The Journal of the American Association of Gynecologic Laparoscopists
Images in Endoscopy
Miliary Tuberculous Peritonitis Athanasios Protopapas, M.D., and Spyros D. Milingos, M.D.
FIGURE 1. Unexplained pyrexical ascites in a postmenopausal women, in whom the diagnosis of miliary peritoneal tuberculosis was confirmed by biopsy tissues obtained at laparoscopy. Note disseminated spread of whitish tuberculosis deposits. Top left: anterior abdominal wall peritoneum. Top right: milia and free fluid in right subdiaphragmatic space. Bottom left: confluent lesions in pelvic peritoneum. Bottom right: laparoscopic biopsy specimen from pouch of Douglas. (J Am Assoc Gynecol Laparosc 10(2):139, 2003)
Primary peritoneal tuberculosis is a rare disease and is usually associated with ascites and elevated CA 125 levels, mimicking advanced ovarian cancer. Preoperative diagnosis can be extremely difficult, because acid-fast stains and special cultures of ascitic fluid
for Mycobacterium tuberculosis are frequently negative. Confirmation of the diagnosis commonly requires histologic examination of biopsy specimens, in which epithelioid granulomas with central caseous necrosis can be identified.