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Millipore opens production facility and unveils bioreactor
NEWS International Products specialises in the manufacture and distribution of environmentfriendly speciality cleaners and temporary assembly lubricants. Contact: International Products Corp, 201 Connecticut Drive, Burlington NJ 08016, USA. Tel: +1 609 386 8770, www.ipcol.com/membranetest
Siemens’ Protegra CS produces Type II water for laboratories
U
S-based Siemens Water Technologies has introduced the Protegra CS water system. Combining reverse osmosis (RO) and continuous electrodeionisation (CEDI) technologies, it produces consistent ASTM Type II grade pure water from a soft water source. Available in four models, with flow rates of 120–750 l/h, the Protegra CS system can supply pure water to an entire building or to one laboratory with multiple points of use. The system uses a high-capacity RO membrane and is designed to remove dissolved solids from the feedwater source while sending minimal reject water to drain. The system also uses a single CEDI module that continually regenerates, eliminating the use of costly chemicals. The maintenance-free CEDI module uses ion-exchange resins and electricity to remove ions from water – resulting in a purified water with a resistivity up to 17 megohm-cm. Protegra CS is ideally suited for high-flow applications, such as feeding autoclaves, glassware washers and environmental chambers, says the company. All system components are contained in a single compact cabinet with removable side panels for easy maintenance. These eco-friendly systems can be fully integrated into a central purification system or a loop make-up and delivery system. Water quality sensors throughout the system send data to an easy-to-read control panel display located on the front of the system cabinet.
Contact: Siemens Water Technologies, 181 Thorn Hill Road, Warrendale, PA 15086, USA. Tel: +1 724 772 0044, www.industry.siemens.com Siemens AG, Industry Solutions, Schuhstrasse 60, D-91052 Erlangen, Germany. Tel: +49 9131 70, www.industry.siemens.com
6
Membrane Technology
Millipore opens production facility and unveils bioreactor
M
illipore Corp has officially opened a new facility in Danvers, Massachusetts, for manufacturing products for bioprocess applications. The US firm, which provides technology, tools and services for the life science industry, has also unveiled its single-use Mobius CellReady 3L bioreactor. The facility, covering an area of over 2700 m2 (30 000 ft2), will make a wide range of the company’s Mobius single-use products that are used in bio-pharmaceutical manufacturing, including components of the recently introduced Mobius FlexReady Solutions (see Membrane Technology May 2009, page 2). Commenting on the facility, Martin Madaus, Chairman, President and Chief Executive Officer, Millipore, said: ‘The opening of our Danvers manufacturing facility is positive not only for Millipore, but also for the state of Massachusetts. We made a decision to move manufacturing of this product line from California and bring it to Massachusetts, which will mean additional jobs in the state, not to mention an exciting, innovative technology that is already having an impact on bio-pharmaceutical manufacturing.’ Millipore expects the new facility will employ 120 people before the end of 2009. The company currently employs over 1000 members of staff in Massachusetts and almost 6000 worldwide. Millipore’s Mobius FlexReady Solutions are made up of single-use assemblies (Flexware), separation devices, and process-ready hardware systems optimised for clarification, media and buffer preparation, tangential flow filtration and virus filtration. The opening of the production facility also marks the official launch of Millipore’s ‘Go Mobius’ roadshow – a mobile trade show that will travel throughout the USA demonstrating and promoting the firm’s single-use and core device technologies (see ‘In Brief ’ on page 7). Other news reveals that Millipore has introduced its new Mobius CellReady 3L Bioreactor at the European Society for Animal Cell Technology’s conference, which was held recently in Dublin, Ireland. This ready-to-use, three-litre bioreactor demonstrates all the benefits typically associated with single-use processing, while incorporating standard design features familiar to customers already using bench-top, stirred-tank bioreactors. ‘Now process development scientists have a bench-top, single-use bioreactor that is ready
to use – right out of the box – so they can maximise their time in the laboratory,’ said Dr Andrew Bulpin, Vice President, Upstream Processing, Millipore. Designed to replace traditional bench-top bioreactors made from glass, the CellReady unit has a standard stirred-tank format for use in the development and optimisation of cell culture processes. This vessel design provides a higher degree of predictability during process scale-up than formats that use alternative receptacle structures and agitation methods, says Millipore. It is also compatible with most bench-top bioreactor control systems. By eliminating time-consuming steps associated with cleaning, assembly and sterilisation it significantly reduces the turnaround time typically associated with glass bioreactors. The CellReady unit was co-developed under agreement with Applikon Biotechnology BV, a Dutch firm that specialises in traditional, glass and stainless steel bench-scale bioreactors specifically designed to be used in bio-pharmaceutical process development applications. Arthur Oudshoorn, Managing Director, Applikon Biotechnology, commented: ‘The CellReady Bioreactor is the first and only singleuse bioreactor that truly mimics the characteristics of ‘‘autoclavable’’ bioreactors, which have evolved and proven their performance over decades. As such, the Mobius CellReady Bioreactor is bound to provide the long-awaited breakthrough of stirred-tank single-use bioreactors.’ Contact: Millipore Corp, 290 Concord Road, Billerica, MA 01821, USA. Tel: +1 978 715 4321, www.millipore.com
Desalination vessel adopts ERI’s PX technology
E
nergy Recovery Inc (ERI) of San Leandro, California, USA, a designer and developer of energy-recovery systems for desalination, has announced that Water Standard is planning to use its PX Pressure Exchanger device in its first sea-water desalination vessel (SDV). Water Standard, which is based in Houston, Texas, USA, builds and operates vessels that deliver desalinated water to clients onshore and to the offshore energy industry. ‘ERI’s PX energy-recovery device enables us to convert sea water to drinking water more affordably,’ commented Amanda Brock, Chief Executive Officer, Water Standard. ‘The cost of water production is a key metric to the success of our initiative and ERI is a
August 2009
Siemens’ Protegra CS produces Type II water for laboratories
U
S-based Siemens Water Technologies has introduced the Protegra CS water system. Combining reverse osmosis (RO) and continuous electrodeionisation (CEDI) technologies, it produces consistent ASTM Type II grade pure water from a soft water source. Available in four models, with flow rates of 120–750 l/h, the Protegra CS system can supply pure water to an entire building or to one laboratory with multiple points of use. The system uses a high-capacity RO membrane and is designed to remove dissolved solids from the feedwater source while sending minimal reject water to drain. The system also uses a single CEDI module that continually regenerates, eliminating the use of costly chemicals. The maintenance-free CEDI module uses ion-exchange resins and electricity to remove ions from water – resulting in a purified water with a resistivity up to 17 megohm-cm. Protegra CS is ideally suited for high-flow applications, such as feeding autoclaves, glassware washers and environmental chambers, says the company. All system components are contained in a single compact cabinet with removable side panels for easy maintenance. These eco-friendly systems can be fully integrated into a central purification system or a loop make-up and delivery system. Water quality sensors throughout the system send data to an easy-to-read control panel display located on the front of the system cabinet.
