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the design of chiral stationary phases (Pirkle and Pochapsky). There is a comprehensive subject index.
Nelu Grinberg (Ed.), Modern Thzn-Layer Chromatography (Chromatographzc Sczence Serzes, Vol. 52), Dekker, New York, 1990 (ISBN 0-8247-81384). xti + 490 pp. Price US$99.75 (USA and Canada), US$119.50 (all other countries). Thin-layer chromatography (TLC) is widely used as a means of achieving rapid, mgh-resolunon separations at relatively low cost. Interest in the technique has always been high but, judging by the number of new books on the SubJect that have recently appeared, there is much increased activity in the subJect. The present text provides a comprehensive survey of the subject (stationary and mobile phases, theory, quantitation and instrumentation), including “special techmques” such as chiral separation, gradient techniques and contmuous and forced-flow TLC. The maJor authors are Grinberg, Gocan and Szepesi, with contributions from a number of others, including Touchstone, himself the author of a recent book on TLC
Milan Popl, Jan Fahnnch and Vlastimil Tatar, Chromatographzc Analysis of Alkaloids (Chromatographzc Science Serzes, Vol. 53) Dekker, New York, 1990 (ISBN O-8247-8140-6). viii + 667 pp. Price US$lSO.OO (USA and Canada), US$lSO.OO (all other countries).
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tions, which includes a tabulated summary of the applications, occupymg 220 pages, detailing chromatographic and detection conditions, compounds separated, samples analysed etc., supported by 490 references published up to 1988. Joseph Sherma and Bernard Fried (Eds.), Handbook of Thzn-Layer Chromatography (Chromatographzc Science Serzes, Vol. 55) Dekker, New York, 1991 (ISBN O-8247-8335-2). viii + 1047 pp. Price US$165.00 (USA and Canada), US$198.00 (all other countries). Hard on the heels of the book on Modern Thzn-Layer Chromatography reviewed above comes thts larger compilation, larger both in the number of pages and the page size. Consequently there is considerably more information in the present volume, especially in its extensive coverage (667 pp.) of applications. These are collected under compound types (amino acids, antibiotics, carbohydrates, inorganics, enantiomers, pesticides, drugs, dyes, vitamins etc., 18 chapters in all), with comprehensive information gtven on methodology as well as considerable amounts of data. The first part of the book covers all aspects of the theory, practice and technology of thin-layer chromatography (TLC) in some depth. Each chapter is written by experts, and it is hard to believe that anythmg significant has been omitted. The illustrations are better than in the above-mentioned text, and overall this book should serve for many years as the source of information on TLC.
Alan Townshend Alkaloids are important natural products, and their isolation from complex mixtures and subsequent analysis are important pharmacologically and clinically. This book provides an extensive account of the uses of chromatography for alkaloid analysis, written by scientists from the Prague Institute of Chemical Technology. It begins with a description of the various types of alkaloids, and of their relevant physlco-chenncal properties. The “meat” of the text concerns gas, liquid and thin-layer chromatographic separations. This is followed by a large chapter on apphca-
T.F. Hartley, Computerzzed Quahty Control Programs for the Analytical Laboratory, Horwood, Chichester, 2nd edn., 1990 (ISBN 0-13-151614-O). 245 pp. Pnce US$59.95. In step wtth the rapid developments m computer equipment, the second edition of this book has appeared less than four years after the first. The main changes include developments that can be accomodated by use of a personal computer