~iy for those w~o work - or wang to work = i~,~ the field o f photoreception of anet£rat orga~a~sms, but aiso for ti"~ose ~'ho sw,dy photo~eception in higher organisms. ~

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