Contact: Siemens Water Technologies, 181 Thorn Hill Road, Warrendale, PA 15086, USA. Tel: +1 724 772 0044, www.industry.siemens.com Siemens AG, Industry Solutions, Schuhstrasse 60, D-91052 Erlangen, Germany. Tel: +49 9131 70, www.industry.siemens.com
6
Membrane Technology
Millipore opens production facility and unveils bioreactor
M
illipore Corp has officially opened a new facility in Danvers, Massachusetts, for manufacturing products for bioprocess applications. The US firm, which provides technology, tools and services for the life science industry, has also unveiled its single-use Mobius CellReady 3L bioreactor. The facility, covering an area of over 2700 m2 (30 000 ft2), will make a wide range of the company’s Mobius single-use products that are used in bio-pharmaceutical manufacturing, including components of the recently introduced Mobius FlexReady Solutions (see Membrane Technology May 2009, page 2). Commenting on the facility, Martin Madaus, Chairman, President and Chief Executive Officer, Millipore, said: ‘The opening of our Danvers manufacturing facility is positive not only for Millipore, but also for the state of Massachusetts. We made a decision to move manufacturing of this product line from California and bring it to Massachusetts, which will mean additional jobs in the state, not to mention an exciting, innovative technology that is already having an impact on bio-pharmaceutical manufacturing.’ Millipore expects the new facility will employ 120 people before the end of 2009. The company currently employs over 1000 members of staff in Massachusetts and almost 6000 worldwide. Millipore’s Mobius FlexReady Solutions are made up of single-use assemblies (Flexware), separation devices, and process-ready hardware systems optimised for clarification, media and buffer preparation, tangential flow filtration and virus filtration. The opening of the production facility also marks the official launch of Millipore’s ‘Go Mobius’ roadshow – a mobile trade show that will travel throughout the USA demonstrating and promoting the firm’s single-use and core device technologies (see ‘In Brief ’ on page 7). Other news reveals that Millipore has introduced its new Mobius CellReady 3L Bioreactor at the European Society for Animal Cell Technology’s conference, which was held recently in Dublin, Ireland. This ready-to-use, three-litre bioreactor demonstrates all the benefits typically associated with single-use processing, while incorporating standard design features familiar to customers already using bench-top, stirred-tank bioreactors. ‘Now process development scientists have a bench-top, single-use bioreactor that is ready
to use – right out of the box – so they can maximise their time in the laboratory,’ said Dr Andrew Bulpin, Vice President, Upstream Processing, Millipore. Designed to replace traditional bench-top bioreactors made from glass, the CellReady unit has a standard stirred-tank format for use in the development and optimisation of cell culture processes. This vessel design provides a higher degree of predictability during process scale-up than formats that use alternative receptacle structures and agitation methods, says Millipore. It is also compatible with most bench-top bioreactor control systems. By eliminating time-consuming steps associated with cleaning, assembly and sterilisation it significantly reduces the turnaround time typically associated with glass bioreactors. The CellReady unit was co-developed under agreement with Applikon Biotechnology BV, a Dutch firm that specialises in traditional, glass and stainless steel bench-scale bioreactors specifically designed to be used in bio-pharmaceutical process development applications. Arthur Oudshoorn, Managing Director, Applikon Biotechnology, commented: ‘The CellReady Bioreactor is the first and only singleuse bioreactor that truly mimics the characteristics of ‘‘autoclavable’’ bioreactors, which have evolved and proven their performance over decades. As such, the Mobius CellReady Bioreactor is bound to provide the long-awaited breakthrough of stirred-tank single-use bioreactors.’ Contact: Millipore Corp, 290 Concord Road, Billerica, MA 01821, USA. Tel: +1 978 715 4321, www.millipore.com
Desalination vessel adopts ERI’s PX technology
E
nergy Recovery Inc (ERI) of San Leandro, California, USA, a designer and developer of energy-recovery systems for desalination, has announced that Water Standard is planning to use its PX Pressure Exchanger device in its first sea-water desalination vessel (SDV). Water Standard, which is based in Houston, Texas, USA, builds and operates vessels that deliver desalinated water to clients onshore and to the offshore energy industry. ‘ERI’s PX energy-recovery device enables us to convert sea water to drinking water more affordably,’ commented Amanda Brock, Chief Executive Officer, Water Standard. ‘The cost of water production is a key metric to the success of our initiative and ERI is a
August 2009